KR102575347B1 - 신규한 다이아릴프로판다이논 유도체 화합물, 이의 제조방법 및 이를 포함하는 염증 또는 알레르기 질환의 예방 또는 치료용 약학 조성물 - Google Patents

신규한 다이아릴프로판다이논 유도체 화합물, 이의 제조방법 및 이를 포함하는 염증 또는 알레르기 질환의 예방 또는 치료용 약학 조성물 Download PDF

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KR102575347B1
KR102575347B1 KR1020220055563A KR20220055563A KR102575347B1 KR 102575347 B1 KR102575347 B1 KR 102575347B1 KR 1020220055563 A KR1020220055563 A KR 1020220055563A KR 20220055563 A KR20220055563 A KR 20220055563A KR 102575347 B1 KR102575347 B1 KR 102575347B1
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South Korea
Prior art keywords
inflammatory
formula
compound
preventing
pharmaceutically acceptable
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KR1020220055563A
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English (en)
Korean (ko)
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강태봉
이광호
서승용
비상
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엘림랜드 주식회사
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Priority to KR1020220055563A priority Critical patent/KR102575347B1/ko
Priority to PCT/KR2023/004942 priority patent/WO2023214706A1/fr
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Publication of KR102575347B1 publication Critical patent/KR102575347B1/ko

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/54Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/304Foods, ingredients or supplements having a functional effect on health having a modulation effect on allergy and risk of allergy
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/324Foods, ingredients or supplements having a functional effect on health having an effect on the immune system
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00Food ingredients
    • A23V2250/30Other Organic compounds

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020220055563A 2022-05-04 2022-05-04 신규한 다이아릴프로판다이논 유도체 화합물, 이의 제조방법 및 이를 포함하는 염증 또는 알레르기 질환의 예방 또는 치료용 약학 조성물 KR102575347B1 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020220055563A KR102575347B1 (ko) 2022-05-04 2022-05-04 신규한 다이아릴프로판다이논 유도체 화합물, 이의 제조방법 및 이를 포함하는 염증 또는 알레르기 질환의 예방 또는 치료용 약학 조성물
PCT/KR2023/004942 WO2023214706A1 (fr) 2022-05-04 2023-04-12 Nouveau composé dérivé de diaryl-propanedione, son procédé de préparation et composition pharmaceutique le comprenant pour la prévention ou le traitement de maladies inflammatoires ou allergiques

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020220055563A KR102575347B1 (ko) 2022-05-04 2022-05-04 신규한 다이아릴프로판다이논 유도체 화합물, 이의 제조방법 및 이를 포함하는 염증 또는 알레르기 질환의 예방 또는 치료용 약학 조성물

Publications (1)

Publication Number Publication Date
KR102575347B1 true KR102575347B1 (ko) 2023-09-08

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KR1020220055563A KR102575347B1 (ko) 2022-05-04 2022-05-04 신규한 다이아릴프로판다이논 유도체 화합물, 이의 제조방법 및 이를 포함하는 염증 또는 알레르기 질환의 예방 또는 치료용 약학 조성물

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KR (1) KR102575347B1 (fr)
WO (1) WO2023214706A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003076407A1 (fr) * 2002-03-14 2003-09-18 The Walter And Eliza Hall Institute Of Medical Research Nouveaux derives de chalcone et leurs utilisations
KR20110022589A (ko) * 2008-05-08 2011-03-07 노바 사우쓰이스턴 유니버시티 혈관 내피 성장 인자 수용체에 대한 특이적 억제제
KR101808950B1 (ko) 2016-07-27 2017-12-13 충북대학교 산학협력단 디메톡시페닐 유도체, 이의 제조방법 및 이를 포함하는 항염증 및 피부 미백용 조성물
KR20200071409A (ko) * 2018-12-11 2020-06-19 건국대학교 글로컬산학협력단 우엉 추출물을 유효성분으로 함유하는 nlrp3 인플라마좀의 과활성에 의한 만성 염증질환의 개선, 예방 또는 치료용 조성물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7875603B2 (en) * 2006-09-21 2011-01-25 Nova Southeastern University Specific inhibitors for vascular endothelial growth factor receptors

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003076407A1 (fr) * 2002-03-14 2003-09-18 The Walter And Eliza Hall Institute Of Medical Research Nouveaux derives de chalcone et leurs utilisations
KR20110022589A (ko) * 2008-05-08 2011-03-07 노바 사우쓰이스턴 유니버시티 혈관 내피 성장 인자 수용체에 대한 특이적 억제제
KR101808950B1 (ko) 2016-07-27 2017-12-13 충북대학교 산학협력단 디메톡시페닐 유도체, 이의 제조방법 및 이를 포함하는 항염증 및 피부 미백용 조성물
KR20200071409A (ko) * 2018-12-11 2020-06-19 건국대학교 글로컬산학협력단 우엉 추출물을 유효성분으로 함유하는 nlrp3 인플라마좀의 과활성에 의한 만성 염증질환의 개선, 예방 또는 치료용 조성물

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Bioorganic & Medicinal Chemistry, Vol. 15, pp. 3290-3298(2007.2.11.)* *

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