KR100501341B1 - Novel Opacifier and Cosmetic Composition Comprising the Same - Google Patents

Abstract

The present invention relates to an opacifying agent consisting of nano-vesicles and a cosmetic composition comprising the same, more specifically, 5.0-50.0 wt% of an oil component, 20.0-80.0 wt% of a polyol, 0.1-10.0% of a surfactant, and 0.5-20.0 wt of a phospholipid. %, Fatty acid 0.05-3.0% by weight and purified water 2.0-30.0% by weight, the nanovesicle opaque agent characterized in that the fatty acid is not used when the surfactant is an anionic surfactant containing a higher fatty acid And it relates to a cosmetic composition comprising the same.

Description

Novel Opacifier and Cosmetic Composition Comprising the Same

The present invention relates to a novel opacifying agent and a cosmetic composition comprising the same, and more particularly to an opacifying agent consisting of nano-vesicles and a cosmetic composition comprising the same.

According to the prior art, the opacifying agents (suspensions) used in skin lotions, essences, packs, shampoos, body cleansers and hair brushing lotions are styrene / acrylate copolymers, styrene / acrylamide copolymers, ethylene glycol monostearates. And ethylene glycol distearate, zinc stearate, guanine pearl, and microemulsions containing dimethicone, esters, animal and vegetable oils and mineral oils. Specific examples of styrene / acrylate copolymers and styrene / acrylamide copolymers include sodium styrene / acrylate / PEG-10 dimaleate copolymer and ammonium nonoxynol-4 sulfate, styrene / acrylate copolymer and octoxy Nol-9 and sodium dodecylbenzenesulfonate.

Skin lotions, essences, and packs are particularly suitable for ethanol, short-chain triglycerides and phenylmethicone oils. PEG-60 hydrogenated castor oil and PEG-40 hydrogenated. A mixture obtained by adding and dissolving a surfactant such as castor oil to a dissolved ethanol solution is used as an opacifying agent.

The characteristics of the opacifiers used in the past are styrene / acrylate copolymers, styrene / acrylamide copolymers, zinc stearate, guanine pearls, etc., but the opacity and spreadability of the products containing them Poor hand movement, poor flexibility, lack of moisturizing and moisturizing, so that there is a problem to dry and rough skin, which does not help improve the usability at all, and eventually settles down with changes over time shows a problem in long-term stability.

Ethylene glycol monostearate, ethylene glycol distearate, etc., have a pearl appearance in shampoos, body cleansers, and detergents to increase the appearance of the appearance while increasing the gloss and softness of the hair as a refatting agent. Along with the change, agglomeration occurs between the opacifier particles and the particle size is increased as a whole, resulting in separation and a change in the appearance of the product.

Michaelo emulsions containing various oils improve the softness, softness, spreadability and spread of the skin, and improve the gloss, softness and combability of the hair.However, there is a problem that separation occurs due to aggregation between the particles according to the change over time. In particular, in order to form the microemulsion, the concentration of the surfactant must be higher than that of the general emulsion. High concentrations of surfactants can cause skin irritation, and the frequency of products using microemulsions in this dimension tends to decrease.

Opaque agents using ethanol mixtures containing oils, oily ingredients, and surfactants that dissolve in ethanol will help improve the skin's flexibility, moistness, and softness, thereby improving the feeling of use. There is a problem in that the particle size is gradually increased and oily components are collected in the upper layer, the separation occurs.

The present inventors have diligently researched to solve the problems of the conventional opacifying agent, and as a result, the cosmetic composition including the nano-vesicle made of specific ingredients is not only excellent in feeling and stability, but also shows a moisturizing effect and irritation to the skin. It was confirmed that the degree is very small and came to complete the present invention.

Accordingly, it is an object of the present invention to provide an opaque agent consisting of nanovesicles.

Another object of the present invention to provide a cosmetic composition comprising an opacifying agent consisting of nano-vesicles.

Other objects and advantages of the present invention will become apparent from the following detailed description and claims.

According to one aspect of the invention, the present invention is 5.0-50.0% by weight of oil component, 20.0-80.0% by weight polyol, 0.1-10.0% surfactant, 0.5-20.0% phospholipid, 0.05-3.0% fatty acid and purified water 2.0- It comprises 30.0% by weight, and when the surfactant is an anionic surfactant containing a higher fatty acid provides a nano-vesicle opaque agent, characterized in that the fatty acid is not used.

As used herein, the term "nanovesicle" refers to a vesicle structure with a nanounit size and is distinguished from a nanoliposome with a lipid bilayer in that it is surrounded by a lipid monolayer. On the other hand, the term "nanocifier" as used herein refers to an opacity (opacifier) having a nano unit size, it is an acronym made by the inventors.

The size of the nanovesicles of the present invention has an average particle diameter of 10-100 nm, preferably 30-70 nm. When the average particle diameter of the nanovesicle exceeds 70 nm, the technical effect to be achieved in the present invention, that is, the improvement of the usability and stability is very weak.

The oil component used in the preparation of the nanovesicle of the present invention may be a variety of oils known in the art, preferably hydrocarbon-based oils such as hexadecane and paraffin oil; Synthetic synthetic oils; Silicone oils such as dimethicone and cyclomethicone series; Animal and vegetable oils such as sunflower oil, corn oil, soybean oil, avocado oil, sesame oil and fish oil; Ethoxylated alkyl ether oils; Propoxylated alkyl ether oils; Sphingoidoid lipids such as phytosphingosine, sphingosine and sphinginine; Ceramides; Cerebroside; cholesterol; Cytosterol; Cholesteryl sulfate; Cytosteryl sulfate; C _10-40 fatty alcohol or C _10-40 fatty acid. The amount used is 5.0-50.0% by weight, preferably 10.0-30.0% by weight, based on the total weight of the nanovesicle.

The polyol which is another component used in the preparation of the nanovesicle of the present invention is not particularly limited, and preferably, propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin, methyl propanediol, isoprene glycol, pen It is selected from the group consisting of styrene glycol, erythritol, ziitol and sorbitol. The amount used is 20.0-80.0% by weight, preferably 30.0-70.0% by weight, based on the total weight of the nanovesicle.

The surfactant used in the present invention may use any known in the art, for example, anionic surfactants, cationic surfactants, amphoteric surfactants and nonionic surfactants may be used, preferably anions Aqueous surfactants and nonionic surfactants are used. Specific examples of anionic surfactants include alkylacylglutamate, alkylphosphates, alkyllactylates, dialkylphosphates and trialkylphosphates. Specific examples of nonionic surfactants include alkoxylated alkyl ethers, alkoxylated alkyl esters, alkylpolyglycosides, polyglyceryl esters and sugar esters. Most preferably, alkyl lactylates belonging to the anionic surfactant or polysorbates belonging to the nonionic surfactant are used. On the other hand, in the preparation of the nanovesicles of the present invention, when anionic surfactants containing higher fatty acids (eg, sodium stearoyl lactylate) are used, the necessity for fatty acids required for nanovesicle preparation is eliminated. Can be. The amount of the surfactant is generally 0.1-10.0% by weight, preferably 0.5-3.0% by weight based on the total weight of the nanovesicle.

Phospholipids, another component used in the preparation of the nanovesicles of the present invention, are used as amphoteric lipids, including natural phospholipids (eg, egg yolk lecithin or soy lecithin, sphingomyelin) and synthetic phospholipids (eg, dipalmi Toilphosphatidylcholine or hydrogenated lecithin), preferably lecithin. More preferably, the lecithin is naturally occurring unsaturated lecithin or saturated lecithin extracted from soybean or egg yolk. Typically, lecithin derived from nature has 23-95% phosphatidyl choline and 20% or less phosphadidylethanolamine. The amount of phospholipid used is 0.5-20.0% by weight based on the total weight of nanovesicles, preferably 2.0-6.0% by weight.

The fatty acids used in the production of nanovesicles of the present invention are higher fatty acids, preferably saturated or unsaturated fatty acids of C _12-22 alkyl chains such as lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid and Linoleic acid. The amount used is 0.05-3.0% by weight based on the total nanovesicle weight, preferably 0.1-1.0% by weight.

The water used in the present invention is deionized distilled water, the amount of which is used 2.0-30.0% by weight, preferably 5.0-20.0% by weight.

The preparation of nanovesicles may be accomplished through various methods known in the art, but most preferably, a mixture comprising the above components is applied to a high pressure homogenizer. The production of nanovesicles by high pressure homogenizer can be carried out under various conditions (eg pressure, frequency, etc.) depending on the desired particle size, preferably 1-5 times high pressure homogenizer under 600-1200 bar pressure. The nanovesicles are made by passing through the Niger.

According to another aspect of the present invention, the present invention provides a cosmetic composition comprising the nanovesicle opacifier.

The content of the nanovesicle opacifying agent in the cosmetic composition may vary depending on the desired suspension, but is generally 0.1-30.0% by weight, preferably 1.0-20.0% by weight.

The cosmetic composition of the present invention may be prepared in any formulation commonly prepared in the art, for example, solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, surfactant-containing cleansing , Oils, powder foundations, emulsion foundations, wax foundations and sprays, and the like, but are not limited thereto. More specifically, it may be prepared in the form of softener, essence, pack, shampoo, body cleanser, hair lotion or detergent.

When the formulation of the present invention is a paste, cream or gel, animal oils, vegetable oils, waxes, paraffins, starches, trachants, cellulose derivatives, polyethylene glycols, silicones, bentonites, silicas, talc or zinc oxide may be used as carrier components. Can be.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used, in particular in the case of a spray, additionally chlorofluorohydrocarbon, propane Propellant such as butane or dimethyl ether.

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizer or emulsifier is used as the carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 Fatty acid esters of, 3-butylglycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan.

When the formulation of the present invention is a suspension, liquid carrier diluents such as water, ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, microcrystals Soluble cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

When the formulation of the present invention is a surfactant-containing cleansing, the carrier component is aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide. Ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives or ethoxylated glycerol fatty acid esters and the like can be used.

The nano-vesicle opacifier of the present invention is used in transparent products such as softener, essence, pack, shampoo, body cleanser, hair brushing lotion, cleanser, etc. to change the appearance of the product while controlling the transparency to improve aesthetic sense and value. It improves, increases skin moisturizing and flexibility, increases hair gloss and softness, and greatly improves the feel and storage stability.

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are only for illustrating the present invention in more detail, it is to those skilled in the art that the scope of the present invention is not limited by these examples in accordance with the gist of the present invention. Will be self-evident.

Preparation Example: Preparation of Nanosipifier

Components and Preparation Examples of Nanosipifiers Prize ingredient Production Example-1 Preparation Example-2 Preparation Example-3 Preparation Example-4 Preparation Example-5 Preparation Example-6 Preparation Example-7 Preparation Example-8 Preparation Example-9 Preparation Example-10 Preparation Example-11 A Propylene glycol 40.0 - - - - - - - - 60.0 - 1,3-butylene glycol - 45.0 - - - - - - - - - glycerin - - 50.0 50.0 50.0 50.0 50.0 50.0 - - 50.0 B lecithin 3.0 6.0 3.0 - - - 4.0 - - - - Hydrogenated Lecithin - - - 6.0 6.0 6.0 - 8.0 8.0 8.0 6.0 C Dimethicone (100cs) 15.0 - - - - - - - - - - Caprylic / Capric Triglycerides - 20.0 - - 15.0 15.0 15.0 - - - - Jojoba oil - - 15.0 - - - - 30.0 35.0 20.0 - Squalane - - - 20.0 - - - - - - - Tocopheryl Acetate - - - - - - - - - - 20.0 cholesterol - - - - 5.0 - 2.5 - - - - Ceramide - - - - - 5.0 2.5 - - - - D Sodium stearoyl lactylate 1.0 - - - 1.5 1.5 1.5 1.5 2.0 2.0 2.0 Polysorbate-80 - 1.5 1.5 1.5 - - - - - - - Stearic acid - 0.5 0.5 0.5 - - - - - - - E Purified water To.100 To.100 To.100 To.100 To.100 To.100 To.100 To.100 To.100 To.100 To.100 F Potassium hydroxide Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity

Phase B was added to phase A and wetted uniformly, then phases C, D, E and F were added onto AB and heated and mixed to 70-77 ° C. and stirred uniformly. Subsequently, the mixture was passed through a high-pressure homogenizer 1-5 times under conditions of 600-1,200 bar and cooled to prepare a nanovesicle having a particle size of 30-70 nm in diameter.

Examples 1-1, 1-2 and Comparative Example 1-4: Preparation of Flexible Lotion

Composition of flexible lotion ingredient Example 1-1 Example 1-2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Distilled water To. 100 To. 100 To. 100 To. 100 To. 100 To. 100 glycerin 3.0 3.0 3.0 3.0 3.0 3.0 1,3-butylene glycol 3.0 3.0 3.0 3.0 3.0 3.0 DL-panthenol 0.2 0.2 0.2 0.2 0.2 0.2 EDTA-2Na 0.02 0.02 0.02 0.02 0.02 0.02 Hyaluronic acid liquid 2.0 2.0 2.0 2.0 2.0 2.0 ethanol 7.0 7.0 7.0 7.0 7.0 7.0 PEG-60 Hydrogenated Castor Oil 0.6 0.6 0.6 0.6 0.6 0.6 Incense, preservative Quantity Quantity Quantity Quantity Quantity Quantity Preparation Example-11 5.0 10.0 - - - - Tocopheryl Acetate - - 0.8 1.6 - - Styrene / acrylamide copolymer / nonoxynol-35 - - - - 0.4 0.8

Experimental Example 1: Measurement of Product Stability

1. Experimental Product:

Examples 1-1 and 1-2: Product Added Nanoopathy Opaque Agent (Invention)

Comparative Examples 1 and 2: Products to Which Previous Opaque Agents were Added

Comparative Examples 3 and 4: Products to Which Previous Opaque Agents were Added

2. Experiment Method:

First, the suspension of Example 1-1, Comparative Examples 1 and 3 and the suspension of Example 1-2 and Comparative Examples 2 and 4 were confirmed by measuring the L value of the spectrophotometer (CM-3500d, MINOLTA). .

Suspension of flexible lotion product Suspension (L value) product Suspension (L value) Example 1-1 71.64 Example 1-2 48.73 Comparative Example 1 72.35 Comparative Example 3 48.21 Comparative Example 2 71.28 Comparative Example 4 47.65

Subsequently, the same amount of each product was put in a transparent test bottle (choja), and the relative stability was checked by checking the stability state of the product for 20 days at 45 ° C. per day. The experimental results are shown in Table 4 below.

Product stability test results product Stability Example 1-1 Stable up to 20 days Comparative Example 1 Separation Begins on Day 15 Comparative Example 3 Start of separation on day 10, complete separation on day 13 Example 1-2 Stable up to 20 days Comparative Example 2 Separation Begins on Day 7 Comparative Example 4 Separation starts on day 5

As can be seen in Table 4, it can be seen that the stability of the product using the opacifying agent of the present invention is very excellent because there is no separation at all without a great influence on the use concentration.

Experimental Example 2: Skin Moisturizing Effect Experiment

1. Experimental product: same as Experimental Example 1

2. Test Method:

After dividing 20 healthy women into two groups A and B at 25 ° C, 45% relative humidity and no air flow, Group A is Example 1-2 and Comparative Example 2, and Group B is Example 1-. 2 and Comparative Example 4 were applied to the upper arm of the arm three times a day for 6 weeks, and then the amount of TEWL changes with the change of TEWL (ΔTEWL) with time using Tewameter TM 210 (C + K Electonic GmbH). The moisturizing effect was measured by quantifying the moisture content of the skin from 0 to 150 with the change of electrical conductivity according to the moisture content of the epidermis using a coronometer CM 820 PC (C + K Electronic GmbH). The measurement results are shown in Table 5 below.

Skin moisturizing effect result product △ TEWL (g / hm ² ) Koniometer value Example 1-2 6.5 128 Comparative Example 2 3.3 112 Comparative Example 4 1.2 85

As a result, the product using the opacifying agent of the present invention shows a superior moisturizing effect than the previous opacifying agent, because the nanosipifier of the present invention increases the skin moisturizing power by reducing the transdermal moisture loss by strengthening the skin barrier. .

Experimental Example 3: Skin Irritation Experiment

1. Experimental product: same as Experimental Example 1

2. Experiment Method:

The product was attached for 24 hours by a closed patch test method and then removed to check the degree of skin irritation. As a criterion of determination, the relative comparison value was expressed as 0 for no skin irritation and 5 for severe cases. The experimental results are summarized in Table 6.

Skin irritation test result product Skin irritation degree product Skin irritation degree Example 1-1 0.8 Example 1-2 0.6 Comparative Example 1 1.6 Comparative Example 2 1.5 Comparative Example 3 3.6 Comparative Example 4 4.0

As can be seen in Table 6, the more the use of the nano-sapphire of the present invention appears to reduce the skin irritation, which increases the skin barrier strengthening effect is not easy to penetrate the skin of the external stimulation source is judged to be reduced skin irritation .

Experimental Example 4: Product Sensory Experiment

1. Experimental product: same as Experimental Example 1

2. Experiment Method:

After dividing 20 women in their 20s and 30s into two groups, A and B, group A was Example 1-2 and Comparative Example 2, and group B was Example 1-2 and Comparative Example 4. In the morning and evening, twice a week for 2 weeks, skin flexibility, moistness, stickiness, spreadability and absorbency were evaluated for the best case of 5 and the worst case of 0 to check relative comparison values. The experimental results are summarized in Table 7 below.

Sensory test results of the product product flexibility Moist No stickiness Spreadability Absorbency Example 1-2 5.0 5.0 4.0 4.0 5.0 Comparative Example 2 3.0 3.0 3.5 3.0 3.5 Comparative Example 4 1.0 0.5 3.0 1.0 1.0

As shown in Table 7, the cosmetic composition containing the nano-sapphire of the present invention has a very good performance in all parts of the sensory evaluation items, and significantly improved compared to the conventional cosmetic composition containing a conventional opacifying agent It can be seen that it shows a sensuality.

Hereinafter, as an example of the formulation of the present invention, a flexible lotion, an essence, a pack, a shampoo, a body cleanser, a hair gel, and a cleaning agent are exemplified, but the formulation of the cosmetic including the composition of the present invention is not limited thereto.

Formulation Example 1 Flexible Lotion

ingredient Formulation Example 1-1 (wt%) Formulation Example 1-2 (Weight%) Purified water To. 100 To. 100 glycerin 3.0 3.0 1,3-butylene glycol 3.0 3.0 DL-panthenol 0.2 0.2 EDTA-2Na 0.02 0.02 Sodium hyaluronate 2.0 2.0 ethanol 7.0 7.0 PEG-60 Hydrogenated Castor Oil 0.6 0.6 Preservative, incense Quantity Quantity Nano seafire-11 (production example-11) 5.0 - Nano seafire-4 (production example-4) - 10.0 Sum 100 100

Formulation Example 2: Essence

ingredient Formulation Example 2-1 (wt%) Formulation Example 2-2 (wt%) Purified water To. 100 To. 100 Hyaluronic acid liquid 5.0 5.0 β-glucan solution 3.0 3.0 DL-panthenol 0.3 0.3 Allantoin 0.1 0.1 IDT-2Na 0.02 0.02 Betaine 3.0 3.0 glycerin 5.0 5.0 Dipropylene glycol 4.0 4.0 ethanol 3.0 3.0 Fiji-60 Hydrogenated Castor Oil 0.6 0.6 Carbomer 0.15 0.15 Potassium hydroxide 0.07 0.07 Preservative, incense Quantity Quantity Nano seafire-11 (production example-11) 3.0 - Nano seafire-4 (production example-4) - 6.0 Sum 100 100

Formulation Example 3: Pack

ingredient Formulation Example 3-1 (wt%) Formulation Example 3-2 (Weight%) Purified water To.100 To.100 Fiji-4000 0.8 0.8 Polyvinyl Alcohol 217 10.0 10.0 Polyvinyl Alcohol 205 4.0 4.0 glycerin 2.0 2.0 Cellulose gum 0.4 0.4 DL-panthenol 0.2 0.2 ethanol 8.0 8.0 Octyldodeceth-25 0.5 0.5 Incense, preservative Quantity Quantity Nano seafire-11 (production example-11) 3.0 - Nano seafire-4 (production example-4) - 5.0 Sum 100 100

Formulation Example 4: Shampoo

ingredient Formulation Example 4-1 (wt%) Formulation Example 4-2 (Weight%) Purified water To.100 To.100 Alkyl sulfate (30%) 25.0 25.0 Alkyl ether sulfate (30%) 20.0 20.0 Alkyl amidobetaine (30%) 5.0 5.0 Propylene glycol 3.0 3.0 Lauramiddiei 4.0 4.0 IDT-2Na 0.1 0.1 Polyquaternium-10 0.05 0.05 NaCl Quantity Quantity Citric acid Quantity Quantity Preservative, coloring, fragrance Quantity Quantity Nano seafire-11 (production example-11) 3.0 - Nano seafire-4 (production example-4) - 5.0 Sum 100 100

Formulation Example 5: Body Cleanser

ingredient Formulation Example 5-1 (wt%) Formulation Example 5-2 (wt%) Purified water To.100 To.100 Alkyl ether saccharide (30%) 30.0 30.0 Alkyl ether sulfosuccinate (30%) 20.0 20.0 Alkyl amidobetaine (30%) 5.0 5.0 Propylene glycol 5.0 5.0 Betaine 5.0 5.0 Lauramiddiei 4.0 4.0 Cellulose gum 0.05 0.05 Hydrolyzed protein 0.1 0.1 NaCl Quantity Quantity Citric acid Quantity Quantity Preservative, coloring, fragrance Quantity Quantity Nano seafire-11 (production example-11) 2.5 - Nano seafire-4 (production example-4) - 4.0 Sum 100 100

Formulation Example 6: Hair Set Lotion

ingredient Formulation Example 6-1 (wt%) Formulation Example 6-2 (% by weight) Purified water To.100 To.100 Polyvinylpyrrolidone vinyl acetate copolymer 5.0 5.0 ethanol 25.0 25.0 DL-panthenol 0.2 0.2 Castor-10 Methylglucoether 2.0 2.0 Dimethicone Copolyol 1.5 1.5 Hydrolyzed protein 0.2 0.2 Polyquaternium-11 1.0 1.0 incense Quantity Quantity Preservative, pigment Quantity Quantity Nano seafire-11 (production example-11) 2.5 - Nano seafire-4 (production example-4) - 4.0 Sum 100 100

As described in detail above, the present invention provides a nano-vesicle opacifier and a cosmetic composition comprising the same. The cosmetic composition comprising the opacifying agent of the present invention is not only excellent in feeling and stability, but also has a moisturizing effect and very little irritation to the skin.

Claims (11)

The oil component includes 5.0-50.0% by weight, polyol 20.0-80.0% by weight, surfactant 0.1-10.0%, phospholipid 0.5-20.0% by weight, fatty acid 0.05-3.0% by weight and purified water 2.0-30.0% by weight. In the case of an anionic surfactant containing a higher fatty acid, the nanovesicle opaque agent, characterized in that the fatty acid is not used. The oil-based component of claim 1, wherein the oily component is hydrocarbon oil, ester oil, silicone oil, animal or vegetable oil, ethoxylated alkyl ether oil, propoxylated alkyl ether oil, sphingoid lipid , Nanovesicle opaque agent, characterized in that it is selected from the group consisting of ceramide, cerebromide, cholesterol, cytosterol, cholesteryl sulfate, cytosteryl sulfate, C _10-40 fatty alcohol and C _10-40 fatty acid. The method of claim 1, wherein the polyol is selected from the group consisting of propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin, methylpropanediol, isoprene glycol, pentylene glycol, erythritol, xyitol and sorbitol Nanovesicle opacifier to be used. The method of claim 1, wherein the surfactant is an anionic surfactant or alkoxylated alkyl ether, alkoxylated alkyl ester selected from the group consisting of alkylacyl glutamate, alkyl phosphate, alkyl lactylate, dialkyl phosphate and trialkyl phosphate, A nanovesicle opacifying agent, characterized in that it is a nonionic surfactant selected from the group consisting of alkylpolyglycosides, polyglyceryl esters and sugar esters. The nanovesicle opacifier of claim 1 wherein the phospholipid is lecithin. The _nanovesicle opacifier of claim 1 wherein the fatty acid is a saturated or unsaturated fatty acid of a C _12-22 alkyl chain. The nanovesicle opacifier of claim 1, wherein the nanovesicle is manufactured using a high pressure homogenizer. The nanovesicle opacifying agent according to claim 1, wherein the particle size of the nanovesicle is 30-70 nm in diameter. A cosmetic composition comprising the nanovesicle opacifier of any one of claims 1 to 8. 10. The composition of claim 9 wherein the cosmetic composition consists of a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation and spray Cosmetic composition, characterized in that it has a formulation selected from the group. The cosmetic composition according to claim 9, wherein the content of the nanovesicle opacifying agent is 0.1-30.0 wt% based on the total weight of the cosmetic composition.