KR20100111282A - 당쇄 관련 유전자, 및 그의 이용 - Google Patents
당쇄 관련 유전자, 및 그의 이용 Download PDFInfo
- Publication number
- KR20100111282A KR20100111282A KR1020107016694A KR20107016694A KR20100111282A KR 20100111282 A KR20100111282 A KR 20100111282A KR 1020107016694 A KR1020107016694 A KR 1020107016694A KR 20107016694 A KR20107016694 A KR 20107016694A KR 20100111282 A KR20100111282 A KR 20100111282A
- Authority
- KR
- South Korea
- Prior art keywords
- sirna
- tissue
- manufactured
- gene
- mouse
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/13—Transferases (2.) transferring sulfur containing groups (2.8)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/91194—Transferases (2.) transferring sulfur containing groups (2.8)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007336518 | 2007-12-27 | ||
| JPJP-P-2007-336518 | 2007-12-27 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157037089A Division KR20160007671A (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20100111282A true KR20100111282A (ko) | 2010-10-14 |
Family
ID=40823968
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177023558A Active KR101926292B1 (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
| KR1020187034630A Ceased KR20180132162A (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
| KR1020107016694A Ceased KR20100111282A (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
| KR1020167022756A Ceased KR20160103554A (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
| KR1020157037089A Withdrawn KR20160007671A (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
| KR1020197037818A Active KR102244872B1 (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177023558A Active KR101926292B1 (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
| KR1020187034630A Ceased KR20180132162A (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167022756A Ceased KR20160103554A (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
| KR1020157037089A Withdrawn KR20160007671A (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
| KR1020197037818A Active KR102244872B1 (ko) | 2007-12-27 | 2008-12-26 | 당쇄 관련 유전자, 및 그의 이용 |
Country Status (7)
| Country | Link |
|---|---|
| US (6) | US20110027248A1 (enExample) |
| EP (4) | EP3360556B1 (enExample) |
| JP (3) | JP4585611B2 (enExample) |
| KR (6) | KR101926292B1 (enExample) |
| CN (2) | CN101965196A (enExample) |
| SG (2) | SG10201402793PA (enExample) |
| WO (1) | WO2009084232A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5547964B2 (ja) * | 2007-06-29 | 2014-07-16 | 株式会社ステリック再生医科学研究所 | 生理活性物質を定着および発現させる方法 |
| DK2460403T3 (da) | 2009-07-31 | 2019-08-19 | Smc Global Asset Inc | Steatohepatitis lever cancer model mus |
| TWI627965B (zh) | 2011-11-18 | 2018-07-01 | 日東電工股份有限公司 | 腸道纖維化處置劑 |
| EP2876162A4 (en) * | 2012-07-17 | 2016-03-16 | Stelic Institute&Co | MUCOSA CURE PROMOTER |
| BR112015027322A8 (pt) * | 2013-05-01 | 2018-01-02 | Isis Pharmaceuticals Inc | Compostos antissenso conjugados e sua utilização |
| JP6302183B2 (ja) * | 2013-07-12 | 2018-03-28 | 株式会社エンザミン研究所 | アディポサイトカイン産生バランス調整剤及び脂肪組織の炎症・酸化ストレス抑制剤並びに脂肪組織のマクロファージ浸潤抑制剤 |
| WO2016140925A1 (en) | 2015-03-02 | 2016-09-09 | Synthetic Genomics, Inc. | Regulatory elements from labyrinthulomycetes microorganisms |
| WO2017078054A1 (ja) | 2015-11-04 | 2017-05-11 | 株式会社ステリック再生医科学研究所 | RNAi分子とN-アセチル化キトサンとを含む複合体 |
| US10633454B2 (en) | 2016-11-01 | 2020-04-28 | Conagen Inc. | Expression of modified glycoproteins and glycopeptides |
| WO2018106931A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| US20200093850A1 (en) | 2016-12-07 | 2020-03-26 | Stelic Institute & Co., Inc. | Pharmaceutical composition for treatment and prevention of chronic disease |
| EP3600249A1 (en) | 2017-03-30 | 2020-02-05 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a chst15 inhibitor |
| WO2019173226A1 (en) * | 2018-03-05 | 2019-09-12 | Synthetic Genomics, Inc. | Organisms and methods for producing glycomolecules with low sulfation |
| CN109897812B (zh) * | 2019-03-19 | 2021-09-03 | 江南大学 | 一种表达软骨素4-硫酸转移酶基因的重组菌及其应用 |
| JPWO2020225871A1 (enExample) * | 2019-05-08 | 2020-11-12 | ||
| CN116254296A (zh) * | 2023-03-27 | 2023-06-13 | 中国科学院微生物研究所 | 利用昆虫细胞杆状病毒表达系统表达硫酸软骨素修饰酶的方法及应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4571242B2 (ja) * | 1996-07-24 | 2010-10-27 | 生化学工業株式会社 | ヒト由来のグリコサミノグリカンスルホトランスフェラーゼのポリペプチド及びそれをコードするdna |
| WO1998046258A2 (en) * | 1997-04-11 | 1998-10-22 | Beth Israel Deaconess Medical Center, Inc. | Use of chondroitinase in the manufacture of a medicament in the treatment and prevention of mucoid secretions |
| EP1839671A3 (en) * | 1999-12-02 | 2007-10-31 | BioMarin Pharmaceutical Inc. | Attenuation of fibroblast proliferation |
| EP1263459A2 (en) * | 1999-12-02 | 2002-12-11 | Ibex Technologies, Inc. | Attenuation of fibroblast proliferation |
| US6713274B2 (en) * | 2002-05-13 | 2004-03-30 | The Regents Of The University Of California | Method for identifying modulators of sulfotransferase activity |
| EP1541580B1 (en) * | 2002-07-10 | 2013-02-27 | Seikagaku Corporation | Sulfotransferase inhibitors |
| SI2712617T1 (sl) * | 2004-03-12 | 2017-01-31 | Intercept Pharmaceuticals, Inc. | Zdravljenje fibroze z uporabo Fxr ligandov |
| WO2007049361A1 (ja) * | 2005-10-27 | 2007-05-03 | Stelic Corp. | 肝線維化抑制剤 |
| JP2009286695A (ja) * | 2006-09-08 | 2009-12-10 | Stelic Institute Of Regenerative Medicine | 眼線維性血管新生抑制剤 |
| US20090202515A1 (en) * | 2006-09-08 | 2009-08-13 | Stelic Institute Of Regenerative Medicine, Stelic Institute & Co. | Agents for suppressing neural fibrotic degeneration |
| JP5547964B2 (ja) * | 2007-06-29 | 2014-07-16 | 株式会社ステリック再生医科学研究所 | 生理活性物質を定着および発現させる方法 |
-
2008
- 2008-12-26 JP JP2009547912A patent/JP4585611B2/ja active Active
- 2008-12-26 CN CN200880127570XA patent/CN101965196A/zh active Pending
- 2008-12-26 KR KR1020177023558A patent/KR101926292B1/ko active Active
- 2008-12-26 EP EP18151424.1A patent/EP3360556B1/en active Active
- 2008-12-26 WO PCT/JP2008/004025 patent/WO2009084232A1/ja not_active Ceased
- 2008-12-26 EP EP08866254A patent/EP2238987A4/en not_active Withdrawn
- 2008-12-26 KR KR1020187034630A patent/KR20180132162A/ko not_active Ceased
- 2008-12-26 EP EP15194114.3A patent/EP3045178A1/en not_active Withdrawn
- 2008-12-26 SG SG10201402793PA patent/SG10201402793PA/en unknown
- 2008-12-26 KR KR1020107016694A patent/KR20100111282A/ko not_active Ceased
- 2008-12-26 KR KR1020167022756A patent/KR20160103554A/ko not_active Ceased
- 2008-12-26 SG SG10202001748VA patent/SG10202001748VA/en unknown
- 2008-12-26 EP EP20151386.8A patent/EP3673910B1/en active Active
- 2008-12-26 KR KR1020157037089A patent/KR20160007671A/ko not_active Withdrawn
- 2008-12-26 KR KR1020197037818A patent/KR102244872B1/ko active Active
- 2008-12-26 US US12/809,969 patent/US20110027248A1/en not_active Abandoned
- 2008-12-26 CN CN201310495268.2A patent/CN103656644A/zh active Pending
-
2010
- 2010-08-02 JP JP2010173610A patent/JP4751956B2/ja active Active
-
2011
- 2011-05-17 JP JP2011110047A patent/JP5481426B2/ja active Active
-
2013
- 2013-11-08 US US14/075,919 patent/US20140128452A1/en not_active Abandoned
-
2015
- 2015-05-05 US US14/704,333 patent/US20150290238A1/en not_active Abandoned
-
2016
- 2016-07-21 US US15/216,231 patent/US20170067058A1/en not_active Abandoned
-
2019
- 2019-01-02 US US16/237,875 patent/US20190330637A1/en not_active Abandoned
-
2022
- 2022-06-03 US US17/805,290 patent/US20220340910A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3673910A1 (en) | 2020-07-01 |
| US20140128452A1 (en) | 2014-05-08 |
| JP2011037847A (ja) | 2011-02-24 |
| EP2238987A4 (en) | 2011-11-02 |
| JP5481426B2 (ja) | 2014-04-23 |
| US20190330637A1 (en) | 2019-10-31 |
| EP3045178A1 (en) | 2016-07-20 |
| CN103656644A (zh) | 2014-03-26 |
| WO2009084232A1 (ja) | 2009-07-09 |
| KR101926292B1 (ko) | 2018-12-06 |
| SG10202001748VA (en) | 2020-04-29 |
| US20150290238A1 (en) | 2015-10-15 |
| KR20160007671A (ko) | 2016-01-20 |
| US20220340910A1 (en) | 2022-10-27 |
| EP3360556A1 (en) | 2018-08-15 |
| EP3360556B1 (en) | 2020-04-08 |
| KR20160103554A (ko) | 2016-09-01 |
| US20110027248A1 (en) | 2011-02-03 |
| US20170067058A1 (en) | 2017-03-09 |
| JP4751956B2 (ja) | 2011-08-17 |
| KR20170100064A (ko) | 2017-09-01 |
| KR20180132162A (ko) | 2018-12-11 |
| JP2011162558A (ja) | 2011-08-25 |
| EP3673910B1 (en) | 2023-11-22 |
| SG10201402793PA (en) | 2014-10-30 |
| CN101965196A (zh) | 2011-02-02 |
| JPWO2009084232A1 (ja) | 2011-05-19 |
| KR20190143485A (ko) | 2019-12-30 |
| KR102244872B1 (ko) | 2021-04-27 |
| EP2238987A1 (en) | 2010-10-13 |
| JP4585611B2 (ja) | 2010-11-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20220340910A1 (en) | Sugar chain-related gene and use thereof | |
| JP2008189667A (ja) | 慢性閉塞性肺疾患改善剤 | |
| JP2008273955A (ja) | 炎症性腸疾患改善剤 | |
| JP4147264B2 (ja) | 神経線維性変性抑制剤 | |
| US20090060892A1 (en) | Agents for suppressing hepatic fibrosis | |
| JP2016518812A (ja) | 線維症治療において有用な分子標的及び前記標的のインヒビター | |
| JP2006213621A (ja) | Adoplinタンパク質、およびその利用 | |
| WO2008029868A1 (fr) | Inhibiteur de néovascularisation fibreuse oculaire | |
| HK1195501A (en) | Sugar chain-related gene and use thereof | |
| JPWO2008149980A1 (ja) | 線維化抑制剤 | |
| JP2009292725A (ja) | 腎疾患改善剤 | |
| JP2009234916A (ja) | コンドロイチン硫酸プロテオグリカン蓄積制御に基づくインスリン抵抗性抑制剤 | |
| WO2011140315A2 (en) | Method of reducing proteins misfolding and/or aggregation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20100726 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20131127 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20141128 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20150902 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20141128 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |
|
| J201 | Request for trial against refusal decision | ||
| PJ0201 | Trial against decision of rejection |
Patent event date: 20151203 Comment text: Request for Trial against Decision on Refusal Patent event code: PJ02012R01D Patent event date: 20150902 Comment text: Decision to Refuse Application Patent event code: PJ02011S01I Appeal kind category: Appeal against decision to decline refusal Appeal identifier: 2015101007242 Request date: 20151203 |
|
| A107 | Divisional application of patent | ||
| PA0104 | Divisional application for international application |
Comment text: Divisional Application for International Patent Patent event code: PA01041R01D Patent event date: 20151230 |
|
| J121 | Written withdrawal of request for trial | ||
| PC1202 | Submission of document of withdrawal before decision of registration |
Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment) Patent event code: PC12021R01D Patent event date: 20160104 |
|
| PJ1201 | Withdrawal of trial |
Patent event code: PJ12011R01D Patent event date: 20160104 Comment text: Written Withdrawal of Request for Trial Appeal identifier: 2015101007242 Request date: 20151203 Appeal kind category: Appeal against decision to decline refusal |
|
| WITB | Written withdrawal of application |