KR101176523B1 - A Cosmetic Composition having phase transformation - Google Patents

Abstract

The present invention relates to a cosmetic composition having a change in appearance. More specifically, the present invention relates to a cosmetic composition for moisturizing skin containing acyl taurate anionic surfactant and having a property of temporarily causing cloudiness. Cosmetics containing the acyl taurate anionic surfactant of the present invention not only gives a visual effect due to the remarkable clouding phenomenon generated by simple skin massage, but also induces a change in the appearance of a cream in the case of a cosmetic having fluidity. It has the form of a translucent lotion, but has the advantage of having the flexibility and occlusion effect of the pack of the lipophilic emulsion type. In addition, the cosmetics of the present invention contains keratinocyte lipid components such as ceramide and cholesterol in the emulsified particles and liposomes that have been refined using nano emulsification technology to facilitate skin delivery and adhesion of keratinocyte lipid components within a short time after application of the product. It promotes the skin's moisturizing and moisturizing lasting efficiency.

Acyl Taurate Anionic Surfactant, Skin Moisturizing, Whitening, Change of Properties, Cosmetic

Description

A cosmetic composition having a phase change

The present invention relates to a cosmetic composition having a change in appearance.

In the cosmetic composition, the pack and mask formulations are used to cover the skin with moisture, moisturizers, and emollients to make the water in the stratum corneum saturated and then deliver nutrition and moisturizing ingredients deep into the skin. It has a function to do it. In particular, since it quickly normalizes skin barrier protection and keratin turnover and improves skin, it is a special care product with high satisfaction after use. However, it is true that during the busy life, the frequency of individual use at home is not high because of the long leaving time and complexity of use after applying the product.

Pack types come in a variety of forms and formulations, but can generally be classified into aqueous and lipophilic emulsion types. Aqueous type is a water-soluble polymer is blended, has a high moisture content, light, refreshing effect and a fresh feeling of advantage and to make the product transparent or semi-transparent in order to take advantage of the appearance characteristics of the formulation. However, due to the nature of these formulations, aqueous gel products cannot contain oily ingredients except for very small amounts of oils, such as insoluble or sparingly soluble flavorings or suspending agents, which provide inherent flexibility and long-term moisturizing effects. There is a drawback not to have. And since the lipophilic emulsification type contains a large amount of oil, it has moisturizing ability to prevent oiliness and pulling by skin dryness and lasting moisturizing effect, while lacking freshness and high melting point wax. The physical properties of the formulation according to the disadvantages of heavy and may feel heavy or bundled.

On the other hand, the cloudy effect by the visual effect of the cosmetic appearance contributes to the improvement of the satisfaction of the feeling of use. The cosmetic composition in the form of an emulsion in which cloudiness occurs when a product is used has been disclosed in Korean Patent Laid-Open Publication Nos. 2006-0018493 and 2008-0101536. Conventional techniques including the above are characterized in that the whitening phenomenon occurs in the content ratio of the nonionic surfactant and the higher fatty alcohol, but the cosmetics can be prepared with the stability of the formulation by the above methods. It was inadequate and had a short cloudy retention. In addition, insufficient turbidity is limited to applying skin lotion so that the skin lotion can be changed visually and sensory like a creamy form. To overcome this problem, some technologies are required to increase the content of higher fatty alcohols above a certain amount. Attempts to increase the turbidity, and as a result, there was a problem that affects the change over time of the formulation, such as gelling (gelling) occurs.

The technical problem to be solved by the present invention is to maintain the fluidity of the cosmetics, and induce a change in the appearance of the cream while the remarkable occurrence of the product whitening phenomenon even in simple skin massage, and has the appearance of a semi-transparent lotion but of the lipophilic emulsion type Acyl tau is trying to develop cosmetics that have the softness and occlusion effect of the pack, and which can effectively reduce the neglect time of cosmetics by promoting skin delivery and adhesion of lipid components between keratinocytes within a short time after application. By containing a rate-based anionic surfactant, not only the whitening phenomenon occurs remarkably even in simple skin massage, but also when the fine particles are finely granulated by using nanoemulsion technology together with the lipid component between keratinocytes, May increase skin adhesion and occlusion effect Therefore, it was confirmed that the skin moisturizing power and the moisturizing sustainability were completed, and the present invention was completed.

Accordingly, it is an object of the present invention to provide a cosmetic composition having a change in properties containing an acyl taurate anionic surfactant.

The above objects and advantages of the present invention will become apparent from the following detailed description and claims.

Although specific parts of the present invention are described in detail in the following detailed description, for those skilled in the art, these specific descriptions are merely preferred embodiments, and the scope of the present invention is limited thereto. It is obvious.

The present invention relates to a cosmetic composition having a change in appearance. More specifically, the present invention relates to a skin moisturizing cosmetic composition containing acyl taurate anionic surfactant to temporarily generate a clouding phenomenon and change the properties of the formulation. The skin moisturizing cosmetic containing the acyl taurate anionic surfactant of the present invention not only provides a visual effect of the remarkable clouding phenomenon caused by a simple skin massage, but also induces a change in the appearance of a cream when the cosmetic has fluidity. Although it has a form of a translucent lotion, there is an advantage in that it has the function of the softness and the occlusion effect of the pack of the lipophilic emulsion type. In addition, the cosmetics of the present invention contains keratinocyte lipid components such as ceramide and cholesterol in the emulsified particles and liposomes that have been refined using nano emulsification technology to facilitate skin delivery and adhesion of keratinocyte lipid components within a short time after application of the product. By promoting it, the effect of improving skin moisturizing and moisturizing persistence in a short time is excellent.

The present invention relates to a cosmetic composition having a change in appearance. More specifically, the present invention provides a cosmetic having the effect of temporarily causing cloudiness and changing the properties of the formulation by containing an acyl taurate anionic surfactant as an active ingredient.

Hereinafter, the present invention will be described more specifically.

The cosmetic of the present invention contains an acyl taurate anionic surfactant as an active ingredient. In addition, the cosmetic of the present invention contains higher fatty alcohol as an active ingredient. In addition to the acyl taurate anionic surfactant and higher fatty alcohol, the cosmetic of the present invention may further include polyol, lecithin, ceramide, cholesterol and derivatives thereof, and residual water. More specifically, the cosmetic of the present invention relates to a cosmetic composition comprising a nano-emulsifying composition (for example, a nano-emulsion) composed of the above-mentioned active ingredient and components, the cosmetic of the present invention comprising the nano-emulsifying composition The composition has a translucent appearance and the whitening phenomenon which is remarkably generated by simple skin massage not only gives a visual effect, but also induces a change in the appearance of the fluid formulation into a creamy form, and it is also fine using nano emulsification technology. By incorporating lipid components between keratinocytes such as ceramide and cholesterol in the emulsified particles and liposomes, there is a characteristic that can improve not only the stability of the cosmetics over time but also the skin absorption and moisturizing effect.

As used herein, the acyl taurate-based anionic surfactant is an active ingredient that causes a cloudiness of the cosmetic of the present invention, and has excellent foaming and low skin irritation, and when used in combination with a higher fatty alcohol, it is more fine and dense and rich. It can be used as a time indicator that can inform the time of use of cosmetics because it can form white cloud and not only give a visual and sensory effect like cream film but also adjust the maintenance time of generated white cloud. There is this. Such acyl taurate-based anionic surfactants may include, but are not limited to, sodium methyl cocoyl taurate, sodium methyl lauroyl taurate, sodium methyl myristoyl taurate, and mixtures thereof.

In addition, the higher fatty alcohol component is characterized in that at least one selected from cetyl alcohol, stearyl alcohol, cetostearyl alcohol, behenyl alcohol and the like.

At this time, the component is 0.1 to 10.0% by weight, preferably 0.3 to 5.0% by weight, and the higher fatty alcohol is 0.5 to 15.0% by weight, preferably the acyl taurate anionic surfactant based on the total weight of the cosmetic composition. It is contained in 1.0 to 10.0 wt%.

Lecithin constituting the cosmetic of the present invention is obtained from soybeans, eggs, plant seeds and the like, having a fatty acid chain having 12 to 24 carbon atoms, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidyl inositol and other phospholipids. Consists of a mixture of fatty acids. In addition, since the double bond of the fatty acid chain is easily oxidized by water or active oxygen, hydrogenated lecithin which has removed the double bond of the fatty acid chain by a hydrogenation reaction may be used. The content of lecithin or saturated lecithin used in the present invention is 0.1 to 10% by weight, more preferably 0.5 to 5.0% by weight based on the total weight of the cosmetic composition.

Ceramides that constitute the cosmetic composition of the present invention include sphinosine derived from nature such as copper, plants such as synthetic, fermented, yeast, and derivatives thereof. The ceramide component used in the present invention is contained in an amount of 0.1 to 10.0% by weight, preferably 0.1 to 5.0% by weight, based on the total weight of the cosmetic composition.

Cholesterol and its derivatives, which constitute the cosmetic composition of the present invention, are cholesteryl alkylates and cholesterol such as cholesterol and cholesteryl stearate and cholesteryl isostearate made by esterifying fatty acids derived from synthesis and nature. Cholesteryl glutamate made by esterifying amino acids to phytosterols, phytosterols derived from plants and phytosteryl alkylates and phytosterols such as phytosteryl stearate and phytosteryl isostearate made by esterifying fatty acids Phytosteryl glutamate produced by esterification of the same. The content of cholesterol and its derivatives used in the present invention is 0.1 to 10.0% by weight, preferably 0.1 to 5.0% by weight based on the total weight of the cosmetic composition.

The oil component constituting the cosmetic composition of the present invention may be collected and used inside the nanoemulsion particles of the cosmetic, and various oils known in the art may be used, for example, hydrocarbons such as hexadecane and paraffin oil. Synthetic oils such as oils, isopropyl myristate, silicone oils such as dimethicone and cyclomethicone, sunflower oil, corn oil, soybean oil, avocado oil, sesame oil, jojoba oil, nut oil, squalane and fish oil Similar animal and vegetable oils, ethoxylated alkyl ether oils, propoxylated alkyl ether oils and the like can be used. The content of the oil component used in the cosmetic composition of the present invention is 2.0 to 30.0% by weight, preferably 3.0 to 20.0% by weight, based on the total weight of the cosmetic composition.

The polyol constituting the cosmetic of the present invention is not particularly limited, and preferably, propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin, methylpropanediol, isoprene glycol, pentylene glycol, erythritol, and xyitol , Sorbitol and mixtures thereof. The content of the polyol used in the cosmetic composition of the present invention is 20.0 to 80.0 wt% with respect to the total weight of the cosmetic composition, preferably 30.0 to 60.0 wt%.

The cosmetic composition of the present invention can be made through various methods known in the art. For example, the cosmetic composition of the present invention is made of a cosmetic after the nano-emulsifying composition is prepared. In the present invention, the nano-emulsifying composition has a form of a conventional liposome, and the mean droplet size is 10 to 500 nm, preferably 30 nm to 250 nm, and most preferably 50 nm to 150 nm. When the average droplet size of the nano-emulsifying composition exceeds 500nm, skin penetration and formulation stability are very weak among the technical effects to be achieved in the present invention. In addition, nano-emulsifying compositions are mutually spontaneous bonding and colloidal particles of particles composed of amphiphilic molecules having water-soluble and oil-soluble moieties, and microvesicles (vesicles) having a hydrophilic space inside and a closed double lipid membrane outside. / A type of pocket) and has a double membrane structure similar to a cell membrane. The nanoemulsifying composition includes a water-soluble molecule in a central hydrophilic space, and attaches a lipid-soluble molecule to an external lipid bilayer, or combines positive and negative charge materials. The biggest feature of the nano-emulsifying composition is that it is easy to change the structure due to the variety and elasticity, and by changing the structure and components can be provided a completely new physical properties, functions and uses. Nano-emulsification composition here has the advantages of excellent biocompatibility, degradability, stability can be widely used in cosmetics and drug delivery as a variety of materials.

According to a preferred embodiment of the present invention, the nanoemulsifying composition of the present invention is prepared by applying a mixture comprising the above-mentioned components of the present invention to a high pressure homogenizer. The high pressure homogenizer is called high pressure emulsification and refers to the second emulsification through the high pressure homogenizer through the emulsion emulsified firstly with a general stirrer or homomixer. At this time, the process of the oil particles to be micronized is to make the emulsified particles small by the pressure fluctuation, cavitation, collision force generated when the emulsion passes at high pressure and atmospheric pressure 1 atm. Nanoemulsion preparation by high pressure homogenizer can be carried out under various conditions (e.g. pressure, frequency, etc.) depending on the desired particle size, preferably through 1 to 5 times high pressure homogenizer under 600 to 1,200 atm. It is to prepare a nano-emulsifying composition and to use it in the preparation of the cosmetic composition of the present invention.

In addition to the active ingredient, the components included in the cosmetic composition may include various components that maintain the activity of the biological component such as preservatives, osmotic agents, pH adjusters, buffers, stabilizers, aluminum hydroxide, aluminum phosphate, surfactants, liposomes, thickeners, and the like. Ingredients commonly used in cosmetic compositions such as, but not limited to, antioxidants, stabilizers, solubilizers, conventional adjuvants such as vitamins, pigments and flavors, and carriers, and the like.

Performing a cosmetic method comprising applying the cosmetic composition comprising the active ingredient of the present invention to the skin of a person, it is possible to induce a change in the sensory properties of the feeling as well as the visual effect by the remarkable clouding phenomenon generated by a simple skin massage In addition, the skin moisturizing effect can be obtained.

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are only for illustrating the present invention in more detail, and the scope of the present invention is not limited by these examples in accordance with the gist of the present invention to those skilled in the art. Will be self-evident.

Preparation Example 1 Preparation of Nanoemulsion

In Table 1, Examples 1 and 2 (the formulation does not include cholesterol and ceramide in Example 1), Comparative Example 1 (the formulation does not include acyl taurate anionic surfactant in Example 1) ), Comparative Example 2 (prescription containing no higher fatty alcohol in Example 1), Comparative Example 3 (prescription containing nonionic surfactant instead of acyl taurate anionic surfactant in Example 1) Prepared. In the method for producing a nanoemulsion composition, each phase A (water phase) and phase B (lipid phase) are heated to 80 ° C. to form a single solution, followed by stirring while gradually adding phase A (water phase) to phase B (geological phase). After homogenizing to make the primary emulsion, the primary emulsion was passed through a high-pressure homogenizer three times at 1,000 atmospheres to prepare a secondary nanoemulsion composition.

division Name Comparative Example 1 Comparative Example 2 Comparative Example 3 Example 1 Example 2 A Purified water Balance Balance Balance Balance Balance glycerin 30.0 30.0 30.0 30.0 30.0 Sodium methyl cocoyl taurate - 3.0 - 3.0 3.0 B Caprylic / capric triglyceride 20.0 20.0 20.0 20.0 20.0 C14-22 Alcohol / C12-20 Alkyl Glucoside - - 6.0 - - Cetearyl Alcohol 8.0 - 8.0 8.0 8.0 cholesterol 1.5 1.5 1.5 1.5 - Ceramide 3 1.5 1.5 1.5 1.5 - Hydrogenated Lecithin 9.0 9.0 3.0 9.0 9.0 ethanol 6.0 6.0 6.0 6.0 6.0

Experimental Example  1: nano Emulsion  Appearance, particle size and stability evaluation

Each sample obtained in Comparative Examples 1 to 3 and 1 and 2 was taken the next day of preparation to observe the appearance of the formulation, and the average particle size was measured using a particle size analyzer. Particle size was measured using a dynamic light scattering method (Zetasizer 3000HS), and the scattering angle was fixed at 90 degrees and the temperature was maintained at 25 ℃. In addition, in order to confirm the storage stability of the nano-emulsifying composition, the particle size change was measured by observing the average particle size of each sample obtained in Comparative Examples 1 to 3, Examples 1 and 2 for 4 weeks at 30 ° C. The results are shown in Table 2 below.

division transparency Particle Size (nm) Particle size after 4 weeks (nm) Comparative Example 1 ++ 90 159 Comparative Example 2 +++ 53 58 Comparative Example 3 + 170 260 Example 1 ++ 87 94 Example 2 ++ 72 84

Nanoparticles obtained through a high pressure homogenizer were prepared as a bluish translucent suspension. Looking at the results of Table 2, when using a mixture of lecithin and sodium methyl cocoyl taurate (Example 1), there is an effect that the average particle diameter is reduced compared to the nano-emulsification composition (Comparative Example 1) prepared only with lecithin In addition, it can be confirmed that even in the particle size after 4 weeks, it maintains a stable particle size and excellent long-term storage stability. Comparative Example 2, which is a formulation containing no higher fatty alcohol in Example 1, had the best transparency among the obtained nanoemulsions, and the average particle size was stable after 4 weeks, whereas in Example 1, the non-acyltaurate-based anionic surfactant was used. In Comparative Example 3, which is a formulation containing an ionic surfactant, the transparency of the nanoemulsion was the lowest, and it can be seen that long-term storage stability was not maintained.

Manufacturing example  2: nano Emulsion  Containing Cosmetics  Preparation of the composition

Gel-like cosmetics containing nanoemulsions containing the acyl taurate-based anionic surfactant and higher fatty alcohol, which are the active ingredients of the present invention, were prepared as follows in the composition and content of Table 3.

At room temperature, B and C phases were slowly added and uniformly mixed to prepare a cosmetic containing a nanoemulsion, and phase C was 30% of Examples 1 and 2 and Comparative Examples 1 to 3, respectively, prepared in Preparation Example 1. Added freshly.

Name compare
Prescription Example 1 compare
Prescription Example 2 compare
Prescription Example 3 Prescription Example
One Prescription Example
2 A Purified water Balance Balance Balance Balance Balance Butylene glycol 15.0 15.0 15.0 15.0 15.0 Fiji-8 10.0 10.0 10.0 10.0 10.0 Fiji-32 2.0 2.0 2.0 2.0 2.0 Disodium iodide 0.03 0.03 0.03 0.03 0.03 B Carbomer 0.1 0.1 0.1 0.1 0.1 corrector Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount antiseptic Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount incense Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount C Comparative Example 1 30.0 - - - - Comparative Example 2 - 30.0 - - - Comparative Example 3 - - 30.0 - - Example 1 - - - 30.0 - Example 2 - - - - 30.0

Experimental Example  2 : White cloud Generating force  evaluation

The initial turbidity occurrence and the turbidity retention of the cosmetic composition were evaluated using Comparative Preparation Examples 1 to 3 and Formulation Examples 1 and 2 prepared in Preparation Example 2. In the experiment, 0.50 g of each sample of Comparative Prescription Examples 1-3 and Prescription Examples 1 and 2 was uniformly coated on the back of the hand with an applicator, and then rubbed 20 times by hand, and the initial turbidity generated was visually determined. Shown in

From the results of FIG. 1, it can be seen that the whitening occurrence power of Formulation Examples 1 and 2 corresponding to the cosmetic of the present invention is much superior to Comparative Prescription Examples 1-3.

Experimental Example  3: skin Moisturizing  evaluation

Skin moisturizing power for each cosmetic composition prepared according to Preparation Example 2 was measured as follows. Skin moisturizing experiments Comparative Examples 1 and 3 are similar to Prescription Example 1 in order to prove that the degree of turbidity is similar and the acyl taurate anionic surfactant, which is an active ingredient of the present invention, is superior to conventional nonionic surfactants. 3 was tested by comparison, and Comparative Example 2 was excluded from the experiment because there was no clouding phenomenon.

Twenty healthy adult men and women who feel dry skin were randomly selected through a questionnaire and 5 μl of each of Comparative Example 3, Formula 1, and Formula 2 were applied to the size of 2 × 2 cm in the upper arm. The amount of skin moisture up to 8 hours at intervals of 2 hours after application was measured by using the Corniometer CM 820 (Corage + Khazaka, Germany). The amount of skin moisture was measured by quantification. The amount of skin moisture measured is shown in Table 4 below.

Skin moisture per hour division Comparative Prescription 3 Prescription Example 1 Prescription Example 2 Before application 52.8 51.4 53.5 2 hours later 90.1 106.8 94.8 4 hours later 89.3 96.3 81.1 After 8 hours 74.5 77.4 69.2

As shown in Table 4, after applying the cosmetic preparation prepared according to Comparative Prescription Example 3, Prescription Example 1, Prescription Example 2, the skin immediately before and after 2, 4 and 8 hours after application, respectively As a result of measuring the moisture content, the moisturizing power of Formulation Examples 1 and 2 containing the acyl taurate-based anionic surfactant as an active ingredient of the present invention was almost moisturizing similar to Comparative Formula 3 of conventional nonionic surfactant-containing cosmetics. In particular, it was found to be much superior to the conventional cosmetics in the moisturizing power for a short time within 2 hours. This is because the cream film formed by the clouding effect has an effect of increasing the initial moisturizing power of Formulations 1 and 2, and the interstitial interstitial components such as ceramide and cholesterol contained in Formulations 1 and 3, supplement the skin barrier. As it has the effect of lowering the transdermal moisture loss, the moisturizing sustainability is maintained, and thus the moisturizing effect of the cosmetics including acyl taurate anionic surfactants, ceramides and cholesterol, which are the active ingredients of the present invention, is the best. Could.

Experimental Example 4: Skin Irritation Experiment

Comparative Example 3 of Formulation Example 2 and Formulation Example 1 of the cosmetics in the closed patch test method was applied for 24 hours and then removed to measure the degree of skin irritation. As a criterion of determination, the relative comparison value was expressed as 0 for no skin irritation and 9 for severe cases. The results are shown in Table 5.

Skin irritation test result product Skin irritation degree product Skin irritation degree Comparative Prescription 3 0.14 Prescription Example 1 0.20

As can be seen from the skin stimulation test results of Table 5, both the Comparative Formula 3 and Formulation 1 cosmetic composition was confirmed that the degree of skin irritation is very low.

Although specific embodiments are listed as above, it is apparent to those skilled in the art that these specific techniques are merely preferred embodiments, and thus the scope of the present invention is not limited thereto. Accordingly, the actual scope of the present invention will be defined by the appended claims and their equivalents.

1 is an active ingredient acyl taurate anionic surfactant, higher fatty alcohols, ceramides, cosmetics containing cholesterol (prescription example 1) and cosmetics (prescription example 2) and prescription in ceramides and cholesterol in Prescription 1 In the formulation of Example 1, the cosmetics containing no acyl taurate anionic surfactant (Comparative Example 1), the cosmetics containing no higher fatty alcohol in the formulation of Formula 1 (Comparative Example 2), the formulation of Formula 1 Is a comparative photograph confirming the degree of turbidity of the cosmetic (Comparative Example 3) containing a nonionic surfactant instead of an acyl taurate anionic surfactant.

Claims (9)

At least one acyl taurate anionic surfactant selected from the group consisting of sodium methyl cocoyl taurate, sodium methyl lauroyl taurate, and sodium methyl myristoyl taurate and One or more higher fatty alcohols selected from the group consisting of cetyl alcohol, stearyl alcohol, cetostearyl alcohol and behenyl alcohol, Cosmetic composition which has a change in the property which temporarily produces a cloudy phenomenon. According to claim 1, wherein the content of the acyl taurate anionic surfactant based on the total weight of the cosmetic composition is 0.1 to 10.0% by weight, the cosmetic composition, characterized in that the content of the higher fatty alcohol is 0.5 to 15.0% by weight. According to claim 1, wherein the cosmetic composition is cholesterol, cholesteryl alkylate, cholesteryl glutamate, phytosteryl stearate, phytosteryl alkylate and phytosteryl glutamate selected from the group consisting of one cholesterol, polyol, A cosmetic composition further comprising lecithin and ceramide. The cosmetic composition according to any one of claims 1 to 3, wherein the cosmetic is for moisturizing the skin. delete delete delete delete delete

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