KR102547565B1 - 호염기구 활성화 검사 방법 - Google Patents
호염기구 활성화 검사 방법 Download PDFInfo
- Publication number
- KR102547565B1 KR102547565B1 KR1020180091151A KR20180091151A KR102547565B1 KR 102547565 B1 KR102547565 B1 KR 102547565B1 KR 1020180091151 A KR1020180091151 A KR 1020180091151A KR 20180091151 A KR20180091151 A KR 20180091151A KR 102547565 B1 KR102547565 B1 KR 102547565B1
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- South Korea
- Prior art keywords
- basophil
- basophils
- ligand
- activated
- allergen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Ecology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Physiology (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Zoology (AREA)
- Virology (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17001352.8 | 2017-08-08 | ||
| EP17001352.8A EP3441763A1 (de) | 2017-08-08 | 2017-08-08 | Verfahren zum nachweis einer basophilenaktivierung |
| EP17001979.8 | 2017-12-05 | ||
| EP17001979 | 2017-12-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20190016446A KR20190016446A (ko) | 2019-02-18 |
| KR102547565B1 true KR102547565B1 (ko) | 2023-06-26 |
Family
ID=63041937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020180091151A Active KR102547565B1 (ko) | 2017-08-08 | 2018-08-06 | 호염기구 활성화 검사 방법 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11119109B2 (https=) |
| EP (1) | EP3441765B1 (https=) |
| JP (1) | JP7265325B2 (https=) |
| KR (1) | KR102547565B1 (https=) |
| CN (1) | CN109387636B (https=) |
| AU (1) | AU2018213977B2 (https=) |
| BR (1) | BR102018015288A2 (https=) |
| CA (1) | CA3012989C (https=) |
| DE (1) | DE102018006212A1 (https=) |
| ES (1) | ES2904354T3 (https=) |
| LT (1) | LT3441765T (https=) |
| PL (1) | PL3441765T3 (https=) |
| SG (1) | SG10201806697RA (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210382070A1 (en) * | 2020-06-04 | 2021-12-09 | The Chinese University Of Hong Kong | Diagnostic biomarkers for shrimp allergy |
| CN112630423A (zh) * | 2020-12-31 | 2021-04-09 | 杭州福德敏生物技术有限公司 | 一种小麦免疫荧光检测试纸条及应用 |
| KR102497904B1 (ko) * | 2021-02-10 | 2023-02-10 | 재단법인 아산사회복지재단 | 세포 원심분리 및 농축을 이용한 면역세포 검출 방법 및 면역세포 검출용 칩 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003025566A2 (en) | 2001-09-17 | 2003-03-27 | Imumed S.R.O. | A method and kit for the measurement of the activation of basophils induced by allergen to determine hypersensitivity |
| WO2012105541A1 (ja) * | 2011-01-31 | 2012-08-09 | 大鵬薬品工業株式会社 | 新規ヒノキ花粉アレルゲン |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3132491A1 (de) | 1980-08-22 | 1982-07-01 | Laboratorium Prof. Dr. Rudolf Berthold, 7547 Wildbad | Verfahren zur durchfuehrung analytischer bestimmungen mittels der chemilumineszenzmethode und anwendung des verfahrens fuer immunassays |
| US4902613A (en) | 1984-05-14 | 1990-02-20 | Becton, Dickinson And Company | Lysing agent for analysis of peripheral blood cells |
| DE3587636T2 (de) | 1984-05-31 | 1994-03-10 | Coulter Corp | Reagenssystem und verfahren zum nachweis, aufzählen und prüfen der klassen und unterklassen von blutleukozyten. |
| US6835551B2 (en) | 1997-01-20 | 2004-12-28 | Orpegen Pharma Gmbh | Basophil degranulation test |
| FR2778413B1 (fr) | 1998-05-07 | 2000-08-04 | Immunotech Sa | Nouveaux reactifs et methode de lyse des erythrocytes |
| DE10235310B4 (de) | 2002-08-01 | 2012-05-16 | Molecular And Clinical Drug Research | Verfahren zur Bestimmung allergener Potenz von Produkten |
| RU2289138C2 (ru) * | 2004-12-14 | 2006-12-10 | Научно-исследовательский институт микробиологии Министерства обороны Российской Федерации | Способ аллергодиагностики по показателям хемилюминесцентного свечения нейтрофилов |
| EP2037269B1 (en) * | 2007-09-11 | 2014-04-02 | Bühlmann Laboratories AG | Allergy test based on flow cytometric analysis |
| JP2009236798A (ja) | 2008-03-28 | 2009-10-15 | Sysmex Corp | 好塩基球の分類計数方法 |
| US20100167317A1 (en) * | 2008-08-05 | 2010-07-01 | Institut Pasteur | Process for enriching basophils in a blood sample |
| WO2012028167A2 (en) | 2010-05-20 | 2012-03-08 | Innohyphen Bv | Acridinium ester chemiluminescence upon reductive triggering |
| US20120083007A1 (en) | 2010-10-01 | 2012-04-05 | Nadeau Kari C | Basophil Activation Based Allergy Diagnostic Test |
| WO2014066271A1 (en) * | 2012-10-22 | 2014-05-01 | Becton, Dickinson And Company | Non-b-lineage cells capable of producing antibody |
| PL3051928T3 (pl) | 2015-01-29 | 2019-07-31 | Kjellberg-Stiftung | Palnik plazmowy |
| CN104677810B (zh) * | 2015-01-30 | 2017-08-22 | 广东医学院附属医院 | 嗜碱性粒细胞活化的检测试剂盒及其使用方法 |
| CN104777303B (zh) * | 2015-04-29 | 2017-02-01 | 何韶衡 | 一种嗜碱性粒细胞激活、脱颗粒的鉴定方法 |
| EP3196209B1 (en) | 2016-01-25 | 2019-10-23 | Euroimmun Medizinische Labordiagnostika AG | A macadamia allergen |
| EP3244212A1 (en) | 2017-02-15 | 2017-11-15 | Euroimmun Medizinische Labordiagnostika AG | An improved assay for the diagnosis of peanut allergy |
-
2018
- 2018-07-26 BR BR102018015288-2A patent/BR102018015288A2/pt unknown
- 2018-08-01 CA CA3012989A patent/CA3012989C/en active Active
- 2018-08-06 JP JP2018147570A patent/JP7265325B2/ja active Active
- 2018-08-06 AU AU2018213977A patent/AU2018213977B2/en active Active
- 2018-08-06 SG SG10201806697RA patent/SG10201806697RA/en unknown
- 2018-08-06 KR KR1020180091151A patent/KR102547565B1/ko active Active
- 2018-08-06 US US16/055,936 patent/US11119109B2/en active Active
- 2018-08-07 DE DE102018006212.1A patent/DE102018006212A1/de not_active Withdrawn
- 2018-08-07 ES ES18187647T patent/ES2904354T3/es active Active
- 2018-08-07 LT LTEP18187647.5T patent/LT3441765T/lt unknown
- 2018-08-07 PL PL18187647T patent/PL3441765T3/pl unknown
- 2018-08-07 EP EP18187647.5A patent/EP3441765B1/de active Active
- 2018-08-08 CN CN201810893515.7A patent/CN109387636B/zh active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003025566A2 (en) | 2001-09-17 | 2003-03-27 | Imumed S.R.O. | A method and kit for the measurement of the activation of basophils induced by allergen to determine hypersensitivity |
| JP2005509845A (ja) | 2001-09-17 | 2005-04-14 | イムメド エス.アール.オー. | ある物質に対する過敏症を判定するための、アレルゲンによって誘起された好塩基球の賦活化の測定のための方法およびキット |
| WO2012105541A1 (ja) * | 2011-01-31 | 2012-08-09 | 大鵬薬品工業株式会社 | 新規ヒノキ花粉アレルゲン |
Non-Patent Citations (2)
| Title |
|---|
| Blank Simon et al, Journal of Immunology (2010.03.), vol 184(9), pp 5403-5413. |
| T Saarne et al, Clin Exp Allergy (2005.), vol 35(3), pp 657-663. |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018213977A1 (en) | 2019-02-28 |
| AU2018213977B2 (en) | 2025-02-20 |
| CA3012989C (en) | 2026-02-10 |
| US20190049461A1 (en) | 2019-02-14 |
| BR102018015288A2 (pt) | 2021-11-09 |
| DE102018006212A1 (de) | 2019-02-14 |
| CA3012989A1 (en) | 2019-02-08 |
| JP2019032317A (ja) | 2019-02-28 |
| LT3441765T (lt) | 2022-01-10 |
| KR20190016446A (ko) | 2019-02-18 |
| EP3441765A1 (de) | 2019-02-13 |
| US11119109B2 (en) | 2021-09-14 |
| EP3441765B1 (de) | 2021-10-20 |
| CN109387636A (zh) | 2019-02-26 |
| SG10201806697RA (en) | 2019-03-28 |
| PL3441765T3 (pl) | 2022-02-14 |
| JP7265325B2 (ja) | 2023-04-26 |
| ES2904354T3 (es) | 2022-04-04 |
| CN109387636B (zh) | 2023-07-04 |
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