KR20070071500A - Stabilized nanovesicle containing oleaginous components and transparent cosmetic composition comprising the same - Google Patents

Abstract

Provided is a cosmetic composition comprising a stabilized nanovesicle including oil-phase ingredients, which shows excellent feeling of use and stability and has good long term moisturizing effect with very little skin irritation. The nanovesicle comprises 2.0-40.0 wt.% of an oily ingredient, 20.0-80.0 wt.% of a polyol, 0.1-20.0 wt.% of a surfactant, 0.5-20.0 wt.% of lecithin, 0.1-5.0 wt.% of a saturated or unsaturated C12-22 fatty acid, and 1.0-20.0 wt.% of purified water, has an average particle diameter of 5-40 nanometers and has the lipid monolayer vesicular structure. The transparent cosmetic composition comprises 0.1-30.0 wt.% of the nanovesicle and is in the form of solution, suspension, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, cleansing lotion or foundation.

Description

Stabilized Nanovesicle Containing Oleaginous Components And Transparent Cosmetic Composition Comprising the Same}

The present invention relates to a nano-vesicle and a transparent cosmetic composition comprising the same that can maintain transparency and stability even in toner and gel products.

In general, gelling cosmetics such as transparent solubilizing cosmetics, such as toners, essences, and packs, contain almost no oil, which gives the skin an instant refreshing and moisturizing effect and is not burdensome. However, it is more flexible than oil-containing products. And there is a problem that the softness falls and the long-term moisturizing power and moisturizing fall off the skin dry and rough.

To solve this problem, microemulsions containing dimethicone, esters, animal and vegetable oils and mineral oils are used, or small molecular weight ester oils which are completely dissolved in ethanol, short chain triglycerides and phenylmethicone A mixture of oils and surfactants such as PEG-60 hydrogenated castor oil and PEG-40 hydrogenated castor oil in ethanol has been used to improve the feeling of use and the effect of the product.

Microemulsions containing a variety of oils, unlike solubilization by micelles, are thermodynamically very stable translucent or transparent emulsifications formed by the use of significant amounts of surfactants, auxiliary surfactants and water in large amounts of oil. In this case, the oil contains a large amount of oil, which improves the flexibility, spreadability, and moisturizing power of the skin, but there is a problem in that the aggregation occurs between particles due to changes over time. As the concentration of the active agent must be high, skin irritation may be caused, and thus the frequency of products using the microemulsion is diminishing.

In addition, ethanol mixtures containing oils, oily ingredients and surfactants that dissolve in ethanol may increase skin flexibility, moist feeling and softness, thereby improving the feeling of use, but using a large amount of surfactant to make a transparent product. Solubilization can cause skin irritation problems. In addition, when the suspension is increased, agglomeration between particles occurs, and the particle size gradually increases, so that the oil component is separated into the upper layer, and separation occurs. As a result, the translucent state may be darker or lighter depending on the mixing conditions such as stirring speed and aeration during mixing, which may cause problems in the reproducibility of commercialized products.

The present inventors have diligently researched to solve the conventional problems caused by the transparent cosmetics, and as a result, the cosmetic composition including the nano-vesicles made of specific ingredients can be used to maintain transparency even in the transparent form of the formulation, It was confirmed that the stability is very good and long-term moisturizing effect is also very small irritation to the skin and completed the present invention.

Accordingly, it is an object of the present invention to provide a transparent cosmetic composition composed of stabilized nanovesicles containing an oily component.

Other objects and advantages of the present invention will become apparent from the following detailed description and claims.

According to one aspect of the invention, the invention provides (i) 2.0-40.0% by weight oily component, (ii) 20.0-80.0% by weight polyol, (iii) 0.1-20.0% by weight surfactant, (iv) lecithin 0.5-20.0 Wt%, (v) 0.1-5.0 wt% of saturated or unsaturated fatty acids of the C _12-22 alkyl chain and (vi) 1.0-20.0 wt% of purified water, with an average particle diameter of 5-40 nm and a lipid monolayer vesicle structure Phosphorus nanovesicles are provided.

As used herein, the term "nanovesicle" refers to a vesicular structure with a nanounit size and is distinguished from a nanoliposome consisting of a lipid bilayer in that it is surrounded by a lipid monolayer.

The nanovesicle of the present invention has an average particle diameter of 5-40 nm, preferably 10-40 nm. When the average particle diameter of the nanovesicle exceeds 40 nm, the technical effect to be achieved in the present invention, that is, the improvement of the usability and stability is very weak.

The oil component used in the preparation of the nanovesicle of the present invention may be a variety of oils known in the art, preferably hydrocarbon-based oils such as hexadecane and paraffin oil; Synthetic synthetic oils; Silicone oils such as dimethicone and cyclomethicone series; Animal and vegetable oils such as sunflower oil, corn oil, soybean oil, avocado oil, sesame oil and fish oil; Ethoxylated alkyl ether oils; Propoxylated alkyl ether oils; Sphingoidoid lipids such as phytosphingosine, sphingosine and sphinginine; Ceramides; Cerebroside; cholesterol; Cytosterol; Cholesteryl sulfate; Cytosteryl sulfate; C _10-40 fatty alcohols or C _10-40 fatty acids. The amount of the oil component is 2.0-40.0% by weight, preferably 10.0-30.0% by weight based on the total weight of nanovesicles.

The polyol which is another component used in the preparation of the nanovesicle of the present invention is not particularly limited, and preferably, propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin, methylpropanediol, isoprene glycol, Pentylene glycol, erythritol, ziitol and sorbitol. The amount used is 20.0-80.0% by weight, preferably 30.0-70.0% by weight, based on the total weight of the nanovesicle.

The surfactant used in the cosmetic composition of the present invention is an anionic surfactant or alkoxylated alkyl selected from the group consisting of alkylacylglutamate, alkyl phosphate, alkyl lactylate, alkyl sulfate, isothionate, sarcosinate and taurate. Nonionic surfactants selected from the group consisting of ethers, alkoxylatedalkyl esters, alkylpolyglycosides, polyglyceryl esters and sugar esters. The cosmetic composition of the present invention may be used alone or mixed with anionic surfactants or nonionic surfactants.

On the other hand, in the preparation of the nano-vesicle of the present invention, when a surfactant containing a higher fatty acid is used, the need for fatty acids required for the production of nano-vesicles can be eliminated. The amount of the surfactant used is 0.1-20.0% by weight, preferably 0.5-10.0% by weight based on the total weight of the nanovesicle.

The lecithin used in the production of the nanovesicle of the present invention is a naturally occurring unsaturated lecithin or saturated lecithin extracted from soybean or egg yolk. Typically, lecithin derived from nature has 23-95% phosphatidyl choline and 20% or less phosphadidylethanolamine. The amount of lecithin used is 0.5-20.0% by weight based on the total weight of the nanovesicles, preferably 2.0-6.0% by weight.

The saturated or unsaturated fatty acids of the C _12-22 alkyl chains used in the manufacture of the nanovesicles of the present invention are selected from the group consisting of lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid and linoleic acid. The amount used is 0.1-5.0% by weight, preferably 0.5-3.0% by weight based on the total weight of nanovesicles.

The amount of purified water used in the present invention is 1.0-20.0% by weight, preferably 5.0-15.0% by weight.

The preparation of the nanovesicles of the present invention may be accomplished through various methods known in the art, but most preferably, a mixture including the above components is applied to a high pressure homogenizer. The production of nanovesicles by high pressure homogenizer can be carried out under various conditions (eg pressure, frequency, etc.) depending on the desired particle size, preferably 1-5 times high pressure homogenizer under 600-1200 bar pressure. The nanovesicles are made by passing through the Niger.

According to another aspect of the present invention, the present invention provides a transparent cosmetic composition comprising the nano-vesicle described above.

The content of nanovesicles in the transparent cosmetic composition may vary depending on the desired suspension, but is 0.1-30.0% by weight relative to the total weight of the cosmetic composition, preferably 1.0-10.0% by weight. In addition, the nanovesicles of the present invention can be applied to general cosmetics as well as transparent cosmetics, the content of the nanovesicles of the present invention when applied to general cosmetics is 0.1-50.0% by weight, preferably 1.0 based on the total weight of the cosmetic composition -30.0 weight percent.

Cosmetic compositions of the present invention may be prepared in any formulation conventionally prepared in the art and include, for example, solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, surfactant-containing cleansing , Oils, powder foundations, emulsion foundations, wax foundations and sprays, and the like, but are not limited thereto. More specifically, it may be prepared in a transparent form of the formulation, such as softener, essence, pack, shampoo, body cleanser, hair lotion or cleaner.

When the formulation of the present invention is a paste, cream or gel, animal oils, vegetable oils, waxes, paraffins, starches, trachants, cellulose derivatives, polyethylene glycols, silicones, bentonites, silicas, talc or zinc oxide may be used as carrier components. Can be.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used, in particular in the case of a spray, additionally chlorofluorohydrocarbon, propane Propellant such as butane or dimethyl ether.

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizer or emulsifier is used as the carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 Fatty acid esters of, 3-butylglycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan.

When the formulation of the present invention is a suspension, liquid carrier diluents such as water, ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, microcrystals Soluble cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

When the formulation of the present invention is a surfactant-containing cleansing, the carrier component is aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide. Ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives or ethoxylated glycerol fatty acid esters and the like can be used.

The transparent cosmetic composition to which the nano-vesicle of the present invention is added has superior stability of the product, excellent transparency, excellent long-term moisturizing effect on the skin, and almost no skin irritation, compared to the conventional cosmetic composition to which the opacifying agent is added. It does not cause any damage and the product is also excellent. This advantageous effect of the cosmetic of the invention is illustrated in detail by the following examples. The nanovegicle of the present invention is used in transparent cosmetic products such as softeners, essences, packs, shampoos, body cleansers, hair brushing lotions and cleansers, etc., to increase skin moisturizing and flexibility while maintaining transparency, Increases visibility and greatly improves usability and storage stability.

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are only for illustrating the present invention in more detail, it is to those skilled in the art that the scope of the present invention is not limited by these examples in accordance with the gist of the present invention. Will be self-evident.

Preparation Example A: Preparation of Nanovesicle

To prepare a nanoveggle of Preparation Examples 1 to 11 with the composition of Table 1. First, phase B (lecithin) and phase C (anionic surfactant and nonionic surfactant) are added to phase A (polyol), and then wetted uniformly, and then phase D (oil component) on phases A, B, and C. , Phase E (water) and phase F (potassium hydroxide) were added, and the mixture was heated and mixed to 70-77 ° C. and stirred uniformly. Subsequently, the mixture was passed through a high pressure homogenizer 1-5 times under conditions of 600-1,200 bar and cooled to prepare a nanovesicle having a particle size of 10-40 nm in diameter.

Prize ingredient Preparation Example 1 Preparation Example 2 Preparation Example 3 Preparation Example 4 Preparation Example 5 Preparation Example 6 Preparation Example 7 Preparation Example 8 Preparation Example 9 Preparation Example 10 Preparation Example 11 A Propylene glycol 40.0 - - - - - - - - 60.0 - 1,3-butylene glycol - 45.0 - - - - - - - - - glycerin - - 50.0 50.0 50.0 50.0 50.0 50.0 - - 50.0 B lecithin 3.0 6.0 3.0 - - - 4.0 - - - - Hydrogenated Lecithin - - - 6.0 6.0 6.0 - 8.0 8.0 8.0 6.0 C Octyldodeceth-25 1.5 - - - - - 1.5 1.5 2.0 2.0 2.0 Polysorbate-80 - 1.5 - - - - 0.5 - - - - Alkyl lactylates - - 1.5 - - - - 0.5 - - - Stearic acid - - - 1.5 - - - - 0.5 Alkylacyl glutamate - - - - 1.5 - - - - 0.5 Taurate - - - - - 1.5 - - - - 0.5 D Dimethicone (100cs) 15.0 - - - - - - - - - - Caprylic / Capric Triglycerides - 20.0 - - 15.0 15.0 15.0 - - - - Jojoba oil - - 15.0 - - - - 30.0 35.0 - - Squalane - - - 20.0 - - - - - - - Tocopheryl acetate - - - - - - - - - 20.0 20.0 cholesterol - - - - 5.0 - 2.5 - - - - Ceramide - - - - - 5.0 2.5 - - - - E Purified water To. 100 To. 100 To. 100 To. 100 To. 100 To. 100 To. 100 To. 100 To. 100 To. 100 To. 100 F Potassium hydroxide Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity

Production Example  B: Nano Vegicle  Preparation of Containing Soft Skin

To a flexible cosmetic lotion containing the nano-vesicles prepared in Preparation Example A in the composition of Table 2 was prepared by a conventional cosmetic preparation method. As a comparative example, instead of the nanovesicle of the present invention, a flexible lotion was prepared by adding only tocopheryl acetate, which is an existing opacifying agent (oil component).

ingredient Example 1-1 Example 1-2 Comparative Example 1 Comparative Example 2 Distilled water To. 100 To. 100 To. 100 To. 100 glycerin 3.0 3.0 3.0 3.0 1,3-butylene glycol 3.0 3.0 3.0 3.0 DL-panthenol 0.2 0.2 0.2 0.2 EDTA-2Na 0.02 0.02 0.02 0.02 Hyaluronic acid liquid 2.0 2.0 2.0 2.0 ethanol 7.0 7.0 7.0 7.0 PEG-60 Hydrogenated Castor Oil 0.2 0.2 0.8 1.6 Incense, preservative Quantity Quantity Quantity Quantity Nano-vesicle of Preparation Example 10 5.0 10.0 - - Tocopheryl Acetate - - 1.0 2.0

Experimental Example 1: Measurement of the transparency and product stability of the cosmetic

Transparency and product stability of the cosmetic preparation prepared in Preparation Example B was measured.

<1-1> Suspension Measurement

Suspension refers to the degree to which the light is reflected, the lower the value is, the higher the light transmittance, it can be determined that the good transparency. Since Example 1-1, Comparative Example 1, Example 1-2, and Comparative Example 2 contained the same amount of tocopheryl acetate in the same amount, the suspension degree of Example 1-1 and Comparative Example 1, Example 1-2, comparison After confirming the suspension degree of Example 2 by measuring the L value of the spectrophotometer (CM-3500d, MINOLTA), Table 3 shows the results.

Suspension of flexible lotion product Suspension (L value) product Suspension (L value) Example 1-1 25.12 Example 1-2 32.73 Comparative Example 1 79.67 Comparative Example 2 84.58

Through the results in Table 3, the cosmetics of Examples 1-1 and 1-2 containing the nano-vesicle of the present invention contains an oily component (tocopheryl acetate) of the same content compared to Comparative Examples 1 and 2, but also transparency It can be seen that the excellent.

<1-2> Stability Measurement

Each cosmetic product of Example 1-1, Example 1-2, Comparative Example 1, and Comparative Example 2 prepared in Preparation Example B was added to a transparent laboratory bottle (choja) in equal amounts at 45 ° for 20 days. Relative comparison was made by checking the stability state of. The experimental results are shown in Table 4 below.

Product stability test results product Stability Example 1-1 Stable up to 30 days Comparative Example 1 Separation starts on day 15 Example 1-2 Stable up to 30 days Comparative Example 2 Separation starts on day 12

Through the results of Table 4, the cosmetic products of Examples 1-1 and 1-2 using the nano-vesicles of the present invention is very stable because there is no separation at 30 days without significantly affecting the concentration of the nano-vesicles included It can be seen that it is excellent.

Particle sizes of each product after the initial and 10 days were compared with Zetasizer (Zetasizer 3000HS, MALVERN) for more accurate stability checks, and the results are shown in Table 5 below.

Product particle size comparison result product Initial particle size Particle size after 10 days Example 1-1 28.7 nm 30.2 nm Comparative Example 1 108.3 nm 127.6 nm Example 1-2 32.9 nm 34.1 nm Comparative Example 2 136.2 nm 152.4 nm

As can be seen in Table 5, the particle size of the product using the nano-vesicle of the present invention can be seen that there is no problem in the formulation stability due to aggregation because there is no large change even after 10 days.

Experimental Example 2: Long-term skin moisturizing effect experiment

After dividing 20 healthy women into two groups A and B in a room with 25 ° C, 45% relative humidity and no air flow, group A used the cosmetics of Example 1-1 and Comparative Example 1, and group B After applying the cosmetics of 1-2 and Comparative Example 1 to the upper arm of the arm three times a day for 6 weeks, measuring the transdermal moisture loss (TEWL) using Tewameter TM 210 (C + K Electonic GmbH) and then changing the time The amount of change in TEWL (ΔTEWL) was calculated. Next, the moisturizing effect was measured by quantifying the moisture content of the skin from 0 to 150 with the change of electrical conductivity according to the epidermal moisture content using a Corneometer CM 820 PC (C + K Electronic GmbH). The measurement results are shown in Table 6 below.

Long-term skin moisturizing effect measurement result product 1 week later 6 weeks later ΔTEWL (g / hm ² ) Koniometer value ΔTEWL (g / hm ² ) Koniometer value Example 1-1 6.3 103 7.9 116 Example 1-2 6.8 112 8.7 128 Comparative Example 1 1.4 85 1.2 79

Through the results of Table 6, it can be seen that the product using the nano-vesicles of the present invention exhibits excellent long-term moisturizing power than the conventional opaque agent-using products. This can be considered that the nanovesicle of the present invention is easy to absorb the skin, thereby increasing the skin moisturizing power and thereby reducing the amount of transdermal moisture loss.

Experimental Example 3: Skin Irritation Experiment

Using the cosmetic products of Examples 1-1 and 1-2 prepared in Preparation Example B and the cosmetic products of Comparative Examples 1 and 2, the product was attached for 24 hours by a closed patch test method and then removed to check the degree of skin irritation. It was. As a criterion of determination, the relative comparison value was expressed as 0 for no skin irritation and 5 for severe cases. The experimental results are summarized in Table 7.

Skin irritation test result product Skin irritation degree product Skin irritation degree Example 1-1 0.5 Example 1-2 0.6 Comparative Example 1 1.4 Comparative Example 2 1.8

As can be seen in Table 7, the cosmetic product of the present invention using nano-vesicles was very low in the degree of skin irritation compared to the cosmetic product of the comparative example to which the conventional opacifier was added. This is because the amount of the surfactant (PEG-60 hydrogenated castor oil) used in the cosmetic product of the present invention was used much less than the cosmetic product of the comparative example, and the skin barrier was strengthened as the skin moisturizing power was increased, so that the skin of the external irritant source Infiltration is not easy and it is considered that the stimulus is reduced.

Experimental Example 4: Product Sensory Experiment

After 20 women in their 20s and 30s were divided into two groups A and B, Group A used the cosmetic products of Examples 1-2 and Comparative Example 1, and Group B used the cosmetic products of Examples 1-2 and Comparative Example 2. Each patient's left and right face are used twice daily for two mornings and evenings, and then evaluated for skin flexibility, moisture, stickiness, spreadability and absorbency. The best case is 5 and the worst case is 0. Relative comparison values were checked. The experimental results are summarized in Table 8 below.

Sensory test results of the product product flexibility Moist No stickiness Spreadability Absorbent Example 1-1 5.0 4.5 5.0 4.5 5.0 Example 1-2 5.0 5.0 4.5 4.0 4.5 Comparative Example 1 3.0 1.5 3.5 3.0 3.5 Comparative Example 2 3.0 2.5 3.0 1.0 1.0

Through the results of Table 8, the cosmetic composition containing the nano-vesicle of the present invention was very excellent in all parts of the sensory evaluation items, and significantly improved compared to the conventional cosmetic composition containing a conventional opacifier It can be seen that it shows a sensuality.

Hereinafter, examples of the cosmetic formulation of the present invention include a flexible lotion, an essence, a pack, a shampoo and a body cleanser containing the nanovesicle of the present invention, but the formulation of the cosmetic of the present invention is not necessarily limited thereto.

Formulation Example 1 Flexible Lotion

ingredient Formulation Example 1-1 (wt%) Formulation Example 1-2 (Weight%) Purified water To. 100 To. 100 glycerin 3.0 3.0 1,3-butylene glycol 3.0 3.0 DL-panthenol 0.2 0.2 EDTA-2Na 0.02 0.02 Sodium hyaluronate 2.0 2.0 ethanol 7.0 7.0 PEG-60 Hydrogenated Castor Oil 0.2 0.2 Preservative, incense Quantity Quantity Nano vesicles (production example-10) 5.0 - Nano vesicles (production example-11) - 10.0 Sum 100 100

Formulation Example 2: Essence

ingredient Formulation Example 2-1 (wt%) Formulation Example 2-2 (wt%) Purified water To. 100 To. 100 Hyaluronic acid liquid 5.0 5.0 β-glucan solution 3.0 3.0 DL-panthenol 0.3 0.3 Allantoin 0.1 0.1 IDT-2Na 0.02 0.02 Betaine 3.0 3.0 glycerin 5.0 5.0 Dipropylene glycol 4.0 4.0 ethanol 3.0 3.0 Fiji-60 Hydrogenated Castor Oil 0.2 0.2 Carbomer 0.15 0.15 Potassium hydroxide 0.07 0.07 Preservative, incense Quantity Quantity Nano vesicles (production example-10) 3.0 - Nano vesicles (production example-11) - 6.0 Sum 100 100

Formulation Example 3: Pack

ingredient Formulation Example 3-1 (wt%) Formulation Example 3-2 (Weight%) Purified water To.100 To.100 Fiji-4000 0.8 0.8 Polyvinyl Alcohol 217 10.0 10.0 Polyvinyl Alcohol 205 4.0 4.0 glycerin 2.0 2.0 Cellulose gum 0.4 0.4 DL-panthenol 0.2 0.2 ethanol 8.0 8.0 Octyldodeceth-25 0.2 0.2 Incense, preservative Quantity Quantity Nano vesicles (production example-10) 3.0 - Nano vesicles (production example-11) - 5.0 Sum 100 100

Formulation Example 4: Shampoo

ingredient Formulation Example 4-1 (wt%) Formulation Example 4-2 (Weight%) Purified water To.100 To.100 Alkyl sulfate (30%) 25.0 25.0 Alkyl ether sulfate (30%) 20.0 20.0 Alkyl amidobetaine (30%) 5.0 5.0 Propylene glycol 3.0 3.0 Lauramiddiei 4.0 4.0 IDT-2Na 0.1 0.1 Polyquaternium-10 0.05 0.05 NaCl Quantity Quantity Citric acid Quantity Quantity Preservative, coloring, fragrance Quantity Quantity Nano vesicles (production example-10) 3.0 - Nano vesicles (production example-11) - 5.0 Sum 100 100

Formulation Example 5: Body Cleanser

ingredient Formulation Example 5-1 (wt%) Formulation Example 5-2 (wt%) Purified water To.100 To.100 Alkyl ether saccharide (30%) 30.0 30.0 Alkyl ether sulfosuccinate (30%) 20.0 20.0 Alkyl amidobetaine (30%) 5.0 5.0 Propylene glycol 5.0 5.0 Betaine 5.0 5.0 Lauramiddiei 4.0 4.0 Cellulose gum 0.05 0.05 Hydrolyzed protein 0.1 0.1 NaCl Quantity Quantity Citric acid Quantity Quantity Preservative, coloring, fragrance Quantity Quantity Nano vesicles (production example-10) 2.5 - Nano vesicles (production example-11) - 4.0 Sum 100 100

As described in detail above, the present invention provides a stabilized nano-vesicle and a transparent cosmetic composition comprising the same. The cosmetic composition comprising the nanovesicle of the present invention is not only excellent in feeling and stability, but also has a long-term moisturizing effect and very little irritation to the skin.

Having described the specific part of the present invention in detail, it is apparent to those skilled in the art that the specific technology is merely a preferred embodiment, and the scope of the present invention is not limited thereto. Thus, the substantial scope of the present invention will be defined by the appended claims and equivalents thereof.

Claims (9)

(i) 2.0-40.0% by weight oily component, (ii) 20.0-80.0% by weight polyol, (iii) 0.1-20.0% by weight surfactant, (iv) 0.5-20.0% by weight lecithin, (v) C _12-22 alkyl Nanovesicles comprising 0.1-5.0% by weight of saturated or unsaturated fatty acids in the chain and 1.0-20.0% by weight of purified water, with an average particle diameter of 5-40 nm and a lipid monolayer vesicle structure. The oil-based component of claim 1, wherein the oily component is hydrocarbon oil, ester oil, silicone oil, animal or vegetable oil, ethoxylated alkyl ether oil, propoxylated alkyl ether oil, sphingoid lipid , Ceramide, Cerbroside, Cholesterol, Sitosterol, Cholesteryl Sulfate, Sitosteryl Sulfate, C _10-40 Fatty Alcohol and C _10-40 Fatty Acids. The method of claim 1, wherein the polyol is selected from the group consisting of propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin, methylpropanediol, isoprene glycol, pentylene glycol, erythritol, xyitol and sorbitol Nanovesicle made with. The method of claim 1, wherein the surfactant is an anionic surfactant and alkoxylated alkyl ether selected from the group consisting of alkylacylglutamate, alkyl phosphate, alkyl lactylate, alkyl sulfate, isothionate, sarcosinate, taurate And an alkoxylated alkyl ester, an alkyl polyglycoside, a polyglyceryl ester and a sugar ester, wherein the nanovesicle is at least one selected from the group consisting of nonionic surfactants. The _nanovegicle according to claim 1, wherein the saturated or unsaturated fatty acid of the C _12-22 alkyl chain is selected from the group consisting of lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid and linoleic acid. The nanovesicle of claim 1, wherein the average particle diameter of the nanovesicle is 10-40 nm. The nanovesicle of claim 1, wherein the nanovesicle is manufactured by passing 1 to 5 times through a high pressure homogenizer under a pressure of 600 to 1200 bar. The transparent cosmetic composition containing 0.1-30.0 weight% of nanovesicles of any one of Claims 1-7. 10. The transparent cosmetic composition according to claim 8, wherein the transparent cosmetic composition is a formulation of a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, cleansing lotion or foundation. .