KR20000064752A - 중추신경계허혈또는외상의발현후폴리펩티드성장인자를투여하는방법 - Google Patents
중추신경계허혈또는외상의발현후폴리펩티드성장인자를투여하는방법 Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Control Of Electric Motors In General (AREA)
- Control Of Motors That Do Not Use Commutators (AREA)
- Protection Of Generators And Motors (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
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| US62044496A | 1996-03-22 | 1996-03-22 | |
| US8/620,444 | 1996-03-22 | ||
| PCT/US1997/005071 WO1997034618A1 (en) | 1996-03-22 | 1997-03-21 | Administration of polypeptide growth factors following central nervous system ischemia or trauma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20000064752A true KR20000064752A (ko) | 2000-11-06 |
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| KR1019980707507A Ceased KR20000064752A (ko) | 1996-03-22 | 1997-03-21 | 중추신경계허혈또는외상의발현후폴리펩티드성장인자를투여하는방법 |
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| EP (3) | EP0894004B2 (Direct) |
| JP (2) | JP4847634B2 (Direct) |
| KR (1) | KR20000064752A (Direct) |
| CN (1) | CN1181885C (Direct) |
| AT (2) | ATE493141T1 (Direct) |
| AU (2) | AU725341B2 (Direct) |
| CA (2) | CA2249368A1 (Direct) |
| DE (2) | DE69723429T3 (Direct) |
| ES (1) | ES2201287T5 (Direct) |
| WO (2) | WO1997034618A1 (Direct) |
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| US6150328A (en) | 1986-07-01 | 2000-11-21 | Genetics Institute, Inc. | BMP products |
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| EP1770161A3 (en) | 1993-05-12 | 2008-04-23 | Genetics Institute, LLC | BMP-11 compositions |
| US6291206B1 (en) | 1993-09-17 | 2001-09-18 | Genetics Institute, Inc. | BMP receptor proteins |
| WO1995016035A2 (en) | 1993-12-07 | 1995-06-15 | Genetics Institute, Inc. | Bmp-12, bmp-13 and tendon-inducing compositions thereof |
| US6498142B1 (en) * | 1996-05-06 | 2002-12-24 | Curis, Inc. | Morphogen treatment for chronic renal failure |
| WO1998020889A1 (en) * | 1996-11-15 | 1998-05-22 | Creative Biomolecules Inc | Morphogen peptide-induced regeneration of sense perceptory tissues |
| ATE278414T1 (de) | 1997-05-05 | 2004-10-15 | Curis Inc | Therapien zur behandlung von akutem nierenversagen |
| EP1988395A1 (en) * | 1997-05-30 | 2008-11-05 | Curis, Inc. | Methods for evaluating tissue morphogenesis and morphogenic activity |
| WO1999028341A2 (en) * | 1997-12-04 | 1999-06-10 | Creative Biomolecules, Inc. | Maintenance of smooth muscle integrity by morphogenic proteins |
| US20030170213A1 (en) * | 1998-01-23 | 2003-09-11 | Marc F. Charette | Methods and compositions for enhancing cognitive function using morphogenic proteins |
| US7147839B2 (en) | 1998-05-29 | 2006-12-12 | Curis, Inc. | Methods for evaluating tissue morphogenesis and activity |
| DE19837230A1 (de) * | 1998-08-17 | 2000-03-09 | Jean Krutmann | Neurotrophin-4 zur Behandlung von Tumoren neuroektodermalen Ursprungs |
| US6727224B1 (en) | 1999-02-01 | 2004-04-27 | Genetics Institute, Llc. | Methods and compositions for healing and repair of articular cartilage |
| CN1753686A (zh) * | 1999-08-18 | 2006-03-29 | 综合医院公司 | 用于促进从中枢神经系统损伤中恢复的方法、组合物和试剂盒 |
| US6749850B1 (en) | 1999-08-18 | 2004-06-15 | The General Hospital Corporation | Methods, compositions and kits for promoting recovery from damage to the central nervous system |
| EP2286847A1 (en) | 1999-10-15 | 2011-02-23 | Genetics Institute, LLC | Formulations of hyaluronic acid for delivery of osteogenic proteins |
| US7060676B2 (en) * | 1999-12-20 | 2006-06-13 | Trustees Of Tufts College | T. cruzi-derived neurotrophic agents and methods of use therefor |
| US7541184B2 (en) | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| AU2001268147B2 (en) * | 2000-06-01 | 2006-05-04 | Children's Medical Center Corporation | Methods and compositions for producing a neurosalutary effect in a subject |
| US6855690B2 (en) | 2000-06-01 | 2005-02-15 | Children's Medical Center Corporation | Methods and compositions for treating ocular disorders |
| TWI329129B (en) | 2001-02-08 | 2010-08-21 | Wyeth Corp | Modified and stabilized gdf propeptides and uses thereof |
| US7700819B2 (en) | 2001-02-16 | 2010-04-20 | Kci Licensing, Inc. | Biocompatible wound dressing |
| US7763769B2 (en) | 2001-02-16 | 2010-07-27 | Kci Licensing, Inc. | Biocompatible wound dressing |
| ES2305246T3 (es) | 2001-06-01 | 2008-11-01 | Wyeth | Composiciones para la administracion sistemica de secuencias que codifican proteinas oseas morfogeneticas. |
| JP2004528042A (ja) * | 2001-06-01 | 2004-09-16 | エクサイト セラピーズ， インコーポレイテッド | Ｔ細胞誘導性組織修復および再生 |
| TWI267378B (en) | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
| US20060259014A1 (en) | 2002-05-22 | 2006-11-16 | Surgimark, Inc. | Aspirator sleeve and suction handle |
| CA2504287A1 (en) | 2002-11-26 | 2004-06-10 | Nobex Corporation | Natriuretic compounds, conjugates, and uses thereof |
| US20040229292A1 (en) * | 2002-11-26 | 2004-11-18 | Sebastiano Cavallaro | Use of FGF-18 in the diagnosis and treatment of memory disorders |
| WO2004104185A1 (en) | 2003-05-08 | 2004-12-02 | Xcyte Therapies, Inc. | Generation and isolation of antigen-specific t cells |
| US8410246B2 (en) | 2004-06-17 | 2013-04-02 | Thrasos, Inc. | TDF-related compounds and analogs thereof |
| EP1766077B1 (en) * | 2004-06-21 | 2012-03-28 | The Board Of Trustees Of The Leland Stanford Junior University | Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder |
| WO2006012365A2 (en) * | 2004-07-20 | 2006-02-02 | University Of Maryland | Protease inhibitor |
| WO2006011600A1 (ja) * | 2004-07-29 | 2006-02-02 | Anges Mg, Inc. | 脳機能改善のための医薬および方法 |
| US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
| GB0425625D0 (en) * | 2004-11-22 | 2004-12-22 | Royal College Of Surgeons Ie | Treatment of disease |
| PL2497780T3 (pl) | 2005-09-20 | 2015-09-30 | Thrasos Innovation Inc | Związki pokrewne TDF oraz ich analogi |
| AU2006315562C1 (en) | 2005-11-12 | 2013-10-03 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for treating depression using NCAM peptide mimetics |
| AU2007234612B2 (en) * | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
| EP2121142B1 (en) * | 2007-01-25 | 2013-04-03 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH | Use of gdf-5 for the improvement or maintenance of dermal appearance |
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| CA2695697A1 (en) | 2007-08-07 | 2009-02-12 | Advanced Technologies And Regenerative Medicine, Llc | Protein formulations comprising gdf-5 in aqueous acidic solution |
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| JP5819734B2 (ja) * | 2009-02-12 | 2015-11-24 | ストライカー コーポレイションＳｔｒｙｋｅｒ Ｃｏｒｐｏｒａｔｉｏｎ | ＴＧＦ−βスーパーファミリーメンバー含有タンパク質の最小に侵襲性の全身送達のための組成物および方法 |
| SG173632A1 (en) * | 2009-02-12 | 2011-09-29 | Stryker Corp | Peripheral administration of proteins including tgf-beta superfamily members for systemic treatment of disorders and disease |
| JP5749659B2 (ja) | 2009-03-12 | 2015-07-15 | ハーゼ インベストメンツ ウーゲー | Ｂｍｐアンタゴニスト感受性が低下した骨形成タンパク質２（ｂｍｐ２）変異体 |
| US20110002897A1 (en) | 2009-06-11 | 2011-01-06 | Burnham Institute For Medical Research | Directed differentiation of stem cells |
| AU2010295509A1 (en) | 2009-09-17 | 2012-04-19 | Stryker Corporation | Buffers for controlling the pH of bone morphogenetic proteins |
| JP2013514811A (ja) | 2009-12-22 | 2013-05-02 | ストライカー コーポレイション | 免疫原性が抑制されたｂｍｐ−７変異体 |
| CN101822815A (zh) * | 2010-04-29 | 2010-09-08 | 广东八加一医药有限公司 | 系列多肽小分子在制备防治缺血性脑血管疾病药物中的应用 |
| SG187589A1 (en) | 2010-08-20 | 2013-03-28 | Wyeth Llc | Designer osteogenic proteins |
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- 1997-03-21 DE DE69723429T patent/DE69723429T3/de not_active Expired - Lifetime
- 1997-03-21 JP JP53358397A patent/JP4847634B2/ja not_active Expired - Fee Related
- 1997-03-21 JP JP9533791A patent/JP2000507939A/ja not_active Withdrawn
- 1997-03-21 EP EP97917532A patent/EP0894004B2/en not_active Expired - Lifetime
- 1997-03-21 KR KR1019980707507A patent/KR20000064752A/ko not_active Ceased
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- 1997-03-21 AT AT97917532T patent/ATE244574T1/de not_active IP Right Cessation
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| DE69723429T2 (de) | 2004-04-22 |
| US6407060B1 (en) | 2002-06-18 |
| JP2000507939A (ja) | 2000-06-27 |
| ATE244574T1 (de) | 2003-07-15 |
| CN1181885C (zh) | 2004-12-29 |
| US20030022830A1 (en) | 2003-01-30 |
| AU734312B2 (en) | 2001-06-07 |
| DE69740089D1 (de) | 2011-02-10 |
| JP4847634B2 (ja) | 2011-12-28 |
| EP1364655B1 (en) | 2010-12-29 |
| CA2249368A1 (en) | 1997-09-25 |
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| CN1219133A (zh) | 1999-06-09 |
| US20010039261A1 (en) | 2001-11-08 |
| EP0894004B1 (en) | 2003-07-09 |
| CA2249596A1 (en) | 1997-09-25 |
| ATE493141T1 (de) | 2011-01-15 |
| ES2201287T3 (es) | 2004-03-16 |
| AU725341B2 (en) | 2000-10-12 |
| ES2201287T5 (es) | 2007-10-16 |
| JP2000506894A (ja) | 2000-06-06 |
| EP0894004A1 (en) | 1999-02-03 |
| AU2552997A (en) | 1997-10-10 |
| EP0904093A1 (en) | 1999-03-31 |
| AU2582397A (en) | 1997-10-10 |
| EP0904093A4 (en) | 2004-11-17 |
| US6214796B1 (en) | 2001-04-10 |
| WO1997034626A1 (en) | 1997-09-25 |
| DE69723429T3 (de) | 2007-09-20 |
| WO1997034618A1 (en) | 1997-09-25 |
| EP0894004B2 (en) | 2007-02-21 |
| CA2249596C (en) | 2011-11-08 |
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