KR102546875B1 - 공학처리된 ｆｃ 작제물과 관련된 조성물 및 방법 - Google Patents

공학처리된 ｆｃ 작제물과 관련된 조성물 및 방법 Download PDF

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KR102546875B1
KR102546875B1 KR1020167029772A KR20167029772A KR102546875B1 KR 102546875 B1 KR102546875 B1 KR 102546875B1 KR 1020167029772 A KR1020167029772 A KR 1020167029772A KR 20167029772 A KR20167029772 A KR 20167029772A KR 102546875 B1 KR102546875 B1 KR 102546875B1
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KR20160147762A (ko
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카를로스 제이. 보스퀘스
제임스 에스. 휴스턴
조나단 씨. 랜싱
레오나 이. 링
제임스 미도르
다니엘 오리츠
로라 루티츠키
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모멘타 파머슈티컬스 인코포레이티드
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/08—Antiallergic agents
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
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    • C07K—PEPTIDES
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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KR1020167029772A 2014-05-02 2015-05-01 공학처리된 ｆｃ 작제물과 관련된 조성물 및 방법 Active KR102546875B1 (ko)

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US201461987863P 2014-05-02 2014-05-02
US61/987,863 2014-05-02
US201462081923P 2014-11-19 2014-11-19
US62/081,923 2014-11-19
PCT/US2015/028926 WO2015168643A2 (en) 2014-05-02 2015-05-01 Compositions and methods related to engineered fc constructs

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KR20160147762A KR20160147762A (ko) 2016-12-23
KR102546875B1 true KR102546875B1 (ko) 2023-06-26

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US (4) US10239944B2 (https=)
EP (2) EP4299595A3 (https=)
JP (3) JP2017518965A (https=)
KR (1) KR102546875B1 (https=)
CN (2) CN106661125B (https=)
AU (2) AU2015252866B2 (https=)
CA (1) CA2941072A1 (https=)
DK (1) DK3137506T5 (https=)
ES (1) ES2962694T3 (https=)
IL (3) IL286367B2 (https=)
PL (1) PL3137506T3 (https=)
SG (2) SG11201607070VA (https=)
WO (1) WO2015168643A2 (https=)

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