KR20020060265A - 코 통로로의 약제 투여를 위한 시스템 및 방법 - Google Patents
코 통로로의 약제 투여를 위한 시스템 및 방법 Download PDFInfo
- Publication number
- KR20020060265A KR20020060265A KR1020027007674A KR20027007674A KR20020060265A KR 20020060265 A KR20020060265 A KR 20020060265A KR 1020027007674 A KR1020027007674 A KR 1020027007674A KR 20027007674 A KR20027007674 A KR 20027007674A KR 20020060265 A KR20020060265 A KR 20020060265A
- Authority
- KR
- South Korea
- Prior art keywords
- vial
- pump
- mechanical plug
- nozzle
- medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/460,050 | 1999-12-14 | ||
| US09/460,050 US6302101B1 (en) | 1999-12-14 | 1999-12-14 | System and method for application of medicament into the nasal passage |
| PCT/US2000/033535 WO2001043794A2 (en) | 1999-12-14 | 2000-12-11 | System and method for application of medicament into the nasal passage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20020060265A true KR20020060265A (ko) | 2002-07-16 |
Family
ID=23827225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020027007674A Withdrawn KR20020060265A (ko) | 1999-12-14 | 2000-12-11 | 코 통로로의 약제 투여를 위한 시스템 및 방법 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6302101B1 (enExample) |
| EP (3) | EP2263725A1 (enExample) |
| JP (2) | JP4680463B2 (enExample) |
| KR (1) | KR20020060265A (enExample) |
| AU (1) | AU2084401A (enExample) |
| CA (1) | CA2394559C (enExample) |
| DE (1) | DE60042560D1 (enExample) |
| ES (1) | ES2328219T3 (enExample) |
| WO (1) | WO2001043794A2 (enExample) |
Families Citing this family (141)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6465743B1 (en) * | 1994-12-05 | 2002-10-15 | Motorola, Inc. | Multi-strand substrate for ball-grid array assemblies and method |
| US6745763B2 (en) * | 1998-10-27 | 2004-06-08 | Garth T. Webb | Vaporizing device for administering sterile medication |
| DK1140261T3 (da) * | 1999-01-08 | 2003-09-29 | Theodor Schoettli | Injektionssprøjte |
| US6644305B2 (en) | 2000-04-14 | 2003-11-11 | Trudell Medical International | Nasal inhaler |
| US7331944B2 (en) | 2000-10-23 | 2008-02-19 | Medical Instill Technologies, Inc. | Ophthalmic dispenser and associated method |
| CN1328149C (zh) * | 2000-10-23 | 2007-07-25 | 因斯蒂尔医学技术有限公司 | 具有外壳和柔性内部气囊的流体分配器 |
| FR2817245B1 (fr) * | 2000-11-30 | 2003-05-02 | Valois Sa | Dispositif de distribution de produit fluide |
| US6644309B2 (en) * | 2001-01-12 | 2003-11-11 | Becton, Dickinson And Company | Medicament respiratory delivery device and method |
| US7168746B2 (en) * | 2001-05-02 | 2007-01-30 | Medical Instill Technologies, Inc. | Apparatus for applying and removing contact lenses and related method |
| US6745760B2 (en) | 2001-05-15 | 2004-06-08 | Trudell Medical International | Medicament applicator |
| US20030041860A1 (en) * | 2001-08-29 | 2003-03-06 | Verona Steven N. | Particulate dispenser |
| EP1450885B1 (en) * | 2001-09-28 | 2015-04-22 | Kurve Technology, Inc. | Nasal nebulizer |
| GB2380410B (en) * | 2001-10-05 | 2003-11-19 | Alchemy Healthcare Ltd | Apparatus for the nasal or oral delivery of a medicament |
| EP1446328B1 (en) * | 2001-10-16 | 2017-05-31 | Medical Instill Technologies, Inc. | DISPENSER WITH SEALED CHAMBER AND ONE−WAY VALVE FOR PROVIDING METERED AMOUNTS OF SUBSTANCES |
| US7021561B2 (en) * | 2001-12-18 | 2006-04-04 | Becton, Dickinson And Company | Spray device and method |
| GB0204829D0 (en) | 2002-03-01 | 2002-04-17 | Glaxo Group Ltd | A fluid dispensing device |
| GB0207817D0 (en) * | 2002-04-04 | 2002-05-15 | Optinose As | Nasal devices |
| US20050199654A1 (en) * | 2002-04-10 | 2005-09-15 | Disop Nordic Holding Aps | Tube with self-closing mechanism for liquid container |
| USD501498S1 (en) | 2002-05-02 | 2005-02-01 | Medical Instill Technologies, Inc. | Automatic contact lens applicator |
| US8122881B2 (en) * | 2002-05-09 | 2012-02-28 | Kurve Technology, Inc. | Particle dispersion device for nasal delivery |
| CN100528257C (zh) * | 2002-05-09 | 2009-08-19 | 葛兰素集团有限公司 | 流体分配设备 |
| GB0215270D0 (en) | 2002-07-02 | 2002-08-14 | Optinose As | Nasal devices |
| DE60239639D1 (de) * | 2002-07-31 | 2011-05-12 | Chiesi Farma Spa | Pulverinhalator |
| WO2004014567A1 (en) * | 2002-08-06 | 2004-02-19 | Glaxo Group Limited | A dispenser |
| AU2003273230A1 (en) | 2002-08-13 | 2004-02-25 | Medical Instill Technologies, Inc. | Container and valve assembly for storing and dispensing substances, and related method |
| CN101274685B (zh) | 2002-08-13 | 2011-09-07 | 因斯蒂尔医学技术有限公司 | 储存装置及存储方法 |
| USD520047S1 (en) | 2002-11-06 | 2006-05-02 | Medical Instill Technologies, Inc. | Automatic contact lens applicator |
| USD529941S1 (en) | 2002-11-06 | 2006-10-10 | Medical Instill Technologies, Inc. | Automatic contact lens applicator |
| CA108491S (en) | 2002-11-06 | 2007-02-13 | Medical Instill Tech Inc | Contact lens applicator |
| USD480475S1 (en) | 2002-12-18 | 2003-10-07 | Glaxo Group Limited | Actuator body for an inhalation device |
| WO2004101027A2 (en) | 2003-05-12 | 2004-11-25 | Medical Instill Technologies, Inc. | Dispenser and apparatus for fillling a dispenser |
| US7226231B2 (en) * | 2003-07-17 | 2007-06-05 | Medical Instill Technologies, Inc. | Piston-type dispenser with one-way valve for storing and dispensing metered amounts of substances |
| ES1055823Y (es) * | 2003-10-27 | 2004-05-01 | Salido Yolanda Chia | Biberon esteril. |
| GB0405477D0 (en) * | 2004-03-11 | 2004-04-21 | Glaxo Group Ltd | A fluid dispensing device |
| CN102028994B (zh) | 2003-11-03 | 2013-04-24 | 葛兰素集团有限公司 | 流体分配装置 |
| US7845517B2 (en) * | 2003-12-10 | 2010-12-07 | Medical Instill Technologies Inc. | Container and one-way valve assembly for storing and dispensing substances, and related method |
| US7264142B2 (en) | 2004-01-27 | 2007-09-04 | Medical Instill Technologies, Inc. | Dispenser having variable-volume storage chamber and depressible one-way valve assembly for dispensing creams and other substances |
| PL1725285T3 (pl) | 2004-03-10 | 2020-03-31 | Glaxo Group Limited | Urządzenie dozujące z członem ograniczającym |
| GB0407627D0 (en) * | 2004-04-02 | 2004-05-05 | Vectura Ltd | Corkscrew pump |
| US7204246B1 (en) * | 2004-07-08 | 2007-04-17 | Joseph Berinato | Air self-contained oxygen inhaler |
| DE102005009294A1 (de) * | 2004-07-13 | 2006-02-16 | Ing. Erich Pfeiffer Gmbh | Spender für Medien |
| US20060045849A1 (en) * | 2004-08-24 | 2006-03-02 | Farhan Taghizadeh | Method of customizing the fragrance of nasal medications |
| JP2008514310A (ja) * | 2004-09-27 | 2008-05-08 | メディカル・インスティル・テクノロジーズ・インコーポレイテッド | 物質の貯蔵および定量分注用の一方向弁を有する横方向作動分注器 |
| US7637400B2 (en) * | 2004-12-10 | 2009-12-29 | Medical Instill Technologies, Inc. | Container and valve assembly for storing and dispensing substances, and related method |
| FR2882349B1 (fr) * | 2005-02-21 | 2007-05-25 | Tebro Sa Luxembourgeoise | Tete de distribution de produit fluide. |
| US7306129B2 (en) * | 2005-11-03 | 2007-12-11 | Stewart Swiss | One way valve assembly |
| US7853321B2 (en) * | 2005-03-14 | 2010-12-14 | Boston Scientific Neuromodulation Corporation | Stimulation of a stimulation site within the neck or head |
| GB0507224D0 (en) * | 2005-04-09 | 2005-05-18 | Glaxo Group Ltd | A fluid dispensing device |
| US20060264855A1 (en) * | 2005-05-20 | 2006-11-23 | Boris Goldenberg | Method, apparatus and cartridge packing for dosage medicine delivery |
| DE102005032705B4 (de) * | 2005-05-24 | 2009-01-08 | Tecpharma Licensing Ag | Kunststofffeder |
| GB0518355D0 (en) * | 2005-09-08 | 2005-10-19 | Glaxo Group Ltd | An inhaler |
| US7775398B2 (en) * | 2005-10-26 | 2010-08-17 | Medical Instill Technologies, Inc. | Container and one-way valve assembly for storing and dispensing substances, and related method |
| EP1984049A1 (en) * | 2006-01-19 | 2008-10-29 | Optinose AS | Nasal administration |
| GB0610666D0 (en) * | 2006-05-30 | 2006-07-05 | Glaxo Group Ltd | Fluid dispenser |
| WO2008061041A2 (en) * | 2006-11-11 | 2008-05-22 | Medical Instill Technologies, Inc. | Multiple dose delivery device with manually depressible actuator and one-way valve for storing and dispensing substances, and related method |
| FR2909288B1 (fr) * | 2006-12-01 | 2009-02-06 | Jose Bensoussan | Embout nasal pour dispositif d'aspiration de secretions nasales et dispositif d'aspiration de secretions nasales comprenant cet embout nasal |
| US20090025328A1 (en) * | 2007-02-01 | 2009-01-29 | Elite Products, Llc | Mechanical plug and method for using the same |
| US8210167B2 (en) * | 2007-03-02 | 2012-07-03 | Corbco, Inc. | Manually operated monodose nasal sprayer |
| US20080210228A1 (en) * | 2007-03-02 | 2008-09-04 | Corbco, Inc. | Monodose nasal sprayer |
| DE102007023012B4 (de) * | 2007-05-15 | 2025-04-30 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Zerstäuber |
| KR101618351B1 (ko) * | 2007-05-30 | 2016-05-04 | 글락소 그룹 리미티드 | 유체 디스펜서 |
| JP5470264B2 (ja) | 2007-11-19 | 2014-04-16 | ケアフュージョン2200、インコーポレイテッド | 呼吸治療のための患者インターフェイスアセンブリ |
| AU2008331300B2 (en) | 2007-11-29 | 2014-01-09 | Glaxo Group Limited | A dispensing device |
| DE102007063213B3 (de) * | 2007-12-20 | 2009-06-18 | Ing. Erich Pfeiffer Gmbh | Austragsvorrichtung zur nasalen Anwendung |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| EP3272379A1 (en) | 2008-02-07 | 2018-01-24 | The University of Washington | Circumferential aerosol device |
| DE102008002773A1 (de) * | 2008-02-18 | 2009-08-20 | Evonik Stockhausen Gmbh | Saugpumpe für eine Spendereinheit und Spendereinheit |
| FR2929249B1 (fr) * | 2008-03-27 | 2012-02-17 | Rexam Pharma La Verpilliere | Dispositif de distribution de liquide contenu dans un reservoir |
| US10011906B2 (en) | 2009-03-31 | 2018-07-03 | Beohringer Ingelheim International Gmbh | Method for coating a surface of a component |
| US9265910B2 (en) | 2009-05-18 | 2016-02-23 | Boehringer Ingelheim International Gmbh | Adapter, inhalation device, and nebulizer |
| CA2760751A1 (en) * | 2009-05-20 | 2010-11-25 | Sanofi-Aventis Deutschland Gmbh | Assembly for use in a drug delivery device |
| FR2948343A1 (fr) * | 2009-07-22 | 2011-01-28 | Rexam Dispensing Smt | Bouton poussoir pour un systeme de distribution d'un produit sous pression |
| US8511517B2 (en) * | 2009-11-05 | 2013-08-20 | Fishman Corporation | Protective syringe sleeve |
| WO2011064163A1 (en) | 2009-11-25 | 2011-06-03 | Boehringer Ingelheim International Gmbh | Nebulizer |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| AP3141A (en) | 2009-11-25 | 2015-02-28 | Boehringer Ingelheim Int | Nebulizer |
| US9943654B2 (en) | 2010-06-24 | 2018-04-17 | Boehringer Ingelheim International Gmbh | Nebulizer |
| CA3111516C (en) | 2011-03-03 | 2023-05-23 | Impel Neuropharma, Inc. | Nasal drug delivery device |
| WO2012130757A1 (de) | 2011-04-01 | 2012-10-04 | Boehringer Ingelheim International Gmbh | Medizinisches gerät mit behälter |
| AU2012253569B2 (en) | 2011-05-09 | 2018-02-15 | Impel Pharmaceuticals Inc. | Nozzles for nasal drug delivery |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| KR101195175B1 (ko) * | 2012-02-03 | 2012-10-29 | 김현하 | 휴대용 마스크 장치 |
| US8800824B2 (en) * | 2012-02-29 | 2014-08-12 | Alfonso M. Gañan-Calvo | Sequential delivery valve apparatus and methods |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| JP6022304B2 (ja) * | 2012-10-31 | 2016-11-09 | 株式会社吉野工業所 | 蓄圧式噴出ノズル及び、それを備える蓄圧式シリンジ型噴出器 |
| KR102483889B1 (ko) | 2012-12-04 | 2023-01-03 | 말린크로트 파마슈티칼스 아일랜드 리미티드 | 일산화질소 전달 동안 투약량의 희석을 최소화하기 위한 캐뉼라 |
| US9795756B2 (en) | 2012-12-04 | 2017-10-24 | Mallinckrodt Hospital Products IP Limited | Cannula for minimizing dilution of dosing during nitric oxide delivery |
| JP6113620B2 (ja) * | 2012-12-27 | 2017-04-12 | 株式会社吉野工業所 | シリンジ型噴出容器 |
| JP5944309B2 (ja) * | 2012-12-27 | 2016-07-05 | 株式会社吉野工業所 | シリンジ型噴出容器 |
| TW201446294A (zh) * | 2013-03-15 | 2014-12-16 | Abbvie Inc | 與局部治療藥物共用之流體塗抹器 |
| KR101457173B1 (ko) * | 2013-03-18 | 2014-11-03 | 양경옥 | 약제 디스펜서 |
| KR101550698B1 (ko) | 2013-03-18 | 2015-09-08 | 에프. 홀저 게엠베하 | 약제 디스펜서 |
| WO2014172455A1 (en) * | 2013-04-16 | 2014-10-23 | Dance Biopharm Inc. | Liquid dispensing and methods for dispensing liquids |
| CA2909954C (en) | 2013-04-28 | 2021-03-23 | Impel Neuropharma, Inc. | Medical unit dose container |
| EP2835146B1 (en) | 2013-08-09 | 2020-09-30 | Boehringer Ingelheim International GmbH | Nebulizer |
| JP6643231B2 (ja) | 2013-08-09 | 2020-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| KR102400202B1 (ko) | 2013-08-20 | 2022-05-23 | 베링거잉겔하임베트메디카게엠베하 | 흡입기 |
| AU2014310918B2 (en) * | 2013-08-20 | 2018-08-16 | Boehringer Ingelheim Vetmedica Gmbh | Inhaler |
| HRP20201987T1 (hr) | 2013-08-20 | 2021-02-05 | Boehringer Ingelheim Vetmedica Gmbh | Inhalator |
| US20220213299A1 (en) * | 2014-03-31 | 2022-07-07 | Boehringer Ingelheim Vetmedica Gmbh | Inhaler |
| EP3139984B1 (en) | 2014-05-07 | 2021-04-28 | Boehringer Ingelheim International GmbH | Nebulizer |
| CN106456913B (zh) | 2014-05-07 | 2019-08-30 | 勃林格殷格翰国际有限公司 | 喷雾器和容器 |
| DK3139979T3 (da) | 2014-05-07 | 2023-10-09 | Boehringer Ingelheim Int | Enhed, forstøver og fremgangsmåde |
| GB201413181D0 (en) * | 2014-07-25 | 2014-09-10 | Dunne Consultancy Services Ltd | Inhaler cartridge system |
| EP3244851B1 (en) | 2015-01-12 | 2024-10-16 | Bausch + Lomb Ireland Limited | Micro-droplet delivery device |
| GB201507687D0 (en) * | 2015-04-30 | 2015-06-17 | Leafgreen Ltd | Pulsed spray nozzle arrangement |
| US20180154092A1 (en) * | 2015-06-12 | 2018-06-07 | Philip Morris Products S.A. | Dispensing mechanism |
| MX2018002895A (es) | 2015-09-10 | 2018-07-06 | Impel Neuropharma Inc | Dispositivo de administracion nasal en linea. |
| WO2017050390A1 (en) * | 2015-09-25 | 2017-03-30 | Sca Hygiene Products Ab | Pump for dispensing fluids |
| CA2999189A1 (en) | 2015-09-25 | 2017-03-30 | Sca Hygiene Products Ab | Pump with a polymer spring |
| KR102412086B1 (ko) | 2017-01-20 | 2022-06-22 | 켄달리온 테라퓨틱스 인코포레이티드 | 압전 유체 분배기 |
| US10368502B2 (en) | 2017-09-25 | 2019-08-06 | Multiple Energy Technologies Llc | Bioceramic and carbon-based hydroponic systems, methods and devices |
| CN111372635B (zh) | 2017-11-21 | 2022-08-16 | 英倍尔制药公司 | 带有入口接口的鼻内装置 |
| EP3713628A4 (en) | 2017-11-21 | 2021-08-18 | Impel Neuropharma Inc. | INTRA-NASAL DEVICE WITH DIVER TUBE |
| CN111712219A (zh) | 2017-12-08 | 2020-09-25 | 科达莱昂治疗公司 | 流体递送对准系统 |
| AU2019205329B2 (en) | 2018-01-05 | 2023-04-20 | Impel Pharmaceuticals Inc. | Intranasal delivery of olanzapine by precision olfactory device |
| RU2020125871A (ru) | 2018-01-05 | 2022-02-07 | Импел Ньюрофарма, Инк. | Интраназальная доставка дигидроэрготамина с помощью прецизионного устройства для доставки в обонятельную область |
| WO2019181575A1 (ja) * | 2018-03-22 | 2019-09-26 | 花王株式会社 | 包装容器および流体吐出器 |
| US20190314198A1 (en) | 2018-04-12 | 2019-10-17 | Kedalion Therapeutics, Inc. | Topical Ocular Delivery Methods and Devices for Use in the Same |
| US12350194B1 (en) | 2018-04-12 | 2025-07-08 | Bausch + Lomb Ireland Limited | Topical ocular delivery of fluids with controlled mass dosing and wireless communication |
| JP2021520266A (ja) | 2018-04-12 | 2021-08-19 | ロケット サイエンス ヘルス コープ. | 鼻腔内薬剤送達デバイス、システム、およびプロセス |
| EP4382149B1 (en) | 2018-05-08 | 2025-11-19 | Akroswiss AG | Bi-dose nasal spray |
| EP3817696B8 (en) | 2018-07-03 | 2024-12-11 | Bausch + Lomb Ireland Limited | Topical ocular delivery devices |
| CN112955134A (zh) | 2018-07-19 | 2021-06-11 | 英倍尔药业股份有限公司 | 用于治疗帕金森氏病的左旋多巴和多巴脱羧酶抑制剂的呼吸道递送 |
| KR102235831B1 (ko) * | 2018-09-07 | 2021-04-05 | 주식회사 하나프로테크 | 약액 디스펜서 |
| CN113473967B (zh) | 2019-01-03 | 2022-09-09 | 英倍尔制药公司 | 经鼻药物递送装置 |
| US12097145B2 (en) | 2019-03-06 | 2024-09-24 | Bausch + Lomb Ireland Limited | Vented multi-dose ocular fluid delivery system |
| US11679028B2 (en) | 2019-03-06 | 2023-06-20 | Novartis Ag | Multi-dose ocular fluid delivery system |
| EP3730219B1 (de) * | 2019-04-26 | 2022-03-23 | Aptar Radolfzell GmbH | Spender zum austrag pharmazeutischer flüssigkeiten |
| WO2020236658A1 (en) | 2019-05-17 | 2020-11-26 | Impel Neuropharma, Inc. | Single-use nasal delivery device |
| WO2021212038A1 (en) * | 2020-04-17 | 2021-10-21 | Kedalion Therapeutics, Inc. | Hydrodynamically actuated preservative free dispensing system having a collapsible liquid reservoir |
| US11938057B2 (en) | 2020-04-17 | 2024-03-26 | Bausch + Lomb Ireland Limited | Hydrodynamically actuated preservative free dispensing system |
| US12290472B2 (en) * | 2020-04-17 | 2025-05-06 | Bausch + Lomb Ireland Limited | Hydrodynamically actuated preservative free dispensing system |
| US11925577B2 (en) * | 2020-04-17 | 2024-03-12 | Bausch + Lomb Ireland Limted | Hydrodynamically actuated preservative free dispensing system |
| US11660407B2 (en) * | 2020-05-14 | 2023-05-30 | Eli Lilly And Company | Nasal delivery device with safety rod |
| US11771591B2 (en) * | 2020-08-17 | 2023-10-03 | Lumio Health Inc. | Liquid medication dispensing apparatus |
| CA3199550A1 (en) * | 2020-12-18 | 2022-06-23 | Stefano Baldessari | Hand dispenser for liquid products |
| KR20240005793A (ko) * | 2021-05-06 | 2024-01-12 | 10엑스베타 | 제어 의료 치료 장치의 사용을 감지하는 시스템 및 방법 |
| USD950712S1 (en) * | 2021-06-11 | 2022-05-03 | ChongQing Moffy Innovation Technology Co., Ltd. | Nasal irrigator |
| FR3124096A1 (fr) | 2021-06-17 | 2022-12-23 | Aptar France Sas | Tête de pulvérisation pour dispositif de distribution de produit fluide |
| EP4568721A1 (en) * | 2023-04-06 | 2025-06-18 | Neutec Inhaler Ilac Sanayi Ve Ticaret Anonim Sirketi | Nebulizer for a fluid contained in a container |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1156915A (en) | 1915-01-22 | 1915-10-19 | Leon Jules Mazoyer | Non-removable bottle-stopper. |
| US1972542A (en) | 1933-02-07 | 1934-09-04 | Henry F Teichmann | Bottle closure |
| US2228936A (en) | 1936-11-25 | 1941-01-14 | Carl W Walter | Flask and closure means therefor |
| US2215392A (en) | 1938-07-04 | 1940-09-17 | Freeman William Simon | Stopper for carboys, bottles, cans, and like containers |
| US2317270A (en) * | 1940-03-02 | 1943-04-20 | Stewart Warner Corp | Fluid dispensing gun |
| US2572383A (en) | 1948-07-26 | 1951-10-23 | Percy L Porter | Closure |
| US3099361A (en) | 1959-11-28 | 1963-07-30 | Ruetz Karl | Container with closing device |
| US3245569A (en) | 1964-08-17 | 1966-04-12 | Essich Helmut | Bottle stopper arrangement |
| DE1263584B (de) | 1966-12-13 | 1968-03-14 | Mauser Kg | Schraubkappe |
| US3733771A (en) | 1971-03-11 | 1973-05-22 | W Megowen | Closure means and method |
| GB1431989A (en) * | 1973-05-31 | 1976-04-14 | Garcia Garcia A L | Hypodermic syringes |
| US4030498A (en) * | 1974-10-25 | 1977-06-21 | Baxter Travenol Laboratories, Inc. | Syringe |
| SE7810107L (sv) | 1977-09-27 | 1979-03-28 | Unilever Nv | Pumputmatningsanordning |
| US4313569A (en) | 1980-05-27 | 1982-02-02 | Ethyl Products Company | Fluid dispenser method and apparatus |
| US4515591A (en) * | 1982-09-28 | 1985-05-07 | Ivac Corporation | Disposable syringe cartridge for fluid delivery apparatus |
| US4771769A (en) * | 1982-12-20 | 1988-09-20 | Schering Corporation | Hand held metered spray dispenser |
| DE3339180C2 (de) | 1983-10-28 | 1993-10-14 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
| US4623337A (en) | 1984-03-08 | 1986-11-18 | Alpha Group, Inc. | Liquid dispensing apparatus |
| NZ212911A (en) * | 1984-07-31 | 1988-06-30 | Glaxo Group Ltd | Aerosol dispensing device; actuator lever acts when cover in open position |
| US4575375A (en) | 1984-11-02 | 1986-03-11 | George Kozam | Periodontal pocket irrigating and medication delivery dispenser and gel system |
| GB8614805D0 (en) * | 1986-06-18 | 1986-07-23 | British American Tobacco Co | Aerosol device |
| US5031610A (en) * | 1987-05-12 | 1991-07-16 | Glaxo Inc. | Inhalation device |
| US5133702A (en) | 1987-11-06 | 1992-07-28 | O.P.T.I.C. | Ocular treatment apparatus |
| US4981479A (en) | 1987-11-06 | 1991-01-01 | Py Daniel C | Ocular treatment apparatus |
| US4946452A (en) | 1987-11-06 | 1990-08-07 | Py Daniel C | Ocular treatment apparatus |
| EP0378935B1 (fr) | 1988-12-20 | 1992-09-23 | Societe Technique De Pulverisation (S.T.E.P.) | Dispositif pour distribuer un liquide ou un lait par goutte de petit volume et ensemble de distribution associée |
| US5085651A (en) | 1989-03-13 | 1992-02-04 | Py Daniel C | Ocular vial |
| DE4041135C2 (de) | 1990-12-21 | 1994-10-20 | Andris Raimund Gmbh & Co Kg | Ansaug- oder Ausgabeventil für eine Dosier- und Spraypumpe zur Abgabe flüssiger, niederviskoser und pastöser Stoffe |
| DE4041136C2 (de) | 1990-12-21 | 1994-06-30 | Andris Raimund Gmbh & Co Kg | Dosier- und Spraypumpe zur Abgabe flüssiger, niederviskoser und pastöser Stoffe |
| CA2062238C (en) | 1991-03-19 | 1996-06-25 | Rudolf Bucheli | Closure for reagent container |
| FR2674747B1 (fr) | 1991-04-05 | 1993-07-30 | Step Soc Tech Pulverisation | Dispositif distributeur de gouttes de petit volume, notamment pour soins ophtalmologiques. |
| GB9114080D0 (en) | 1991-06-28 | 1991-08-14 | Weston Terence E | Atomising valve |
| US5161524A (en) * | 1991-08-02 | 1992-11-10 | Glaxo Inc. | Dosage inhalator with air flow velocity regulating means |
| US5601077A (en) * | 1991-08-07 | 1997-02-11 | Becton, Dickinson And Company | Nasal syringe sprayer with removable dose limiting structure |
| JP3272722B2 (ja) | 1991-12-02 | 2002-04-08 | パイ,ダニエル | 流体滴を小出しするための装置 |
| US5267986A (en) | 1992-04-06 | 1993-12-07 | Self-Instill & Co., Inc. | Cartridge for applying medicament to an eye from a dispenser |
| US5401259A (en) | 1992-04-06 | 1995-03-28 | Py Daniel C | Cartridge for applying medicament to an eye |
| DE4212413C2 (de) | 1992-04-14 | 1996-09-12 | Andris Raimund Gmbh & Co Kg | Dosierpumpe aus Kunststoff für hochviskose, insbesondere pastenartige Medien |
| GB9214819D0 (en) * | 1992-07-13 | 1992-08-26 | Minnesota Mining & Mfg | Valve assemblies |
| US5368582A (en) | 1992-08-10 | 1994-11-29 | The Schepens Eye Research Institute | Method and apparatus for introducing fluid material into an eye |
| US5320845A (en) | 1993-01-06 | 1994-06-14 | Py Daniel C | Apparatus for delivering multiple medicaments to an eye without premixing in the apparatus |
| FR2701399B1 (fr) * | 1993-02-16 | 1995-03-31 | Valois | Dispositif portatif de pulvérisation à actionnement déclenché par l'inhalation. |
| US5411175A (en) | 1993-03-08 | 1995-05-02 | New England Pharmaceuticals, Inc. | Cartridges, devices and methods for dispensing liquids |
| US5819730A (en) * | 1993-06-09 | 1998-10-13 | Glaxo Wellcome Australia Ltd. | Device for administering pharmaceutical substances |
| AU4642393A (en) * | 1993-06-18 | 1995-01-17 | Habley Medical Technology Corporation | Medication sprayer |
| US5358179A (en) | 1993-08-18 | 1994-10-25 | The Procter & Gamble Company | Atomization systems for high viscosity products |
| IT1266794B1 (it) * | 1993-11-09 | 1997-01-21 | Faustino Ballini | Dispositivo a doccia micronizzata per il lavaggio delle cavita' nasali e limitrofe |
| US5462208A (en) | 1994-08-01 | 1995-10-31 | The Procter & Gamble Company | Two-phase dispensing systems utilizing bellows pumps |
| FR2725247B1 (fr) | 1994-10-03 | 1996-12-20 | Py Daniel C | Pompe a fluide sans volume mort |
| FR2729091B1 (fr) | 1995-01-11 | 1997-05-30 | Valois | Buse de pulverisation |
| ES2177771T3 (es) * | 1995-03-14 | 2002-12-16 | Siemens Ag | Dispositivo atomizador ultrasonico con unidad desmontable de dosificacion de precision. |
| DE19518810A1 (de) * | 1995-05-26 | 1996-11-28 | Bayer Ag | Nasal-Applikator |
| US5687882A (en) * | 1995-05-31 | 1997-11-18 | Containaire Incorporated | Flexible dispenser with bladder |
| FR2735357B1 (fr) * | 1995-06-14 | 1997-12-05 | Py Daniel C | Instillateur oculaire double |
| DE19606702A1 (de) * | 1996-02-22 | 1997-08-28 | Caideil M P Teoranta Tourmakea | Austragvorrichtung für Medien |
| JPH09253208A (ja) * | 1996-03-21 | 1997-09-30 | Unisia Jecs Corp | 鼻腔用投薬器 |
| EP0863086A3 (en) * | 1997-02-28 | 1999-04-14 | Daniel Py | System and method for mechanical closure of container openings |
| FR2764005B1 (fr) * | 1997-05-29 | 2004-12-10 | Sofab | Pompe a piston articule |
| US5855322A (en) | 1997-09-10 | 1999-01-05 | Py; Daniel | System and method for one-way spray aerosol tip |
| US6033384A (en) * | 1997-12-18 | 2000-03-07 | Py; Daniel | One-way actuation release mechanism for a system for applying medicament |
-
1999
- 1999-12-14 US US09/460,050 patent/US6302101B1/en not_active Expired - Lifetime
-
2000
- 2000-12-11 EP EP10009781A patent/EP2263725A1/en not_active Withdrawn
- 2000-12-11 WO PCT/US2000/033535 patent/WO2001043794A2/en not_active Ceased
- 2000-12-11 KR KR1020027007674A patent/KR20020060265A/ko not_active Withdrawn
- 2000-12-11 CA CA002394559A patent/CA2394559C/en not_active Expired - Fee Related
- 2000-12-11 AU AU20844/01A patent/AU2084401A/en not_active Abandoned
- 2000-12-11 DE DE60042560T patent/DE60042560D1/de not_active Expired - Lifetime
- 2000-12-11 EP EP00984176A patent/EP1237607B1/en not_active Expired - Lifetime
- 2000-12-11 EP EP09009018A patent/EP2106817A1/en not_active Withdrawn
- 2000-12-11 ES ES00984176T patent/ES2328219T3/es not_active Expired - Lifetime
- 2000-12-11 JP JP2001544930A patent/JP4680463B2/ja not_active Expired - Fee Related
-
2001
- 2001-08-09 US US09/927,272 patent/US6505622B2/en not_active Expired - Fee Related
-
2010
- 2010-11-17 JP JP2010257038A patent/JP2011078801A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP4680463B2 (ja) | 2011-05-11 |
| US6505622B2 (en) | 2003-01-14 |
| EP2263725A1 (en) | 2010-12-22 |
| CA2394559C (en) | 2009-04-14 |
| EP1237607B1 (en) | 2009-07-15 |
| DE60042560D1 (de) | 2009-08-27 |
| ES2328219T3 (es) | 2009-11-11 |
| US20020017294A1 (en) | 2002-02-14 |
| EP1237607A2 (en) | 2002-09-11 |
| WO2001043794A8 (en) | 2002-08-29 |
| WO2001043794A3 (en) | 2002-02-14 |
| CA2394559A1 (en) | 2001-06-21 |
| WO2001043794A2 (en) | 2001-06-21 |
| EP2106817A1 (en) | 2009-10-07 |
| AU2084401A (en) | 2001-06-25 |
| JP2003516818A (ja) | 2003-05-20 |
| US6302101B1 (en) | 2001-10-16 |
| JP2011078801A (ja) | 2011-04-21 |
| EP1237607A4 (en) | 2006-12-20 |
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Legal Events
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| PA0105 | International application |
Patent event date: 20020614 Patent event code: PA01051R01D Comment text: International Patent Application |
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| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |