KR20090034998A - 알레르기성 질환과 같은 비만세포계 질병에 대한 ｎ-페닐-2-피리미딘아민의 용도 - Google Patents

알레르기성 질환과 같은 비만세포계 질병에 대한 ｎ-페닐-2-피리미딘아민의 용도 Download PDF

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Publication number
KR20090034998A
KR20090034998A KR1020097003644A KR20097003644A KR20090034998A KR 20090034998 A KR20090034998 A KR 20090034998A KR 1020097003644 A KR1020097003644 A KR 1020097003644A KR 20097003644 A KR20097003644 A KR 20097003644A KR 20090034998 A KR20090034998 A KR 20090034998A
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KR
South Korea
Prior art keywords
cells
phenyl
compound
mast cell
methyl
Prior art date
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KR1020097003644A
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English (en)
Korean (ko)
Inventor
겐이찌 고이께
아쯔시 고미야마
고이찌 다께우찌
마이클 헤인리치
모또오 나까지마
Original Assignee
노파르티스 아게
더 거번먼트 오브 더 유나이티드 스테이츠 디파트먼트 오브베테랑스 어페어스
겐이찌 고이께
오레곤 헬스 앤드 사이언스 유니버시티
아쯔시 고미야마
고이찌 다께우찌
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 노파르티스 아게, 더 거번먼트 오브 더 유나이티드 스테이츠 디파트먼트 오브베테랑스 어페어스, 겐이찌 고이께, 오레곤 헬스 앤드 사이언스 유니버시티, 아쯔시 고미야마, 고이찌 다께우찌 filed Critical 노파르티스 아게
Publication of KR20090034998A publication Critical patent/KR20090034998A/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
KR1020097003644A 2001-04-05 2002-04-05 알레르기성 질환과 같은 비만세포계 질병에 대한 ｎ-페닐-2-피리미딘아민의 용도 KR20090034998A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0108606.5A GB0108606D0 (en) 2001-04-05 2001-04-05 Organic compounds
GB0108606.5 2001-04-05

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR10-2003-7012939A Division KR20040007485A (ko) 2001-04-05 2002-04-05 알레르기성 질환과 같은 비만세포계 질병에 대한ｎ-페닐-2-피리미딘아민의 용도

Publications (1)

Publication Number Publication Date
KR20090034998A true KR20090034998A (ko) 2009-04-08

Family

ID=9912339

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020097003644A KR20090034998A (ko) 2001-04-05 2002-04-05 알레르기성 질환과 같은 비만세포계 질병에 대한 ｎ-페닐-2-피리미딘아민의 용도
KR10-2003-7012939A KR20040007485A (ko) 2001-04-05 2002-04-05 알레르기성 질환과 같은 비만세포계 질병에 대한ｎ-페닐-2-피리미딘아민의 용도

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR10-2003-7012939A KR20040007485A (ko) 2001-04-05 2002-04-05 알레르기성 질환과 같은 비만세포계 질병에 대한ｎ-페닐-2-피리미딘아민의 용도

Country Status (18)

Country Link
EP (1) EP1389113A1 (ru)
KR (2) KR20090034998A (ru)
CN (1) CN1529602A (ru)
AU (1) AU2002307140B2 (ru)
BR (1) BR0208663A (ru)
CA (1) CA2443092A1 (ru)
CZ (1) CZ20032705A3 (ru)
GB (1) GB0108606D0 (ru)
HU (1) HUP0303751A3 (ru)
IL (1) IL158061A0 (ru)
MX (1) MXPA03009058A (ru)
NO (1) NO325454B1 (ru)
NZ (1) NZ528934A (ru)
PL (1) PL363080A1 (ru)
RU (1) RU2304436C2 (ru)
SK (1) SK12312003A3 (ru)
WO (1) WO2002080925A1 (ru)
ZA (1) ZA200307563B (ru)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE343415T1 (de) 2001-06-29 2006-11-15 Ab Science Die verwendung von c-kit hemmer zur behandlung von entzündlichen darmerkrankungen
JP2005500041A (ja) 2001-06-29 2005-01-06 アブ サイエンス 強力で選択的かつ非毒性のｃ−ｋｉｔ阻害剤
DK1401413T3 (da) 2001-06-29 2007-03-26 Ab Science Anvendelse af tyrosinkinaseinhibitorer til behandling af allergiske sygdomme
JP2004537537A (ja) 2001-06-29 2004-12-16 アブ サイエンス 炎症性疾患を治療するためのチロシンキナーゼ阻害剤の使用法
GB0201882D0 (en) * 2002-01-28 2002-03-13 Novartis Ag Organic compounds
AU2003226209B2 (en) * 2002-03-21 2008-10-23 Dana-Farber Cancer Institute, Inc. Inhibition of cell death responses induced by oxidative stress
US8450302B2 (en) 2002-08-02 2013-05-28 Ab Science 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
CN100491374C (zh) 2002-08-02 2009-05-27 Ab科学公司 2-(3-氨基芳基)氨基-4-芳基-噻唑及其作为c-kit抑制剂的应用
WO2004076693A1 (en) * 2003-02-27 2004-09-10 Ab Science Tailored treatment suitable for different forms of mastocytosis
AU2003232650A1 (en) * 2003-05-06 2004-11-26 Il Yang Pharm Co., Ltd. N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof
TWI324604B (en) 2003-06-18 2010-05-11 Novartis Ag New use of staurosporine derivatives
WO2005115385A1 (en) * 2004-05-24 2005-12-08 Ab Science Use of c-kit inhibitors for treating acne
CA2578122A1 (en) * 2004-08-27 2006-03-02 Gpc Biotech Ag Pyrimidine derivatives
JP5129123B2 (ja) * 2005-05-02 2013-01-23 ノバルティス アーゲー 全身性肥満細胞症の処置のためのピリミジルアミノベンズアミド誘導体の使用
KR100845278B1 (ko) * 2006-08-04 2008-07-09 포항공과대학교 산학협력단 비만 세포의 활성을 유도하는 펩타이드 및 이를 포함하는면역조절제
CN102421430B (zh) * 2009-04-06 2014-06-25 纽若泰克制药株式会社 用于预防或治疗烧伤的药物组合物
CN103058935B (zh) * 2013-01-15 2015-05-06 四川大学 一种嘧啶类化合物及其制备方法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO4940418A1 (es) * 1997-07-18 2000-07-24 Novartis Ag Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso

Also Published As

Publication number Publication date
GB0108606D0 (en) 2001-05-23
NO325454B1 (no) 2008-05-05
HUP0303751A3 (en) 2005-06-28
CN1529602A (zh) 2004-09-15
WO2002080925A1 (en) 2002-10-17
MXPA03009058A (es) 2004-11-22
HUP0303751A2 (hu) 2005-04-28
CA2443092A1 (en) 2002-10-17
BR0208663A (pt) 2004-03-09
IL158061A0 (en) 2004-03-28
PL363080A1 (en) 2004-11-15
NO20034414L (no) 2003-12-04
SK12312003A3 (sk) 2004-02-03
AU2002307140B2 (en) 2006-02-16
RU2003130635A (ru) 2005-02-10
NZ528934A (en) 2006-10-27
NO20034414D0 (no) 2003-10-02
ZA200307563B (en) 2004-04-21
RU2304436C2 (ru) 2007-08-20
EP1389113A1 (en) 2004-02-18
CZ20032705A3 (en) 2004-06-16
KR20040007485A (ko) 2004-01-24

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