KR20100089077A - 혈전용해를 위한 신규한 환자 소집단 - Google Patents

혈전용해를 위한 신규한 환자 소집단 Download PDF

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Publication number
KR20100089077A
KR20100089077A KR1020107010609A KR20107010609A KR20100089077A KR 20100089077 A KR20100089077 A KR 20100089077A KR 1020107010609 A KR1020107010609 A KR 1020107010609A KR 20107010609 A KR20107010609 A KR 20107010609A KR 20100089077 A KR20100089077 A KR 20100089077A
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KR
South Korea
Prior art keywords
use according
stroke
plasminogen activator
patient
patients
Prior art date
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Ceased
Application number
KR1020107010609A
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English (en)
Korean (ko)
Inventor
마리올라 죈겐
알리스 에벨
야시르 알라 샤픽 알-라위
Original Assignee
파이온 도이치란트 게엠베하
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40567844&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20100089077(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP07020401A external-priority patent/EP2050462A1/en
Application filed by 파이온 도이치란트 게엠베하 filed Critical 파이온 도이치란트 게엠베하
Publication of KR20100089077A publication Critical patent/KR20100089077A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49Urokinase; Tissue plasminogen activator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
KR1020107010609A 2007-10-18 2008-10-20 혈전용해를 위한 신규한 환자 소집단 Ceased KR20100089077A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP07020401.1 2007-10-18
EP07020401A EP2050462A1 (en) 2007-10-18 2007-10-18 Improved treatment of stroke patients
EP07022867.1 2007-11-26
EP07022867 2007-11-26
EP08017954 2008-10-15
EP08017954.2 2008-10-15

Publications (1)

Publication Number Publication Date
KR20100089077A true KR20100089077A (ko) 2010-08-11

Family

ID=40567844

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107010609A Ceased KR20100089077A (ko) 2007-10-18 2008-10-20 혈전용해를 위한 신규한 환자 소집단

Country Status (28)

Country Link
US (2) US20100272704A1 (enExample)
EP (1) EP2211898B1 (enExample)
JP (2) JP5509085B2 (enExample)
KR (1) KR20100089077A (enExample)
CN (1) CN101903039B (enExample)
AR (1) AR068914A1 (enExample)
AU (1) AU2008314048B2 (enExample)
BR (1) BRPI0817785A2 (enExample)
CA (1) CA2702378A1 (enExample)
CL (1) CL2009000752A1 (enExample)
CY (1) CY1118417T1 (enExample)
DK (1) DK2211898T3 (enExample)
EA (1) EA020776B1 (enExample)
ES (1) ES2611155T3 (enExample)
HR (1) HRP20170001T1 (enExample)
HU (1) HUE032867T2 (enExample)
IL (1) IL205175A0 (enExample)
LT (1) LT2211898T (enExample)
MX (1) MX2010004157A (enExample)
MY (1) MY159200A (enExample)
NZ (1) NZ584640A (enExample)
PL (1) PL2211898T3 (enExample)
PT (1) PT2211898T (enExample)
RS (1) RS55590B1 (enExample)
SI (1) SI2211898T1 (enExample)
TW (1) TWI482628B (enExample)
WO (1) WO2009049914A2 (enExample)
ZA (1) ZA201002548B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10153601A1 (de) 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766075A (en) * 1982-07-14 1988-08-23 Genentech, Inc. Human tissue plasminogen activator
US5244806A (en) * 1985-08-26 1993-09-14 Eli Lilly And Company DNA encoding novel tissue plasminogen activator derivatives having kringles 1 and 2 deleted, vectors and host cells
IL87276A (en) * 1987-08-03 1995-07-31 Fujisawa Pharmaceutical Co Analog of tissue plasminogen activator comprising only the kringle 2 and protease domain dna encoding the same processes for the preparation thereof and pharmaceutical compositions containing the same
US5094953A (en) * 1988-03-21 1992-03-10 Genentech, Inc. Human tissue plasminogen activator variants
FI100403B (fi) * 1988-07-20 1997-11-28 Schering Ag Menetelmä glykosyloitujen tai glykosyloimattomien vampyyrilepakon sylj en plasminogeeniaktivaattoreiden valmistamiseksi
US5714145A (en) * 1988-09-02 1998-02-03 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
US5676947A (en) * 1989-02-07 1997-10-14 Boehringer Manneheim Gmbh Method for treating thromboembolic conditions using thrombolytically active proteins
DE3903581A1 (de) * 1989-02-07 1990-08-16 Boehringer Mannheim Gmbh Gewebs-plasminogenaktivator-derivat
US6008019A (en) * 1989-02-13 1999-12-28 Schering Aktiengesellschaft Plasminogen activator from saliva of the vampire bat
US5891664A (en) * 1989-04-07 1999-04-06 Cancerforskningsfondet Af 1989 Vectors and methods for recombinant production of uPA-binding fragments of the human urokinase-type plasminogen receptor (uPAR)
US5326700A (en) * 1990-11-06 1994-07-05 Eli Lilly And Company DNA sequences encoding t-PA derivatives with cleavable sites
DK0580685T3 (da) * 1991-04-16 1996-03-04 Boehringer Mannheim Gmbh Farmaceutisk emballageenhed indeholdende plasminogenaktivatorer til flerfoldig bolusindgift
US5595736A (en) * 1991-04-22 1997-01-21 Eli Lilly And Company Compounds and methods for treatment of thromboembolic disorders
RU2183214C2 (ru) * 1992-12-04 2002-06-10 Шеринг Аг Природный и рекомбинантный ингибиторы тромбина, их получение и применение
US5510330A (en) * 1994-03-25 1996-04-23 Boehringer Mannheim Gmbh Combinations of thrombolytically active proteins and non-heparin anticoagulants, and uses thereof.
GB9412131D0 (en) * 1994-06-17 1994-08-10 British Bio Technology Thrombolytic composition
US5827832A (en) * 1995-03-06 1998-10-27 Interneuron Pharmaceuticals, Inc. Method of protecting brain tissue from cerebral infarction subsequent to ischemia
US5786187A (en) * 1995-09-21 1998-07-28 The Research Foundation Of State University Of New York Method for reducing neuronal degeneration associated with seizure
US5945432A (en) * 1995-12-22 1999-08-31 The University Of Vermont And State Agricultural College Thrombolytic agents and thienopyridine derivatives in acute stroke
US20020081294A1 (en) * 1996-01-23 2002-06-27 Genentech, Inc. Co-administration of a thrombolytic and an anti-CD18 antibody in stroke
US5731186A (en) * 1996-02-05 1998-03-24 Schering Aktiengesellschaft Method for the production of rDSPA α1
US6354999B1 (en) * 2000-01-14 2002-03-12 Florence Medical Ltd. System and method for detecting, localizing, and characterizing occlusions and aneurysms in a vessel
GB0025473D0 (en) * 2000-10-17 2000-11-29 Pfizer Ltd Pharmaceutical combinations
DE10153601A1 (de) * 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall
US20060135425A1 (en) * 2003-05-02 2006-06-22 Paion Deutschland Gmbh Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke
US20080057050A1 (en) * 2003-05-02 2008-03-06 Paion Deutschland Gmbh Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke
KR20060015721A (ko) * 2003-05-05 2006-02-20 파이온 도이치란트 게엠베하 신경보호제로서의 글루타메이트 수용체 길항제
US20050085478A1 (en) * 2003-08-22 2005-04-21 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a low-molecular-weight heparin for the treatment of central nervous system damage
WO2007025219A2 (en) * 2005-08-25 2007-03-01 Biogen Idec Ma Inc. Nogo receptor polypeptides and polypeptide fragments and uses thereof

Also Published As

Publication number Publication date
CL2009000752A1 (es) 2009-12-04
HK1151233A1 (en) 2012-01-27
RS55590B1 (sr) 2017-06-30
HUE032867T2 (en) 2017-11-28
JP2014065739A (ja) 2014-04-17
US20140314736A1 (en) 2014-10-23
AU2008314048B2 (en) 2013-07-25
CA2702378A1 (en) 2009-04-23
MX2010004157A (es) 2010-04-30
JP5509085B2 (ja) 2014-06-04
EA201070485A1 (ru) 2010-10-29
AU2008314048A1 (en) 2009-04-23
EA020776B1 (ru) 2015-01-30
ES2611155T3 (es) 2017-05-05
JP2011500617A (ja) 2011-01-06
TWI482628B (zh) 2015-05-01
HRP20170001T1 (hr) 2017-02-24
PL2211898T3 (pl) 2017-03-31
SI2211898T1 (sl) 2017-02-28
ZA201002548B (en) 2011-06-29
CN101903039A (zh) 2010-12-01
MY159200A (en) 2016-12-30
LT2211898T (lt) 2017-01-25
DK2211898T3 (en) 2017-01-30
WO2009049914A2 (en) 2009-04-23
AR068914A1 (es) 2009-12-16
EP2211898B1 (en) 2016-12-07
BRPI0817785A2 (pt) 2015-03-24
NZ584640A (en) 2012-10-26
WO2009049914A3 (en) 2009-08-06
CY1118417T1 (el) 2017-06-28
IL205175A0 (en) 2010-11-30
PT2211898T (pt) 2017-01-31
US20100272704A1 (en) 2010-10-28
TW200927164A (en) 2009-07-01
EP2211898A2 (en) 2010-08-04
CN101903039B (zh) 2014-04-02

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