WO2005003064A3 - Sulfonamide substituted imidazoquinolines - Google Patents
Sulfonamide substituted imidazoquinolines Download PDFInfo
- Publication number
- WO2005003064A3 WO2005003064A3 PCT/US2004/020606 US2004020606W WO2005003064A3 WO 2005003064 A3 WO2005003064 A3 WO 2005003064A3 US 2004020606 W US2004020606 W US 2004020606W WO 2005003064 A3 WO2005003064 A3 WO 2005003064A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sulfonamide substituted
- useful
- substituted imidazoquinolines
- compounds
- imidazoquinolines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48320003P | 2003-06-27 | 2003-06-27 | |
US60/483,200 | 2003-06-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005003064A2 WO2005003064A2 (en) | 2005-01-13 |
WO2005003064A3 true WO2005003064A3 (en) | 2005-03-31 |
Family
ID=33563911
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/020607 WO2005003065A2 (en) | 2003-06-27 | 2004-06-25 | Sulfonamide substituted imidazoquinolines |
PCT/US2004/020606 WO2005003064A2 (en) | 2003-06-27 | 2004-06-25 | Sulfonamide substituted imidazoquinolines |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/020607 WO2005003065A2 (en) | 2003-06-27 | 2004-06-25 | Sulfonamide substituted imidazoquinolines |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1638566A4 (en) |
JP (1) | JP2007521280A (en) |
KR (1) | KR20060035637A (en) |
CN (1) | CN1812789B (en) |
AR (2) | AR044922A1 (en) |
AU (1) | AU2004253929A1 (en) |
BR (1) | BRPI0411916A (en) |
CA (1) | CA2529322A1 (en) |
IL (1) | IL172427A0 (en) |
MX (1) | MXPA06000144A (en) |
MY (1) | MY157827A (en) |
NZ (1) | NZ544330A (en) |
RU (1) | RU2374246C2 (en) |
TW (2) | TW200514784A (en) |
WO (2) | WO2005003065A2 (en) |
ZA (1) | ZA200600769B (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9006264B2 (en) | 2004-06-18 | 2015-04-14 | 3M Innovative Properties Company | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines |
US9107958B2 (en) | 2011-06-03 | 2015-08-18 | 3M Innovative Properties Company | Hydrazino 1H-imidazoquinolin-4-amines and conjugates made therefrom |
US9145410B2 (en) | 2003-10-03 | 2015-09-29 | 3M Innovative Properties Company | Pyrazolopyridines and analogs thereof |
US9242980B2 (en) | 2010-08-17 | 2016-01-26 | 3M Innovative Properties Company | Lipidated immune response modifier compound compositions, formulations, and methods |
US9328110B2 (en) | 2003-11-25 | 2016-05-03 | 3M Innovative Properties Company | Substituted imidazo ring systems and methods |
US9365567B2 (en) | 2003-10-03 | 2016-06-14 | 3M Innovative Properties Company | Alkoxy substituted imidazoquinolines |
US9475804B2 (en) | 2011-06-03 | 2016-10-25 | 3M Innovative Properties Company | Heterobifunctional linkers with polyethylene glycol segments and immune response modifier conjugates made therefrom |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040265351A1 (en) | 2003-04-10 | 2004-12-30 | Miller Richard L. | Methods and compositions for enhancing immune response |
AR045260A1 (en) | 2003-08-12 | 2005-10-19 | 3M Innovative Properties Co | COMPOUNDS CONTAINING IMIDAZO-OXIMA REPLACED |
AR045529A1 (en) | 2003-08-27 | 2005-11-02 | 3M Innovative Properties Co | IMIDAZOQUINOLINAS REPLACED WITH ARILOXI OR ARILALQUILENOXI GROUPS |
US20050054665A1 (en) | 2003-09-05 | 2005-03-10 | 3M Innovative Properties Company | Treatment for CD5+ B cell lymphoma |
US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
US8598192B2 (en) | 2003-11-14 | 2013-12-03 | 3M Innovative Properties Company | Hydroxylamine substituted imidazoquinolines |
EP1685129A4 (en) | 2003-11-14 | 2008-10-22 | 3M Innovative Properties Co | Oxime substituted imidazo ring compounds |
US8940755B2 (en) * | 2003-12-02 | 2015-01-27 | 3M Innovative Properties Company | Therapeutic combinations and methods including IRM compounds |
JP2007517035A (en) | 2003-12-29 | 2007-06-28 | スリーエム イノベイティブ プロパティズ カンパニー | Arylalkenyl and arylalkynyl substituted imidazoquinolines |
US8735421B2 (en) | 2003-12-30 | 2014-05-27 | 3M Innovative Properties Company | Imidazoquinolinyl sulfonamides |
EP1730143A2 (en) | 2004-03-24 | 2006-12-13 | 3M Innovative Properties Company | Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines |
WO2005123080A2 (en) | 2004-06-15 | 2005-12-29 | 3M Innovative Properties Company | Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines |
WO2006038923A2 (en) | 2004-06-18 | 2006-04-13 | 3M Innovative Properties Company | Aryl substituted imidazonaphthyridines |
WO2006065280A2 (en) | 2004-06-18 | 2006-06-22 | 3M Innovative Properties Company | Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods |
WO2006009826A1 (en) | 2004-06-18 | 2006-01-26 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines |
EP1831226B1 (en) | 2004-12-30 | 2012-08-08 | 3M Innovative Properties Company | Chiral tetracyclic compounds inducing interferon biosynthesis |
AU2005322843B2 (en) * | 2004-12-30 | 2012-03-08 | 3M Innovative Properties Company | Immune response modifier formulations and methods |
US8034938B2 (en) | 2004-12-30 | 2011-10-11 | 3M Innovative Properties Company | Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds |
WO2006084251A2 (en) | 2005-02-04 | 2006-08-10 | Coley Pharmaceutical Group, Inc. | Aqueous gel formulations containing immune reponse modifiers |
ES2475728T3 (en) | 2005-02-09 | 2014-07-11 | 3M Innovative Properties Company | Thiazoloquinolines and alkoxy substituted thiazolonaphthyridines |
WO2006086634A2 (en) | 2005-02-11 | 2006-08-17 | Coley Pharmaceutical Group, Inc. | Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods |
CA2602683A1 (en) | 2005-04-01 | 2006-10-12 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridine-1,4-diamines and analogs thereof |
AU2006232375A1 (en) | 2005-04-01 | 2006-10-12 | Coley Pharmaceutical Group, Inc. | 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases |
JP2009507856A (en) * | 2005-09-09 | 2009-02-26 | コーリー ファーマシューティカル グループ,インコーポレイテッド | Amide and carbamate derivatives of N- {2- [4-amino-2- (ethoxymethyl) -1H-imidazo [4,5-c] quinolin-1-yl] -1,1-dimethylethyl} methanesulfonamide and Method |
ZA200803029B (en) | 2005-09-09 | 2009-02-25 | Coley Pharm Group Inc | Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods |
WO2007035935A1 (en) * | 2005-09-23 | 2007-03-29 | Coley Pharmaceutical Group, Inc. | METHOD FOR 1H-IMIDAZO[4,5-c]PYRIDINES AND ANALOGS THEREOF |
US8951528B2 (en) | 2006-02-22 | 2015-02-10 | 3M Innovative Properties Company | Immune response modifier conjugates |
US7906506B2 (en) | 2006-07-12 | 2011-03-15 | 3M Innovative Properties Company | Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods |
SI2276486T1 (en) * | 2008-03-24 | 2014-01-31 | 4Sc Discovery Gmbh | Novel substituted imidazoquinolines |
JP6487921B2 (en) | 2013-12-17 | 2019-03-20 | ファイザー・インク | Novel 3,4-disubstituted-1H-pyrrolo [2,3-b] pyridines and 4,5-disubstituted-7H-pyrrolo [2,3-c] pyridazines as LRRK2 inhibitors |
RU2722149C1 (en) | 2015-09-14 | 2020-05-27 | Пфайзер Инк. | New derivatives of imidazo [4,5-c] quinolines and imidazo [4,5-c] [1,5] naphthyridines as lrrk2 inhibitors |
AU2017292934B2 (en) | 2016-07-07 | 2024-04-04 | Bolt Biotherapeutics, Inc. | Antibody adjuvant conjugates |
KR102582626B1 (en) | 2017-03-10 | 2023-09-22 | 화이자 인코포레이티드 | Novel imidazo[4,5-C]quinoline derivatives as LRRK2 inhibitors |
CN111132969B (en) | 2017-09-06 | 2024-01-30 | 生物技术公司 | Substituted imidazoquinolines as TLR7 agonists |
EP3728255B1 (en) | 2017-12-20 | 2022-01-26 | 3M Innovative Properties Company | Amide substituted imidazo[4,5-c]quinoline compounds with a branched chain linking group for use as an immune response modifier |
WO2020190725A1 (en) | 2019-03-15 | 2020-09-24 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting her2 |
CA3161668A1 (en) * | 2019-12-20 | 2021-06-24 | Nammi Therapeutics, Inc. | Formulated and/or co-formulated liposome compositions containing toll-like receptor ("tlr") agonist prodrugs useful in the treatment of cancer and methods thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003043572A2 (en) * | 2001-11-16 | 2003-05-30 | 3M Innovative Properties Company | Methods and compositions related to irm compounds and toll-like receptor pathways |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6331539B1 (en) * | 1999-06-10 | 2001-12-18 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
US6677349B1 (en) * | 2001-12-21 | 2004-01-13 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
-
2004
- 2004-06-24 MY MYPI20042461A patent/MY157827A/en unknown
- 2004-06-25 NZ NZ544330A patent/NZ544330A/en unknown
- 2004-06-25 CA CA002529322A patent/CA2529322A1/en not_active Abandoned
- 2004-06-25 TW TW093118635A patent/TW200514784A/en unknown
- 2004-06-25 AU AU2004253929A patent/AU2004253929A1/en not_active Abandoned
- 2004-06-25 CN CN2004800181459A patent/CN1812789B/en not_active Expired - Fee Related
- 2004-06-25 MX MXPA06000144A patent/MXPA06000144A/en unknown
- 2004-06-25 JP JP2006517711A patent/JP2007521280A/en active Pending
- 2004-06-25 TW TW093118636A patent/TW200511992A/en unknown
- 2004-06-25 EP EP04756208A patent/EP1638566A4/en not_active Withdrawn
- 2004-06-25 AR ARP040102247A patent/AR044922A1/en unknown
- 2004-06-25 AR ARP040102248A patent/AR044923A1/en unknown
- 2004-06-25 KR KR1020057024904A patent/KR20060035637A/en not_active Application Discontinuation
- 2004-06-25 WO PCT/US2004/020607 patent/WO2005003065A2/en active Application Filing
- 2004-06-25 BR BRPI0411916-9A patent/BRPI0411916A/en not_active IP Right Cessation
- 2004-06-25 WO PCT/US2004/020606 patent/WO2005003064A2/en not_active Application Discontinuation
- 2004-06-25 RU RU2005138915/04A patent/RU2374246C2/en not_active IP Right Cessation
-
2005
- 2005-12-07 IL IL172427A patent/IL172427A0/en unknown
-
2006
- 2006-01-26 ZA ZA200600769A patent/ZA200600769B/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003043572A2 (en) * | 2001-11-16 | 2003-05-30 | 3M Innovative Properties Company | Methods and compositions related to irm compounds and toll-like receptor pathways |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9145410B2 (en) | 2003-10-03 | 2015-09-29 | 3M Innovative Properties Company | Pyrazolopyridines and analogs thereof |
US9365567B2 (en) | 2003-10-03 | 2016-06-14 | 3M Innovative Properties Company | Alkoxy substituted imidazoquinolines |
US9328110B2 (en) | 2003-11-25 | 2016-05-03 | 3M Innovative Properties Company | Substituted imidazo ring systems and methods |
US9006264B2 (en) | 2004-06-18 | 2015-04-14 | 3M Innovative Properties Company | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines |
US9550773B2 (en) | 2004-06-18 | 2017-01-24 | 3M Innovative Properties Company | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines |
US9242980B2 (en) | 2010-08-17 | 2016-01-26 | 3M Innovative Properties Company | Lipidated immune response modifier compound compositions, formulations, and methods |
US9107958B2 (en) | 2011-06-03 | 2015-08-18 | 3M Innovative Properties Company | Hydrazino 1H-imidazoquinolin-4-amines and conjugates made therefrom |
US9475804B2 (en) | 2011-06-03 | 2016-10-25 | 3M Innovative Properties Company | Heterobifunctional linkers with polyethylene glycol segments and immune response modifier conjugates made therefrom |
US9585968B2 (en) | 2011-06-03 | 2017-03-07 | 3M Innovative Properties Company | Hydrazino 1H-imidazoquinolin-4-amines and conjugates made therefrom |
Also Published As
Publication number | Publication date |
---|---|
WO2005003065A2 (en) | 2005-01-13 |
WO2005003065A3 (en) | 2005-03-10 |
ZA200600769B (en) | 2007-05-30 |
NZ544330A (en) | 2009-06-26 |
IL172427A0 (en) | 2006-04-10 |
JP2007521280A (en) | 2007-08-02 |
CA2529322A1 (en) | 2005-01-13 |
CN1812789B (en) | 2010-07-14 |
AR044922A1 (en) | 2005-10-12 |
RU2005138915A (en) | 2006-06-27 |
WO2005003064A2 (en) | 2005-01-13 |
CN1812789A (en) | 2006-08-02 |
KR20060035637A (en) | 2006-04-26 |
RU2374246C2 (en) | 2009-11-27 |
AR044923A1 (en) | 2005-10-12 |
EP1638566A4 (en) | 2009-03-25 |
MY157827A (en) | 2016-07-29 |
TW200511992A (en) | 2005-04-01 |
MXPA06000144A (en) | 2006-04-07 |
BRPI0411916A (en) | 2006-08-15 |
AU2004253929A1 (en) | 2005-01-13 |
EP1638566A2 (en) | 2006-03-29 |
TW200514784A (en) | 2005-05-01 |
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