JP2011500617A5 - - Google Patents

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Publication number
JP2011500617A5
JP2011500617A5 JP2010529300A JP2010529300A JP2011500617A5 JP 2011500617 A5 JP2011500617 A5 JP 2011500617A5 JP 2010529300 A JP2010529300 A JP 2010529300A JP 2010529300 A JP2010529300 A JP 2010529300A JP 2011500617 A5 JP2011500617 A5 JP 2011500617A5
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JP
Japan
Prior art keywords
composition
plasminogen activator
stroke
patient
patients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010529300A
Other languages
English (en)
Japanese (ja)
Other versions
JP5509085B2 (ja
JP2011500617A (ja
Filing date
Publication date
Priority claimed from EP07020401A external-priority patent/EP2050462A1/en
Application filed filed Critical
Priority claimed from PCT/EP2008/008871 external-priority patent/WO2009049914A2/en
Publication of JP2011500617A publication Critical patent/JP2011500617A/ja
Publication of JP2011500617A5 publication Critical patent/JP2011500617A5/ja
Application granted granted Critical
Publication of JP5509085B2 publication Critical patent/JP5509085B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010529300A 2007-10-18 2008-10-20 血栓溶解についての新規な患者亜群 Expired - Fee Related JP5509085B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP07020401.1 2007-10-18
EP07020401A EP2050462A1 (en) 2007-10-18 2007-10-18 Improved treatment of stroke patients
EP07022867.1 2007-11-26
EP07022867 2007-11-26
EP08017954 2008-10-15
EP08017954.2 2008-10-15
PCT/EP2008/008871 WO2009049914A2 (en) 2007-10-18 2008-10-20 Novel patient subgroups for thrombolysis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014000825A Division JP2014065739A (ja) 2007-10-18 2014-01-07 血栓溶解についての新規な患者亜群

Publications (3)

Publication Number Publication Date
JP2011500617A JP2011500617A (ja) 2011-01-06
JP2011500617A5 true JP2011500617A5 (enExample) 2012-08-16
JP5509085B2 JP5509085B2 (ja) 2014-06-04

Family

ID=40567844

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010529300A Expired - Fee Related JP5509085B2 (ja) 2007-10-18 2008-10-20 血栓溶解についての新規な患者亜群
JP2014000825A Withdrawn JP2014065739A (ja) 2007-10-18 2014-01-07 血栓溶解についての新規な患者亜群

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014000825A Withdrawn JP2014065739A (ja) 2007-10-18 2014-01-07 血栓溶解についての新規な患者亜群

Country Status (28)

Country Link
US (2) US20100272704A1 (enExample)
EP (1) EP2211898B1 (enExample)
JP (2) JP5509085B2 (enExample)
KR (1) KR20100089077A (enExample)
CN (1) CN101903039B (enExample)
AR (1) AR068914A1 (enExample)
AU (1) AU2008314048B2 (enExample)
BR (1) BRPI0817785A2 (enExample)
CA (1) CA2702378A1 (enExample)
CL (1) CL2009000752A1 (enExample)
CY (1) CY1118417T1 (enExample)
DK (1) DK2211898T3 (enExample)
EA (1) EA020776B1 (enExample)
ES (1) ES2611155T3 (enExample)
HR (1) HRP20170001T1 (enExample)
HU (1) HUE032867T2 (enExample)
IL (1) IL205175A0 (enExample)
LT (1) LT2211898T (enExample)
MX (1) MX2010004157A (enExample)
MY (1) MY159200A (enExample)
NZ (1) NZ584640A (enExample)
PL (1) PL2211898T3 (enExample)
PT (1) PT2211898T (enExample)
RS (1) RS55590B1 (enExample)
SI (1) SI2211898T1 (enExample)
TW (1) TWI482628B (enExample)
WO (1) WO2009049914A2 (enExample)
ZA (1) ZA201002548B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10153601A1 (de) 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766075A (en) * 1982-07-14 1988-08-23 Genentech, Inc. Human tissue plasminogen activator
US5244806A (en) * 1985-08-26 1993-09-14 Eli Lilly And Company DNA encoding novel tissue plasminogen activator derivatives having kringles 1 and 2 deleted, vectors and host cells
IL87276A (en) * 1987-08-03 1995-07-31 Fujisawa Pharmaceutical Co Analog of tissue plasminogen activator comprising only the kringle 2 and protease domain dna encoding the same processes for the preparation thereof and pharmaceutical compositions containing the same
US5094953A (en) * 1988-03-21 1992-03-10 Genentech, Inc. Human tissue plasminogen activator variants
FI100403B (fi) * 1988-07-20 1997-11-28 Schering Ag Menetelmä glykosyloitujen tai glykosyloimattomien vampyyrilepakon sylj en plasminogeeniaktivaattoreiden valmistamiseksi
US5714145A (en) * 1988-09-02 1998-02-03 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
US5676947A (en) * 1989-02-07 1997-10-14 Boehringer Manneheim Gmbh Method for treating thromboembolic conditions using thrombolytically active proteins
DE3903581A1 (de) * 1989-02-07 1990-08-16 Boehringer Mannheim Gmbh Gewebs-plasminogenaktivator-derivat
US6008019A (en) * 1989-02-13 1999-12-28 Schering Aktiengesellschaft Plasminogen activator from saliva of the vampire bat
US5891664A (en) * 1989-04-07 1999-04-06 Cancerforskningsfondet Af 1989 Vectors and methods for recombinant production of uPA-binding fragments of the human urokinase-type plasminogen receptor (uPAR)
US5326700A (en) * 1990-11-06 1994-07-05 Eli Lilly And Company DNA sequences encoding t-PA derivatives with cleavable sites
DK0580685T3 (da) * 1991-04-16 1996-03-04 Boehringer Mannheim Gmbh Farmaceutisk emballageenhed indeholdende plasminogenaktivatorer til flerfoldig bolusindgift
US5595736A (en) * 1991-04-22 1997-01-21 Eli Lilly And Company Compounds and methods for treatment of thromboembolic disorders
RU2183214C2 (ru) * 1992-12-04 2002-06-10 Шеринг Аг Природный и рекомбинантный ингибиторы тромбина, их получение и применение
US5510330A (en) * 1994-03-25 1996-04-23 Boehringer Mannheim Gmbh Combinations of thrombolytically active proteins and non-heparin anticoagulants, and uses thereof.
GB9412131D0 (en) * 1994-06-17 1994-08-10 British Bio Technology Thrombolytic composition
US5827832A (en) * 1995-03-06 1998-10-27 Interneuron Pharmaceuticals, Inc. Method of protecting brain tissue from cerebral infarction subsequent to ischemia
US5786187A (en) * 1995-09-21 1998-07-28 The Research Foundation Of State University Of New York Method for reducing neuronal degeneration associated with seizure
US5945432A (en) * 1995-12-22 1999-08-31 The University Of Vermont And State Agricultural College Thrombolytic agents and thienopyridine derivatives in acute stroke
US20020081294A1 (en) * 1996-01-23 2002-06-27 Genentech, Inc. Co-administration of a thrombolytic and an anti-CD18 antibody in stroke
US5731186A (en) * 1996-02-05 1998-03-24 Schering Aktiengesellschaft Method for the production of rDSPA α1
US6354999B1 (en) * 2000-01-14 2002-03-12 Florence Medical Ltd. System and method for detecting, localizing, and characterizing occlusions and aneurysms in a vessel
GB0025473D0 (en) * 2000-10-17 2000-11-29 Pfizer Ltd Pharmaceutical combinations
DE10153601A1 (de) * 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall
US20060135425A1 (en) * 2003-05-02 2006-06-22 Paion Deutschland Gmbh Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke
US20080057050A1 (en) * 2003-05-02 2008-03-06 Paion Deutschland Gmbh Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke
KR20060015721A (ko) * 2003-05-05 2006-02-20 파이온 도이치란트 게엠베하 신경보호제로서의 글루타메이트 수용체 길항제
US20050085478A1 (en) * 2003-08-22 2005-04-21 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a low-molecular-weight heparin for the treatment of central nervous system damage
WO2007025219A2 (en) * 2005-08-25 2007-03-01 Biogen Idec Ma Inc. Nogo receptor polypeptides and polypeptide fragments and uses thereof

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