KR101123137B1 - manufacturing method of Composition of 2-layer - Google Patents

Abstract

The present invention relates to a method for producing a two-layered lotion to form a polar oil in the upper layer of the water phase, and after mixing the polar oil in a mixture of water-soluble polymers and purified water having a suitable dispersing power without containing a surfactant, The present invention relates to a method for producing a two-layered lotion having low irritation to the skin and excellent skin absorption and moisturizing effect by stably floating the oil on the upper layer after passing through the aqueous phase containing a moisturizing agent.

Polar oil, water-soluble polymer, surfactant-free, two-layered, lotion

Description

Manufacturing method of Composition of 2-layer

The present invention relates to a method for producing a separable two-layered lotion containing a polar oil in the upper layer, and more particularly, to stabilize the oil in the upper layer by passing a high-pressure homo group using a water-soluble polymer that does not contain a surfactant and has a suitable dispersibility. The present invention relates to a method for preparing a two-layered lotion having excellent stability, less irritation to the skin, and excellent skin absorption and moisturizing effects.

In general, the lotion is formed of a single-phase lotion whose main component is water and water-soluble ethanol, and a small amount of fragrances or oils, which are poorly soluble in water, in the water using a surfactant.

The conventional lotion has a function of simply imparting a skin converging effect and a skin cleaning effect by the action of ethanol and various moisturizing ingredients contained while remaining on the outermost layer of the stratum corneum when applied to the skin. In addition, moisturizers (eg glycerin, 1,3-butylene glycol, propylene glycol, polyoxyethylenes, etc.) and high molecular substances (ie, hydroxyethyl cellulose, hydroxy) which give moisturizing and softening effects in the lotion Propyl methyl cellulose, xanthan gum, pectin, locust bean gum, sodium alginate, mucopolysaccharides, and the like) are water-soluble and thus have limitations in improving the flexibility and softness of the lotion. The amount of oil can be increased to solve this problem, but it is undesirable because it must again use a large amount of surfactant to solubilize and cause skin irritation.

The solution developed to solve this problem is to use a relatively large amount of oil in the form of suspending skin, but to disperse the oil stably with an appropriate amount of surfactant without using a large amount of surfactant to solubilize the oil. A single phase lotion that is almost opaque. In this way, it increases skin flexibility, moist feeling and softness, which helps to improve the feeling, but the oil used is limited to a few such as esters which are completely dissolved in ethanol, short chain triglycerides, tocopherol acetate, and phenylmethicone oils. Surfactant is not applicable to various applications such as using polyoxyethylene hardened castor oil, and when the amount of oil used is increased or the suspension is increased, aggregation between particles occurs and the particle size is gradually increased, so that the oily component is gathered to the upper layer. Separation may occur, and there are various limitations, such as problems in stability.

On the other hand, a method of applying a large amount of oil to the lotion while improving the stability of the particles is a method using a micro emulsion. Microemulsions are made by adding nonionic surfactants and oils in a constant ratio or by adding anionic surfactants and weak electrolytes. When the appropriate amount of the emulsion is added to the lotion, a semi-transparent lotion form is formed, and by forming fine particles, a relatively large amount of oil can be stably applied. However, these micro-emulsions are made only when the content ratio of the surfactant and oil is almost constant, so the high surfactant content may cause skin irritation, and when added to the lotion, there is a problem that separation occurs due to aggregation between particles according to the change over time. have.

Accordingly, the present invention was devised to solve the above-mentioned problems, and an object of the present invention is to contain a surfactant and stably float polar oil on the upper layer to form a lotion in two layers to increase product stability. To improve skin safety and enhance skin flexibility, skin penetration and moisturizing effects.

In order to solve the above problems, the present invention may include the following means.

Method for producing a two-layer cosmetic lotion according to an embodiment of the present invention, the water phase component forming step of forming a water phase component, and the polar oil is to prepare an oil phase component formed on the upper layer of the water phase component prepared in the water phase component forming step It includes an oil phase component forming step, the oil phase component forming step, the dispersion step of dispersing the water-soluble polymer in purified water, and the polar oil mixing step of mixing the polar oil in a solution by dispersing the water-soluble polymer in the purified water in the dispersion step In addition, the water-soluble polymer, sodium carbomer, carboxyvinyl polymer, acrylic acid polymer, xanthan gum, gellan gum, hyaluronic acid, guar gum, locust bean gum, queen's seed, carrageenan, gum arabic, pectin, mannan, starch, Alginate, Hydroxyethyl Cellulose, Hydroxyethyl Cellulose, Hydroxypropyl Methyl Cellulose, Secyl Hydroxyethyl Cell It is formed of one or more selected from cellulose, sodium carboxymethyl cellulose, alkylated cellulose having 2 to 20 carbon atoms, the polar oil is jojoba oil, soybean oil, sunflower seed oil, macadamia nut oil, Olive oil, hot oil, meadowfoam seed oil, grape seed oil, avocado oil, golden palm oil, isopropyl myristate, cetylethylhexanoate, isopropyl isostearate, octyl dodecyl myristate, diisoste Arylmaleates, tocopheryl acetate, caprylic / capric triglycerides, caprylic / capric glycerides, triethylhexanoin, phenyltrimethicone, dimethicone and cyclomethicone silicone oils, ethoxy Rated alkyl ether oils, propoxylated alkyl ether oils, phytosphingosine, sphingosine, sphinginine, ceramides, cerebrosides, kohl Sterol, cytosterol, cholesteryl sulfate, cytosteryl sulfate, phosphatidylcholine, phosphadidylethanolamine, isostearic acid, isostaryl alcohol is formed by forming one or more components, the oil phase component is formed on the upper layer of the water phase component do.

According to another embodiment of the present invention, the oil phase component forming step, the polar oil particle size is formed to 50 ~ 100nm to prevent the aggregation of the polar oil particles and to be evenly distributed and the oil particles are attached to the container wall It is characterized in that it further comprises a nanonization step to prevent it.

According to another embodiment of the present invention, the nanonization step is characterized in that the solution mixed in the polar oil mixing step is formed by passing a high pressure homomolecular pressure of 600 ~ 1200bar.

According to another embodiment of the present invention, the method of manufacturing the two-layered lotion is characterized in that it further comprises a stirring step of mixing the oil phase component formed in the nano-phase step to the water phase component formed in the water phase component forming step.

According to another embodiment of the present invention, the water phase component forming step further comprises a moisturizing agent in the water phase component of purified water, the moisturizing agent, propylene glycol, dipropylene glycol, 1,3-butylene glycol Lycol, glycerin, methylpropanediol, isopreneglycol, erythritol, xylitol, sorbitol, maltitol, betaine, arginine, proline, glucose, sucrose, trehalose, raffinose, polyoxyethylene, sodium pyridonecarboxylic acid, lactic acid It is characterized in that it is formed of one or more components selected from sodium.

The present invention does not contain a surfactant and at the same time stably float the polar oil on the upper layer to form a lotion in two layers to enhance product stability and improve skin safety and to improve skin flexibility, skin penetration and moisturizing effect. It is to plan the effect.

Hereinafter, the present invention will be described in detail.

1 is a block diagram of a manufacturing method according to an embodiment of the present invention.

Referring to Figure 1, the two-layer cosmetic lotion manufacturing method according to the present invention may include a water phase component forming step (S1), oil phase component forming step (S2), stirring step (S3).

The water phase component forming step (S1) according to the present invention is a variety of additives commonly used in the cosmetic field in purified water, for example, sunscreen, antioxidants, liquid fats, solid fats, lead oils, ester oils, hydrocarbon oils, silicone resins, A step of forming an aqueous phase by adding a lower alcohol, a sterol, a water-soluble polymer, a metal ion sequestering agent, a neutralizing agent, a pH adjusting agent, an antimicrobial agent, a fragrance, a coloring matter, etc., but preferably containing a moisturizing agent component in purified water as an active ingredient. Preferably, the purified water is contained in an amount of 10 to 90% by weight based on the total weight of the aqueous phase component, and the moisturizing component is contained in an amount of 2.0 to 50% by weight based on the total weight of the aqueous phase component.

The moisturizing component used as an active ingredient in the water phase ingredient forming step (S1) is propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin, methylpropanediol, isoprene glycol, erythritol, Polyols such as xylitol, sorbitol, maltitol, amino acids such as betaine, arginine, and proline, and at least one selected from sugars such as glucose, sucrose, trehalose, and raffinose, polyoxyethylene, sodium pyridone carbonate, and sodium lactate The component may be used, but is not limited thereto, and includes a moisturizer component commonly used in the cosmetic field, and the amount thereof is preferably 2.0 to 50% by weight, preferably 4.0 to 20% by weight.

The oil phase component forming step (S2) is a step of preparing an oil phase component for the polar oil to be formed on the upper layer of the water phase component prepared in the water phase component forming step (S1), the dispersion step (S21), polar oil mixing step ( S22), may include a nanonization step (S23).

The dispersing step (S21) is a step of dispersing the water-soluble polymer in purified water, wherein the purified water is 2.0 to 50% by weight relative to the total weight of the oil phase component, the water-soluble polymer is formed to 0.001 to 10% by weight relative to the total weight of the oil phase component It is preferable.

On the other hand, the water-soluble polymer used as an active ingredient in the present invention may use a variety of components commonly used in the cosmetic industry, preferably, sodium carbomer, carboxyvinyl polymer, acrylic acid polymer, xanthan gum, gellan gum, Hyaluronic acid, guar gum, locust bean gum, queen's seed, carrageenan, gum arabic, pectin, mannan, starch, alginate, hydroxyethyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, At least one component selected from alkylated cellulose having 2 to 20 carbon atoms, such as cellulose and sodium carboxymethyl cellulose, may be used, and the amount thereof is used in the total weight of the oil phase component prepared in the oil phase component forming step (S2). It is suitable to mix | blend with 0.001-10 weight% with respect to 0.01-5.0 weight% preferably. By the water-soluble polymer in the nanonization step (S23) to be described below, the polarized oil particles can be caught without a surfactant, without the surfactant, it gives the effect of skin flexibility.

The polar oil mixing step (S22) is a step of mixing polar oil in a solution in which the water-soluble polymer is dispersed and dissolved in purified water in the dispersing step, and the nonpolar oil is not included in the present invention because it does not continuously maintain the stability of the final product. .

On the other hand, the polar oil used as an active ingredient in the present invention can use a variety of components commonly used in the cosmetic industry, preferably, jojoba oil, soybean oil, sunflower seed oil, macadamia nut oil, olive oil , Vegetable oils such as oil, meadowfoam seed oil, grape seed oil, avocado oil, golden palm oil, isopropyl myristate, cetylethylhexanoate, isopropyl isostearate, octyldodecyl myristate, di Synthetic oils such as isostearyl maleate, tocopheryl acetate, glyceride synthetic oils such as caprylic / capric triglycerides, caprylic / capric glycerides, triethyl hexanoin, and phenyltrimethicone , Dimethicone and cyclomethicone silicone oils, ethoxylated alkyl ether oils, propoxylated alkyl ether oils, p Sphingoid lipids such as sphingosine, sphingosine, sphinginine, ceramides, cerebrose, cholesterol, cytosterol, cholesteryl sulfate, cytosteryl sulfate, phosphatidylcholine, phosphadidylethanolamine, isostearic acid, iso One or more components selected from stearyl alcohol may be used, and the amount used may be 0.05 to 20% by weight, preferably 0.2 to 10% by weight, based on the total weight of the oily components prepared in the oil phase component forming step (S2). Suitable. On the other hand, the non-polar oil is excluded from the present invention because the two-layered lotion prepared by the present invention does not exert sufficient effect in maintaining stability in two layers.

The nanonization step (S23) is a step of forming an oil phase having an oil particle size of 50 ~ 100nm dispersed in the oil phase passed through the polar oil mixing step (S22), the method of nano-sizing the oil particle size can be various. However, preferably the solution mixed in the polar oil mixing step (S22) is passed through a high pressure homogenizer under a constant pressure, preferably a pressure of about 600 ~ 1200bar. The number of passes may be adjusted to 1 to 5 times to form an oil phase component so that the size of the oil particles dispersed in the solution passed through the polar oil mixing step (S22) to 50 ~ 100nm. Nano-scaled oil particle size prevents oil particles from agglomerating and distributes evenly and prevents oil particles from adhering to the container walls.

The stirring step (S3) may be mixed by a variety of methods known as the step of mixing the oil phase formed in the nanonization step (S23) to the water phase formed in the water-phase powder forming step (S1) and mixing.

The two-layered cosmetic preparation method according to the present invention may further include a mixing step (S4), the mixing step (S4) is an ethanol, fragrance, preservative according to the needs of the manufacturer in the oil phase formed in the stirring step (S3) It is a step of mixing by adding an appropriate amount and the like.

If left still after the stirring step (S3) or mixing step (S4), a two-layered lotion is formed.

As a result, the present invention does not contain a surfactant and stably floats polar emollient oil on the upper layer to form a lotion in two layers, thereby improving product stability, improving skin safety, and improving skin flexibility, skin penetration and moisturizing effect. You can do it.

To explain the manufacturing process in more detail, disperse and dissolve 0.001-10 wt% of water-soluble polymer in 1.0-30 wt% of purified water, preferably 3.0-20 wt%, mix and mix 0.1-20 wt% of polar oil, and then press Pass the mosquitoes under 600 ~ 1200 bar pressure. The number of passes is prepared by arbitrarily adjusting 1 to 5 times to form a finely dispersed oil particle size of 50 ~ 100nm when shaking the two layers in the final product. The oil phase thus made is added to an aqueous phase containing various moisturizers, and if necessary, ethanol, fragrance, and preservatives are additionally mixed, mixed lightly, and left to stand so that the oil component rises to the upper layer. Hereinafter, the content of the present invention will be described in more detail with reference to Examples and Comparative Examples of the present invention.

Example: Preparation of Two-Layered Lotion

 Composition and Example of Two-Layered Lotion (Unit: Weight%) Prize ingredient Example-1 Example-2 Example-3 Example-4 Example-5 A Purified water To.100 To.100 To.100 To.100 To.100 1,3-butylene glycol 3.00 3.00 3.00 3.00 3.00 glycerin 3.00 3.00 3.00 3.00 3.00 DL-Panthenol 0.20 0.20 0.20 0.20 0.20 IDT-2Na 0.02 0.02 0.02 0.02 0.02 B Purified water 3.00 3.00 3.00 3.00 3.00 Sodium carbomer 0.10 - - - - Xanthan gum - 0.10 - - - Alginate - - 0.10 - - Sodium Carboxymethyl Cellulose - - - 0.10 - Secyl Hydroxyethyl Cellulose - - - - 0.10 C Caprylic / Capric
Triglycerides 2.00 - - - - 3,7 hexanoate - 2.00 - - - Soybean Oil - - 2.00 - 1.70 Phenyl trimecicone - - - 2.00 - Tocopheryl acetate - - - - 0.30 D ethanol 3.00 3.00 3.00 3.00 3.00 incense Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount antiseptic Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount

<Manufacturing process>

1. Mix A phase, dissolve it cleanly, and make water phase.

2. Add water-soluble polymer to purified water in phase B, mix and dissolve. If necessary, warm the purified water to 50 ~ 60 ℃ so that the water-soluble polymer can be dissolved cleanly.

3. Add phase C to phase B and stir appropriately. When the solid component is added to the C phase, it is heated, dissolved and mixed uniformly before being added to the B phase.

4. The mixed BC phase is passed through the high pressure homogenizer 2 to 4 times under the condition of 600 ~ 1,000bar and cooled to make an oil phase having oil particle size of 50 ~ 100nm.

5. Add the high pressure BC phase to phase A and mix properly.

6. Add phase D, stir the mixture, and then settle to float the oil to prepare Examples 1 to 5, which is a two-layered lotion without oil surfactant and nanoparticles.

Comparative Example: Preparation of Single Phase Suspension Cosmetics

Composition and Comparative Example of Suspended Toilet Water Prize ingredient Comparative Example-1 Comparative Example-2 A Purified water To.100 To.100 1,3-butylene glycol 3.00 3.00 glycerin 3.00 3.00 DL-Panthenol 0.20 0.20 IDT-2Na 0.02 0.02 B Purified water 3.00 3.00 Sodium carbomer 0.10 - Secyl Hydroxyethyl Cellulose - 0.10 C ethanol 3.00 3.00 Caprylic / Capric
Triglycerides 2.00 - Soybean Oil - 1.70 Tocopheryl acetate - 0.30 Fiji-60 Hydrogenated Castor Oil 1.00 1.00 incense Suitable amount Suitable amount antiseptic Suitable amount Suitable amount

<Manufacturing process>

1. Mix Phase A and dissolve it cleanly.

2. Add water-soluble polymer to purified water in phase B, mix and dissolve, and mix by adding into phase A. If necessary, warm the purified water to 50 ~ 60 ℃ so that the water-soluble polymer can be dissolved cleanly.

3. Dispersion of PIG-60 hydrogenated castor oil, which is a surfactant, in ethanol C, and the components shown in Table 2 above, followed by gradually mixing with AB, followed by Comparative Examples 1 and 2, which are suspensions containing a single phase containing surfactant. Manufacture.

Experimental Example 1: Measurement of Product Stability

1. Experimental Product:

Examples 1 to 5 two-layered lotion containing nanonized oil

Comparative Examples 1 and 2: Suspension Cosmetics Containing Previous Oil and Surfactant

2. Experiment Method:

1) First, the particle sizes of Examples 1 to 5 and Comparative Examples 1 and 2 were determined by measuring ZETASIZER Nano-ZS (MALVERN) at 45 ° C. for 28 days at a daily interval. Examples 1 to 5 were shaken and mixed, and then allowed to stand again to measure the size of particles present.

Particle size of lotion Example 1 Example 2 Example 3 Example 4 Example 5 Comparative Example 1 Comparative Example 2 Average particle
size
(nm, 45 ℃) Early 72.5 76.2 78.6 82.1 83.4 251.3 475.2 7 days 72.8 76.3 78.9 82.5 83.6 283.4 492.3 14 days 73.1 76.6 79.2 82.5 83.7 324.6 581.2 21st 73.3 76.8 79.3 82.8 84.1 361.5 720.4 28 days 73.7 77.2 79.6 83.2 84.6 450.2 928.6

2) Each product was put in the same amount in a transparent test bottle (choja) and the relative stability was checked by checking the stability status of the product for 28 days at 45 ° C for 1 day. The experimental results are shown in Table 4 below.

Product stability test results product Stability Examples 1-5 Stable up to 28 days Comparative Example 1 Separation starts on day 21 Comparative Example 2 Separation Begins on Day 14

As shown in <Table 3>, the particle size of the present invention is almost constant even on the 28th day, and as shown in <Table 4>, the stability is excellent even without the change of big properties on the 28th day. It can be predicted that it will not occur and will be evenly distributed and will not stick to the wall of the cosmetic container so as not to spoil the beauty of the use.

Experimental Example 2 Skin Moisturizing Effect Experiment

1. Experimental product: same as Experimental Example 1

2. Test Method:

After dividing 20 healthy women into two groups A and B in a room with 25 ° C, 45% relative humidity, and no air flow, Group A is Example 1 and Comparative Example 1, and Group B is Example 5 and Comparative Example. 2 was applied to the upper arm of the arm twice a day for 6 weeks, and then the TEWL change (△ TEWL) with time was measured using a Tewameter TM 210 (C + K Electonic GmbH). The moisturizing effect was measured by quantifying the moisture content of the skin from 0 to 150 using the CM 820 PC (C + K Electronic GmbH) according to the change in the electrical conductivity according to the epidermal moisture content. The measurement results are shown in Table 5 below.

Skin moisturizing effect result product △ TEWL (g / hm ² ) Corneometer value Example 1 6.5 128 Comparative Example 2 1.5 78 Example 5 7.2 136 Comparative Example 2 2.4 85

As a result, the embodiment of the present invention shows an excellent moisturizing effect than the comparative example, which can be seen that the present invention increases the skin moisturizing power by increasing the skin absorption and retention of the moisturizing component.

Experimental Example 3: Skin Irritation Experiment

1. Experimental product: same as Experimental Example 1

2. Experiment Method:

The product was attached for 24 hours by a closed patch test method and then removed to check the degree of skin irritation. As a criterion of determination, the relative comparison value was expressed as 0 for no skin irritation and 5 for severe cases. The experimental results are shown in Table 6.

Skin irritation test result product Skin irritation degree Example 1 0.8 Comparative Example 1 2.6 Example 5 0.6 Comparative Example 2 2.4

In Table 6, the embodiment of the present invention has a significantly lower irritation value compared to the comparative example, which indicates that the skin irritation is reduced compared to the suspension skin containing a large amount of surfactant because the present invention does not contain a surfactant.

Experimental Example 4: Product Sensory Experiment

1. Experimental product: same as Experimental Example 1

2. Experiment Method:

After dividing 20 women in their 20s and 30s into two groups A and B, group A used Example 1 and Comparative Example 1, and group B used Example 5 and Comparative Example 2 on the left and right sides of the subject every morning, Two evenings were used twice each evening for skin softness, moistness, stickiness, spreadability, and absorbency. The relative value was checked as 5 for the best case and 0 for the worst case. The experimental results are shown in Table 7 below.

Sensory test results of the product product flexibility Moist No stickiness Spreadability Absorbent Example 1 4.0 4.5 4.5 4.0 4.5 Comparative Example 1 3.0 3.0 3.5 3.0 3.5 Example 5 4.5 5.0 4.5 4.0 5.0 Comparative Example 2 3.0 3.5 2.0 2.0 3.0

As shown in Table 7, the examples of the present invention showed overall excellent results in the sensory experiments compared to the comparative examples, and in particular, the skin absorption of the nanonized oil was good and the moisture improving effect was excellent.

1 is a block diagram of a manufacturing method according to an embodiment of the present invention.

Claims (5)

An aqueous phase forming step of forming an aqueous phase component, Polar oil comprises an oil phase component forming step for producing an oil phase component formed on the upper layer of the water phase component prepared in the water phase component forming step, The oil phase component forming step, A dispersion step of dispersing the water-soluble polymer in purified water; Further comprising a polar oil mixing step of mixing the polar oil in a solution by dispersing the water-soluble polymer in purified water in the dispersing step, The water-soluble polymer, Sodium carbomer, carboxyvinyl polymer, acrylic acid polymer, xanthan gum, gellan gum, hyaluronic acid, guar gum, locust bean gum, queen's seed, carrageenan, gum arabic, pectin, mannan, starch, alginate, hydroxyethyl cellulose, hydroxy It is formed of at least one selected from hydroxyethyl cellulose, hydroxypropyl methyl cellulose, methyl hydroxyethyl cellulose, sodium carboxymethyl cellulose, alkylated cellulose having 2 to 20 carbon atoms, The polar oil is, Jojoba oil, soybean oil, sunflower seed oil, macadamia nut oil, olive oil, hot dip oil, meadowfoam seed oil, grape seed oil, avocado oil, golden palm oil, isopropyl myristate, cetylethylhexanoate, Isopropylisostearate, octyldode silmyristate, diisostearyl maleate, tocopheryl acetate, caprylic / capric triglycerides, caprylic / capric glycerides, triethylhexanoin, phenyltri Methicone, dimethicone and cyclomethicone type silicone oils, ethoxylated alkylether based oils, propoxylated alkylether based oils, phytosphingosine, sphingosine, sphinginine, ceramides, cerebrose, Cholesterol, Sitosterol, Cholesteryl Sulfate, Sitosteryl Sulfate, Phosphatidylcholine, Phosphadylethanolamine, Isostearic Acid, Isostearyl Alcohol Is formed with one or more components selected from, A method for producing a two-layered lotion without including a surfactant so that an oil phase component is formed on the upper layer of the water phase component. According to claim 1, wherein the oil phase component forming step, Method for producing a two-layered cosmetic lotion, characterized in that it further comprises a nanonizing step of granulating the polar oil present in the solution mixed in the polar oil mixing step to a nano size of 50 ~ 100nm. The method of claim 2, wherein the nanonization step, Method of producing a two-layered lotion, characterized in that formed by passing the solution mixed in the polar oil mixing step of a high pressure homo-molecule of 600 ~ 1200bar pressure. The method of claim 2, wherein the two-layered lotion Method for producing a two-layered cosmetic lotion, characterized in that it further comprises a stirring step of mixing the oil phase component formed in the nano-ization step to the water phase component formed in the water phase component forming step. According to claim 1, wherein the water phase component forming step, A moisturizer is additionally included in the aqueous phase of purified water; The moisturizing agent, Propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin, methylpropanediol, isoprene glycol, erythritol, xylitol, sorbitol, maltitol, betaine, arginine, proline, glucose, sucrose , Trehalose, raffinose, polyoxyethylene, sodium pyrrolidone carbonate, sodium lactate, the method for producing a two-layered lotion, characterized in that formed from one or more components.

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