KR20060035637A - 술폰아미드 치환된 이미다조퀴놀린 - Google Patents
술폰아미드 치환된 이미다조퀴놀린 Download PDFInfo
- Publication number
- KR20060035637A KR20060035637A KR1020057024904A KR20057024904A KR20060035637A KR 20060035637 A KR20060035637 A KR 20060035637A KR 1020057024904 A KR1020057024904 A KR 1020057024904A KR 20057024904 A KR20057024904 A KR 20057024904A KR 20060035637 A KR20060035637 A KR 20060035637A
- Authority
- KR
- South Korea
- Prior art keywords
- imidazo
- quinolin
- amino
- butyl
- mmol
- Prior art date
Links
- 0 C[n]1c2c(cccc3)c3nc(N)c2nc1* Chemical compound C[n]1c2c(cccc3)c3nc(N)c2nc1* 0.000 description 6
- FDURDVQGNXYXGG-UHFFFAOYSA-N CCOCc1nc2c(N)nc(CCCC3)c3c2[n]1CCCNS(C)(=O)=O Chemical compound CCOCc1nc2c(N)nc(CCCC3)c3c2[n]1CCCNS(C)(=O)=O FDURDVQGNXYXGG-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48320003P | 2003-06-27 | 2003-06-27 | |
| US60/483,200 | 2003-06-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20060035637A true KR20060035637A (ko) | 2006-04-26 |
Family
ID=33563911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020057024904A KR20060035637A (ko) | 2003-06-27 | 2004-06-25 | 술폰아미드 치환된 이미다조퀴놀린 |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1638566A4 (zh) |
| JP (1) | JP2007521280A (zh) |
| KR (1) | KR20060035637A (zh) |
| CN (1) | CN1812789B (zh) |
| AR (2) | AR044922A1 (zh) |
| AU (1) | AU2004253929A1 (zh) |
| BR (1) | BRPI0411916A (zh) |
| CA (1) | CA2529322A1 (zh) |
| IL (1) | IL172427A0 (zh) |
| MX (1) | MXPA06000144A (zh) |
| MY (1) | MY157827A (zh) |
| NZ (1) | NZ544330A (zh) |
| RU (1) | RU2374246C2 (zh) |
| TW (2) | TW200514784A (zh) |
| WO (2) | WO2005003065A2 (zh) |
| ZA (1) | ZA200600769B (zh) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040265351A1 (en) | 2003-04-10 | 2004-12-30 | Miller Richard L. | Methods and compositions for enhancing immune response |
| CA2535117A1 (en) | 2003-08-12 | 2005-03-03 | 3M Innovative Properties Company | Oxime substituted imidazo-containing compounds |
| US7897597B2 (en) | 2003-08-27 | 2011-03-01 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted imidazoquinolines |
| EP1660026A4 (en) | 2003-09-05 | 2008-07-16 | 3M Innovative Properties Co | TREATMENT FOR CD5 + B CELL LYMPHOMA |
| WO2005032484A2 (en) | 2003-10-03 | 2005-04-14 | 3M Innovative Properties Company | Alkoxy substituted imidazoquinolines |
| JP2007508305A (ja) | 2003-10-03 | 2007-04-05 | スリーエム イノベイティブ プロパティズ カンパニー | ピラゾロピリジンおよびその類似物 |
| US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
| AU2004291122A1 (en) | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Hydroxylamine substituted imidazo ring compounds |
| CA2545774A1 (en) | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Oxime substituted imidazo ring compounds |
| CA2547020C (en) | 2003-11-25 | 2014-03-25 | 3M Innovative Properties Company | 1h-imidazo[4,5-c]pyridine-4-amine derivatives as immune response modifier |
| EP1689361A4 (en) * | 2003-12-02 | 2009-06-17 | 3M Innovative Properties Co | THERAPEUTIC COMBINATIONS AND PROCESSES WITH IRM COMPOUNDS |
| EP1701955A1 (en) | 2003-12-29 | 2006-09-20 | 3M Innovative Properties Company | Arylalkenyl and arylalkynyl substituted imidazoquinolines |
| WO2005066169A2 (en) | 2003-12-30 | 2005-07-21 | 3M Innovative Properties Company | Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides |
| US8697873B2 (en) | 2004-03-24 | 2014-04-15 | 3M Innovative Properties Company | Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines |
| WO2005123080A2 (en) | 2004-06-15 | 2005-12-29 | 3M Innovative Properties Company | Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines |
| US7915281B2 (en) | 2004-06-18 | 2011-03-29 | 3M Innovative Properties Company | Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method |
| US8541438B2 (en) | 2004-06-18 | 2013-09-24 | 3M Innovative Properties Company | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines |
| US8026366B2 (en) | 2004-06-18 | 2011-09-27 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines |
| US7897609B2 (en) | 2004-06-18 | 2011-03-01 | 3M Innovative Properties Company | Aryl substituted imidazonaphthyridines |
| WO2006083440A2 (en) | 2004-12-30 | 2006-08-10 | 3M Innovative Properties Company | Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds |
| ZA200706251B (en) * | 2004-12-30 | 2008-11-26 | Coley Pharm Group Inc | Immune response modifier formulations and methods |
| AU2005322898B2 (en) | 2004-12-30 | 2011-11-24 | 3M Innovative Properties Company | Chiral fused (1,2)imidazo(4,5-c) ring compounds |
| EP1844201B1 (en) | 2005-02-04 | 2016-08-24 | 3M Innovative Properties Company | Aqueous gel formulations containing immune response modifiers |
| WO2006086449A2 (en) | 2005-02-09 | 2006-08-17 | Coley Pharmaceutical Group, Inc. | Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines |
| EP1846405A2 (en) | 2005-02-11 | 2007-10-24 | 3M Innovative Properties Company | Oxime and hydroxylamine substituted imidazo 4,5-c ring compounds and methods |
| JP2008538550A (ja) | 2005-04-01 | 2008-10-30 | コーリー ファーマシューティカル グループ，インコーポレイテッド | ウイルス感染および腫瘍性疾患を処置するためのサイトカイン生合成の調節因子としての１−置換ピラゾロ（３，４−ｃ）環状化合物 |
| JP2008535832A (ja) | 2005-04-01 | 2008-09-04 | コーリー ファーマシューティカル グループ，インコーポレイテッド | ピラゾロピリジン−１，４−ジアミン、およびそのアナログ |
| ZA200803029B (en) * | 2005-09-09 | 2009-02-25 | Coley Pharm Group Inc | Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods |
| AU2006287270A1 (en) * | 2005-09-09 | 2007-03-15 | Coley Pharmaceutical Group, Inc. | Amide and carbamate derivatives of N-{2-[4-amino-2- (ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-1,1-dimethylethyl}methanesulfonamide and methods |
| JP4551962B2 (ja) * | 2005-09-23 | 2010-09-29 | コーリー ファーマシューティカル グループ，インコーポレイテッド | １Ｈ−イミダゾ［４，５−ｃ］ピリジンおよびその類似体のための方法 |
| WO2007100634A2 (en) | 2006-02-22 | 2007-09-07 | 3M Innovative Properties Company | Immune response modifier conjugates |
| WO2008008432A2 (en) | 2006-07-12 | 2008-01-17 | Coley Pharmaceutical Group, Inc. | Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods |
| RS53059B (en) | 2008-03-24 | 2014-04-30 | 4Sc Discovery Gmbh | NEW SUBSTITUTED IMIDAZOCHINOLINES |
| JP2013534248A (ja) | 2010-08-17 | 2013-09-02 | スリーエム イノベイティブ プロパティズ カンパニー | 脂質付加された免疫反応調節化合物の組成物、製剤及び方法 |
| CN103582496B (zh) | 2011-06-03 | 2016-05-11 | 3M创新有限公司 | 具有聚乙二醇链段的异双官能连接基以及由其制成的免疫应答调节剂缀合物 |
| WO2012167081A1 (en) | 2011-06-03 | 2012-12-06 | 3M Innovative Properties Company | Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom |
| WO2015092592A1 (en) | 2013-12-17 | 2015-06-25 | Pfizer Inc. | Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors |
| KR102161364B1 (ko) * | 2015-09-14 | 2020-09-29 | 화이자 인코포레이티드 | LRRK2 억제제로서 이미다조[4,5-c]퀴놀린 및 이미다조[4,5-c][1,5]나프티리딘 유도체 |
| BR112019000071A2 (pt) | 2016-07-07 | 2019-07-02 | Bolt Biotherapeutics Inc | conjugados adjuvantes de anticorpo |
| MX2019010756A (es) | 2017-03-10 | 2020-01-20 | Pfizer | Derivados novedosos de imidazo[4,5-c]quinolina como inhibidores de cinasa 2 rica en repetición de leucina (lrrk2). |
| PT3679025T (pt) | 2017-09-06 | 2022-06-01 | BioNTech SE | Imidazoquinolinas substituídas como agonistas de tlr7 |
| EP3728255B1 (en) | 2017-12-20 | 2022-01-26 | 3M Innovative Properties Company | Amide substituted imidazo[4,5-c]quinoline compounds with a branched chain linking group for use as an immune response modifier |
| AU2020241686A1 (en) | 2019-03-15 | 2021-11-04 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting HER2 |
| JP2023507322A (ja) * | 2019-12-20 | 2023-02-22 | ナミ セラピューティクス， インコーポレイテッド | がんの処置において有用なＴｏｌｌ様受容体（「ＴＬＲ」）アゴニストプロドラッグを含有する製剤化および／または共製剤化リポソーム組成物ならびにその方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6331539B1 (en) * | 1999-06-10 | 2001-12-18 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
| AU2002343728A1 (en) * | 2001-11-16 | 2003-06-10 | 3M Innovative Properties Company | Methods and compositions related to irm compounds and toll-like receptor pathways |
| US6677349B1 (en) * | 2001-12-21 | 2004-01-13 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
-
2004
- 2004-06-24 MY MYPI20042461A patent/MY157827A/en unknown
- 2004-06-25 AR ARP040102247A patent/AR044922A1/es unknown
- 2004-06-25 CA CA002529322A patent/CA2529322A1/en not_active Abandoned
- 2004-06-25 CN CN2004800181459A patent/CN1812789B/zh not_active Expired - Fee Related
- 2004-06-25 TW TW093118635A patent/TW200514784A/zh unknown
- 2004-06-25 EP EP04756208A patent/EP1638566A4/en not_active Withdrawn
- 2004-06-25 AR ARP040102248A patent/AR044923A1/es unknown
- 2004-06-25 AU AU2004253929A patent/AU2004253929A1/en not_active Abandoned
- 2004-06-25 BR BRPI0411916-9A patent/BRPI0411916A/pt not_active IP Right Cessation
- 2004-06-25 JP JP2006517711A patent/JP2007521280A/ja active Pending
- 2004-06-25 KR KR1020057024904A patent/KR20060035637A/ko not_active Application Discontinuation
- 2004-06-25 WO PCT/US2004/020607 patent/WO2005003065A2/en active Application Filing
- 2004-06-25 TW TW093118636A patent/TW200511992A/zh unknown
- 2004-06-25 NZ NZ544330A patent/NZ544330A/en unknown
- 2004-06-25 RU RU2005138915/04A patent/RU2374246C2/ru not_active IP Right Cessation
- 2004-06-25 WO PCT/US2004/020606 patent/WO2005003064A2/en not_active Application Discontinuation
- 2004-06-25 MX MXPA06000144A patent/MXPA06000144A/es unknown
-
2005
- 2005-12-07 IL IL172427A patent/IL172427A0/en unknown
-
2006
- 2006-01-26 ZA ZA200600769A patent/ZA200600769B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2529322A1 (en) | 2005-01-13 |
| NZ544330A (en) | 2009-06-26 |
| EP1638566A2 (en) | 2006-03-29 |
| TW200511992A (en) | 2005-04-01 |
| MY157827A (en) | 2016-07-29 |
| WO2005003064A3 (en) | 2005-03-31 |
| ZA200600769B (en) | 2007-05-30 |
| AR044922A1 (es) | 2005-10-12 |
| WO2005003064A2 (en) | 2005-01-13 |
| TW200514784A (en) | 2005-05-01 |
| AR044923A1 (es) | 2005-10-12 |
| EP1638566A4 (en) | 2009-03-25 |
| CN1812789B (zh) | 2010-07-14 |
| MXPA06000144A (es) | 2006-04-07 |
| BRPI0411916A (pt) | 2006-08-15 |
| JP2007521280A (ja) | 2007-08-02 |
| AU2004253929A1 (en) | 2005-01-13 |
| RU2005138915A (ru) | 2006-06-27 |
| WO2005003065A3 (en) | 2005-03-10 |
| CN1812789A (zh) | 2006-08-02 |
| IL172427A0 (en) | 2006-04-10 |
| RU2374246C2 (ru) | 2009-11-27 |
| WO2005003065A2 (en) | 2005-01-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| E601 | Decision to refuse application |