KR19990067028A - 가용화 방법 - Google Patents

가용화 방법 Download PDF

Info

Publication number
KR19990067028A
KR19990067028A KR1019980702965A KR19980702965A KR19990067028A KR 19990067028 A KR19990067028 A KR 19990067028A KR 1019980702965 A KR1019980702965 A KR 1019980702965A KR 19980702965 A KR19980702965 A KR 19980702965A KR 19990067028 A KR19990067028 A KR 19990067028A
Authority
KR
South Korea
Prior art keywords
solulan
amphiphile
agent
medicament
composition
Prior art date
Application number
KR1019980702965A
Other languages
English (en)
Korean (ko)
Inventor
랜달 찰스 뉴 로저
Original Assignee
코르텍스 (유케이) 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 코르텍스 (유케이) 리미티드 filed Critical 코르텍스 (유케이) 리미티드
Publication of KR19990067028A publication Critical patent/KR19990067028A/ko

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
KR1019980702965A 1995-10-25 1996-10-25 가용화 방법 KR19990067028A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9521805.3A GB9521805D0 (en) 1995-10-25 1995-10-25 Solubilisation methods
GB9521805.3 1995-10-25
PCT/GB1996/002609 WO1997015289A1 (en) 1995-10-25 1996-10-25 Solubilisation methods

Publications (1)

Publication Number Publication Date
KR19990067028A true KR19990067028A (ko) 1999-08-16

Family

ID=10782854

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019980702965A KR19990067028A (ko) 1995-10-25 1996-10-25 가용화 방법

Country Status (12)

Country Link
EP (1) EP0857061A1 (ja)
JP (1) JP2000502990A (ja)
KR (1) KR19990067028A (ja)
CN (1) CN1202818A (ja)
AU (1) AU704292B2 (ja)
BR (1) BR9611343A (ja)
CA (1) CA2235487A1 (ja)
GB (1) GB9521805D0 (ja)
NO (1) NO981864L (ja)
NZ (1) NZ320442A (ja)
WO (1) WO1997015289A1 (ja)
ZA (1) ZA969016B (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9605709D0 (en) * 1996-03-19 1996-05-22 Cortecs Ltd Method
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
CN101453982B (zh) 2006-05-30 2011-05-04 精达制药公司 两件式内部通道渗透递送系统流动调节器
WO2008021133A2 (en) 2006-08-09 2008-02-21 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
EP2157967B1 (en) 2007-04-23 2013-01-16 Intarcia Therapeutics, Inc Suspension formulations of insulinotropic peptides and uses thereof
EP2240155B1 (en) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Devices, formulations, and methods for delivery of multiple beneficial agents
CN104323981B (zh) 2009-09-28 2019-03-12 精达制药公司 基本稳态药物递送的快速建立和/或终止
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
WO2016196851A2 (en) 2015-06-03 2016-12-08 Intarcia Therapeutics, Inc. Implant placement and removal systems
MX2018014016A (es) 2016-05-16 2019-08-01 Intarcia Therapeutics Inc Polipéptidos selectivos del receptor de glucagón y métodos para utilizarlos.
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
CN110225762A (zh) 2017-01-03 2019-09-10 因塔西亚制药公司 包括glp-1受体激动剂的连续施用和药物的共同施用的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0012115A1 (de) * 1978-12-04 1980-06-11 Ciba-Geigy Ag Pharmazeutische Präparate zur topischen Behandlung von Virusinfektionen
US4411882A (en) * 1978-12-21 1983-10-25 Sandoz Ltd. Galenical compositions

Also Published As

Publication number Publication date
EP0857061A1 (en) 1998-08-12
BR9611343A (pt) 1999-12-28
WO1997015289A1 (en) 1997-05-01
NO981864D0 (no) 1998-04-24
ZA969016B (en) 1998-04-28
JP2000502990A (ja) 2000-03-14
NZ320442A (en) 1999-10-28
AU7317896A (en) 1997-05-15
CA2235487A1 (en) 1997-05-01
GB9521805D0 (en) 1996-01-03
CN1202818A (zh) 1998-12-23
NO981864L (no) 1998-06-24
AU704292B2 (en) 1999-04-15

Similar Documents

Publication Publication Date Title
KR19990067028A (ko) 가용화 방법
US6258377B1 (en) Hydrophobic preparations containing medium chain monoglycerides
DE69231507T2 (de) Verfahren zur Zubereitung von biologisch aktiven Komponenten enthaltenden Mikrospheren
EP0686045B1 (en) Excipient stabilization of polypeptides treated with organic solvents
AU600246B2 (en) Stabilised human tissue plasminogen activator compositions
KR20030078740A (ko) 파클리탁셀을 기본으로 하는 개선된 항종양 조성물
EP0197987A1 (de) Verfahren zur herstellung von lösungen von umgekehrten mizellen.
GB2359747A (en) An anaesthetic formulation comprising micelles and propofol
EA034565B1 (ru) Композиции левосимендана для внутривенного введения в виде инфузии или инъекции и концентрата для инфузии
CN102764240B (zh) 一种前列地尔冻干微乳及其制备方法和应用
TW200536557A (en) Articles comprising formulations for protection of PEG-interferon alpha conjugates
Wichert et al. Low molecular weight PLA: a suitable polymer for pulmonary administered microparticles?
JP2003507388A (ja) 凍結乾燥したケーキの安定化
US8680061B2 (en) Medicinal forms of phospholipid preparations and methods for their preparation
JPH0741422A (ja) γ−オリザノールの水への可溶化方法
JP2758297B2 (ja) リポソーム調製物
US20040254129A1 (en) Use of ethoxylated phytosterols and phytostanols
DK168655B1 (da) Frysetørret parenteralt præparat indeholdende phenylquinolincarboxylsyrer
ES2929437T3 (es) Método para preparación de nanopartículas
RU2500396C2 (ru) Средство, обладающее кардиопротекторным действием, и способ его получения
JPH10510207A (ja) 隔離剤
CN110339349A (zh) 一种重组人尿激酶原组合物及其制备方法
Goel et al. Pharmaceutical excipients
KR100433363B1 (ko) 아시클로버함유 외용필름형성 하이드로겔 제제
JPS61207327A (ja) 安定な混合ビタミン凍結乾燥製剤の製法

Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid