PL363080A1 - Use of n-phenyl-2-pyrimidineamine derivativea against mast cell-based diseases like allergic disorders - Google Patents

Use of n-phenyl-2-pyrimidineamine derivativea against mast cell-based diseases like allergic disorders

Info

Publication number
PL363080A1
PL363080A1 PL02363080A PL36308002A PL363080A1 PL 363080 A1 PL363080 A1 PL 363080A1 PL 02363080 A PL02363080 A PL 02363080A PL 36308002 A PL36308002 A PL 36308002A PL 363080 A1 PL363080 A1 PL 363080A1
Authority
PL
Poland
Prior art keywords
derivativea
pyrimidineamine
phenyl
mast cell
allergic disorders
Prior art date
Application number
PL02363080A
Other languages
Polish (pl)
Inventor
Michael Heinrich
Kenichi Koike
Atsushi Komiyama
Motowo Nakajima
Kouichi Takeuchi
Original Assignee
Novartis Ag
The Government Of The United States Of America, As Represented By The Department Of Veterans Affairs
Oregon Health And Science University
Kenichi Koike
Atsushi Komiyama
Kouichi Takeuchi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, The Government Of The United States Of America, As Represented By The Department Of Veterans Affairs, Oregon Health And Science University, Kenichi Koike, Atsushi Komiyama, Kouichi Takeuchi filed Critical Novartis Ag
Publication of PL363080A1 publication Critical patent/PL363080A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
PL02363080A 2001-04-05 2002-04-05 Use of n-phenyl-2-pyrimidineamine derivativea against mast cell-based diseases like allergic disorders PL363080A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0108606.5A GB0108606D0 (en) 2001-04-05 2001-04-05 Organic compounds
PCT/US2002/010742 WO2002080925A1 (en) 2001-04-05 2002-04-05 Use of n-phenyl-2-pyrimidineamine derivativea against mast cell-based diseases like allergic disorders

Publications (1)

Publication Number Publication Date
PL363080A1 true PL363080A1 (en) 2004-11-15

Family

ID=9912339

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02363080A PL363080A1 (en) 2001-04-05 2002-04-05 Use of n-phenyl-2-pyrimidineamine derivativea against mast cell-based diseases like allergic disorders

Country Status (18)

Country Link
EP (1) EP1389113A1 (en)
KR (2) KR20040007485A (en)
CN (1) CN1529602A (en)
AU (1) AU2002307140B2 (en)
BR (1) BR0208663A (en)
CA (1) CA2443092A1 (en)
CZ (1) CZ20032705A3 (en)
GB (1) GB0108606D0 (en)
HU (1) HUP0303751A3 (en)
IL (1) IL158061A0 (en)
MX (1) MXPA03009058A (en)
NO (1) NO325454B1 (en)
NZ (1) NZ528934A (en)
PL (1) PL363080A1 (en)
RU (1) RU2304436C2 (en)
SK (1) SK12312003A3 (en)
WO (1) WO2002080925A1 (en)
ZA (1) ZA200307563B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE343415T1 (en) 2001-06-29 2006-11-15 Ab Science THE USE OF C-KIT INHIBITORS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
ATE330608T1 (en) 2001-06-29 2006-07-15 Ab Science THE USE OF N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES
PT1401413E (en) 2001-06-29 2007-02-28 Ab Science Use of tyrosine kinase inhibitions for treating allergic diseases
JP2005500041A (en) 2001-06-29 2005-01-06 アブ サイエンス Potent, selective and non-toxic C-KIT inhibitor
GB0201882D0 (en) * 2002-01-28 2002-03-13 Novartis Ag Organic compounds
US20060128720A1 (en) * 2002-03-21 2006-06-15 Kufe Donald W Inhibition of cell death responses induced by oxidative stress
DK1525200T3 (en) 2002-08-02 2007-12-03 Ab Science 2- (3-aminoaryl) amino-4-aryl-thiazoles for disease treatment
US8450302B2 (en) 2002-08-02 2013-05-28 Ab Science 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
US20080025916A1 (en) * 2003-02-27 2008-01-31 Ab Science Tailored Treatment Suitable for Different Forms of Mastocytosis
WO2004099186A1 (en) * 2003-05-06 2004-11-18 Il Yang Pharm Co., Ltd. N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof
TWI324604B (en) * 2003-06-18 2010-05-11 Novartis Ag New use of staurosporine derivatives
WO2005115385A1 (en) * 2004-05-24 2005-12-08 Ab Science Use of c-kit inhibitors for treating acne
EP1786781A2 (en) * 2004-08-27 2007-05-23 GPC Biotech AG Pyrimidine derivatives
WO2006119154A1 (en) * 2005-05-02 2006-11-09 Novartis Ag Use of pyrimidylamimobenzamide derivatives for the treatment of systematic mastocytosis
KR100845278B1 (en) * 2006-08-04 2008-07-09 포항공과대학교 산학협력단 Peptide for activating mast cell and immunomodulator comprising the same
CN102421430B (en) * 2009-04-06 2014-06-25 纽若泰克制药株式会社 Pharmaceutical composition for treating or preventing burn injuries
CN103058935B (en) * 2013-01-15 2015-05-06 四川大学 Pyrimidine compound as well as preparation method and use for same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO4940418A1 (en) * 1997-07-18 2000-07-24 Novartis Ag MODIFICATION OF A CRYSTAL OF A DERIVATIVE OF N-PHENYL-2-PIRIMIDINAMINE, PROCESSES FOR ITS MANUFACTURE AND USE

Also Published As

Publication number Publication date
CN1529602A (en) 2004-09-15
AU2002307140B2 (en) 2006-02-16
NO20034414D0 (en) 2003-10-02
WO2002080925A1 (en) 2002-10-17
CA2443092A1 (en) 2002-10-17
ZA200307563B (en) 2004-04-21
RU2003130635A (en) 2005-02-10
KR20090034998A (en) 2009-04-08
IL158061A0 (en) 2004-03-28
HUP0303751A3 (en) 2005-06-28
NZ528934A (en) 2006-10-27
RU2304436C2 (en) 2007-08-20
NO20034414L (en) 2003-12-04
HUP0303751A2 (en) 2005-04-28
SK12312003A3 (en) 2004-02-03
CZ20032705A3 (en) 2004-06-16
GB0108606D0 (en) 2001-05-23
KR20040007485A (en) 2004-01-24
BR0208663A (en) 2004-03-09
MXPA03009058A (en) 2004-11-22
EP1389113A1 (en) 2004-02-18
NO325454B1 (en) 2008-05-05

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Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)