KR102506839B1 - Gel-type cosmetic composition for spraying - Google Patents
Gel-type cosmetic composition for spraying Download PDFInfo
- Publication number
- KR102506839B1 KR102506839B1 KR1020220106945A KR20220106945A KR102506839B1 KR 102506839 B1 KR102506839 B1 KR 102506839B1 KR 1020220106945 A KR1020220106945 A KR 1020220106945A KR 20220106945 A KR20220106945 A KR 20220106945A KR 102506839 B1 KR102506839 B1 KR 102506839B1
- Authority
- KR
- South Korea
- Prior art keywords
- weight
- gellan gum
- extract
- calcium lactate
- hydrolyzed collagen
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 135
- 239000002537 cosmetic Substances 0.000 title claims abstract description 43
- 238000005507 spraying Methods 0.000 title claims abstract description 43
- 102000008186 Collagen Human genes 0.000 claims abstract description 93
- 108010035532 Collagen Proteins 0.000 claims abstract description 93
- 229920001436 collagen Polymers 0.000 claims abstract description 93
- 229920002148 Gellan gum Polymers 0.000 claims abstract description 90
- 239000000216 gellan gum Substances 0.000 claims abstract description 90
- 235000010492 gellan gum Nutrition 0.000 claims abstract description 90
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 claims abstract description 83
- 239000001527 calcium lactate Substances 0.000 claims abstract description 83
- 235000011086 calcium lactate Nutrition 0.000 claims abstract description 83
- 229960002401 calcium lactate Drugs 0.000 claims abstract description 83
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 51
- 230000003750 conditioning effect Effects 0.000 claims abstract description 40
- 239000004480 active ingredient Substances 0.000 claims abstract description 17
- RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 claims description 88
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 84
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 41
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- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 37
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- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 33
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
Description
본 발명은 분사용 젤타입 화장료 조성물에 관한 것으로, 더 자세하게는 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트를 유효성분으로 포함하여, 각종 분사용기에 용이하게 적용 가능한 분사용 제형을 형성할 수 있음은 물론, 피부에 유용한 피부컨디셔닝제의 활성성분을 촉진하여, 피부 관리 효과가 탁월한 분사용 젤타입 화장료 조성물에 관한 것이다. The present invention relates to a gel-type cosmetic composition for spraying, and more particularly, contains hydrolyzed collagen, gellan gum and calcium lactate as active ingredients, and can form a spraying formulation that can be easily applied to various spraying machines. It relates to a gel-type cosmetic composition for spraying, which, of course, promotes the active ingredient of a skin conditioning agent useful for the skin, and has excellent skin care effects.
리치하고 영양감있는 화장수를 선호하던 과거와 달리 현재 소비자들은 적당한 보습 및 영양감을 가지면서도 산뜻한 사용감과 편리한 사용법을 지닌 화장수에 대한 선호도가 높다. 이에 따라 미스트 타입 또는 에어로졸과 같이 간편하게 분사하여 사용하는 방식의 제품군이 증가하는 추세이다.Unlike in the past, when rich and nutritious lotions were preferred, consumers now have a high preference for lotions that have moderate moisturizing and nutritious sensations, as well as a refreshing feeling and convenient use. Accordingly, the trend is to increase the number of product groups that are easily sprayed and used, such as mist type or aerosol.
그러나, 분사용 타입은 내용물의 점도가 높을 경우 분사되는 분사각이 좁아져 사용이 용이하지 않기 때문에, 내용물이 일반적으로 점도가 거의 없는 액상 형태로만 제한되며 이에 따라 내용물이 피부에서 흘러내리는 현상이 발생하였다.However, since the injection type is not easy to use because the spray angle narrows when the viscosity of the content is high, the content is generally limited to a liquid form with little viscosity, and as a result, the content flows down the skin. did
이러한 문제점을 해결하기 위하여, 젤란검 등의 겔화제를 이용한 젤타입의 분사용 제품이 개발되었다. 젤란검(gellan gum)은 탄수화물에 미생물을 순수배양 및 발효시켜 얻은 고분자 다당류 물질을 이소프로필알콜로 정제하고 건조, 분쇄하여 얻어지는 헤테로폴리사카라이드(heteropolysaccharide)이다. 상기 헤테로폴리사카라이드는 람노오스, 글루쿠론산 및 포도당이 1:1:2로 구성되어 있으며, 상기 글루쿠론산은 칼륨, 나트륨, 칼슘, 마그네슘염 등을 혼합하여 중화한다. 젤란검은 회백색의 분말로서 탈 이온화된 뜨겁거나 차가운 물에 용해되고, 적은 양으로도 젤을 형성하며, 열, pH 등에 대한 안정성이 높고 투명하여 적용성이 좋다.In order to solve this problem, a gel-type injection product using a gelling agent such as gellan gum has been developed. Gellan gum is a heteropolysaccharide obtained by purifying, drying, and pulverizing a high-molecular polysaccharide material obtained by pure culture and fermentation of microorganisms on carbohydrates with isopropyl alcohol. The heteropolysaccharide is composed of rhamnose, glucuronic acid, and glucose in a ratio of 1:1:2, and the glucuronic acid is neutralized by mixing salts of potassium, sodium, calcium, magnesium, and the like. Gellan gum is an off-white powder that is soluble in deionized hot or cold water, forms a gel even in a small amount, has high stability against heat and pH, and is transparent, so it has good applicability.
젤란검을 고온에서 물에 분산, 수화시킨 후 별도의 물리적인 스트레스 없이 냉각하면 강한 겔(gel)이 형성되나, 냉각시에 전단력(shear)을 가할 경우 겔 내부의 결합이 약화된 약한 겔(gel)이 형성되고, 이 약한 겔(gel)은 외부에서 적은 힘만 가하여도 점도가 매우 낮아져서 액체와 같은 흐름성을 갖게 되는데 이러한 유동성 겔(fluide gel)은 점도를 거의 상승시키지 않으면서 분산 능력을 갖게 된다. 즉, 젤란검의 이러한 유동적인 특성을 적절히 조절하여 분사용 용기에서 분사되면서도 분사 시 젤 형태를 유지하여 흘러내림이 없는 분사용 화장료를 개발할 수 있다.When gellan gum is dispersed and hydrated in water at a high temperature and then cooled without any physical stress, a strong gel is formed. is formed, and this weak gel has a very low viscosity even when a small force is applied from the outside, so that it has flowability like a liquid. That is, it is possible to develop a cosmetic for spraying that does not run down by maintaining the gel form during spraying while being sprayed from a spray container by appropriately adjusting the fluidity of gellan gum.
이러한, 젤란검의 특성을 이용한 겔 타입 화장료로, 대한민국 등록특허공보 제10-2135047호(2020.07.17.)에는 "분사용 젤타입 화장료 조성물의 제조방법"이 게시된 바 있는데, 이는 (a) 가온한 정제수에 젤란검과 스클레로튬검 분말을 분산시키는 단계, (b) 단계 (a)의 생성물을 냉각하는 단계, (c) 단계 (b)의 생성물에 글리세린, 다이프로필렌글라이콜, 및 1,2-헥산다이올을 투입하는 단계, (d) 단계 (c)의 생성물을 여과하는 단계, (e) 정제수에 용해된 소듐시트레이트와 칼슘클로라이드를 단계 (d)의 생성물에 첨가하는 단계, 및 (f) 단계 (e)의 생성물을 냉각시켜 젤화하는 단계를 포함하는 것을 특징으로 하는 분사용 젤타입 화장료 조성물의 제조방법에 관한 것이다. As a gel-type cosmetic using the properties of gellan gum, Korean Patent Registration No. 10-2135047 (July 17, 2020) has published a "method for producing a gel-type cosmetic composition for spraying", which is (a) Dispersing gellan gum and sclerotium gum powder in warm purified water, (b) cooling the product of step (a), (c) glycerin, dipropylene glycol, and Injecting 1,2-hexanediol, (d) filtering the product of step (c), (e) adding sodium citrate and calcium chloride dissolved in purified water to the product of step (d) , And (f) relates to a method for producing a gel-type cosmetic composition for spraying, characterized in that it comprises the step of gelling the product of step (e) by cooling.
그러나 분사용 겔 타입의 화장료는 제형이 뭉글뭉글하여 분사시 성분들이 균일하게 분사되기 어려울 뿐만 아니라, 피부에 충분한 보습력을 유지하기는 한계가 있었으며, 오히려 분사된 화장료 성분들이 빠르게 증발하면서 피부가 더욱 건조해지는 느낌을 가지게 하였다. However, the gel-type cosmetics for spraying have a lumpy formulation, so it is difficult to spray the ingredients evenly when spraying, and there is a limit to maintaining sufficient moisturizing power on the skin. Rather, the sprayed cosmetic ingredients evaporate quickly, making the skin more dry It gave me a feeling of breaking up.
상기와 같은 문제점을 해결하기 위하여 본 발명은 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트를 유효성분으로 포함하여, 각종 분사용기에 용이하게 적용 가능한 분사용 제형을 형성할 수 있음은 물론, 피부에 유용한 피부컨디셔닝제의 활성성분을 촉진하여, 피부 관리 효과가 탁월한 분사용 젤타입 화장료 조성물을 제공하는데 목적이 있다. In order to solve the above problems, the present invention includes hydrolyzed collagen, gellan gum, and calcium lactate as active ingredients, and can form a spray formulation that can be easily applied to various spray devices, as well as skin An object of the present invention is to provide a spraying gel-type cosmetic composition with excellent skin care effects by promoting active ingredients of skin conditioning agents useful for skin care.
상기와 같은 문제점을 해결하기 위하여, 본 발명은 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트를 유효성분으로 포함하는 것을 특징으로 하는 분사용 젤타입 화장료 조성물을 제공한다. In order to solve the above problems, the present invention provides a gel-type cosmetic composition for spraying, characterized in that it contains hydrolyzed collagen, gellan gum and calcium lactate as active ingredients.
또한, 상기 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 외에, 사이아노코발아민을 유효성분으로 더 포함하는 것을 특징으로 한다. In addition, in addition to the hydrolyzed collagen, gellan gum and calcium lactate, it is characterized in that it further comprises cyanocobalamin as an active ingredient.
또한, 상기 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 외에, 자일리틸글루코사이드, 안하이드로자일리톨, 자일리톨, 글리세린, 글루코오스, 하이드록시프로필트라이모늄하이알루로네이트, 하이드롤라이즈드하이알루로닉애씨드, 소듐아세틸레이티드하이알루로네이트, 소듐하이알루로네이트크로스폴리머, 트레할로오스로 이루어지는 군에서 선택된 1종 이상의 보습제를 더 포함하는 것을 특징으로 한다. In addition, in addition to the hydrolyzed collagen, gellan gum and calcium lactate, xylityl glucoside, anhydroxylitol, xylitol, glycerin, glucose, hydroxypropyltrimonium hyaluronate, hydrolyzed hyaluronic acid , sodium acetylated hyaluronate, sodium hyaluronate crosspolymer, characterized in that it further comprises at least one moisturizer selected from the group consisting of trehalose.
또한, 상기 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트와 외에, 정제수, 1,2-헥산다이올, 다이프로필렌글라이콜, 프로판다이올, 부틸렌글라이콜로 이루어지는 군에서 선택된 1종 이상의 용제를 더 포함하는 것을 특징으로 한다. In addition, in addition to the hydrolyzed collagen, gellan gum and calcium lactate, at least one solvent selected from the group consisting of purified water, 1,2-hexanediol, dipropylene glycol, propanediol, and butylene glycol It is characterized in that it further comprises.
또한, 상기 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트와 외에, 닥풀뿌리추출물, 연꽃추출물, 개똥쑥추출물, 쌀추출물, 효모발효물, 두충나무껍질추출물, 병풀추출물, 아시아티코사이드, 마데카식애씨드, 아시아틱애씨드, 마데카소사이드 아데노신, 소듐하이알루로네이트, 나이아신아마이드, 수크로오스스테아레이트, 하이알루로닉애씨드, 하이드롤라이즈드소듐하이알루로네이트, 포타슘하이알루로네이트, 하이드로제네이티드포스파티딜콜린, 카프릴릭/카프릭트라이글리세라이드, 세테아릴알코올로 이루어지는 군에서 선택된 1종 이상의 피부컨디셔닝제를 더 포함하는 것을 특징으로 한다. In addition, in addition to the hydrolyzed collagen, gellan gum and calcium lactate, mulberry root extract, lotus extract, wormwood extract, rice extract, yeast fermented product, euworm bark extract, centella asiatica extract, asiaticoside, madecassic Acid, Asiatic Acid, Madecassoside Adenosine, Sodium Hyaluronate, Niacinamide, Sucrose Stearate, Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hydrogenated Phosphatidylcholine , caprylic / capric triglyceride, characterized in that it further comprises at least one skin conditioning agent selected from the group consisting of cetearyl alcohol.
본 발명에 따른 분사용 젤타입 화장료 조성물은 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트를 유효성분으로 포함하여, 각종 분사용기에 용이하게 적용 가능한 분사용 제형을 형성할 수 있음은 물론, 피부에 유용한 피부컨디셔닝제의 활성성분을 촉진하여, 피부 관리에 용이하다. The gel-type cosmetic composition for injection according to the present invention contains hydrolyzed collagen, gellan gum, and calcium lactate as active ingredients, and can form a formulation for injection that can be easily applied to various injection devices, as well as skin It promotes the active ingredients of skin conditioning agents useful for skin care and is easy to manage.
도 1은 실시예 1 내지 12, 비교예 1 내지 14, 제조예 1에서 제조한 조성물의 분사 실험에 관한 그래프.
도 2는 실시예 1 내지 12, 비교예 1 내지 14, 제조예 1에서 제조한 조성물의 제품 사용성 평가 실험에 관한 그래프.
도 3은 실시예 1 내지 12, 비교예 1 내지 14, 제조예 1에서 제조한 조성물의 피부 보습 효과 실험에 관한 그래프. 1 is a graph related to spraying experiments of the compositions prepared in Examples 1 to 12, Comparative Examples 1 to 14, and Preparation Example 1.
2 is a graph related to product usability evaluation experiments of the compositions prepared in Examples 1 to 12, Comparative Examples 1 to 14, and Preparation Example 1.
Figure 3 is a graph relating to the skin moisturizing effect test of the composition prepared in Examples 1 to 12, Comparative Examples 1 to 14, and Preparation Example 1.
이하의 본 발명에 관한 상세한 설명들은 본 발명이 실시될 수 있는 실시 예이고 해당 실시 예의 예시로써 도시된 첨부 도면을 참조한다. 이들 실시 예는 당 업자가 본 발명의 실시에 충분하도록 상세히 설명된다. 본 발명의 다양한 실시 예는 서로 다르지만 상호 배타적일 필요는 없음이 이해되어야 한다. 예를 들어, 여기에 기재되어 있는 특정 형상, 구조 및 특성은 일 실시 예에 관련하여 본 발명의 사상 및 범위를 벗어나지 않으면서 다른 실시 예로 구현될 수 있다. 또한, 각각의 기재된 실시예 내의 개별 구성요소의 위치 또는 배치는 본 발명의 사상 및 범위를 벗어나지 않으면서 변경될 수 있음이 이해되어야 한다. The detailed description of the present invention below refers to the accompanying drawings shown as examples of embodiments in which the present invention can be practiced. These embodiments are described in detail so that those skilled in the art will be able to practice the present invention. It should be understood that the various embodiments of the present invention are different, but need not be mutually exclusive. For example, specific shapes, structures, and characteristics described herein may be implemented in one embodiment in another embodiment without departing from the spirit and scope of the invention. Additionally, it should be understood that the location or arrangement of individual components within each described embodiment may be changed without departing from the spirit and scope of the invention.
따라서 후술되는 상세한 설명은 한정적인 의미로서 취하려는 것이 아니며, 본 발명의 범위는 적절하게 설명된다면 그 청구항들이 주장하는 것과 균등한 모든 범위와 더불어 첨부된 청구항에 의해서만 한정된다. 도면에서 유사한 참조부호는 여러 측면에 걸쳐서 동일하거나 유사한 기능을 지칭한다. Accordingly, the detailed description set forth below is not to be taken in a limiting sense, and the scope of the present invention, if properly described, is limited only by the appended claims, along with all equivalents as claimed by those claims. Like reference numbers in the drawings indicate the same or similar function throughout the various aspects.
본 발명에서 사용되는 용어는 본 발명에서의 기능을 고려하면서 가능한 현재 널리 사용되는 일반적인 용어들을 선택하였으나, 이는 당 분야에 종사하는 기술자의 의도 또는 판례, 새로운 기술의 출현 등에 따라 달라질 수 있다. 또한, 특정한 경우는 출원인이 임의로 선정한 용어도 있으며, 이 경우 해당되는 발명의 설명 부분에서 상세히 그 의미를 기재할 것이다. 따라서 본 발명에서 사용되는 용어는 단순한 용어의 명칭이 아닌, 그 용어가 가지는 의미와 본 발명의 전반에 걸친 내용을 토대로 정의되어야 한다. The terms used in the present invention have been selected from general terms that are currently widely used as much as possible while considering the functions in the present invention, but these may vary depending on the intention of a person skilled in the art or precedent, the emergence of new technologies, and the like. In addition, in a specific case, there is also a term arbitrarily selected by the applicant, and in this case, the meaning will be described in detail in the description of the invention. Therefore, the term used in the present invention should be defined based on the meaning of the term and the overall content of the present invention, not simply the name of the term.
본 발명에서 어떤 부분이 어떤 구성요소를 “포함”한다고 할 때, 이는 특별히 반대되는 기재가 없는 한, 다른 구성요소를 제외하는 것이 아니라 다른 구성요소를 더 포함할 수 있음을 의미한다. In the present invention, when a part "includes" a certain component, it means that it may further include other components, not excluding other components, unless otherwise stated.
이하, 본 발명에 따른 분사용 젤타입 화장료 조성물에 대하여 자세히 설명한다. Hereinafter, the gel-type cosmetic composition for spraying according to the present invention will be described in detail.
본 발명에 따른 분사용 젤타입 화장료 조성물은 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트를 유효성분으로 포함한다. The gel-type cosmetic composition for spraying according to the present invention contains hydrolyzed collagen, gellan gum and calcium lactate as active ingredients.
본 발명에 따른 분사용 젤타입 화장료 조성물은 상기 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트를 유효성분으로 포함함으로써, 각종 분사용기에 용이하게 적용 가능한 분사용 제형을 형성할 수 있음은 물론, 피부에 유용한 피부컨디셔닝제의 활성성분을 촉진하여, 피부 관리에 용이한 효과를 가질 수 있다. The gel-type cosmetic composition for injection according to the present invention contains the hydrolyzed collagen, gellan gum, and calcium lactate as active ingredients, thereby forming a formulation for injection that can be easily applied to various injection devices, By promoting the active ingredients of the skin conditioning agent useful for the skin, it can have an easy effect on skin care.
상기 하이드롤라이즈드콜라겐(Hydrolyzed Collagen)은 산, 효소 혹은 다른 방법으로 동물 또는 어류 콜라겐을 가수분해한 것으로써, 주로 헤어컨디셔닝제, 네일컨디셔닝제, 피부컨디셔닝제로 사용되는 성분이다. The hydrolyzed collagen (Hydrolyzed Collagen) is obtained by hydrolyzing animal or fish collagen with an acid, enzyme or other method, and is a component mainly used as a hair conditioning agent, nail conditioning agent, and skin conditioning agent.
상기 젤란검(Gellan Gum)은 탄수화물을 (Pseudomonas elodea)로 순수배양 발효하여 얻은 고분자량의 헤테로폴리사카라이드검을 지칭하며, 주로 유화안정제, 수용성점증제로 사용된다. The gellan gum refers to a high molecular weight heteropolysaccharide gum obtained by pure culture and fermentation of carbohydrates (Pseudomonas elodea), and is mainly used as an emulsion stabilizer and a water-soluble thickener.
상기 칼슘락테이트(Calcium Lactate)는 하기 화학식 1의 구조를 갖는 락틱애씨드의 칼슘염이다. 상기 칼슘락테이트의 시성식은 C3H6O3 ㆍ 1/2Ca 이며, 상기 칼슘락테이트는 주로 수렴제, 각질제거제로 사용된다. The calcium lactate (Calcium Lactate) is a calcium salt of lactic acid having a structure of Formula 1 below. The aging formula of the calcium lactate is C3H6O3 1/2Ca, and the calcium lactate is mainly used as an astringent and exfoliant.
한편, 본 발명에 따른 분사용 젤타입 화장료 조성물은 상기 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 외에, 사이아노코발아민을 유효성분으로 더 포함할 수 있다. 상기 사이아노코발아민은 하기 화학식 2의 구조를 갖는 유기화합물이다. 상기 사이아노코발아민의 시성식은 C63H88CoN14O14P 이며, 상기 사이아노코발아민은 주로 피부컨디셔닝제(기타)로 사용된다. 복합성, 비타민 B12 활성을 보이는 일군의 화합물을 총칭하며 8종류 B 군의 한 종류다. Meanwhile, the gel-type cosmetic composition for spraying according to the present invention may further contain cyanocobalamin as an active ingredient in addition to the hydrolyzed collagen, gellan gum and calcium lactate. The cyanocobalamin is an organic compound having a structure represented by Chemical Formula 2 below. The aging formula of the cyanocobalamin is C63H88CoN14O14P, and the cyanocobalamin is mainly used as a skin conditioning agent (other). It is a general term for a group of compounds showing complex and vitamin B12 activity, and is one of the eight B groups.
또한, 본 발명에 따른 분사용 젤타입 화장료 조성물은 상기 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 외에, 자일리틸글루코사이드, 안하이드로자일리톨, 자일리톨, 글리세린, 글루코오스, 하이드록시프로필트라이모늄하이알루로네이트, 하이드롤라이즈드하이알루로닉애씨드, 소듐아세틸레이티드하이알루로네이트, 소듐하이알루로네이트크로스폴리머, 트레할로오스로 이루어지는 군에서 선택된 1종 이상의 보습제를 더 포함할 수 있다. In addition, the gel-type cosmetic composition for spraying according to the present invention includes, in addition to the hydrolyzed collagen, gellan gum and calcium lactate, xylityl glucoside, anhydroxylitol, xylitol, glycerin, glucose, hydroxypropyltrimonium hyaluronan At least one moisturizer selected from the group consisting of nate, hydrolyzed hyaluronic acid, sodium acetylated hyaluronate, sodium hyaluronate crosspolymer, and trehalose may be further included.
상기 자일리틸글루코사이드(Xylitylglucoside)는 하기 화학식 3의 구조를 갖는 유기화합물이다. 상기 자일리틸글루코사이드는 주로 피부컨디셔닝제(보습제)로 사용된다. The xylitylglucoside is an organic compound having a structure represented by Chemical Formula 3 below. The xylityl glucoside is mainly used as a skin conditioning agent (moisturizer).
상기 안하이드로자일리톨(Anhydroxylitol)은 하기 화학식 4의 구조를 갖는 유기화합물이다. 상기 안하이드로자일리톨의 시성식은 C5H10O4이며, 상기 안하이드로자일리톨은 주로 피부컨디셔닝제(보습제)로 사용된다. Anhydroxylitol is an organic compound having a structure represented by Chemical Formula 4 below. The aging formula of the anhydroxylitol is C5H10O4, and the anhydroxylitol is mainly used as a skin conditioning agent (moisturizer).
상기 자일리톨(Xylitol)은 하기 화학식 5의 구조를 갖는 유기화합물이다. 상기 자일리톨의 시성식은 C5H12O5 이며, 상기 자일리톨은 주로 감미제, 보습제, 피부보습제로 사용된다. The xylitol is an organic compound having a structure represented by Chemical Formula 5 below. The acid formula of xylitol is C5H12O5, and xylitol is mainly used as a sweetener, moisturizer, and skin moisturizer.
상기 글리세린(Glycerin)은 하기 화학식 6의 구조를 갖는 유기화합물이다. 상기 글리세린의 시성식은 C3H8O3 이며, 상기 글리세린은 주로 변성제, 착향제, 헤어컨디셔닝제, 보습제, 피부보호제, 피부컨디셔닝제(보습제), 점도감소제 등으로 사용된다. The glycerin is an organic compound having a structure represented by Chemical Formula 6 below. The aging formula of the glycerin is C3H8O3, and the glycerin is mainly used as a denaturant, a flavoring agent, a hair conditioning agent, a moisturizer, a skin protecting agent, a skin conditioning agent (moisturizing agent), and a viscosity reducing agent.
상기 글루코오스(Glucose)는 녹말의 가수분해에 의해 얻은 당이다. 상기 글루코오스의 시성식은 C6H12O6 이며, 상기 글루코오스는 주로 감미제, 보습제, 피부컨디셔닝제(보습제), 피부컨디셔닝제(기타) 등으로 사용된다. The glucose (Glucose) is a sugar obtained by hydrolysis of starch. The acid formula of the glucose is C6H12O6, and the glucose is mainly used as a sweetener, a moisturizer, a skin conditioning agent (moisturizing agent), and a skin conditioning agent (others).
상기 하이드록시프로필트라이모늄하이알루로네이트(Hydroxypropyltrimonium Hyaluronate)는 하기 화학식 7의 구조를 갖는 4급 암모늄염이다. R은 히아루로닉애씨드이다. 상기 하이드록시프로필트라이모늄하이알루로네이트는 주로 피막형성제, 보습제로 사용된다. The hydroxypropyltrimonium hyaluronate (Hydroxypropyltrimonium Hyaluronate) is a quaternary ammonium salt having a structure of Formula 7 below. R is hyaluronic acid. The hydroxypropyltrimonium hyaluronate is mainly used as a film forming agent and a moisturizing agent.
상기 하이드롤라이즈드하이알루로닉애씨드(Hydrolyzed Hyaluronic Acid)는 산, 효소 또는 다른 방법으로 하이알루론산을 가수분해한 것이다. 상기 하이드롤라이즈드하이알루로닉애씨드는 주로 헤어컨디셔닝제, 피부컨디셔닝제(보습제)로 사용된다. The hydrolyzed hyaluronic acid is obtained by hydrolyzing hyaluronic acid with an acid, enzyme or other method. The hydrolyzed hyaluronic acid is mainly used as a hair conditioning agent and skin conditioning agent (moisturizer).
상기 소듐아세틸레이티드하이알루로네이트(Sodium Acetylated Hyaluronate)는 소듐하이알루로네이트의 아세틸에스터이다. 상기 소듐아세틸레이티드하이알루로네이트는 주로 보습제로 사용된다. The sodium acetylated hyaluronate is an acetyl ester of sodium hyaluronate. The sodium acetylated hyaluronate is mainly used as a moisturizing agent.
상기 소듐하이알루로네이트크로스폴리머(Sodium Hyaluronate Crosspolymer)는 비닐설폰과 가교된 하이알루로닉애씨드 중합체의 소듐염이다. 상기 소듐하이알루로네이트크로스폴리머는 주로 피부보습제, 피부컨디셔닝제로 사용된다. The sodium hyaluronate crosspolymer is a sodium salt of hyaluronic acid polymer crosslinked with vinylsulfone. The sodium hyaluronate crosspolymer is mainly used as a skin moisturizer and skin conditioning agent.
상기 트레할로오스(Trehalose)는 하기 화학식 8의 구조를 갖는 다이사카라이드이다. 상기 트레할로오스의 시성식은 C12H22O11 이며, 상기 트레할로오스는 주로 감미제, 보습제로 사용된다. The trehalose is a disaccharide having a structure represented by Chemical Formula 8 below. The acid formula of trehalose is C12H22O11, and trehalose is mainly used as a sweetening agent and a moisturizing agent.
또한, 본 발명에 따른 분사용 젤타입 화장료 조성물은 상기 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트와 외에, 정제수, 1,2-헥산다이올, 다이프로필렌글라이콜, 프로판다이올, 부틸렌글라이콜로 이루어지는 군에서 선택된 1종 이상의 용제를 더 포함할 수 있다. In addition, the gel-type cosmetic composition for injection according to the present invention, in addition to the hydrolyzed collagen, gellan gum and calcium lactate, purified water, 1,2-hexanediol, dipropylene glycol, propanediol, butyl One or more solvents selected from the group consisting of len glycol may be further included.
상기 정제수(Water)는 상수를 증류하거나 이온교환수지 등을 통하여 정제한 물을 지칭한다. The purified water (Water) refers to water purified through distillation of constant water or ion exchange resin.
상기 1,2-헥산다이올(1,2-Hexanediol)은 하기 화학식 9의 구조는 갖는 유기 화합물이다. The 1,2-hexanediol is an organic compound having a structure represented by Chemical Formula 9 below.
상기 1,2-헥산다이올의 시성식은 C6H14O2 이며, 상기 1,2-헥산다이올은 주로 용제로 사용된다. The acid formula of the 1,2-hexanediol is C6H14O2, and the 1,2-hexanediol is mainly used as a solvent.
상기 다이프로필렌글라이콜(Dipropylene Glycol)은 하기 화학식 10의 구조를 갖는 다이올의 혼합물이다. The dipropylene glycol (Dipropylene Glycol) is a mixture of diols having a structure of Formula 10 below.
상기 다이프로필렌글라이콜의 시성식은 C6H14O3 이며, 상기 다이프로필렌글라이콜은 주로 착향제, 용제, 점도감소제, 피부컨디셔닝제로 사용된다. The acid formula of the dipropylene glycol is C6H14O3, and the dipropylene glycol is mainly used as a flavoring agent, solvent, viscosity reducing agent, and skin conditioning agent.
상기 프로판다이올(Propanediol)은 하기 화학식 11의 구조를 갖는 유기화합물이다. The propanediol is an organic compound having a structure represented by Chemical Formula 11 below.
상기 프로판다이올의 시성식은 C3H8O2 이며, 상기 프로판다이올은 주로 용제, 점도감소제로 사용된다. The acid formula of the propanediol is C3H8O2, and the propanediol is mainly used as a solvent and viscosity reducing agent.
상기 부틸렌글라이콜(Butylene Glycol)은 하기 화학식 12의 구조를 갖는 지방족 디올이다. The butylene glycol (Butylene Glycol) is an aliphatic diol having a structure represented by Chemical Formula 12 below.
상기 부틸렌글라이콜의 시성식은 C4H10O2 이며, 상기 부틸렌글라이콜은 주로 착향제, 피부컨디셔닝제, 용제, 점도감소제로 사용된다. The aging formula of the butylene glycol is C4H10O2, and the butylene glycol is mainly used as a flavoring agent, skin conditioning agent, solvent, and viscosity reducing agent.
또한, 본 발명에 따른 분사용 젤타입 화장료 조성물은 상기 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트와 외에, 닥풀뿌리추출물, 연꽃추출물, 개똥쑥추출물, 쌀추출물, 효모발효물, 두충나무껍질추출물, 병풀추출물, 아시아티코사이드, 마데카식애씨드, 아시아틱애씨드, 마데카소사이드 아데노신, 소듐하이알루로네이트, 나이아신아마이드, 수크로오스스테아레이트, 하이알루로닉애씨드, 하이드롤라이즈드소듐하이알루로네이트, 포타슘하이알루로네이트, 하이드로제네이티드포스파티딜콜린, 카프릴릭/카프릭트라이글리세라이드, 세테아릴알코올로 이루어지는 군에서 선택된 1종 이상의 피부컨디셔닝제를 더 포함할 수 있다. In addition, the gel-type cosmetic composition for injection according to the present invention, in addition to the hydrolyzed collagen, gellan gum and calcium lactate, mulberry root extract, lotus extract, wormwood extract, rice extract, yeast fermented product, eucalyptus bark Extract, Centella Asiatica Extract, Asiaticoside, Madecassic Acid, Asiatic Acid, Madecassoside Adenosine, Sodium Hyaluronate, Niacinamide, Sucrose Stearate, Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate , Potassium hyaluronate, hydrogenated phosphatidylcholine, caprylic / capric triglyceride, may further include one or more skin conditioning agents selected from the group consisting of cetearyl alcohol.
상기 닥풀뿌리추출물(Abelmoschus Manihot Root Extract)은 닥풀 (Abelmoschus manihot)의 뿌리에서 추출한 추출물을 지칭한다. The mulberry root extract (Abelmoschus Manihot Root Extract) refers to an extract extracted from the root of mulberry grass (Abelmoschus manihot).
상기 연꽃추출물(Nelumbium Speciosum Flower Extract, Nelumbo Nucifera Flower Extract)은 연꽃(Nelumbium speciosum or Nelumbo nucifera)의 꽃에서 추출한 추출물을 지칭한다. The lotus extract (Nelumbium Speciosum Flower Extract, Nelumbo Nucifera Flower Extract) refers to an extract extracted from the flower of the lotus (Nelumbium speciosum or Nelumbo nucifera).
상기 개똥쑥추출물(Artemisia Annua Extract)은 개똥쑥(Artemisia annua)의 지상부에서 추출한 추출물을 지칭한다. The Artemisia Annua Extract refers to an extract extracted from the aerial part of Artemisia annua.
상기 쌀추출물(Oryza Sativa (Rice) Extract)은 쌀 (Oryza sativa)에서 추출한 추출물을 지칭한다. The rice extract (Oryza Sativa (Rice) Extract) refers to an extract extracted from rice (Oryza sativa).
상기 효모발효물(Saccharomyces Ferment)은 미생물 효모를 배양 발효시켜 얻은 생성물을 지칭한다. The yeast fermented product (Saccharomyces Ferment) refers to a product obtained by culturing and fermenting microbial yeast.
상기 두충나무껍질추출물(Eucommia Ulmoides Bark Extract)은 두충(Eucommia Ulmoides)의 나무껍질에서 추출한 추출물을 지칭한다. The Eucommia Ulmoides Bark Extract refers to an extract extracted from the bark of Eucommia Ulmoides.
상기 병풀추출물(Centella Asiatica Extract)은 병풀(Centella asiatica)의 전초에서 추출한 추출물을 지칭한다. The centella asiatica extract refers to an extract extracted from the outpost of centella asiatica.
상기 아시아티코사이드(Asiaticoside)는 하기 화학식 13의 구조를 갖는 유기화합물이다. 상기 아시아티코사이드는 주로 산화방지제, 피부컨디셔닝제로 사용된다. The Asiaticoside is an organic compound having a structure represented by Chemical Formula 13 below. The asiaticoside is mainly used as an antioxidant and skin conditioning agent.
상기 마데카식애씨드(Madecassic Acid)는 하기 화학식 14의 구조를 갖는 유기화합물이다. 상기 마데카식애씨드의 시성식은 C30H48O6 이며, 상기 마데카식애씨드는 주로 피부컨디셔닝제(기타)로 사용된다. The Madecassic Acid is an organic compound having a structure represented by Formula 14 below. The acid formula of the madecassic acid is C30H48O6, and the madecassic acid is mainly used as a skin conditioning agent (others).
상기 아시아틱애씨드(Asiatic Acid)는 하기 화학식 15의 구조를 갖는 유기화합물이다. 상기 아시아틱애씨드의 시성식은 C30H48O5 이며, 상기 아시아틱애씨드는 주로 피부컨디셔닝제로 사용된다. The Asian acid is an organic compound having a structure represented by Chemical Formula 15 below. The aging formula of the asiatic acid is C30H48O5, and the asiatic acid is mainly used as a skin conditioning agent.
상기 마데카소사이드(Madecassoside)는 하기 화학식 16의 구조를 갖는 유기화합물이다. 상기 마데카소사이드의 시성식은 C48H78O20 이며, 상기 마데카소사이드는 주로 산화방지제, 피부보호제, 피부컨디셔닝제(기타)로 사용된다. The madecassoside is an organic compound having a structure represented by Chemical Formula 16 below. The acid formula of the madecassoside is C48H78O20, and the madecassoside is mainly used as an antioxidant, skin protectant, and skin conditioning agent (others).
상기 아데노신(Adenosine)은 하기 화학식 17의 구조를 갖는 헤테로사이클릭 유기화합물이다. 상기 아데노신의 시성식은 C10H13N5O4 이며, 상기 아데노신은 주로 피부컨디셔닝제, 주름개선(기능성화장품)용으로 사용된다. Adenosine is a heterocyclic organic compound having a structure represented by Chemical Formula 17 below. The canonical formula of adenosine is C10H13N5O4, and adenosine is mainly used for skin conditioning agents and wrinkle improvement (functional cosmetics).
상기 소듐하이알루로네이트(Sodium Hyaluronate)는 하이알루로닉애씨드의 소듐염이다. 상기 소듐하이알루로네이트의 시성식은 C5H10NO4·Na 이며, 상기 소듐하이알루로네이트는 주로 피부컨디셔닝제로 사용된다. The sodium hyaluronate is a sodium salt of hyaluronic acid. The acidification formula of the sodium hyaluronate is C5H10NO4·Na, and the sodium hyaluronate is mainly used as a skin conditioning agent.
상기 나이아신아마이드(Niacinamide Mandelate)는 하기 화학식 18의 구조를 갖는 나이아신아마이드와 만델릭애씨드의 염이다. 상기 나이아신아마이드의 시성식은 C6H6N2O C8H8O3 이며, 상기 나이아신아마이드는 주로 피부컨디셔닝제(기타)로 사용된다. The niacinamide (Niacinamide Mandelate) is a salt of niacinamide and mandelic acid having a structure represented by Chemical Formula 18 below. The aging formula of the niacinamide is C6H6N2O C8H8O3, and the niacinamide is mainly used as a skin conditioning agent (other).
상기 수크로오스스테아레이트(Sucrose Stearate)는 스테아릭애씨드와 수크로오스의 모노에스터이다. 상기 수크로오스스테아레이트의 시성식은 C30H56O12 이며, 상기 수크로오스스테아레이트는 주로 피부컨디셔닝제(유연제), 계면활성제(유화제)로 사용된다. The sucrose stearate is a monoester of stearic acid and sucrose. The aging formula of the sucrose stearate is C30H56O12, and the sucrose stearate is mainly used as a skin conditioning agent (softener) and a surfactant (emulsifier).
상기 하이알루로닉애씨드(Hyaluronic Acid)는 N-아세틸-D-글루코사민과 글루쿠로닉애씨드의 결합으로 얻은 천연의 뮤코폴리사카라이드이다. 상기 하이알루로닉애씨드는 주로 피부컨디셔닝제(기타), 점도증가제(수성)로 사용된다. The hyaluronic acid is a natural mucopolysaccharide obtained by combining N-acetyl-D-glucosamine and glucuronic acid. The hyaluronic acid is mainly used as a skin conditioning agent (other) and a viscosity increasing agent (aqueous).
상기 하이드롤라이즈드소듐하이알루로네이트(Hydrolyzed Sodium Hyaluronate)는 소듐하이알루로네이트를 산, 효소 혹은 다른 가수분해 방법으로 처리하여 얻은 것이다. 상기 하이드롤라이즈드소듐하이알루로네이트는 주로 피부컨디셔닝제(기타)로 사용된다. The hydrolyzed sodium hyaluronate is obtained by treating sodium hyaluronate with an acid, enzyme or other hydrolysis method. The hydrolyzed sodium hyaluronate is mainly used as a skin conditioning agent (other).
상기 포타슘하이알루로네이트(Potassium Hyaluronate)는 하이알루로닉애씨드의 포타슘염이다. 상기 포타슘하이알루로네이트는 주로 피부컨디셔닝제(기타)로 사용된다. The potassium hyaluronate is a potassium salt of hyaluronic acid. The potassium hyaluronate is mainly used as a skin conditioning agent (other).
상기 하이드로제네이티드포스파티딜콜린(Hydrogenated Phosphatidylcholine)는 포스파티딜콜린을 수소첨가하여 얻은 것이다. 상기 하이드로제네이티드포스파티딜콜린는 주로 피부컨디셔닝제, 계면활성제-유화제로 사용된다. The hydrogenated phosphatidylcholine is obtained by hydrogenating phosphatidylcholine. The hydrogenated phosphatidylcholine is mainly used as a skin conditioning agent and a surfactant-emulsifying agent.
상기 카프릴릭/카프릭트라이글리세라이드(Caprylic/Capric Triglyceride)는 카프릴릭과 카프릭애씨드 및 글리세린의 혼합 트라이에스터이다. 상기 카프릴릭/카프릭트라이글리세라이드는 주로 착향제, 피부컨디셔닝제(수분차단제), 용제로 사용된다. The Caprylic/Capric Triglyceride is a mixed triester of caprylic with capric acid and glycerin. The caprylic/capric triglyceride is mainly used as a flavoring agent, skin conditioning agent (moisture blocking agent), and solvent.
상기 세테아릴알코올(Cetearyl Alcohol)은 세틸 및 스테아릴알코올로 구성된 지방알코올의 혼합물이다. 상기 세테아릴알코올의 시성식은 C18H38O ㆍ C16H34O이며, 상기 세테아릴알코올은 주로 유화안정제, 불투명화제, 계면활성제-거품형성제, 점증제-수용성, 점증제-비수용성로 사용된다. The Cetearyl Alcohol is a mixture of fatty alcohols composed of cetyl and stearyl alcohol. Cetearyl alcohol has a formula of C18H38O•C16H34O, and cetearyl alcohol is mainly used as an emulsion stabilizer, opacifier, surfactant-foam forming agent, thickener-water-soluble, and thickener-water-insoluble.
한편, 본 발명에 따른 분사용 젤타입 화장료 조성물은 기타첨가제로써, 계면활성제(가용화제), 킬레이트제, 향료 등을 더 포함할 수 있으며, 이때, 계면활성제는 폴리글리세릴-10라우레이트, 킬레이트제는 다이소듐이디티에이 등을 포함할 수 있다. On the other hand, the gel-type cosmetic composition for spraying according to the present invention may further include a surfactant (solubilizer), a chelating agent, a fragrance, etc. as other additives. At this time, the surfactant is polyglyceryl-10 laurate, chelate Agents may include disodium EDTA and the like.
상기 폴리글리세릴-10라우레이트(Polyglyceryl-10 Laurate)는 라우릭애씨드와 폴리글리세린-10의 에스터이다. 상기 폴리글리세릴-10라우레이트의 시성식은 C42H84O22 이며, 상기 폴리글리세릴-10라우레이트는 주로 피부컨디셔닝제, 계면활성제-유화제로 사용된다. The polyglyceryl-10 laurate is an ester of lauric acid and polyglycerin-10. The aging formula of the polyglyceryl-10 laurate is C42H84O22, and the polyglyceryl-10 laurate is mainly used as a skin conditioning agent and a surfactant-emulsifying agent.
상기 다이소듐이디티에이(Disodium EDTA)는 하기 화학식 19의 구조를 갖는 다이아민이다. 상기 다이소듐이디티에이의 시성식은 C10H16N2O8·2Na 이며, 상기 다이소듐이디티에이는 금속이온봉쇄제로 주로 사용된다. Disodium EDTA is a diamine having a structure represented by Chemical Formula 19 below. The aging formula of the disodium EDTA is C10H16N2O8·2Na, and the disodium EDTA is mainly used as a sequestering agent for metal ions.
상기 향료는 화장품의 향기를 가하기 위한 천연물질과 인공물질의 혼합체를 지칭하는 것으로, 다양한 제형에 사용되어, 향기를 부여하거나, 일부 성분 고유의 냄새를 없애고, 제품의 사용감을 향상시키기는 성분이다. 상기 향료의 종류로는 멘톨, 피넨, 보르네올, 시네올, 리모넨, 유게놀, 리모넨, 테르피넨, 티몰 등이 있으며, 상기 향료는 화장품에서 특정 향을 생성하거나 가리기 위해 첨가하는 물질 혹은 물질들의 조합을 포함하는 물질을 구별하기 위해, 사용하는 성분표시명으로 정의된다. The fragrance refers to a mixture of natural and artificial substances for adding fragrance to cosmetics, and is used in various formulations to impart fragrance, eliminate odors inherent in some components, and improve the feeling of use of products. Types of the fragrance include menthol, pinene, borneol, cineol, limonene, eugenol, limonene, terpinene, thymol, and the like, and the fragrance is a substance or a combination of substances added to create or mask a specific fragrance in cosmetics In order to distinguish substances containing, it is defined as the ingredient display name used.
한편, 본 발명에 따른 분사용 젤타입 화장료 조성물에 있어서, 상기 젤란검은 0.0000000001 ~ 1.0중량%, 상기 칼슘락테이트는 0.0000000001 ~ 1.0중량%, 하이드롤라이즈드콜라겐은 잔량으로 포함될 수 있다. 보다 구체적으로, 본 발명에 따른 분사용 젤타입 화장료 조성물은 젤란검 0.13중량%, 칼슘락테이트 0.13중량%, 하이드롤라이즈드콜라겐은 잔량으로 포함될 수 있다.On the other hand, in the gel-type cosmetic composition for spraying according to the present invention, the gellan gum is 0.0000000001 to 1.0% by weight, the calcium lactate is 0.0000000001 to 1.0% by weight, and hydrolyzed collagen may be included in the remaining amount. More specifically, the gel-type cosmetic composition for spraying according to the present invention may include 0.13% by weight of gellan gum, 0.13% by weight of calcium lactate, and hydrolyzed collagen in the remaining amount.
본 발명에 따른 분사용 젤타입 화장료 조성물이 사이아노코발아민을 포함하는 경우, 젤란검 0.0000000001 ~ 1.0중량%, 칼슘락테이트 0.0000000001 ~ 1.0중량%, 사이아노코발아민 0.0000000001 ~ 1.0중량%, 하이드롤라이즈드콜라겐은 잔량으로 포함될 수 있다. 보다 구체적으로, 본 발명에 따른 분사용 젤타입 화장료 조성물이 사이아노코발아민을 포함하는 경우, 젤란검 0.13중량%, 칼슘락테이트 0.13중량%, 사이아노코발아민 0.001중량%, 하이드롤라이즈드콜라겐은 잔량으로 포함될 수 있다. When the gel-type cosmetic composition for spraying according to the present invention contains cyanocobalamin, 0.0000000001 to 1.0% by weight of gellan gum, 0.0000000001 to 1.0% by weight of calcium lactate, 0.0000000001 to 1.0% by weight of cyanocobalamin, hydrolyzed Decollagen may be included in a residual amount. More specifically, when the gel-type cosmetic composition for spraying according to the present invention contains cyanocobalamin, 0.13% by weight of gellan gum, 0.13% by weight of calcium lactate, 0.001% by weight of cyanocobalamin, hydrolyzed collagen may be included as a residual amount.
구체적인 실시예에서, 본 발명에 따른 분사용 젤타입 화장료 조성물은, 글리세린 0.0000000001 ~ 20.0중량%, 1,2-헥산다이올 0.0000000001 ~ 5.0중량%, 다이프로필렌글라이콜 0.0000000001 ~ 5.0중량%, 나이아신아마이드 0.0000000001 ~ 5.0중량%, 정제수 0.0000000001 ~ 5.0중량%, 트레할로오스 0.0000000001 ~ 5.0중량%, 부틸렌글라이콜 0.0000000001 ~ 1.0중량%, 닥풀뿌리추출물 0.0000000001 ~ 1.0중량%, 프로판다이올 0.0000000001 ~ 1.0중량%, 폴리글리세릴-10라우레이트 0.0000000001 ~ 1.0중량%, 젤란검 0.0000000001 ~ 1.0중량%, 칼슘락테이트 0.0000000001 ~ 1.0중량%, 아데노신 0.0000000001 ~ 1.0중량%, 향료 0.0000000001 ~ 1.0중량%, 하이드로제네이티드포스피딜콜린 0.0000000001 ~ 1.0중량%, 카프릴릭/카프릭트라이글리세라이드 0.0000000001 ~ 1.0중량%, 다이소듐이디티에이 0.0000000001 ~ 1.0중량%, 자일리틸글루코사이드 0.0000000001 ~ 1.0중량%, 병풀추출물 0.0000000001 ~ 1.0중량%, 수크로오스스테아레이트 0.0000000001 ~ 1.0중량%, 안하이드로자일리톨 0.0000000001 ~ 1.0중량%, 세테아릴알코올 0.0000000001 ~ 1.0중량%, 자일리톨 0.0000000001 ~ 1.0중량%, 두충나무껍질추출물 0.0000000001 ~ 1.0중량%, 글루코오스 0.0000000001 ~ 1.0중량%, 사이아노코발아민 0.0000000001 ~ 1.0중량%, 소듐하이알루로네이트 0.0000000001 ~ 1.0중량%, 아시아틱코사이드 0.0000000001 ~ 1.0중량%, 마데카식애씨드 0.0000000001 ~ 1.0중량%, 아시아틱애씨드 0.0000000001 ~ 1.0중량%, 마데카소사이드 0.0000000001 ~ 1.0중량%, 연꽃추출물 0.0000000001 ~ 1.0중량%, 개똥쑥추출물 0.0000000001 ~ 1.0중량%, 쌀추출물 0.0000000001 ~ 1.0중량%, 효모발효물 0.0000000001 ~ 1.0중량%, 하이드록시프로필트라이모늄하이알루로네이트 0.0000000001 ~ 1.0중량%, 하이드롤라이즈드하이알루로닉애씨드 0.0000000001 ~ 1.0중량%, 소듐아세틸레이티드하이알루로네이트 0.0000000001 ~ 1.0중량%, 하이알루로닉애씨드 0.0000000001 ~ 1.0중량%, 소듐하이알루로네이트크로스폴리머 0.0000000001 ~ 1.0중량%, 하이드롤라이즈드소듐하이알루로네이트 0.0000000001 ~ 1.0중량%, 포타슘하이알루로네이트 0.0000000001 ~ 1.0중량%로 포함하며, 잔량으로 하이드롤라이즈드콜라겐을 포함할 수 있다. In a specific embodiment, the gel-type cosmetic composition for spraying according to the present invention contains 0.0000000001 to 20.0% by weight of glycerin, 0.0000000001 to 5.0% by weight of 1,2-hexanediol, 0.0000000001 to 5.0% by weight of dipropylene glycol, and niacinamide. 0.0000000001 ~ 5.0%by weight, purified number 0.0000000001 ~ 5.0%by weight, Trehalose 0.0000000001 ~ 5.0%by weight, butylene glycol 0.00000001 ~ 1.0 weight% , Polyglyceryl-10 Laurate 0.0000000001 ~ 1.0% by weight, Gellan Gum 0.0000000001 ~ 1.0% by weight, Calcium Lactate 0.0000000001 ~ 1.0% by weight, Adenosine 0.0000000001 ~ 1.0% by weight, Fragrance 0.00000000001 ~ 1.0% by weight Choline 0.0000000001 ~ 1.0 wt%, caprylic/capric triglyceride 0.0000000001 ~ 1.0 wt%, disodium EDTA 0.0000000001 ~ 1.0 wt%, xylityl glucoside 0.0000000001 ~ 1.0 wt%, centella extract 0.0001000 10 wt% Sucroos stearate 0.0000000001 ~ 1.0%by weight, 0.0000000001 ~ 1.0%by weight of Anhid Rossilitol, 0.000000000001 ~ 1.0 weight%, xylitol 0.0000000001 ~ 1.0 weight% %, cyanocobalamin 0.0000000001 to 1.0 wt%, sodium hyaluronate 0.0000000001 to 1.0 wt%, asiaticcoside 0.0000000001 to 1.0 wt%, madecassic acid 0.0000000001 to 1.0 wt%, asiatic acid 0.00000010
가장 구체적인 실시예에서, 글리세린은 8.31중량%, 1,2-헥산다이올은 3.66659중량%, 다이프로필렌글라이콜은 2.5중량%, 나이아신아마이드는 2.0중량%, 정제수는 1.252958753 중량%, 트레할로오스는 1.0중량%, 부틸렌글라이콜은 0.2335중량%, 닥풀뿌리추출물은 0.15중량%, 프로판다이올은 0.15중량%, 폴리글리세릴-10라우레이트는 0.15중량%, 젤란검은 0.13중량%, 칼슘락테이트는 0.13중량%, 아데노신은 0.04중량%, 향료는 0.03중량%, 하이드로제네이티드포스파티딜콜린은 0.02중량%, 카프릴릭/카프릭트라이글리세라이드는 0.02중량%, 다이소듐이디티에이는 0.02중량%, 자일리틸글루코사이드는 0.012중량%, 병풀추출물은 0.01중량%, 수크로오스스테아레이트는 0.01중량%, 안하이드로자일리톨은 0.0084중량%, 세테아릴알코올은 0.005중량%, 자일리톨은 0.0036중량%, 두충나무껍질추출물은 0.0025중량%, 글루코오스는 0.0012중량%, 사이아노코발아민은 0.001중량%, 소듐하이알루로네이트는 0.00011중량%, 아시아티코사이드는 0.0001중량%, 마데카식애씨드는 0.0001중량%, 아시아틱애씨드는 0.0001중량%, 마데카소사이드는 0.0001중량%, 연꽃추출물은 0.000075중량%, 개똥쑥추출물은 0.000075중량%, 쌀추출물은 0.000075중량%, 효모발효물은 0.000075중량%, 하이드록시프로필트라이모늄하이알루로네이트는 0.000001중량%, 하이드롤라이즈드하이알루로닉애씨드는 0.0000001중량%, 소듐아세틸레이티드하이알루로네이트는 0.0000001중량%, 하이알루로닉애씨드는 0.000000025중량%, 소듐하이알루로네이트크로스폴리머는 0.00000001중량%, 하이드롤라이즈드소듐하이알루로네이트는 0.00000001중량%, 포타슘하이알루로네이트는 0.000000002중량%로 포함되며, 하이드롤라이즈드콜라겐은 잔량인 80.14244중량%로 포함되는 것이 적절할 것이다. In a most specific embodiment, glycerin is 8.31%, 1,2-hexanediol is 3.66659%, dipropylene glycol is 2.5%, niacinamide is 2.0%, purified water is 1.252958753%, trehalo Oxide was 1.0% by weight, butylene glycol was 0.2335% by weight, mulberry root extract was 0.15% by weight, propanediol was 0.15% by weight, polyglyceryl-10 laurate was 0.15% by weight, gellan gum was 0.13% by weight, calcium Lactate was 0.13 wt%, adenosine was 0.04 wt%, fragrance was 0.03 wt%, hydrogenated phosphatidylcholine was 0.02 wt%, caprylic/capric triglyceride was 0.02 wt%, and disodium EDTA was 0.02 wt%. %, xylitylglucoside 0.012% by weight, centella asiatica extract 0.01% by weight, sucrose stearate 0.01% by weight, anhydroxylitol 0.0084% by weight, cetearyl alcohol 0.005% by weight, xylitol 0.0036% by weight Peel extract 0.0025% by weight, glucose 0.0012% by weight, cyanocobalamin 0.001% by weight, sodium hyaluronate 0.00011% by weight, asiaticoside 0.0001% by weight, madecassic acid 0.0001% by weight, asiatic Acid is 0.0001% by weight, madecassoside is 0.0001% by weight, lotus extract is 0.000075% by weight, wormwood extract is 0.000075% by weight, rice extract is 0.000075% by weight, yeast fermentation is 0.000075% by weight, hydroxypropyltrimonium high 0.000001% by weight of alluronate, 0.0000001% by weight of hydrolyzed hyaluronic acid, 0.0000001% by weight of sodium acetylated hyaluronate, 0.000000025% by weight of hyaluronic acid, sodium hyaluronate 0.00000001% by weight of crosspolymer, 0.00000001% by weight of hydrolyzed sodium hyaluronate, 0.000000002% by weight of potassium hyaluronate, and 80.14244% by weight of hydrolyzed collagen is appropriate. will be.
본 발명에 따른 화장료 조성물은 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트를 필수적으로 포함하는 조성물에 관한 것으로, 상기한 보습제, 용제, 피부컨디셔닝제, 기타첨가제 등은 임의에 의한 추가일 뿐, 이들이 꼭 포함되어야 하는 것은 아니다. The cosmetic composition according to the present invention relates to a composition essentially containing hydrolyzed collagen, gellan gum, and calcium lactate, and the above-described moisturizer, solvent, skin conditioning agent, and other additives are optional additions, They do not have to be included.
하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트의 조합, 내지는, 하이드롤라이즈드콜라겐, 젤란검, 칼슘락테이트 및 사이아노코발아민의 조합을 충족하는 한에서, 임의의 추가성분이 더 추가될 수 있는 것이며, 상세한 설명에 기재한 보습제, 용제, 피부컨디셔닝제, 기타첨가제 성분들이 본 발명의 권리 범위를 한정하지 않는다. 본 발명의 권리 범위는 청구항에 정한 범위로 정해질 것이다. Any additional ingredients may be further added as long as the combination of hydrolyzed collagen, gellan gum and calcium lactate, or the combination of hydrolyzed collagen, gellan gum, calcium lactate and cyanocobalamin is satisfied. It can be, and the moisturizing agent, solvent, skin conditioning agent, and other additive components described in the detailed description do not limit the scope of the present invention. The scope of the rights of the present invention will be defined as the scope set forth in the claims.
이하, 본 발명에 따른 분사용 젤타입 화장료 조성물의 제조방법에 대하여 간략히 설명한다. Hereinafter, a method for preparing a gel-type cosmetic composition for spraying according to the present invention will be briefly described.
본 발명에 따른 분사용 젤타입 화장료 조성물의 제조방법은, 메인 탱크에 하이드롤라이즈드콜라겐 및 젤란검을 투입하고 Paddle Mixer 5 ~ 20rpm 및 Homo Mix 500 ~ 2000 rpm 조건에서 70 ~ 90℃로 10 ~ 30분간 가열 혼합하는 제1 혼합단계(S10); 상기 제1 혼합단계(S10)의 혼합물에 다이소듐이디티에이, 트레할로오스. 나이아신아마이드, 아데노신, 1,2-헥산다이올, 글리세린으로 이루어진 군에서 선택된 어느 하나 이상의 성분을 추가하여 Paddle Mixer 5 ~ 20rpm 및 Homo Mix 500 ~ 2000 rpm 조건에서 70 ~ 90℃로 10 ~ 30분간 가열 혼합하는 제2 혼합단계(S20); 상기 제2 혼합단계(S20)의 혼합물에 하이드롤라이즈드콜라겐 및 칼슘락테이트를 70℃에서 용해하여 혼합하는 제3혼합단계(S30); 상기 제3혼합단계(S30)의 혼합물을 50 ~ 60℃ 까지 냉각하는 냉각단계(S40); 상기 냉각단계(S40)의 냉각된 혼합물에 다이프로필렌글라이콜, 프로판다이올, 폴리글리세릴-10라우레이트, 향료로 이루어진 군에서 선택된 어느 하나 이상의 성분을 추가하여 Paddle Mixer 5 ~ 20rpm 및 Homo Mix 500 ~ 2000 rpm 조건에서 50 ~ 60℃로 10 ~ 30분간 혼합하는 제4혼합단계(S50); 상기 제4혼합단계(S50)의 혼합물에 하이드로제네이티드포스파티딜콜린, 카프릴릭/카프릭트라이글리세라이드, 병풀추출물, 수크로오스스테아레이트, 세테아릴알코올, 아시아티코사이드, 마데카식애씨드, 아시아틱애씨드, 마데카소사이드, 부틸렌글라이콜, 두충나무껍질추출물, 닥풀뿌리추출물, 자일리틸글루코사이드, 안하이드로자일리톨, 자일리톨, 글루코오스, 연꽃추출물, 개똥쑥추출물, 쌀추출물, 효모발효물, 소듐하이알루로네이트, 소듐하이알루로네이트, 하이드롤라이즈드하이알루로닉애씨드, 소듐아세틸레이티드하이알루로네이트, 하이드록시프로필트라이모늄하이알루로네이트, 하이알루로닉애씨드, 소듐하이알루로네이트크로스폴리머, 포타슘하이알루로네이트, 하이드롤라이즈드소듐하이알루로네이트로 이루어진 군에서 선택된 어느 하나 이상의 성분을 추가하여 Paddle Mixer 5 ~ 20rpm 및 Homo Mix 500 ~ 2000 rpm 조건에서 50 ~ 60℃로 10 ~ 30분간 혼합하는 제5 혼합단계(S60); 상기 제5 혼합단계(S60)의 혼합물에 하이드롤라이즈드콜라겐 및 사이아노코발아민으로 이루어진 군에서 선택된 어느 하나 이상의 성분을 추가하여 Paddle Mixer 5 ~ 20rpm 및 Homo Mix 500 ~ 2000 rpm 조건에서 50 ~ 60℃로 10 ~ 30분간 혼합하는 제6 혼합단계(S70); 및, 상기 제6 혼합단계(S70)의 혼합물을 40 ~ 50℃까지 냉각하고 패키징하는 제품제조 단계(S80)를 포함할 수 있다. In the manufacturing method of the gel-type cosmetic composition for spraying according to the present invention, hydrolyzed collagen and gellan gum are added to the main tank, and the Paddle Mixer 5 ~ 20rpm and Homo Mix 500 ~ 2000 rpm conditions 10 ~ 30 at 70 ~ 90 ℃ A first mixing step (S10) of heating and mixing for minutes; Disodium EDTA and trehalose were added to the mixture in the first mixing step (S10). Add at least one component selected from the group consisting of niacinamide, adenosine, 1,2-hexanediol, and glycerin and heat at 70 to 90°C for 10 to 30 minutes at Paddle Mixer 5 to 20 rpm and Homo Mix 500 to 2000 rpm. A second mixing step of mixing (S20); A third mixing step (S30) of dissolving and mixing hydrolyzed collagen and calcium lactate in the mixture of the second mixing step (S20) at 70 ° C; A cooling step (S40) of cooling the mixture of the third mixing step (S30) to 50 to 60°C; To the cooled mixture of the cooling step (S40), at least one component selected from the group consisting of dipropylene glycol, propanediol, polyglyceryl-10 laurate, and fragrance is added to the Paddle Mixer 5 ~ 20 rpm and Homo Mix A fourth mixing step (S50) of mixing for 10 to 30 minutes at 50 to 60 ° C. at 500 to 2000 rpm; In the mixture of the fourth mixing step (S50), hydrogenated phosphatidylcholine, caprylic/capric triglyceride, centella asiatica extract, sucrose stearate, cetearyl alcohol, asiaticoside, madecassic acid, asiatic acid, Madecassoside, Butylene Glycol, Eucalyptus Bark Extract, Mulberry Root Extract, Xylityl Glucoside, Anhydroxylitol, Xylitol, Glucose, Lotus Extract, Artemisia Extract, Rice Extract, Yeast Fermented Product, Sodium Hyaluronate, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Potassium Add any one or more components selected from the group consisting of hyaluronate and hydrolyzed sodium hyaluronate and mix for 10 to 30 minutes at 50 to 60°C under Paddle Mixer 5 to 20 rpm and Homo Mix 500 to 2000 rpm conditions. A fifth mixing step (S60) to; To the mixture of the fifth mixing step (S60), at least one component selected from the group consisting of hydrolyzed collagen and cyanocobalamin is added to Paddle Mixer 5 ~ 20 rpm and Homo Mix 500 ~ 2000 rpm 50 ~ 60 A sixth mixing step (S70) of mixing for 10 to 30 minutes at ℃; And, it may include a product manufacturing step (S80) of cooling the mixture of the sixth mixing step (S70) to 40 ~ 50 ℃ and packaging.
이는 본 발명에 따른 분사용 젤타입 화장료 조성물을 제조하기 위한 수 많은 제조방법 중 일 예시일 뿐, 본 발명에 따른 분사용 젤타입 화장료 조성물이 상기한 제조방법 만으로 국한 되는 것은 아니다. This is only one example of a number of manufacturing methods for preparing the gel-type cosmetic composition for spraying according to the present invention, and the gel-type cosmetic composition for spraying according to the present invention is not limited to the above-described manufacturing method.
이하, 하기 실시예, 비교예, 제조예 및 실험예를 통하여 본 발명에 따른 분사용 젤타입 화장료 조성물이 갖는 효과에 대하여 자세히 설명한다. Hereinafter, the effect of the gel-type cosmetic composition for spraying according to the present invention will be described in detail through the following Examples, Comparative Examples, Preparation Examples and Experimental Examples.
실시예Example 1. One. 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum 및 and 칼슘락테이트를calcium lactate 포함하는 실험용 조성물의 제조 Preparation of an experimental composition comprising
하기 표 1의 조성으로 실시예 1의 조성물을 제조하였다. The composition of Example 1 was prepared with the composition shown in Table 1 below.
실시예Example 2. 2. 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate 및 and 사이아노코발아민을Cyanocobalamin 포함하는 실험용 조성물의 제조 Preparation of an experimental composition comprising
하기 표 2의 조성으로 실시예 2의 조성물을 제조하였다. The composition of Example 2 was prepared with the composition shown in Table 2 below.
비교예comparative example 1. One. 하이드롤라이즈드콜라겐hydrolyzed collagen 및 and 젤란검을gellan gum 포함하고, include, 칼슘락테이트는Calcium lactate is 포함하지 않은 실험용 조성물의 제조 Preparation of an experimental composition that does not contain
하기 표 3의 조성으로 비교예 1의 조성물을 제조하였다. The composition of Comparative Example 1 was prepared with the composition shown in Table 3 below.
비교예comparative example 2. 2. 하이드롤라이즈드콜라겐hydrolyzed collagen 및 and 칼슘락테이트를calcium lactate 포함하고, include, 젤란검은gellan gum 포함하지 않은 실험용 조성물의 제조 Preparation of an experimental composition that does not contain
하기 표 4의 조성으로 비교예 2의 조성물을 제조하였다.The composition of Comparative Example 2 was prepared with the composition shown in Table 4 below.
비교예comparative example 3. 3. 젤란검gellan gum 및 and 칼슘락테이트를calcium lactate 포함하고, include, 하이드롤라이즈드콜라겐은Hydrolyzed Collagen is 포함하지 않은 실험용 조성물의 제조 Preparation of an experimental composition that does not contain
하기 표 5의 조성으로 비교예 3의 조성물을 제조하였다. The composition of Comparative Example 3 was prepared with the composition shown in Table 5 below.
실시예Example 3. 3. 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아cyanococfolia 민을 포함하며, 글리세린을 더 포함하는 실험용 조성물의 제조Preparation of Experimental Composition Containing Min and Further Containing Glycerin
하기 표 6의 조성으로 실시예 3의 조성물을 제조하였다. The composition of Example 3 was prepared with the composition shown in Table 6 below.
실시예Example 4. 4. 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아cyanococfolia 민을 포함하며, 글리세린, 1,2-헥산다이올을 더 포함하는 실험용 조성물의 제조Preparation of Experimental Composition Containing Min and Further Containing Glycerin and 1,2-Hexanediol
하기 표 7의 조성으로 실시예 4의 조성물을 제조하였다. The composition of Example 4 was prepared with the composition shown in Table 7 below.
실시예Example 5. 5. 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아cyanoco germination 민을 포함하며, 글리세린, 1,2-Contains min, glycerin, 1,2- 헥산다이올Hexanediol , , 다이프로필렌글라이콜을dipropylene glycol 더 포함하는 실험용 조성물의 제조 Preparation of an experimental composition further comprising
하기 표 8의 조성으로 실시예 5의 조성물을 제조하였다. The composition of Example 5 was prepared with the composition shown in Table 8 below.
실시예Example 6. 6. 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아cyanococfolia 민을 포함하며, 글리세린, 1,2-Contains min, glycerin, 1,2- 헥산다이올Hexanediol , , 다이프로필렌글라이콜Dipropylene Glycol , , 나이아신아마이Niacinama 드를 더 포함하는 실험용 조성물의 제조Preparation of an experimental composition further comprising
하기 표 9의 조성으로 실시예 6의 조성물을 제조하였다. The composition of Example 6 was prepared with the composition shown in Table 9 below.
실시예Example 7. 하이드롤라이즈드콜라겐, 젤란검, 칼슘락테이트, 사이아노코발아민을 포함하며, 글리세린, 1,2- 7. Contains hydrolyzed collagen, gellan gum, calcium lactate, cyanocobalamin, glycerin, 1,2- 헥산다이올Hexanediol , , 다이프로필렌글라이콜Dipropylene Glycol , , 나이아신아마이Niacinama 드, 정제수를 더 포함하는 실험용 조성물의 제조De, Preparation of Experimental Composition Further Containing Purified Water
하기 표 10의 조성으로 실시예 7의 조성물을 제조하였다. The composition of Example 7 was prepared with the composition shown in Table 10 below.
실시예Example 8. 8. 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아cyanococfolia 민을 포함하며, contains Min, 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아민을Cyanocobalamin 포함하며, 글리세린, 1,2- Contains, glycerin, 1,2- 헥산다이올Hexanediol , , 다이프로필렌글라이콜Dipropylene Glycol , , 나이아신아마이Niacinama 드, 정제수, 트레할로오스를 더 포함하는 실험용 조성물의 제조Preparation of Experimental Composition Further Containing Hydrogen, Purified Water, and Trehalose
하기 표 11의 조성으로 실시예 8의 조성물을 제조하였다. The composition of Example 8 was prepared with the composition shown in Table 11 below.
실시예Example 9. 9. 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아민을Cyanocobalamin 포함하며, contains, 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아민을Cyanocobalamin 포함하며, 글리세린, 1,2- Contains, glycerin, 1,2- 헥산다이올Hexanediol , , 다이프로필렌글라이콜Dipropylene Glycol , , 나이아신아마이Niacinama 드, 정제수, 트레할로오스, 부틸렌글라이콜을 더 포함하는 실험용 조성물의 제조Preparation of Experimental Composition Further Containing Hydrogen, Purified Water, Trehalose, and Butylene Glycol
하기 표 12의 조성으로 실시예 9의 조성물을 제조하였다. The composition of Example 9 was prepared with the composition shown in Table 12 below.
실시예Example 10. 10. 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아민을Cyanocobalamin 포함하며, contains, 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아민을Cyanocobalamin 포함하며, 글리세린, 1,2- Contains, glycerin, 1,2- 헥산다이올Hexanediol , , 다이프로필렌글라이콜Dipropylene Glycol , , 나이아신아마이Niacinama 드, de, 정제수Purified water , , 트레할로오스trehalose , , 부틸렌글라이콜Butylene Glycol , , 닥풀뿌리추출물을mulberry root extract 더 포함하는 실험용 조성물의 제조 Preparation of an experimental composition further comprising
하기 표 13의 조성으로 실시예 10의 조성물을 제조하였다. The composition of Example 10 was prepared with the composition shown in Table 13 below.
실시예Example 11. 11. 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아민을Cyanocobalamin 포함하며, contains, 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아민을Cyanocobalamin 포함하며, 글리세린, 1,2- Contains, glycerin, 1,2- 헥산다이올Hexanediol , , 다이프로필렌글라이콜Dipropylene Glycol , , 나이아신아마이Niacinama 드, de, 정제수Purified water , , 트레할로오스trehalose , , 부틸렌글라이콜Butylene Glycol , , 닥풀뿌리추출물Mulberry Root Extract , , 프로판다이올을propanediol 더 포함하는 실험용 조성물의 제조 Preparation of an experimental composition further comprising
하기 표 14의 조성으로 실시예 11의 조성물을 제조하였다. The composition of Example 11 was prepared with the composition shown in Table 14 below.
실시예Example 12. 12. 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아민을Cyanocobalamin 포함하며, contains, 하이드롤라이즈드콜라겐hydrolyzed collagen , , 젤란검gellan gum , , 칼슘락테이트calcium lactate , , 사이아노코발아민을Cyanocobalamin 포함하며, 글리세린, 1,2- Contains, glycerin, 1,2- 헥산다이올Hexanediol , , 다이프로필렌글라이콜Dipropylene Glycol , , 나이아신아마이Niacinama 드, de, 정제수Purified water , , 트레할로오스trehalose , , 부틸렌글라이콜Butylene Glycol , , 닥풀뿌리추출물Mulberry Root Extract , , 프로판다이올propanediol , , 폴리Poly 글리세릴-10라우레이트를 더 포함하는 실험용 조성물의 제조Preparation of an experimental composition further comprising glyceryl-10 laurate
하기 표 15의 조성으로 실시예 12의 조성물을 제조하였다. The composition of Example 12 was prepared with the composition shown in Table 15 below.
비교예comparative example 4 내지 14. 상기 4 to 14. above 실시예Example 12에 대해 일부 단독 성분과 For 12, some single components and 하이드롤라이즈드콜라겐을hydrolyzed collagen 혼합한 실험용 조성물의 제조 Preparation of Mixed Experimental Compositions
글리세린 8.31 중량%와 잔량의 하이드롤라이즈드콜라겐을 혼합한 비교예 4, 1,2-헥산다이올 3.66659 중량%와 잔량의 하이드롤라이즈드콜라겐을 혼합한 비교예 5, 다이프로필렌글라이콜 2.5 중량%와 잔량의 하이드롤라이즈드콜라겐을 혼합한 비교예 6, 나이아신아마이드 2.0 중량%와 잔량의 하이드롤라이즈드콜라겐을 혼합한 비교예 7, 정제수 1.252958753 중량%와 잔량의 하이드롤라이즈드콜라겐을 혼합한 비교예 8, 트레할로오스 1.0 중량% 잔량의 하이드롤라이즈드콜라겐을 혼합한 비교예 9, 부틸렌글라이콜 0.2335 중량%와 잔량의 하이드롤라이즈드콜라겐을 혼합한 비교예 10, 닥풀뿌리추출물 0.15 중량%와 잔량의 하이드롤라이즈드콜라겐을 혼합한 비교예 11, 프로판다이올 0.15 중량%와 잔량의 하이드롤라이즈드콜라겐을 혼합한 비교예 12, 폴리글리세릴10-라우레이트 0.15 중량%와 잔량의 하이드롤라이즈드콜라겐을 혼합한 비교예 13, 사이아노코발아민 0.001 중량%와 잔량의 하이드롤라이즈드콜라겐을 혼합한 비교예 14를 준비하였다. Comparative Example 4 in which 8.31% by weight of glycerin and the remaining amount of hydrolyzed collagen were mixed, Comparative Example 5 in which 3.66659% by weight of 1,2-hexanediol and the remaining amount of hydrolyzed collagen were mixed, and dipropylene glycol 2.5 Comparative Example 6 in which the weight % and the remaining amount of hydrolyzed collagen were mixed, Comparative Example 7 in which 2.0% by weight of niacinamide and the remaining amount of hydrolyzed collagen were mixed, and 1.252958753% by weight of purified water and the remaining amount of hydrolyzed collagen Comparative Example 8 mixed, Comparative Example 9 mixed with 1.0% by weight of trehalose and the remaining amount of hydrolyzed collagen, Comparative Example 10 mixed with 0.2335% by weight of butylene glycol and the remaining amount of hydrolyzed collagen, Dok Comparative Example 11 in which 0.15% by weight of grass root extract and the remaining amount of hydrolyzed collagen were mixed, Comparative Example 12 in which 0.15% by weight of propanediol and the remaining amount of hydrolyzed collagen were mixed, and 0.15% by weight of polyglyceryl 10-laurate Comparative Example 13 in which % and the remaining amount of hydrolyzed collagen were mixed, and Comparative Example 14 in which 0.001% by weight of cyanocobalamin and the remaining amount of hydrolyzed collagen were mixed were prepared.
비교예comparative example
15. 비교용 조성물 1의 제조 15. Preparation of
정제수 To100, 젤란검 0.15g, 스클레로튬검 0.15, 글리세린 5g, 1,2-헥산다이올 2g, 향료 적량, 피이지-40 하이드로제네이티드캐스터오일 향료의 5배 당량, 정제수 3g, 칼슘클로라이드 0.08g, 소듐시트레이트 0.04g의 조성을 참조하여 다음과 같이 제조하였다Purified water To100, gellan gum 0.15g, sclerotium gum 0.15,
정제수를 85℃까지 가온한 다음, 젤란검과 스클레로튬검을 첨가하여 5분간 교반한다. 그후 50℃까지 조성물을 냉각시킨 다음 글리세린을 혼합한다. 별도로 용해한 다이프로필렌글라이콜, 1,2-헥산다이올, 피이지-40 하이드로제네이티드캐스터오일, 향료를 조성물과 혼합한다. 혼합한 조성물을 거름망을 사이에 두고 진공펌프를 작동시켜 여과한다. 정제수를 사용하여 칼슘클로라이드, 소듐시트레이트를 별도의 용해조에 용해시킨다. 용해시킨 용액을 조성물에 여과하면서 투입한 다음 30℃까지 냉각하면서 교반한 후 배출한다.After warming the purified water to 85°C, gellan gum and sclerotium gum were added and stirred for 5 minutes. The composition is then cooled to 50° C. and then glycerin is mixed in. Separately dissolved dipropylene glycol, 1,2-hexanediol, PEG-40 hydrogenated castor oil, and fragrance are mixed with the composition. The mixed composition is filtered by operating a vacuum pump through a sieve. Dissolve calcium chloride and sodium citrate in a separate dissolving tank using purified water. The dissolved solution is added to the composition while filtering, and then cooled to 30° C. while stirring and then discharged.
비교예comparative example
16. 비교용 조성물 2의 제조 16. Preparation of
정제수 to100, Sodium Citrate 0.1중량%, Xylitol 0.5중량%, Glycerin 10.0중량%, Gellan Gum 0.4중량%, 정제수 10 중량%, Calcium Chloride 0.1중량%, 에탄올 0.1중량%, Methtlparaben 0.2중량%, Menthol 0.1중량%, Phenoxyethanol 0.3중량%, 향료 0.03중량%, 색소(적색 504호 0.1%) 0.2중량%의 조성을 참조하여 다음과 같이 제조하였다. Purified water to100, Sodium Citrate 0.1% by weight, Xylitol 0.5% by weight, Glycerin 10.0% by weight, Gellan Gum 0.4% by weight, Purified water 10% by weight, Calcium Chloride 0.1% by weight, Ethanol 0.1% by weight, Methtlparaben 0.2% by weight, Menthol 0.1% by weight , Phenoxyethanol 0.3% by weight, fragrance 0.03% by weight, pigment (Red No. 504 0.1%) 0.2% by weight of the composition was prepared as follows.
정제수에 구연산 나트륨(Sodium Citrate)와 자일리톨(Xylitol),글리세린(Glycerine)을 용해시킨 후 젤란검(Gellan Gum)을 첨가하여 85~90℃까지 가온/용해 한다. 이 용액에 별도로 정제수에 용해해 놓은 Calcium Chloride 용액을 첨가하고 3~5분간 충분히 교반 한다. 완전용해된 것을 확인 한 후 40℃까지 냉각한다. 별도로 용해한 에탄올, 향료, Methylparaben, 색소 등을 첨가한 후 homogenizer로 4000~5000 rpm 으로 분쇄한 후 탈기 공정을 거친 후 완료한다.After dissolving Sodium Citrate, Xylitol, and Glycerine in purified water, add Gellan Gum and heat/dissolve to 85~90℃. Add Calcium Chloride solution separately dissolved in purified water to this solution and stir sufficiently for 3 to 5 minutes. After confirming complete dissolution, cool to 40℃. Separately dissolved ethanol, fragrance, methylparaben, coloring, etc. are added, then pulverized with a homogenizer at 4000~5000 rpm, and the degassing process is completed.
비교예comparative example 17. 비교용 조성물 3의 제조 17. Preparation of Comparative Composition 3
다음의 공정으로 비교용 조성물 3을 제조하였다.Comparative composition 3 was prepared in the following process.
1) 메인 가마(용해조)에, 젤란검, 디소듐이디티에이, 판테놀, 판토락톤, 클로르페네신, 소듐시트레이트, 글리세린, 부틸렌글라이콜, 마데카소사이드, 해수 및 정제수를 포함하는 제1용액(A)을 투입하고 70 내지 80℃에서, 회전속도 1500 내지 2000 rpm, 10분동안 교반하여 용해하였다(20 rpm).1) In the main kiln (dissolving tank), an agent containing gellan gum, disodium EDTA, panthenol, pantolactone, chlorphenesin, sodium citrate, glycerin, butylene glycol, madecassoside, seawater and
2) 별도 용해조에서 젖산칼슘 및 해수를 포함하는 제2용액(B)을 제조한 다음 이를 상기 메인 가마에 투입하고 70 내지 80℃에서, 회전속도 3000 내지 3500 rpm, 20분 동안 교반하여 혼합하였다(20 rpm).2) After preparing the second solution (B) containing calcium lactate and seawater in a separate melting tank, it was put into the main kiln and mixed by stirring at 70 to 80 ° C. at a rotational speed of 3000 to 3500 rpm for 20 minutes ( 20 rpm).
3) 상기 메인 가마의 온도를 50 내지 60℃로 낮추고(20 rpm), 별도 용해조에서 PEG-60 하이드로제네이티드캐스터오일, 카프릴릴글라이콜, 에칠헥실글리세린, 페녹시에탄올, 향료 및 부틸렌글라이콜을 포함하는 C용액을 제조한 다음, 이를 상기 메인 가마에 투입하고 50 내지 60℃, 회전속도 3000 내지 3500 rpm으로 10분동안 교반하여 혼합하였다(20 rpm).3) The temperature of the main kiln is lowered to 50 to 60 ° C (20 rpm), and PEG-60 hydrogenated castor oil, caprylyl glycol, ethylhexyl glycerin, phenoxyethanol, fragrance and butylene glycol in a separate melting tank After preparing a C solution containing kohl, it was put into the main kiln and mixed by stirring at 50 to 60 ° C. and a rotational speed of 3000 to 3500 rpm for 10 minutes (20 rpm).
4) 상기 메인 가마의 온도를 40 내지 50℃로 낮추고(20 rpm), 상기 혼합물에, 제주조릿대추출물, 1,2-헥산디올, 병풀추출물, 수국잎추출물, 국화꽃추출물, 알로에베라잎추출물, 녹차추출물, 백합추출물, 마데카소사이드, 아시아티코사이드, 꿀풀추출물, 편백나무잎추출물 및 황금추출물을 포함하는 제4용액(D)을 순차적으로 혼합하며 회전속도 1000 내지 1500 rpm으로 10분 동안 교반하여 혼합하였다(20 rpm).4) The temperature of the main kiln was lowered to 40 to 50 ° C. (20 rpm), and to the mixture, Jeju saris extract, 1,2-hexanediol, centella asiatica extract, hydrangea leaf extract, chrysanthemum flower extract, aloe vera leaf extract, The fourth solution (D) containing green tea extract, lily extract, madecassoside, asiaticoside, Lamiaceae extract, cypress leaf extract and gold extract was sequentially mixed and stirred at a rotational speed of 1000 to 1500 rpm for 10 minutes. Mixed (20 rpm).
5) 상기 혼합물을 냉각한 다음 메인 가마로부터 배출한 다음 25 내지 30℃에서 1일 동안 숙성시켜 겔화하였다. 이 때 겔화 상태를 필수적으로 확인한다.5) The mixture was cooled, discharged from the main kiln, and aged at 25 to 30° C. for 1 day to gel. At this time, the gelation state is essential.
5) 상기 혼합물을 냉각한 다음 메인 가마로부터 배출한 다음 25 내지 30℃에서 1일 동안 숙성시켜 겔화하였다. 이 때 겔화 상태를 필수적으로 확인한다.5) The mixture was cooled, discharged from the main kiln, and aged at 25 to 30° C. for 1 day to gel. At this time, the gelation state is essential.
6) 상기 겔화물을 25 내지 30℃에서 분쇄 상태를 눈으로 확인하면서 아지믹서로 A.M 500 내지 1000rpm으로 분쇄하였다. 이 때 분쇄시 입자 사이즈 확인한다.6) The gel material was pulverized at 500 to 1000 rpm with an A.M. mixer at 25 to 30 ° C. while visually checking the pulverization state. At this time, check the particle size during grinding.
7) 상기 분쇄물에 메인 가마에 투입한 후, 카프릴릭/카프릭트리글리세라이드, 부틸렌글라이콜, 카라기난가루, 아가, 알긴, 젤란검, 한련초추출물, 인도멀구슬나무잎추출물, 드럼스틱씨오일, 동백나무씨오일 및 정제수를 포함하는 분산액(E)을 25 내지 30℃에서 혼합하여 분산시켰다(20 rpm). 이때 캐뷸 분산 확인하고 깨짐 유의한다.7) After putting the pulverized material into the main kiln, caprylic/capric triglyceride, butylene glycol, carrageenan powder, agar, algin, gellan gum, nasturtium extract, Indian mulberry leaf extract, drumstick seeds A dispersion (E) containing oil, camellia seed oil, and purified water was mixed and dispersed at 25 to 30° C. (20 rpm). At this time, check the cabule dispersion and note the breakage.
8) 상기 제조된 조성물을 완전탈포 및 미여과 배출을 수행하여 최종 제형을 얻었다. 또한, 품질 검사도 수행하였다.8) The prepared composition was completely degassed and unfiltered discharged to obtain a final formulation. In addition, quality inspection was also performed.
상기 비교용 조성물 3은 단계 1)과 관련하여, 해수 54470g, 디소듐이디티에이 20g, 판테놀 3750g, 판토락톤 50g, 정제수 1200g, 클로르페내신 200g, 소듐시트레이트 50g, 글리세린 9000g, 부틸렌글라이콜 6000g, 마데카소사이드 10g, 젤란검200g, 단계 2)와 관련하여, 해수 10000g, 젖산칼슘 200g, 단계 3)과 관련하여, 피이지-60 하이드로제네이티드캐스터오일 200g, 카프릴릴글라이콜 100g, 에칠헥실글리세린 100g, 페녹시에탄올 200g, 향료 20g, 부틸렌글라이콜 3000g, 단계 4)와 관련하여, 제주조릿대추출물 8820g, 1,2-헥산디올 204.6g, 병풀추출물 294.0g, 수국잎추출물 196.0g, 국화꽃추출물 196.0g, 알로에베라잎추출물 196.0g, 녹차추출물 196.0g, 백합추출물 98.0g, 마데카소사이드 0.00001g, 아시아티코사이드 0.00001g, 꿀풀추출물 9.8g, 편백나무잎추출물 9.8g, 황금추출물 9.8g, 단계 5)와 관련하여, 카프릴릭/카프릭트리글리세라이드 502g, 부틸렌글라이콜 10g, 카라기난가루 1g, 아가 1g, 알긴 1g, 젤란검 1g, 한련초추출물 1g, 인도멀구슬나무잎추출물 1g, 드럼스틱씨오일 1g, 동백나무씨오일 1g 및 정제수 470g의 조성을 따른다. Comparative composition 3, in relation to step 1), 54470 g of seawater, 20 g of disodium EDTA, 3750 g of panthenol, 50 g of pantolactone, 1200 g of purified water, 200 g of chlorphenacin, 50 g of sodium citrate, 9000 g of glycerin, butylene glycol Col 6000g, madecassoside 10g, gellan gum 200g, in relation to step 2), seawater 10000g, calcium lactate 200g, in relation to step 3), PEG-60 hydrogenated castor oil 200g, caprylyl glycol 100g , ethylhexylglycerin 100g, phenoxyethanol 200g, fragrance 20g, butylene glycol 3000g, in relation to step 4), 8820g of Jeju bamboo grass extract, 1,2-hexanediol 204.6g, centella asiatica extract 294.0g, hydrangea leaf extract 196.0 g, Chrysanthemum Flower Extract 196.0g, Aloe Vera Leaf Extract 196.0g, Green Tea Extract 196.0g, Lily Extract 98.0g, Madecassoside 0.00001g, Asiaticoside 0.00001g, Lamiaceae Extract 9.8g, Cypress Leaf Extract 9.8g, Gold 9.8 g of extract, in relation to step 5), 502 g of caprylic/capric triglyceride, 10 g of butylene glycol, 1 g of carrageenan powder, 1 g of agar, 1 g of algin, 1 g of gellan gum, 1 g of nasturtium extract, Indian mulberry leaf It follows the composition of extract 1g, drumstick seed oil 1g, camellia seed oil 1g and purified water 470g.
제조예manufacturing example 1. 분사용 1. Spraying 젤타입gel type 화장료cosmetics 조성물의 제조 preparation of the composition
하기 표 16의 조성으로 제조예 1의 분사용 젤타입 화장료 조성물을 제조하였다. A spraying gel-type cosmetic composition of Preparation Example 1 was prepared with the composition shown in Table 16 below.
실험예Experimental example 1. 실험용 조성물의 분사 성능 확인 1. Confirmation of the spraying performance of the experimental composition
각 조성물의 분사 성능을 확인하기 위하여 분사각 및 분산력을 확인하는 실험을 진행하였다. In order to confirm the spray performance of each composition, an experiment was conducted to check the spray angle and dispersion force.
분사각의 확인 실험은 실시예 1 내지 12, 비교예 1 내지 14, 제조예 1에서 제조한 조성물을 동일 펌프가 달린 동일용기에 동량을 충진한 후 검은 판을 뒤에 대고 3회 분사 후 분사각을 비교하여 측정하였다.In the experiment to confirm the spray angle, the same amount of the composition prepared in Examples 1 to 12, Comparative Examples 1 to 14, and Preparation Example 1 was filled in the same container with the same pump, and then sprayed three times with a black plate behind the spray angle. measured by comparison.
분산력의 확인 실험은 A4 용지에 20cm 거리에서 3회 분사 후 분산된 정도를 20명의 전문가 측정에 따라 육안으로 확인하였다. 분사력의 정도는 전문가의 측정에 따라 5점척도법로 평가하였다. The dispersion force confirmation experiment was visually confirmed according to the measurement of 20 experts after spraying three times at a distance of 20 cm on A4 paper. The degree of blowing force was evaluated by a 5-point scale method according to the expert's measurement.
실험결과는 하기 표 17과 같으며, 각 측정값을 평균하여 기록하였다. The experimental results are shown in Table 17 below, and each measured value was averaged and recorded.
그 결과 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 중 어느 하나 이상이 결여된 비교예 1 내지 14의 경우 분사각 및 분산력이 월등히 떨어졌음을 확인할 수 있었다. 그에 비해, 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트가 모두 포함된 실시예 1의 경우 분사각 및 분산력이 비교예 1 내지 14에 비해 월등히 우수하였으며, 그 외에 성분들을 추가할수록 점진적으로 향상되는 것을 확인할 수 있었다. 제조예 1의 경우 가장 우수한 분사각 및 분산력을 나타냈다. As a result, in the case of Comparative Examples 1 to 14 lacking any one or more of hydrolyzed collagen, gellan gum, and calcium lactate, it was confirmed that the spray angle and dispersion force were significantly lowered. In contrast, in the case of Example 1 containing all of hydrolyzed collagen, gellan gum, and calcium lactate, the spray angle and dispersing power were far superior to those of Comparative Examples 1 to 14, and gradually improved as other components were added. could confirm that Preparation Example 1 showed the best spray angle and dispersion.
실험예Experimental example 2. 제품 사용성 평가 2. Product usability evaluation
상기 실시예 1 내지 12, 비교예 1 내지 14, 제조예 1에서 제조한 조성물의 사용성을 평가하기 위해 피부에 도포한 후의 느낌을 20∼30세의 전문 남성 패널 20명을 대상으로 본 시료를 10회 분사한 후, 하기 항목에 대해 5점 평가법(사용감이 좋을수록 5점 사용감이 낮을수록 1점)으로 평가하여 평균치를 표 18에 나타내었다. In order to evaluate the usability of the compositions prepared in Examples 1 to 12, Comparative Examples 1 to 14, and Preparation Example 1, 20 professional male panels aged 20 to 30 were tested for the feeling after application to the skin, and this sample was 10 After spraying, the following items were evaluated by a 5-point evaluation method (5 points for better feeling of use and 1 point for lower feeling of use), and the average values are shown in Table 18.
그 결과 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 중 어느 하나 이상이 결여된 비교예 1 내지 14의 경우 퍼짐성, 흡수력, 끈적임 등이 월등히 떨어졌음을 확인할 수 있었다. 그에 비해, 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트가 모두 포함된 실시예 1의 경우 퍼짐성, 흡수력, 끈적임 등이 비교예 1 내지 14에 비해 월등히 우수하였으며, 그 외에 성분들을 추가할수록 점진적으로 향상되는 것을 확인할 수 있었다. 제조예 1의 경우 퍼짐성, 흡수력, 끈적임 등에서 가장 우수한 평가점수를 나타냈다. As a result, in the case of Comparative Examples 1 to 14 lacking any one or more of hydrolyzed collagen, gellan gum, and calcium lactate, it was confirmed that spreadability, absorbency, stickiness, etc. were significantly lowered. In contrast, in the case of Example 1 containing all of hydrolyzed collagen, gellan gum, and calcium lactate, the spreadability, absorbency, and stickiness were far superior to those of Comparative Examples 1 to 14, and the more components were added, the more gradually improvement could be observed. In the case of Preparation Example 1, the best evaluation scores were obtained in terms of spreadability, absorbency, and stickiness.
실험예Experimental example 3. 보습 효과 확인 3. Check the moisturizing effect
상기 실시예 1 내지 12, 비교예 1 내지 14, 제조예 1에서 제조한 조성물에 대하여 보습효과를 확인하였다. 실험은 공지된 방법을 통해 수행되었다. The moisturizing effect of the compositions prepared in Examples 1 to 12, Comparative Examples 1 to 14, and Preparation Example 1 was confirmed. Experiments were conducted through known methods.
상기 실시예 1 내지 12, 비교예 1 내지 14, 제조예 1에서 제조한 조성물을 피시험자(20세-45세의 남성 및 여성) 30명을 대상으로 1일 2회씩 4주간 안면 양쪽의 얼굴 및 전반부에 실시예 1 내지 12, 비교예 1 내지 14, 제조예 1에서 제조한 조성물을 각각 도포하여 도포하기 전, 2주 경과 후, 그리고 4주경과 후의 피부보습개선상태를 피부수분측정기 Corneometer CM 820 (Courage + Khazaka, Germany)를 이용하여 측정하였으며, 단위는 기기에서 부여하는 임의의 단위(Arbitrary Unit, AU)로 표현되며, 측정값이 높을수록 피부표면에 수분량이 높음을 의미한다.The compositions prepared in Examples 1 to 12, Comparative Examples 1 to 14, and Preparation Example 1 were applied to 30 subjects (males and females aged 20 to 45 years old) twice a day for 4 weeks on both sides of the face and In the first half, the compositions prepared in Examples 1 to 12, Comparative Examples 1 to 14, and Preparation Example 1 were applied, respectively, and the skin moisture improvement status before application, after 2 weeks, and after 4 weeks was measured using a skin moisture meter Corneometer CM 820 It was measured using (Courage + Khazaka, Germany), and the unit is expressed as an arbitrary unit (Arbitrary Unit, AU) given by the device, and the higher the measured value, the higher the moisture content on the skin surface.
그 결과 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 중 어느 하나 이상이 결여된 비교예 1 내지 14의 경우 피부 보습효과가 월등히 떨어짐을 확인할 수 있었다. 그에 비해, 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트가 모두 포함된 실시예 1의 경우 피부 보습효과가 비교예 1 내지 14에 비해 월등히 우수하였으며, 그 외에 성분들을 추가할수록 점진적으로 향상되는 것을 확인할 수 있었다. 제조예 1의 경우 가장 우수한 피부 보습효과를 나타냈다. As a result, in the case of Comparative Examples 1 to 14 lacking any one or more of hydrolyzed collagen, gellan gum and calcium lactate, it was confirmed that the skin moisturizing effect was significantly reduced. In contrast, in the case of Example 1 containing all of hydrolyzed collagen, gellan gum and calcium lactate, the skin moisturizing effect was far superior to that of Comparative Examples 1 to 14, and it gradually improved as more ingredients were added. I was able to confirm. In the case of Preparation Example 1, it showed the best skin moisturizing effect.
결론. conclusion.
상기 실시예, 비교예, 제조예를 통해 수행된 실험예 1 내지 3에서 확인할 수 있듯이, 본 발명에 따른 분사용 젤타입 화장료 조성물은 본사 성능, 제품 사용성, 보습효과가 우수함을 확인할 수 있었다. As can be seen in Experimental Examples 1 to 3 performed through the above Examples, Comparative Examples, and Preparation Examples, it was confirmed that the gel-type cosmetic composition for spraying according to the present invention has excellent performance, product usability, and moisturizing effect.
실험예 1을 통하여, 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 모두를 포함하는 실시예 1 내지 12의 경우, 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 중 어느 하나 이상이 결여된 비교예에 비해 분사각 및 분산력이 우수하였으며, 이와 더불어, 사이아노코발아민, 글리세린, 1,2-헥산다이올, 다이프로필렌글라이콜, 나이아신아마이드, 정제수, 트레할로오스, 부틸렌글라이콜, 닥풀뿌리추출물, 프로판다이올, 폴리글리세릴10-라우레이트를 각각 추가함에 따라 점진적으로 분사각 및 분산력이 우수함을 확인하였으며, 이를 통해, 이들의 조합에 따라 예기치 못한 효과가 발생하였음을 확인할 수 있었다. Through Experimental Example 1, in the case of Examples 1 to 12 including all of hydrolyzed collagen, gellan gum and calcium lactate, comparison lacking any one or more of hydrolyzed collagen, gellan gum and calcium lactate Compared to Example, the spray angle and dispersibility were excellent, and in addition, cyanocobalamin, glycerin, 1,2-hexanediol, dipropylene glycol, niacinamide, purified water, trehalose, butylene glycol, As mulberry root extract, propanediol, and polyglyceryl 10-laurate were added, respectively, it was confirmed that the spray angle and dispersion power were gradually improved, and through this, it was confirmed that unexpected effects occurred depending on their combination. .
실험예 2를 통하여, 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 모두를 포함하는 실시예 1 내지 12의 경우, 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 중 어느 하나 이상이 결여된 비교예에 비해 퍼짐성, 흡수력, 끈적임을 포함하는 제품 사용성이 우수하였으며, 이와 더불어, 사이아노코발아민, 글리세린, 1,2-헥산다이올, 다이프로필렌글라이콜, 나이아신아마이드, 정제수, 트레할로오스, 부틸렌글라이콜, 닥풀뿌리추출물, 프로판다이올, 폴리글리세릴10-라우레이트를 각각 추가함에 따라 점진적으로 흡수력, 끈적임을 포함하는 제품 사용성이 우수함을 확인하였으며, 이를 통해, 이들의 조합에 따라 예기치 못한 효과가 발생하였음을 확인할 수 있었다. Through Experimental Example 2, in the case of Examples 1 to 12 containing all of hydrolyzed collagen, gellan gum and calcium lactate, comparison lacking any one or more of hydrolyzed collagen, gellan gum and calcium lactate Compared to Example, product usability including spreadability, absorbency, and stickiness was excellent, and in addition, cyanocobalamin, glycerin, 1,2-hexanediol, dipropylene glycol, niacinamide, purified water, trehalose , As butylene glycol, mulberry root extract, propanediol, and polyglyceryl 10-laurate were added, respectively, it was confirmed that the usability of the product, including absorption and stickiness, was excellent. It was confirmed that an unexpected effect occurred.
실험예 2를 통하여, 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 모두를 포함하는 실시예 1 내지 12의 경우, 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트 중 어느 하나 이상이 결여된 비교예에 비해 보습효과가 우수하였으며, 이와 더불어, 사이아노코발아민, 글리세린, 1,2-헥산다이올, 다이프로필렌글라이콜, 나이아신아마이드, 정제수, 트레할로오스, 부틸렌글라이콜, 닥풀뿌리추출물, 프로판다이올, 폴리글리세릴10-라우레이트를 각각 추가함에 따라 점진적으로 보습효과가 우수함을 확인하였으며, 이를 통해, 이들의 조합에 따라 예기치 못한 효과가 발생하였음을 확인할 수 있었다. Through Experimental Example 2, in the case of Examples 1 to 12 containing all of hydrolyzed collagen, gellan gum and calcium lactate, comparison lacking any one or more of hydrolyzed collagen, gellan gum and calcium lactate Compared to Example, the moisturizing effect was excellent, and in addition, cyanocobalamin, glycerin, 1,2-hexanediol, dipropylene glycol, niacinamide, purified water, trehalose, butylene glycol, mulberry root As the extract, propanediol, and polyglyceryl 10-laurate were added, respectively, it was confirmed that the moisturizing effect was gradually improved, and through this, it was confirmed that an unexpected effect occurred according to the combination thereof.
이에, 본 발명은 하이드롤라이즈드콜라겐, 젤란검 및 칼슘락테이트를 유효성분으로 포함하여, 각종 분사용기에 용이하게 적용 가능한 분사용 제형을 형성할 수 있음은 물론, 피부에 유용한 피부컨디셔닝제의 활성성분을 촉진하여, 피부 관리 효과가 탁월한 분사용 젤타입 화장료 조성물을 개발하였음을 명시한다. Accordingly, the present invention includes hydrolyzed collagen, gellan gum, and calcium lactate as active ingredients to form a spray formulation that can be easily applied to various spray devices, as well as a skin conditioning agent useful for the skin. It is stated that a gel-type cosmetic composition for spraying with excellent skin care effect was developed by promoting active ingredients.
본 발명을 첨부된 도면과 함께 설명하였으나, 이는 본 발명의 요지를 포함하는 다양한 실시 형태 중의 하나의 실시 예에 불과하며, 당 업계에서 통상의 지식을 가진 자가 용이하게 실시할 수 있도록 하는 데에 그 목적이 있는 것으로, 본 발명은 상기 설명된 실시예에만 국한되는 것이 아님은 명확하다. 따라서, 본 발명의 보호범위는 하기의 청구범위에 의해 해석되어야 하며, 본 발명의 요지를 벗어나지 않는 범위 내에서 변경, 치환, 대체 등에 의해 그와 동등한 범위 내에 있는 모든 기술 사상은 본 발명의 권리에 포함될 것이다. 또한, 도면의 일부 구성은 구성을 보다 명확하게 설명하기 위한 것으로 실제보다 과장되거나 축소되어 제공되는 것임을 명확히 한다.Although the present invention has been described with the accompanying drawings, this is only one example of various embodiments including the gist of the present invention, and is intended to be easily practiced by those skilled in the art. As an object, it is clear that the present invention is not limited to the embodiments described above. Therefore, the protection scope of the present invention should be interpreted by the following claims, and all technical ideas within the equivalent range by change, substitution, substitution, etc. within the scope of the present invention do not depart from the scope of the present invention. will be included In addition, it is clear that some configurations in the drawings are provided exaggerated or reduced than the actual configuration to more clearly explain the configuration.
Claims (5)
A spraying gel-type cosmetic composition comprising hydrolyzed collagen, gellan gum, calcium lactate and cyanocobalamin as active ingredients.
상기 하이드롤라이즈드콜라겐, 젤란검, 칼슘락테이트 및 사이아노코발아민 외에,
자일리틸글루코사이드, 안하이드로자일리톨, 자일리톨, 글리세린, 글루코오스, 하이드록시프로필트라이모늄하이알루로네이트, 하이드롤라이즈드하이알루로닉애씨드, 소듐아세틸레이티드하이알루로네이트, 소듐하이알루로네이트크로스폴리머, 트레할로오스로 이루어지는 군에서 선택된 1종 이상의 보습제를 더 포함하는 것을 특징으로 하는 분사용 젤타입 화장료 조성물.
According to claim 1,
In addition to the hydrolyzed collagen, gellan gum, calcium lactate and cyanocobalamin,
Xylityl Glucoside, Anhydroxylitol, Xylitol, Glycerin, Glucose, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Sodium Hyaluronate Crosspolymer , A gel-type cosmetic composition for spraying, characterized in that it further comprises at least one moisturizer selected from the group consisting of trehalose.
상기 하이드롤라이즈드콜라겐, 젤란검, 칼슘락테이트 및 사이아노코발아민 외에,
정제수, 1,2-헥산다이올, 다이프로필렌글라이콜, 프로판다이올, 부틸렌글라이콜로 이루어지는 군에서 선택된 1종 이상의 용제를 더 포함하는 것을 특징으로 하는 분사용 젤타입 화장료 조성물.
According to claim 1,
In addition to the hydrolyzed collagen, gellan gum, calcium lactate and cyanocobalamin,
Purified water, 1,2-hexanediol, dipropylene glycol, propanediol, at least one solvent selected from the group consisting of butylene glycol spraying gel-type cosmetic composition characterized in that it further comprises.
상기 하이드롤라이즈드콜라겐, 젤란검, 칼슘락테이트 및 사이아노코발아민 외에,
닥풀뿌리추출물, 연꽃추출물, 개똥쑥추출물, 쌀추출물, 효모발효물, 두충나무껍질추출물, 병풀추출물, 아시아티코사이드, 마데카식애씨드, 아시아틱애씨드, 마데카소사이드 아데노신, 소듐하이알루로네이트, 나이아신아마이드, 수크로오스스테아레이트, 하이알루로닉애씨드, 하이드롤라이즈드소듐하이알루로네이트, 포타슘하이알루로네이트, 하이드로제네이티드포스파티딜콜린, 카프릴릭/카프릭트라이글리세라이드, 세테아릴알코올로 이루어지는 군에서 선택된 1종 이상의 피부컨디셔닝제를 더 포함하는 것을 특징으로 하는 분사용 젤타입 화장료 조성물.
According to claim 1,
In addition to the hydrolyzed collagen, gellan gum, calcium lactate and cyanocobalamin,
Mulberry Root Extract, Lotus Extract, Artemisia Extract, Rice Extract, Yeast Fermentation, Eucommia Bark Extract, Centella Asiatica Extract, Asiaticoside, Madecassic Acid, Asiatic Acid, Madecassoside Adenosine, Sodium Hyaluronate, Niacin Amide, sucrose stearate, hyaluronic acid, hydrolyzed sodium hyaluronate, potassium hyaluronate, hydrogenated phosphatidylcholine, caprylic/capric triglyceride, cetearyl alcohol A gel-type cosmetic composition for spraying, characterized in that it further comprises at least one skin conditioning agent selected from.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102591077B1 (en) * | 2023-06-29 | 2023-10-20 | 주식회사 스킨앤플러스 | Cosmetic composition |
KR102621138B1 (en) * | 2023-05-12 | 2024-01-05 | 주식회사 포레스트에비뉴 | Sheet-free foam mask pack composition and foam mask pack using the same |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012201661A (en) * | 2011-03-28 | 2012-10-22 | Kose Corp | Vesicle-containing composition, and cosmetic or skin care preparation including the same |
KR102135047B1 (en) | 2018-12-24 | 2020-07-17 | 그린코스 주식회사 | Manufacturing method of spray gel type cosmetic composition |
-
2022
- 2022-08-25 KR KR1020220106945A patent/KR102506839B1/en active IP Right Grant
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012201661A (en) * | 2011-03-28 | 2012-10-22 | Kose Corp | Vesicle-containing composition, and cosmetic or skin care preparation including the same |
KR102135047B1 (en) | 2018-12-24 | 2020-07-17 | 그린코스 주식회사 | Manufacturing method of spray gel type cosmetic composition |
Non-Patent Citations (1)
Title |
---|
메디필 펩타이드9 아쿠아 볼륨 톡스 미스트 전성분, 네이버 블로그, [online], 인터넷: <URL: https://blog.naver.com/fgsgffsdf34/222400241415>, 페이지 1-9(2021.06.16.)* * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102621138B1 (en) * | 2023-05-12 | 2024-01-05 | 주식회사 포레스트에비뉴 | Sheet-free foam mask pack composition and foam mask pack using the same |
KR102591077B1 (en) * | 2023-06-29 | 2023-10-20 | 주식회사 스킨앤플러스 | Cosmetic composition |
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