KR102713511B1 - 세균성 질증의 치료를 위한 락토바실러스 람노서스 박테리아 - Google Patents

세균성 질증의 치료를 위한 락토바실러스 람노서스 박테리아 Download PDF

Info

Publication number
KR102713511B1
KR102713511B1 KR1020187000096A KR20187000096A KR102713511B1 KR 102713511 B1 KR102713511 B1 KR 102713511B1 KR 1020187000096 A KR1020187000096 A KR 1020187000096A KR 20187000096 A KR20187000096 A KR 20187000096A KR 102713511 B1 KR102713511 B1 KR 102713511B1
Authority
KR
South Korea
Prior art keywords
nutritional
pharmaceutical composition
strain
vaginal
bpl005
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020187000096A
Other languages
English (en)
Korean (ko)
Other versions
KR20180021777A (ko
Inventor
꾸아드로스 마리아 엠빠르 체놀
라모 베아뜨리스 까시노스
앙굴로 안젤라 실바
비달 다니엘 라몬
마르티네즈 살바도르 헤노베스
Original Assignee
훼링 비.브이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 훼링 비.브이. filed Critical 훼링 비.브이.
Publication of KR20180021777A publication Critical patent/KR20180021777A/ko
Application granted granted Critical
Publication of KR102713511B1 publication Critical patent/KR102713511B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/175—Rhamnosus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Animal Husbandry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
KR1020187000096A 2015-06-29 2016-06-29 세균성 질증의 치료를 위한 락토바실러스 람노서스 박테리아 Active KR102713511B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15174222 2015-06-29
EP15174222.8 2015-06-29
PCT/EP2016/065074 WO2017001440A1 (en) 2015-06-29 2016-06-29 Lactobacillus rhamnosus bacterium for treatment of e.g. bacterial vaginosis

Publications (2)

Publication Number Publication Date
KR20180021777A KR20180021777A (ko) 2018-03-05
KR102713511B1 true KR102713511B1 (ko) 2024-10-04

Family

ID=53496506

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020187000096A Active KR102713511B1 (ko) 2015-06-29 2016-06-29 세균성 질증의 치료를 위한 락토바실러스 람노서스 박테리아

Country Status (9)

Country Link
US (2) US10588926B2 (https=)
JP (1) JP6837015B2 (https=)
KR (1) KR102713511B1 (https=)
CN (2) CN108076643B (https=)
AU (1) AU2016287200B2 (https=)
CA (1) CA2989977A1 (https=)
MX (1) MX383921B (https=)
RU (1) RU2758109C2 (https=)
WO (1) WO2017001440A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX383921B (es) 2015-06-29 2025-03-14 Ferring Bv Bacteria lactobacillus rhamnosus para el tratamiento de, por ejemplo, vaginosis bacteriana.
EP3427745A1 (en) 2017-07-12 2019-01-16 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO New probiotic composition for prevention of bacterial vaginosis
CN108004188B (zh) * 2018-01-11 2020-02-14 广东龙创基药业有限公司 一种鼠李糖乳杆菌及其用于制备阴道抑菌药物的应用
RU2703708C1 (ru) * 2018-10-08 2019-10-21 Федеральное государственное бюджетное образовательное учреждение высшего образования "Курский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ прогнозирования степени риска нарушения микробиоты влагалища
AU2021284269A1 (en) * 2020-06-01 2023-01-05 Ferring B.V. Vaginal microbiota compositions
PL4165220T3 (pl) * 2020-06-11 2024-11-18 ADM Denmark A/S Kompozycja probiotyczna i jej zastosowanie przeciwko infekcjom candida
ES2983665T3 (es) * 2020-07-14 2024-10-24 Probisearch S L U Cepa de Lactobacillus salivarus PS11610 y su uso en la prevención y el tratamiento de disbiosis del aparato urogenital
KR102546934B1 (ko) 2021-04-02 2023-06-23 대한민국 락토바실러스 람노서스 kcc-51 균주 및 이를 포함하는 조성물
CN113287753A (zh) * 2021-05-24 2021-08-24 国珍健康科技（北京）有限公司 一种用于改善女性阴道炎症的益生菌组合物
CN115252655B (zh) * 2022-07-14 2023-06-16 金华银河生物科技有限公司 用于改善阴道炎症的益生菌后生元制品及制备方法和应用
CN115569154B (zh) * 2022-09-21 2024-06-11 微康益生菌(苏州)股份有限公司 防治念珠菌阴道炎的鼠李糖乳杆菌LRa05及其应用
CN118077903B (zh) * 2024-03-27 2024-09-17 瀚天生物(北京)科技有限公司 一种用于女性改善阴道紧致和水润环境的口服益生菌复合制剂及其制备方法与应用
WO2025210272A1 (en) * 2024-04-05 2025-10-09 Ferring B.V. Composition comprising lactobacillus species for vaginal therapies

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002523372A (ja) 1998-08-24 2002-07-30 ガネデン バイオテック， インコーポレイテッド 共生乳酸産生細菌およびその使用
WO2012035028A1 (en) 2010-09-14 2012-03-22 Hso Health Care Gmbh Compositions for the vaginal and oral administration of lactobacillus and uses thereof
JP2012512828A (ja) * 2008-12-18 2012-06-07 ブラッコ・イメージング・ソシエタ・ペル・アチオニ プロバイオティック製剤

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8603338D0 (sv) 1986-08-07 1986-08-07 Bjorn Andersch Medel for behandling av tillstand i slidan
FR2672300B1 (fr) * 1991-02-01 1994-09-23 Agronomique Inst Nat Rech Xylanase, souches de bacillus productrices de xylanase et leurs utilisations.
US5733568A (en) * 1993-12-03 1998-03-31 Lafor Laboratories Limited Micro-encapsulated lactobacilli for medical applications
ATE207755T1 (de) * 1998-04-30 2001-11-15 Vesely Renata Maria Cavaliere Pharmazeutische zusammensetzungen enthaltend lactobacillus brevis und lactobacillus salivarius zur behandlung von vaginainfektionen
EP1137423B1 (en) * 1998-12-11 2005-03-09 Urex Biotech, Inc. Oral administration of lactobacillus for the treatment and prevention of urogenital infection
US20020044926A1 (en) * 1999-12-10 2002-04-18 Gregor Reid Oral administration of lactobacillus for the treatment and prevention of urogenital infection
SE521022C2 (sv) * 2001-09-20 2003-09-23 Ellen Ab Mjölksyraproducerande bakterier för användning som probiotiska organismer i vaginan hos människa
US20040022775A1 (en) * 2002-04-15 2004-02-05 Gregor Reid Methods of treating viral infections in mammals
US20090028839A1 (en) * 2004-12-23 2009-01-29 Tchikindas Mikhail L Compositions and methods for the prophylaxis and treatment of vaginal infections
ES2348403T3 (es) * 2005-02-15 2010-12-03 Barry R. Goldin Un alimento que contiene un probiotico y un beta-glucano aislado y metodos de uso del mismo.
EP2216036A1 (en) * 2009-02-10 2010-08-11 Nestec S.A. Lactobacillus rhamnosus NCC4007, a probiotic mixture and weight control
IT1403661B1 (it) * 2011-01-28 2013-10-31 Probiotical Spa Composizione effervescente in forma solida per uso in applicazioni vaginali per il trattamento di infezioni vaginali.
CN102835657B (zh) * 2011-06-20 2014-08-20 丰华生物科技股份有限公司 用以抑制发炎反应及抗阴道炎的含乳酸菌食品组合物及医药组合物
CN104284975B (zh) * 2012-04-09 2016-08-24 科.汉森有限公司 应用鼠李糖乳杆菌菌株的生物保护
FR2992861B1 (fr) * 2012-07-09 2014-10-17 Probionov Utilisation de thiosulfate pour potentialiser l'effet anti-pathogene des lactobacilles
US20140234259A1 (en) * 2012-12-11 2014-08-21 Suzanah Juras Natural Intra-Vaginal Inserts to Control Imbalanced pH
CN103409334B (zh) * 2013-01-16 2018-07-20 生合生物科技股份有限公司 抑制阴道炎病原菌之乳酸杆菌及其用途
JP6110240B2 (ja) * 2013-04-10 2017-04-05 国立大学法人広島大学 乳酸菌の菌体等、並びにこれらを含有する口腔内疾患の予防材等及び食品
RU2570622C2 (ru) * 2013-10-24 2015-12-10 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" ШТАММ Lactobacillus rhamnosus, ОБЛАДАЮЩИЙ АНТИБАКТЕРИАЛЬНОЙ И АНТИГРИБКОВОЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ ПАТОГЕННОЙ И УСЛОВНО-ПАТОГЕННОЙ ВАГИНАЛЬНОЙ МИКРОФЛОРЫ
MX383921B (es) 2015-06-29 2025-03-14 Ferring Bv Bacteria lactobacillus rhamnosus para el tratamiento de, por ejemplo, vaginosis bacteriana.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002523372A (ja) 1998-08-24 2002-07-30 ガネデン バイオテック， インコーポレイテッド 共生乳酸産生細菌およびその使用
JP2012512828A (ja) * 2008-12-18 2012-06-07 ブラッコ・イメージング・ソシエタ・ペル・アチオニ プロバイオティック製剤
WO2012035028A1 (en) 2010-09-14 2012-03-22 Hso Health Care Gmbh Compositions for the vaginal and oral administration of lactobacillus and uses thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FEMS Immunology Medical Microbiology.,35:131-134(2003.1.1.)
Journal of Infectious Disease.,183:s77-s80(2001.3.1.)

Also Published As

Publication number Publication date
WO2017001440A1 (en) 2017-01-05
AU2016287200A1 (en) 2018-01-18
JP2018520677A (ja) 2018-08-02
CN108076643B (zh) 2021-09-21
US11202813B2 (en) 2021-12-21
CA2989977A1 (en) 2017-01-05
US10588926B2 (en) 2020-03-17
KR20180021777A (ko) 2018-03-05
US20200268815A1 (en) 2020-08-27
RU2017143465A (ru) 2019-08-01
RU2758109C2 (ru) 2021-10-26
MX2017016748A (es) 2018-11-09
CN108076643A (zh) 2018-05-25
JP6837015B2 (ja) 2021-03-03
AU2016287200B2 (en) 2020-09-17
RU2017143465A3 (https=) 2019-11-20
US20180228850A1 (en) 2018-08-16
CN113564075A (zh) 2021-10-29
MX383921B (es) 2025-03-14

Similar Documents

Publication Publication Date Title
KR102713511B1 (ko) 세균성 질증의 치료를 위한 락토바실러스 람노서스 박테리아
US8846027B2 (en) Compositions for the vaginal and oral administration of Lactobacillus and uses thereof
US9649347B2 (en) Protective effects and application of a Lactobacillus rhamnosus on the alleviation of chronic alcoholic liver injury
KR101867048B1 (ko) 질 내 병원성 미생물에 대한 증식억제활성을 갖는 락토바실러스 속 균주
KR100686558B1 (ko) 체지방 저하 기능성 락토바실러스 플랜타륨와 이를 함유한 식품
JP3940929B2 (ja) コレステロールを低下および同化する能力を有する酸および胆汁酸塩耐性のＬａｃｔｏｂａｃｉｌｌｕｓ分離株
CN105567586A (zh) 一株具有抗糖尿病功能的植物乳杆菌及其应用
EP3808357B1 (en) Composition comprising megamonas funiformis and anaerofustis stercorihominis and use thereof
CN116064313B (zh) 植物乳杆菌ccfm1281在缓解运动性疲劳中的应用
CN117159598B (zh) 植物乳植杆菌Lp18在制备增强免疫的药物或保健食品方面的用途及产品
KR102036275B1 (ko) 항-염증 활성이 우수한 페디오코커스 악시딜락티시 ldtm 5201 신균주(kctc 13563bp)
CN113528367B (zh) 一株具有预防腹泻和降解胆固醇功能的凝结芽孢杆菌
KR20240132177A (ko) 항이상지질혈증 활성을 갖는 신규 락티플란티바실러스 플란타룸 균주 및 이의 용도
EP3313424B1 (en) Lactobacillus rhamnosus bacterium for treatment of e.g. bacterial vaginosis
KR102807100B1 (ko) 히스타민 분해능을 가지는 락티플란티바실러스 플란타룸 균주
KR20200128887A (ko) 위장관 운동 장애 질환 개선, 치료 또는 예방용 김치 유산균 조성물
KR20260039972A (ko) 신규한 바실러스 벨레젠시스 균주 및 이의 용도
CN116445352A (zh) 一种副干酪乳杆菌（Lacticaseibacillus paracasei）HCLP01及其在制备具有抗氧化或抗衰老作用的产品中的应用

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20180102

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20210503

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20231019

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20240814

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20240930

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20240930

End annual number: 3

Start annual number: 1

PG1601 Publication of registration