KR20090042971A - 항미생물 활성을 갖는 신규한 마크로라이드 및 케토라이드 - Google Patents

항미생물 활성을 갖는 신규한 마크로라이드 및 케토라이드 Download PDF

Info

Publication number
KR20090042971A
KR20090042971A KR1020097005432A KR20097005432A KR20090042971A KR 20090042971 A KR20090042971 A KR 20090042971A KR 1020097005432 A KR1020097005432 A KR 1020097005432A KR 20097005432 A KR20097005432 A KR 20097005432A KR 20090042971 A KR20090042971 A KR 20090042971A
Authority
KR
South Korea
Prior art keywords
formula
compound
phenyl
substituted
pyridin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020097005432A
Other languages
English (en)
Korean (ko)
Inventor
밀린드 다타트라야 신드케드카르
비자야 나라얀 데사이
라제시 마간랄 로리야
마헤시 비트할브하이 파텔
브하라트 칼리다스 트리베디
라제시 온카르다스 보라
산토시 데비다스 디와카르
가네시 라자람 자드하브
시바지 삼파트라오 파와르
Original Assignee
욱크하르트 리서치 센터
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 욱크하르트 리서치 센터 filed Critical 욱크하르트 리서치 센터
Publication of KR20090042971A publication Critical patent/KR20090042971A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
KR1020097005432A 2006-08-24 2007-08-22 항미생물 활성을 갖는 신규한 마크로라이드 및 케토라이드 Ceased KR20090042971A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1336MU2006 2006-08-24
IN1336/MUM/2006 2006-08-24

Publications (1)

Publication Number Publication Date
KR20090042971A true KR20090042971A (ko) 2009-05-04

Family

ID=39107171

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097005432A Ceased KR20090042971A (ko) 2006-08-24 2007-08-22 항미생물 활성을 갖는 신규한 마크로라이드 및 케토라이드

Country Status (7)

Country Link
US (1) US8097594B2 (https=)
EP (1) EP2056844A4 (https=)
JP (1) JP2010501541A (https=)
KR (1) KR20090042971A (https=)
CN (1) CN101541331A (https=)
CA (1) CA2661538A1 (https=)
WO (1) WO2008023248A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101669432B1 (ko) 2007-08-27 2016-10-26 다트 뉴로사이언스 (케이만) 엘티디. 치료적 이속사졸 화합물
CN101910159B (zh) * 2007-12-26 2013-06-19 卫材R&D管理有限公司 杂环取代吡啶衍生物的制备方法
ES2561332T3 (es) 2009-05-27 2016-02-25 Wockhardt Limited Compuestos cetólidos que tienen actividad antimicrobiana
PT2673285T (pt) 2010-12-09 2017-10-19 Wockhardt Ltd Resumo
JP5718488B2 (ja) * 2011-03-01 2015-05-13 ウォックハート リミテッド ケトライド中間体の調製方法
WO2012127351A1 (en) * 2011-03-22 2012-09-27 Wockhardt Limited Process for preparation of ketolide compounds
WO2012129564A2 (en) 2011-03-24 2012-09-27 H. Lee Moffitt Cancer Center And Research Institute, Inc. Proteasome chymotrypsin-like inhibition using pi-1833 analogs
CN102260225B (zh) * 2011-06-02 2013-08-21 蒋杰 用于抑制肿瘤转移和肿瘤血管生长的苯基哌嗪类衍生物
CN106998685A (zh) * 2014-10-08 2017-08-01 哈佛大学的校长及成员们 14‑元酮内酯及其制备和使用方法
KR20190129863A (ko) * 2017-03-16 2019-11-20 욱크하르트 리미티드 케톨라이드 화합물의 제조 방법
ES2948122A1 (es) * 2022-02-10 2023-08-31 Fundacion Instituto De Investig Sanitaria Aragon Compuestos para el tratamiento y/o prevención de una infección o enfermedad causada por Helicobacter o Campylobacter

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473525A1 (fr) 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
US4331803A (en) 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
SI8110592A8 (en) 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
FR2719587B1 (fr) 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
DE69733422T2 (de) 1996-09-04 2006-05-04 Abbott Laboratories, Abbott Park 6-0-substituierte ketoliden mit antibakteriellen wirkung
JP4162992B2 (ja) * 2000-08-22 2008-10-08 バジリア ファルマスーチカ アーゲー 抗菌活性を有する新規マクロライド
US20040077557A1 (en) * 2000-12-21 2004-04-22 Sulejman Ali Macrolide antibiotics
GB0031312D0 (en) 2000-12-21 2001-02-07 Glaxo Group Ltd Macrolides
EP1406898B1 (en) 2001-07-19 2005-04-06 Cv Therapeutics, Inc. Substituted piperazine compounds and their use as fatty acid oxidation inhibitors
GB0127349D0 (en) 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
US6995143B2 (en) 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
US6727229B2 (en) 2002-08-19 2004-04-27 Enanta Pharmaceuticals, Inc. 11,12-substituted lactone ketolide derivatives having antibacterial activity
JP5112079B2 (ja) * 2005-02-09 2013-01-09 バジリア ファルマスーチカ アーゲー 新規なマクロライド

Also Published As

Publication number Publication date
EP2056844A4 (en) 2010-11-24
US8097594B2 (en) 2012-01-17
WO2008023248A2 (en) 2008-02-28
CA2661538A1 (en) 2008-02-28
US20090247478A1 (en) 2009-10-01
EP2056844A2 (en) 2009-05-13
CN101541331A (zh) 2009-09-23
JP2010501541A (ja) 2010-01-21
WO2008023248A3 (en) 2009-04-23

Similar Documents

Publication Publication Date Title
KR20090042971A (ko) 항미생물 활성을 갖는 신규한 마크로라이드 및 케토라이드
RU2601550C2 (ru) Кетолидные соединения
JP2010501541A5 (https=)
KR20190046894A (ko) 항생제 화합물
KR101566053B1 (ko) 항균 활성을 갖는 케톨라이드
BG63207B1 (bg) Нови производни на еритромицин, метод за тяхното получаване и използването им като лекарствено средство
AU2019382504A1 (en) Cyclic ureas
KR100587445B1 (ko) 에리트로마이신의 신규한 유도체, 그의 제조 방법 및약제로서의 그의 용도
KR19990067492A (ko) 트리사이클릭 에리트로마이신 유도체
KR20130132626A (ko) 케톨리드 중간체의 제조 방법
EA011281B1 (ru) Макролиды
KR101223158B1 (ko) 6,11-다리걸친 바이아릴 매크로라이드
CZ20013223A3 (cs) 6-0-Substituované makrolidy mající antibakteriální aktivitu
JP7112963B2 (ja) セコマクロライド化合物
AP997A (en) Novel erythromycin derivatives, method for preparing them and their use as medicine.
EP1323726A1 (en) Erythromycin derivatives and medicines containing the same
JP2000351793A (ja) エリスロマイシン誘導体
CN100526325C (zh) 大环内酯类药物红霉素a衍生物、合成方法和用途
TW201350498A (zh) 治療細菌感染之甘露糖衍生物
JP2003073394A (ja) エリスロマイシン誘導体
NZ611653A (en) Ketolide compounds
JP2014177404A (ja) 核酸抗生物質誘導体
NZ611653B (en) Ketolide compounds

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20090316

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20111027

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20121220

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20130626

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20121220

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I