KR102770786B1 - 항-tigit 항체 단독의, 및 프로그램화된 사멸 수용체 1 (pd-1) 항체와 조합된 항-tigit 항체의 안정한 제제 및 그의 사용 방법 - Google Patents

항-tigit 항체 단독의, 및 프로그램화된 사멸 수용체 1 (pd-1) 항체와 조합된 항-tigit 항체의 안정한 제제 및 그의 사용 방법 Download PDF

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KR102770786B1
KR102770786B1 KR1020197035375A KR20197035375A KR102770786B1 KR 102770786 B1 KR102770786 B1 KR 102770786B1 KR 1020197035375 A KR1020197035375 A KR 1020197035375A KR 20197035375 A KR20197035375 A KR 20197035375A KR 102770786 B1 KR102770786 B1 KR 102770786B1
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알납 데
차크라바르티 나추 나라시만
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머크 샤프 앤드 돔 엘엘씨
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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KR1020197035375A 2017-05-02 2018-05-01 항-tigit 항체 단독의, 및 프로그램화된 사멸 수용체 1 (pd-1) 항체와 조합된 항-tigit 항체의 안정한 제제 및 그의 사용 방법 Active KR102770786B1 (ko)

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US201762500278P 2017-05-02 2017-05-02
US62/500,278 2017-05-02
PCT/US2018/030516 WO2018204405A1 (en) 2017-05-02 2018-05-01 Stable formulations of anti-tigit antibodies alone and in combination with programmed death receptor 1 (pd-1) antibodies and methods of use thereof

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KR102770786B1 true KR102770786B1 (ko) 2025-02-20

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EP (1) EP3618855A4 (enExample)
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CN (1) CN110603052A (enExample)
AU (1) AU2018261080A1 (enExample)
BR (1) BR112019022698A2 (enExample)
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SG11201909941QA (en) 2019-11-28
CA3061050A1 (en) 2018-11-08
EP3618855A1 (en) 2020-03-11
US20200354453A1 (en) 2020-11-12
BR112019022698A2 (pt) 2020-05-19
IL270175A (enExample) 2019-12-31
JP7402693B2 (ja) 2023-12-21
IL270175B1 (en) 2023-05-01
AU2018261080A1 (en) 2019-11-07
RU2019138519A (ru) 2021-06-02
CO2019012356A2 (es) 2020-01-17
EP3618855A4 (en) 2021-02-17
CL2019003145A1 (es) 2020-07-10
SG10202111905PA (en) 2021-12-30
RU2019138519A3 (enExample) 2021-08-30
US20240182573A1 (en) 2024-06-06
MA50661A (fr) 2020-08-05
JP2020518600A (ja) 2020-06-25
MX2019013033A (es) 2020-02-05
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