CA2719402A1 - Process for preparation of benzo-fused heteroaryl derivatives - Google Patents

Process for preparation of benzo-fused heteroaryl derivatives Download PDF

Info

Publication number
CA2719402A1
CA2719402A1 CA2719402A CA2719402A CA2719402A1 CA 2719402 A1 CA2719402 A1 CA 2719402A1 CA 2719402 A CA2719402 A CA 2719402A CA 2719402 A CA2719402 A CA 2719402A CA 2719402 A1 CA2719402 A1 CA 2719402A1
Authority
CA
Canada
Prior art keywords
formula
compound
yield
group
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2719402A
Other languages
English (en)
French (fr)
Inventor
Scott A. Ballentine
Laura Reany
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of CA2719402A1 publication Critical patent/CA2719402A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
CA2719402A 2008-03-26 2008-03-26 Process for preparation of benzo-fused heteroaryl derivatives Abandoned CA2719402A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/058247 WO2009120192A2 (en) 2008-03-26 2008-03-26 Process for the preparation of benzo-fused heteroaryl derivatives

Publications (1)

Publication Number Publication Date
CA2719402A1 true CA2719402A1 (en) 2009-10-01

Family

ID=40351717

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2719402A Abandoned CA2719402A1 (en) 2008-03-26 2008-03-26 Process for preparation of benzo-fused heteroaryl derivatives

Country Status (13)

Country Link
EP (1) EP2280951A2 (es)
JP (1) JP2011517448A (es)
KR (1) KR20100126536A (es)
CN (1) CN101981023A (es)
AU (1) AU2008353492A1 (es)
BR (1) BRPI0822396A2 (es)
CA (1) CA2719402A1 (es)
EA (1) EA201071121A1 (es)
EC (1) ECSP10010498A (es)
IL (1) IL208223A0 (es)
MX (1) MX2010010597A (es)
WO (1) WO2009120192A2 (es)
ZA (1) ZA201007610B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
JP2008545650A (ja) 2005-05-20 2008-12-18 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ スルファミド誘導体の製造方法
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
EA200870556A1 (ru) 2006-05-19 2009-06-30 Янссен Фармацевтика Н.В. Комбинированная терапия в лечении эпилепсии и родственных расстройств
NZ590682A (en) * 2008-06-23 2012-09-28 Janssen Pharmaceutica Nv Crystalline form of (2S)-(-)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide
US8815939B2 (en) 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
CA2850513A1 (en) 2011-09-29 2013-04-04 Janssen Pharmaceutica Nv Process for the preparation of sulfamide derivatives
EP2760852A1 (en) 2011-09-29 2014-08-06 Janssen Pharmaceutica, N.V. Improved process for the preparation of sulfamide derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120758A (en) * 1991-02-08 1992-06-09 Ciba-Geigy Corporation Certain benzodioxole, benzodioxane and benzodioxepin derivatives useful as 5-lipoxygenase inhibitors
MY147767A (en) * 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders

Also Published As

Publication number Publication date
ECSP10010498A (es) 2010-10-30
CN101981023A (zh) 2011-02-23
AU2008353492A1 (en) 2009-10-01
BRPI0822396A2 (pt) 2019-09-24
EA201071121A1 (ru) 2011-04-29
MX2010010597A (es) 2010-10-25
IL208223A0 (en) 2010-12-30
JP2011517448A (ja) 2011-06-09
WO2009120192A3 (en) 2010-01-21
EP2280951A2 (en) 2011-02-09
WO2009120192A2 (en) 2009-10-01
ZA201007610B (en) 2012-04-25
KR20100126536A (ko) 2010-12-01

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20140326