KR20090042971A - 항미생물 활성을 갖는 신규한 마크로라이드 및 케토라이드 - Google Patents

항미생물 활성을 갖는 신규한 마크로라이드 및 케토라이드 Download PDF

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Publication number
KR20090042971A
KR20090042971A KR1020097005432A KR20097005432A KR20090042971A KR 20090042971 A KR20090042971 A KR 20090042971A KR 1020097005432 A KR1020097005432 A KR 1020097005432A KR 20097005432 A KR20097005432 A KR 20097005432A KR 20090042971 A KR20090042971 A KR 20090042971A
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KR
South Korea
Prior art keywords
formula
compound
phenyl
substituted
pyridin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020097005432A
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English (en)
Korean (ko)
Inventor
밀린드 다타트라야 신드케드카르
비자야 나라얀 데사이
라제시 마간랄 로리야
마헤시 비트할브하이 파텔
브하라트 칼리다스 트리베디
라제시 온카르다스 보라
산토시 데비다스 디와카르
가네시 라자람 자드하브
시바지 삼파트라오 파와르
Original Assignee
욱크하르트 리서치 센터
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 욱크하르트 리서치 센터 filed Critical 욱크하르트 리서치 센터
Publication of KR20090042971A publication Critical patent/KR20090042971A/ko
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
KR1020097005432A 2006-08-24 2007-08-22 항미생물 활성을 갖는 신규한 마크로라이드 및 케토라이드 Ceased KR20090042971A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1336/MUM/2006 2006-08-24
IN1336MU2006 2006-08-24

Publications (1)

Publication Number Publication Date
KR20090042971A true KR20090042971A (ko) 2009-05-04

Family

ID=39107171

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097005432A Ceased KR20090042971A (ko) 2006-08-24 2007-08-22 항미생물 활성을 갖는 신규한 마크로라이드 및 케토라이드

Country Status (7)

Country Link
US (1) US8097594B2 (cg-RX-API-DMAC10.html)
EP (1) EP2056844A4 (cg-RX-API-DMAC10.html)
JP (1) JP2010501541A (cg-RX-API-DMAC10.html)
KR (1) KR20090042971A (cg-RX-API-DMAC10.html)
CN (1) CN101541331A (cg-RX-API-DMAC10.html)
CA (1) CA2661538A1 (cg-RX-API-DMAC10.html)
WO (1) WO2008023248A2 (cg-RX-API-DMAC10.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8222243B2 (en) 2007-08-27 2012-07-17 Dart Neuroscience (Cayman) Ltd Therapeutic isoxazole compounds
WO2009081970A1 (ja) * 2007-12-26 2009-07-02 Eisai R & D Management Co., Ltd. ヘテロ環置換ピリジン誘導体の製造方法
EP2435460B1 (en) * 2009-05-27 2015-01-07 Wockhardt Limited Ketolide compounds having antimicrobial activity
RU2601550C2 (ru) 2010-12-09 2016-11-10 Вокхардт Лимитед Кетолидные соединения
CN103619849B (zh) * 2011-03-01 2016-05-25 沃克哈特有限公司 酮内酯中间体的制备方法
EP2688900B1 (en) * 2011-03-22 2016-09-28 Wockhardt Limited Process for preparation of ketolide compounds
WO2012129564A2 (en) 2011-03-24 2012-09-27 H. Lee Moffitt Cancer Center And Research Institute, Inc. Proteasome chymotrypsin-like inhibition using pi-1833 analogs
CN102260225B (zh) * 2011-06-02 2013-08-21 蒋杰 用于抑制肿瘤转移和肿瘤血管生长的苯基哌嗪类衍生物
JP2017531663A (ja) * 2014-10-08 2017-10-26 プレジデント アンド フェローズ オブ ハーバード カレッジ １４員ケトライドならびにそれらの調製および使用の方法
KR20190129863A (ko) * 2017-03-16 2019-11-20 욱크하르트 리미티드 케톨라이드 화합물의 제조 방법
ES2948122A1 (es) * 2022-02-10 2023-08-31 Fundacion Instituto De Investig Sanitaria Aragon Compuestos para el tratamiento y/o prevención de una infección o enfermedad causada por Helicobacter o Campylobacter

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473525A1 (fr) 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
US4331803A (en) 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
YU43006B (en) 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
FR2719587B1 (fr) 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
DE69733439T2 (de) 1996-09-04 2006-05-04 Abbott Laboratories, Abbott Park 6-o-Substituierte Ketoliden mit antibakteriellen Wirkung
MXPA03001607A (es) 2000-08-22 2003-06-04 Basilea Pharmaceutica Ag Nuevos macrolidos con actividad antibacteriana.
JP2004531471A (ja) * 2000-12-21 2004-10-14 グラクソ　グループ　リミテッド マクロライド抗生物質
GB0031312D0 (en) 2000-12-21 2001-02-07 Glaxo Group Ltd Macrolides
MXPA04000565A (es) 2001-07-19 2005-06-17 Cv Therapeutics Inc Compuestos de piperazina sustituidos y su uso como inhibidores de oxidacion de acidos grasos.
GB0127349D0 (en) 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
US6995143B2 (en) 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
US6727229B2 (en) 2002-08-19 2004-04-27 Enanta Pharmaceuticals, Inc. 11,12-substituted lactone ketolide derivatives having antibacterial activity
HRP20090302T1 (hr) * 2005-02-09 2009-07-31 Basilea Pharmaceutica Ag Novi makrolidi

Also Published As

Publication number Publication date
US8097594B2 (en) 2012-01-17
WO2008023248A2 (en) 2008-02-28
CA2661538A1 (en) 2008-02-28
WO2008023248A3 (en) 2009-04-23
EP2056844A4 (en) 2010-11-24
US20090247478A1 (en) 2009-10-01
CN101541331A (zh) 2009-09-23
JP2010501541A (ja) 2010-01-21
EP2056844A2 (en) 2009-05-13

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Patent event date: 20090316

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