KR102487684B1 - 축합 고리계로 치환된 아졸린 화합물 - Google Patents

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Publication number

KR102487684B1

KR102487684B1 KR1020177020619A KR20177020619A KR102487684B1 KR 102487684 B1 KR102487684 B1 KR 102487684B1 KR 1020177020619 A KR1020177020619 A KR 1020177020619A KR 20177020619 A KR20177020619 A KR 20177020619A KR 102487684 B1 KR102487684 B1 KR 102487684B1

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KR

South Korea

Prior art keywords

spp

compound

formula

alkyl

methyl

Prior art date

2014-12-22

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

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• AEKNYBWUEYNWMJ-QWOOXDRHSA-N Pramiconazole Chemical group O=C1N(C(C)C)CCN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@@H]3O[C@](CN4N=CN=C4)(CO3)C=3C(=CC(F)=CC=3)F)=CC=2)C=C1 AEKNYBWUEYNWMJ-QWOOXDRHSA-N 0.000 title 1
• 150000001875 compounds Chemical class 0.000 claims abstract description 703
• 239000000203 mixture Substances 0.000 claims abstract description 107
• 241000607479 Yersinia pestis Species 0.000 claims abstract description 70
• 239000000463 material Substances 0.000 claims abstract description 46
• -1 C 1 -C 6 -alkyl Chemical group 0.000 claims description 458
• 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 claims description 95
• 150000003839 salts Chemical class 0.000 claims description 88
• 239000001257 hydrogen Substances 0.000 claims description 75
• 229910052739 hydrogen Inorganic materials 0.000 claims description 75
• SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims description 53
• 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 48
• 125000001424 substituent group Chemical group 0.000 claims description 48
• 238000000034 method Methods 0.000 claims description 47
• 241001465754 Metazoa Species 0.000 claims description 40
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 36
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 35
• 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims description 33
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 29
• 125000000623 heterocyclic group Chemical group 0.000 claims description 24
• 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims description 23
• 125000004432 carbon atom Chemical group C* 0.000 claims description 22
• 125000004093 cyano group Chemical group *C#N 0.000 claims description 21
• 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims description 19
• 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims description 18
• 229910052736 halogen Inorganic materials 0.000 claims description 17
• 150000002367 halogens Chemical class 0.000 claims description 17
• 229910052801 chlorine Inorganic materials 0.000 claims description 15
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 15
• 239000007787 solid Substances 0.000 claims description 15
• 206010061217 Infestation Diseases 0.000 claims description 14
• 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 claims description 13
• 229910052731 fluorine Inorganic materials 0.000 claims description 13
• 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 claims description 12
• 125000006656 (C2-C4) alkenyl group Chemical group 0.000 claims description 12
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• 125000004749 (C1-C6) haloalkylsulfinyl group Chemical group 0.000 claims description 10
• 125000006771 (C1-C6) haloalkylthio group Chemical group 0.000 claims description 10
• 230000000361 pesticidal effect Effects 0.000 claims description 10
• 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 claims description 9
• 239000007788 liquid Substances 0.000 claims description 9
• 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 9
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• 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 claims description 7
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• 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims description 7
• SLGOCMATMKJJCE-UHFFFAOYSA-N 1,1,1,2-tetrachloro-2,2-difluoroethane Chemical compound FC(F)(Cl)C(Cl)(Cl)Cl SLGOCMATMKJJCE-UHFFFAOYSA-N 0.000 claims description 5
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• 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 10
• 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 description 9
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• 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 description 8
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