KR102468174B1 - 멀티플렉스 pcr 수행 방법 - Google Patents

멀티플렉스 pcr 수행 방법 Download PDF

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KR102468174B1
KR102468174B1 KR1020197007698A KR20197007698A KR102468174B1 KR 102468174 B1 KR102468174 B1 KR 102468174B1 KR 1020197007698 A KR1020197007698 A KR 1020197007698A KR 20197007698 A KR20197007698 A KR 20197007698A KR 102468174 B1 KR102468174 B1 KR 102468174B1
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nucleic acid
oligonucleotide
moiety
target nucleic
quenching
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KR20190046881A (ko
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이고르 코즐로프
아마르 굽타
랜덜 사이키
앨리슨 찬
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에프. 호프만-라 로슈 아게
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    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
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    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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    • C12Q2561/113—Real time assay
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020197007698A 2016-09-15 2017-09-15 멀티플렉스 pcr 수행 방법 Active KR102468174B1 (ko)

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Application Number Priority Date Filing Date Title
US201662395325P 2016-09-15 2016-09-15
US62/395,325 2016-09-15
US201662435595P 2016-12-16 2016-12-16
US62/435,595 2016-12-16
US201762536871P 2017-07-25 2017-07-25
US62/536,871 2017-07-25
PCT/EP2017/073288 WO2018050824A1 (en) 2016-09-15 2017-09-15 Methods for performing multiplexed pcr

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KR20190046881A KR20190046881A (ko) 2019-05-07
KR102468174B1 true KR102468174B1 (ko) 2022-11-17

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US (3) US11028433B2 (OSRAM)
EP (2) EP3512959B1 (OSRAM)
JP (2) JP7221199B2 (OSRAM)
KR (2) KR102468633B1 (OSRAM)
CN (2) CN109689889A (OSRAM)
AU (2) AU2017328617B2 (OSRAM)
CA (2) CA3036119C (OSRAM)
DK (1) DK3512959T3 (OSRAM)
ES (2) ES2893411T3 (OSRAM)
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