JP5509085B2 - 血栓溶解についての新規な患者亜群 - Google Patents
血栓溶解についての新規な患者亜群 Download PDFInfo
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- JP5509085B2 JP5509085B2 JP2010529300A JP2010529300A JP5509085B2 JP 5509085 B2 JP5509085 B2 JP 5509085B2 JP 2010529300 A JP2010529300 A JP 2010529300A JP 2010529300 A JP2010529300 A JP 2010529300A JP 5509085 B2 JP5509085 B2 JP 5509085B2
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- stroke
- occlusion
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
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- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Electrotherapy Devices (AREA)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07020401.1 | 2007-10-18 | ||
| EP07020401A EP2050462A1 (en) | 2007-10-18 | 2007-10-18 | Improved treatment of stroke patients |
| EP07022867.1 | 2007-11-26 | ||
| EP07022867 | 2007-11-26 | ||
| EP08017954 | 2008-10-15 | ||
| EP08017954.2 | 2008-10-15 | ||
| PCT/EP2008/008871 WO2009049914A2 (en) | 2007-10-18 | 2008-10-20 | Novel patient subgroups for thrombolysis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014000825A Division JP2014065739A (ja) | 2007-10-18 | 2014-01-07 | 血栓溶解についての新規な患者亜群 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011500617A JP2011500617A (ja) | 2011-01-06 |
| JP2011500617A5 JP2011500617A5 (enExample) | 2012-08-16 |
| JP5509085B2 true JP5509085B2 (ja) | 2014-06-04 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010529300A Expired - Fee Related JP5509085B2 (ja) | 2007-10-18 | 2008-10-20 | 血栓溶解についての新規な患者亜群 |
| JP2014000825A Withdrawn JP2014065739A (ja) | 2007-10-18 | 2014-01-07 | 血栓溶解についての新規な患者亜群 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014000825A Withdrawn JP2014065739A (ja) | 2007-10-18 | 2014-01-07 | 血栓溶解についての新規な患者亜群 |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US20100272704A1 (enExample) |
| EP (1) | EP2211898B1 (enExample) |
| JP (2) | JP5509085B2 (enExample) |
| KR (1) | KR20100089077A (enExample) |
| CN (1) | CN101903039B (enExample) |
| AR (1) | AR068914A1 (enExample) |
| AU (1) | AU2008314048B2 (enExample) |
| BR (1) | BRPI0817785A2 (enExample) |
| CA (1) | CA2702378A1 (enExample) |
| CL (1) | CL2009000752A1 (enExample) |
| CY (1) | CY1118417T1 (enExample) |
| DK (1) | DK2211898T3 (enExample) |
| EA (1) | EA020776B1 (enExample) |
| ES (1) | ES2611155T3 (enExample) |
| HR (1) | HRP20170001T1 (enExample) |
| HU (1) | HUE032867T2 (enExample) |
| IL (1) | IL205175A0 (enExample) |
| LT (1) | LT2211898T (enExample) |
| MX (1) | MX2010004157A (enExample) |
| MY (1) | MY159200A (enExample) |
| NZ (1) | NZ584640A (enExample) |
| PL (1) | PL2211898T3 (enExample) |
| PT (1) | PT2211898T (enExample) |
| RS (1) | RS55590B1 (enExample) |
| SI (1) | SI2211898T1 (enExample) |
| TW (1) | TWI482628B (enExample) |
| WO (1) | WO2009049914A2 (enExample) |
| ZA (1) | ZA201002548B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10153601A1 (de) | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA zur Behandlung von Schlaganfall |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4766075A (en) * | 1982-07-14 | 1988-08-23 | Genentech, Inc. | Human tissue plasminogen activator |
| US5244806A (en) * | 1985-08-26 | 1993-09-14 | Eli Lilly And Company | DNA encoding novel tissue plasminogen activator derivatives having kringles 1 and 2 deleted, vectors and host cells |
| IL87276A (en) * | 1987-08-03 | 1995-07-31 | Fujisawa Pharmaceutical Co | Analog of tissue plasminogen activator comprising only the kringle 2 and protease domain dna encoding the same processes for the preparation thereof and pharmaceutical compositions containing the same |
| US5094953A (en) * | 1988-03-21 | 1992-03-10 | Genentech, Inc. | Human tissue plasminogen activator variants |
| FI100403B (fi) * | 1988-07-20 | 1997-11-28 | Schering Ag | Menetelmä glykosyloitujen tai glykosyloimattomien vampyyrilepakon sylj en plasminogeeniaktivaattoreiden valmistamiseksi |
| US5714145A (en) * | 1988-09-02 | 1998-02-03 | Genentech, Inc. | Tissue plasminogen activator having zymogenic or fibrin specific properties |
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