KR102513343B1 - sGC 자극제의 인 전구약물 - Google Patents

sGC 자극제의 인 전구약물 Download PDF

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KR102513343B1
KR102513343B1 KR1020197003458A KR20197003458A KR102513343B1 KR 102513343 B1 KR102513343 B1 KR 102513343B1 KR 1020197003458 A KR1020197003458 A KR 1020197003458A KR 20197003458 A KR20197003458 A KR 20197003458A KR 102513343 B1 KR102513343 B1 KR 102513343B1
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disease
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compound
pulmonary
hypertension
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KR20190026841A (ko
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제임즈 에드워드 쉐펙
폴 앨런 레노위
아라 머메리언
티모시 클라우드 바든
글렌 로버트 레니
라제쉬 알. 아이옌가
타카시 나카이
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사이클리온 테라퓨틱스, 인크.
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

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  • Diabetes (AREA)
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  • Obesity (AREA)
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  • Urology & Nephrology (AREA)
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KR1020197003458A 2016-07-07 2017-07-06 sGC 자극제의 인 전구약물 Active KR102513343B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662359419P 2016-07-07 2016-07-07
US62/359,419 2016-07-07
PCT/US2017/040809 WO2018009596A1 (en) 2016-07-07 2017-07-06 Phosphorus prodrugs of sgc stimulators

Publications (2)

Publication Number Publication Date
KR20190026841A KR20190026841A (ko) 2019-03-13
KR102513343B1 true KR102513343B1 (ko) 2023-03-22

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US (4) US10927136B2 (https=)
EP (1) EP3481837B1 (https=)
JP (2) JP7016853B2 (https=)
KR (1) KR102513343B1 (https=)
CN (2) CN109476686B (https=)
AU (2) AU2017291826B2 (https=)
BR (1) BR112019000290B1 (https=)
CA (1) CA3029374A1 (https=)
EA (1) EA039683B1 (https=)
IL (1) IL263993B2 (https=)
MA (1) MA45592A (https=)
MX (2) MX391896B (https=)
WO (1) WO2018009596A1 (https=)

Families Citing this family (5)

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Publication number Priority date Publication date Assignee Title
CN109476686B (zh) * 2016-07-07 2022-01-18 赛克里翁治疗有限公司 sGC刺激剂的磷前药
KR20210031931A (ko) 2018-07-11 2021-03-23 사이클리온 테라퓨틱스, 인크. 미토콘드리아 장애의 치료를 위한 sGC 자극제의 용도
CN114377149B (zh) * 2021-12-14 2023-11-10 西北工业大学 一种Mn基可降解MOF纳米反应器及其制备方法和应用
WO2024102304A1 (en) * 2022-11-07 2024-05-16 Virginia Commonwealth University Benzaldehyde compounds with direct polymer destabilizing effects to treat sickle cell disease
CN116478309B (zh) * 2023-05-19 2024-05-17 青海大学 锁阳精多糖、锁阳多糖化合物及制备方法和应用

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