KR20100099190A - Ｓｍ-단백질 기반의 분비 조작 - Google Patents

Ｓｍ-단백질 기반의 분비 조작 Download PDF

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Publication number
KR20100099190A
KR20100099190A KR1020107013514A KR20107013514A KR20100099190A KR 20100099190 A KR20100099190 A KR 20100099190A KR 1020107013514 A KR1020107013514 A KR 1020107013514A KR 20107013514 A KR20107013514 A KR 20107013514A KR 20100099190 A KR20100099190 A KR 20100099190A
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KR
South Korea
Prior art keywords
protein
cell
expression
seq
cells
Prior art date
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Ceased
Application number
KR1020107013514A
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English (en)
Korean (ko)
Inventor
히토 카우프만
에릭 베커
로레 플로린
마르틴 푸쎄네거
렌-방 펭
조이 엠. 스터츠
Original Assignee
베링거 잉겔하임 파르마 게엠베하 운트 코 카게
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Publication of KR20100099190A publication Critical patent/KR20100099190A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020107013514A 2007-12-20 2008-12-19 Ｓｍ-단백질 기반의 분비 조작 Ceased KR20100099190A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP07150254.6 2007-12-20
EP07150254 2007-12-20
EP08152829.1 2008-03-17
EP08152829 2008-03-17

Publications (1)

Publication Number Publication Date
KR20100099190A true KR20100099190A (ko) 2010-09-10

Family

ID=40344722

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107013514A Ceased KR20100099190A (ko) 2007-12-20 2008-12-19 Ｓｍ-단백질 기반의 분비 조작

Country Status (14)

Country Link
US (1) US20090247609A1 (https=)
EP (1) EP2225389A1 (https=)
JP (1) JP2011505850A (https=)
KR (1) KR20100099190A (https=)
CN (1) CN101903529A (https=)
AR (1) AR069958A1 (https=)
AU (1) AU2008340652A1 (https=)
BR (1) BRPI0821389A2 (https=)
CA (1) CA2709645A1 (https=)
EA (1) EA201000945A1 (https=)
IL (1) IL205239A0 (https=)
NZ (1) NZ586037A (https=)
TW (1) TW200932907A (https=)
WO (1) WO2009080299A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102575264A (zh) 2009-09-18 2012-07-11 瑟莱克斯公司 增加的转基因表达和加工的产品和方法
TW201823460A (zh) * 2012-05-29 2018-07-01 美商再生元醫藥公司 生產細胞株增強子
FI3536797T3 (fi) 2013-02-01 2023-03-23 Selexis Sa Siirtogeenin tehostettu ilmentäminen ja prosessointi
KR102514666B1 (ko) 2014-12-19 2023-03-27 메르츠 파마 게엠베하 운트 코. 카가아 세포에서 BoNT/E의 생물학적 활성의 결정을 위한 수단 및 방법
CN106554973B (zh) * 2015-09-30 2020-05-22 北京吉尚立德生物科技有限公司 一种cho细胞分泌能力评价系统
US20230051925A1 (en) * 2020-01-20 2023-02-16 Ev Cell Biotech (Guangzhou) Co., Ltd. Vesicle and use thereof
WO2023155881A1 (en) * 2022-02-18 2023-08-24 Tsinghua University Methods for regulating secretion via migrasomes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI924494A0 (fi) * 1992-10-06 1992-10-06 Valtion Teknillinen Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller
JP2001512684A (ja) * 1997-08-05 2001-08-28 カイロン コーポレイション 新規のｐｉｃｈｉａｐａｓｔｏｒｉｓ遺伝子配列およびそれらの使用方法
AU2002952550A0 (en) * 2002-11-08 2002-11-21 The University Of Queensland Modulating TNFalpha Secretion

Also Published As

Publication number Publication date
US20090247609A1 (en) 2009-10-01
IL205239A0 (en) 2010-11-30
CN101903529A (zh) 2010-12-01
AR069958A1 (es) 2010-03-03
CA2709645A1 (en) 2009-07-02
WO2009080299A1 (en) 2009-07-02
TW200932907A (en) 2009-08-01
EP2225389A1 (en) 2010-09-08
AU2008340652A1 (en) 2009-07-02
EA201000945A1 (ru) 2011-02-28
WO2009080299A8 (en) 2010-04-15
NZ586037A (en) 2012-08-31
JP2011505850A (ja) 2011-03-03
BRPI0821389A2 (pt) 2015-06-16

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