KR102450885B1 - 3차원 구조물의 첨삭 가공을 위한 장치 및 방법 - Google Patents

3차원 구조물의 첨삭 가공을 위한 장치 및 방법 Download PDF

Info

Publication number
KR102450885B1
KR102450885B1 KR1020217023756A KR20217023756A KR102450885B1 KR 102450885 B1 KR102450885 B1 KR 102450885B1 KR 1020217023756 A KR1020217023756 A KR 1020217023756A KR 20217023756 A KR20217023756 A KR 20217023756A KR 102450885 B1 KR102450885 B1 KR 102450885B1
Authority
KR
South Korea
Prior art keywords
print head
hydrogel
fluid
channel
dispensing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020217023756A
Other languages
English (en)
Korean (ko)
Other versions
KR20210097816A (ko
Inventor
시몬 트레비스 베이어
콘라드 와루스
타머 모하메드
아나스 암제드 모하메드 비소울
Original Assignee
애스펙트 바이오시스템즈 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52021536&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR102450885(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 애스펙트 바이오시스템즈 리미티드 filed Critical 애스펙트 바이오시스템즈 리미티드
Publication of KR20210097816A publication Critical patent/KR20210097816A/ko
Application granted granted Critical
Publication of KR102450885B1 publication Critical patent/KR102450885B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B29C64/112—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using individual droplets, e.g. from jetting heads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/20—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/20—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B29C64/205—Means for applying layers
    • B29C64/209—Heads; Nozzles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30—Auxiliary operations or equipment
    • B29C64/386—Data acquisition or data processing for additive manufacturing
    • B29C64/393—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C70/00—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y30/00—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/015—Ink jet characterised by the jet generation process
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0058—Liquid or visquous
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0058—Liquid or visquous
    • B29K2105/0061—Gel or sol
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00—Data acquisition or data processing for additive manufacturing
    • B33Y50/02—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Mechanical Engineering (AREA)
  • Sustainable Development (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Composite Materials (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Coating Apparatus (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
KR1020217023756A 2013-06-13 2014-06-13 3차원 구조물의 첨삭 가공을 위한 장치 및 방법 Active KR102450885B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361834420P 2013-06-13 2013-06-13
US61/834,420 2013-06-13
KR1020167000859A KR102284531B1 (ko) 2013-06-13 2014-06-13 3차원 구조물의 첨삭 가공을 위한 장치 및 방법
PCT/CA2014/050556 WO2014197999A1 (en) 2013-06-13 2014-06-13 System for additive manufacturing of three-dimensional structures and method for same

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020167000859A Division KR102284531B1 (ko) 2013-06-13 2014-06-13 3차원 구조물의 첨삭 가공을 위한 장치 및 방법

Publications (2)

Publication Number Publication Date
KR20210097816A KR20210097816A (ko) 2021-08-09
KR102450885B1 true KR102450885B1 (ko) 2022-10-06

Family

ID=52021536

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020217023756A Active KR102450885B1 (ko) 2013-06-13 2014-06-13 3차원 구조물의 첨삭 가공을 위한 장치 및 방법
KR1020167000859A Active KR102284531B1 (ko) 2013-06-13 2014-06-13 3차원 구조물의 첨삭 가공을 위한 장치 및 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020167000859A Active KR102284531B1 (ko) 2013-06-13 2014-06-13 3차원 구조물의 첨삭 가공을 위한 장치 및 방법

Country Status (17)

Country Link
US (4) US11046930B2 (enExample)
EP (3) EP4628285A3 (enExample)
JP (5) JP6550379B2 (enExample)
KR (2) KR102450885B1 (enExample)
CN (1) CN105579219B (enExample)
AU (1) AU2014280825B2 (enExample)
BR (1) BR112015031320B1 (enExample)
CA (1) CA2915737C (enExample)
DK (2) DK3670155T3 (enExample)
ES (2) ES3035595T3 (enExample)
FI (1) FI3670155T3 (enExample)
IL (1) IL243014B (enExample)
PL (2) PL3670155T3 (enExample)
PT (2) PT3670155T (enExample)
RU (1) RU2643138C2 (enExample)
SG (1) SG11201510138RA (enExample)
WO (1) WO2014197999A1 (enExample)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140039662A1 (en) * 2012-07-31 2014-02-06 Makerbot Industries, Llc Augmented three-dimensional printing
PT3670155T (pt) 2013-06-13 2025-07-08 Aspect Biosystems Ltd Cabeça de impressão, sistema de fabrico aditivo de estruturas tridimensionais e respetivo método
EP3065875A4 (en) * 2013-11-04 2018-02-07 University of Iowa Research Foundation Bioprinter and methods of using same
AU2015223035A1 (en) 2014-02-26 2016-09-22 Luma Therapeutics, Inc. Ultraviolet phototherapy apparatuses and methods
US20160318260A1 (en) * 2015-04-30 2016-11-03 Elwha Llc Printing systems and related methods
DE102015206813A1 (de) * 2015-04-15 2016-10-20 Robert Bosch Gmbh Vorrichtung und Verfahren zum Auftragen eines Fluids auf einen Werkstückträger zum Erzeugen eines Werkstücks und System zum Erzeugen eines Werkstücks
CN107532134B (zh) * 2015-04-29 2021-11-09 米兰综合工科大学 用于三维细胞和/或组织构建体的产生和/或培养和/或成熟的微流体设备和相关方法
EP3302442B1 (en) 2015-06-03 2024-10-16 Triastek, Inc. Dosage forms and use thereof
DK4130243T3 (da) 2015-06-16 2024-09-30 Aspect Biosystems Ltd Kontinuerligt, bioprintet flerlagsvævsstruktur
EP3349967B1 (en) 2015-09-16 2022-10-26 Applied Materials, Inc. Printhead module for additive manufacturing system
EP3349969A4 (en) 2015-09-16 2019-05-22 Applied Materials, Inc. ARRANGEMENT OF PRESSURE HEAD MODULES FOR A GENERATIVE MANUFACTURING SYSTEM
US10961496B2 (en) 2015-12-04 2021-03-30 EMULATE, Inc. Open-top microfluidic device with structural anchors
US10026674B2 (en) 2015-12-22 2018-07-17 Raytheon Company Cooling structure for integrated circuits and methods for forming such structure
EP3398776B1 (en) * 2015-12-30 2021-12-01 Revotek Co., Ltd Biological printer nozzle component and biological printer
EP3409454B1 (en) * 2016-01-25 2023-03-01 Ricoh Company, Ltd. Three-dimensional molded object, method for producing three-dimensional molded object, material set for three-dimensional molding, and hydrogel precursor liquid
US20190168016A1 (en) 2016-02-09 2019-06-06 Luma Therapeutics, Inc. Methods, compositions and apparatuses for treating psoriasis by phototherapy
US11534527B2 (en) 2016-05-03 2022-12-27 T & R Biofab Co., Ltd. Method for supplying inks for three-dimensional printing, and three-dimensional printing method using same
WO2017192004A1 (ko) * 2016-05-03 2017-11-09 주식회사 티앤알바이오팹 삼차원 프린팅용 잉크를 공급하는 방법 및 이를 이용한 삼차원 프린팅 방법
US10926454B2 (en) * 2016-05-20 2021-02-23 Sartorius Stedim Biotech Gmbh Dispensing device and system for biological products
GB201609764D0 (en) * 2016-06-03 2016-07-20 Isis Innovation 3D printing of gel networks
CN109803691A (zh) * 2016-06-16 2019-05-24 安斯百克特生物系统公司 生物打印的半月板植入物及其使用方法
EP3482260B1 (en) 2016-07-08 2023-08-30 Cypre, Inc. Apparatus for patterning hydrogels into multi-well plates
WO2018013727A1 (en) 2016-07-12 2018-01-18 Deka Products Limited Partnership System and method for applying force to a device
USD812766S1 (en) * 2016-07-12 2018-03-13 EMULATE, Inc. Microfluidic chip for use with a fluid perfusion module
US11254901B2 (en) 2016-07-12 2022-02-22 Deka Products Limited Partnership System and method for printing tissue
EP3490801B1 (en) * 2016-07-27 2021-06-30 President and Fellows of Harvard College Apparatus and method for acoustophoretic printing
US20180056586A1 (en) * 2016-08-26 2018-03-01 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Tailored Multi-Material Delivery for Direct-Write Manufacturing
USD816861S1 (en) * 2016-09-07 2018-05-01 EMULATE, Inc. Transparent microfluidic chip without pressure features for use with a fluid perfusion module
USD842493S1 (en) * 2016-09-07 2019-03-05 EMULATE, Inc. Microfluidic chip without pressure features for use with a fluid perfusion module
US11299705B2 (en) 2016-11-07 2022-04-12 Deka Products Limited Partnership System and method for creating tissue
US11969935B2 (en) * 2016-12-07 2024-04-30 President And Fellows Of Harvard College Valved nozzle with a compensator and massively parallel 3D printing system
DE102016225227B4 (de) * 2016-12-16 2025-04-30 Robert Bosch Gmbh Verfahren zum additiven Fertigen eines dreidimensionalen Objekts
CN106510898A (zh) * 2016-12-21 2017-03-22 中国人民大学 一种基于多通道喷嘴的多组分三维生物打印装置和方法
JP6861408B2 (ja) 2016-12-27 2021-04-21 東京応化工業株式会社 細胞培養用チップの製造方法
EP3595872A4 (en) * 2017-03-15 2021-05-05 Aspect Biosystems Ltd. SYSTEMS AND METHODS FOR PRINTING A FIBROUS STRUCTURE
CN106926456B (zh) * 2017-04-22 2018-12-28 广东工业大学 一种支架充液辅助成型系统
KR102611274B1 (ko) 2017-05-11 2023-12-07 킹 압둘라 유니버시티 오브 사이언스 앤드 테크놀로지 조직 가공 및 바이오프린팅 시 사용하기 위한 겔을 형성할 수 있는 펩타이드
EP4215600A1 (en) * 2017-05-11 2023-07-26 King Abdullah University of Science and Technology Device and method for microfluidics-based 3d bioprinting
CN110621347A (zh) 2017-05-12 2019-12-27 康宁股份有限公司 用于3d生物打印和药物递送的具有可调流变学的交联的剪切稀化流体
CA3063847A1 (en) 2017-05-16 2018-11-22 Embody Inc. Biopolymer compositions, scaffolds and devices
US12619211B2 (en) 2017-06-06 2026-05-05 Organofab Technologies, Inc. Method and apparatus for a tissue engineering system utilizing stacked layers
US11048230B2 (en) 2017-06-06 2021-06-29 Organofab Technologies, Inc. Method and apparatus for a tissue engineering system
GB201710834D0 (en) 2017-07-05 2017-08-16 Univ Newcastle Printing apparatus and method
US10570362B2 (en) 2017-07-12 2020-02-25 Deka Products Limited Partnership System and method for transferring tissue
US12297416B2 (en) 2017-07-12 2025-05-13 Deka Products Limited Partneship System and method for transferring tissue
FR3069806B1 (fr) * 2017-08-03 2019-08-23 Centre National De La Recherche Scientifique Tete d'impression d'une imprimante, imprimante et procede d'impression
JP7529567B2 (ja) 2017-10-24 2024-08-06 エムボディ インコーポレイテッド 生体高分子足場移植片およびその生成のための方法
US10967576B2 (en) 2017-11-10 2021-04-06 Local Motors IP, LLC Additive manufactured structure having a plurality of layers in a stacking direction and method for making the same
CA3086602A1 (en) * 2017-12-08 2019-06-13 Inventia Life Science Pty Ltd Bioprinter for fabricating 3d cell constructs
US12029834B2 (en) 2017-12-20 2024-07-09 Aspect Biosystems Ltd. Bioprinted meniscus implant and methods of using same
US10350822B1 (en) * 2018-01-09 2019-07-16 Triastek Inc. Dosage forms with desired release profiles and methods of designing and making thereof
SE1850073A1 (en) * 2018-01-24 2019-07-25 Cellink Ab 3D bioprinters
CN110339469A (zh) * 2018-04-08 2019-10-18 上海叁钛生物科技有限公司 皮肤原位打印用打印头装置
JP2022501209A (ja) 2018-04-23 2022-01-06 ローカル モーターズ アイピー, エルエルシーLocal Motors Ip, Llc 付加製造のための方法及び装置
US11731342B2 (en) 2018-04-23 2023-08-22 Rapidflight Holdings, Llc Additively manufactured structure and method for making the same
DE102018111751A1 (de) * 2018-05-16 2019-11-21 Cellbricks Gmbh Verfahren zur Herstellung eines Zellkultureinsatzes mit mindestens einer Membran
GB201810447D0 (en) * 2018-06-26 2018-08-08 Univ Leuven Kath Photopolymerised cell culture devices
EP3853003B1 (en) 2018-09-19 2026-07-22 Aspect Biosystems Ltd. Systems and methods for printing a core fiber
CA3122120A1 (en) * 2018-12-06 2020-06-11 Inventia Life Science Pty Ltd Printhead assembly for a 3d bioprinter
JP7686561B2 (ja) 2019-02-01 2025-06-02 エンボディ，インコーポレイテッド マイクロフルイディック押出
WO2020204895A1 (en) 2019-03-29 2020-10-08 Hewlett-Packard Development Company, L.P. Generating fluidic components
US20220212192A1 (en) * 2019-06-01 2022-07-07 Northeastern University Microfluidic Device for High-Throughput Screening of Tumor Cell Adhesion and Motility
WO2021029868A1 (en) * 2019-08-12 2021-02-18 Local Motors IP, LLC Additively manufactured structure and method for making the same
US11813790B2 (en) 2019-08-12 2023-11-14 Rapidflight Holdings, Llc Additively manufactured structure and method for making the same
US11083830B2 (en) 2019-10-14 2021-08-10 Fresenius Medical Care Holdings, Inc. Implantable fluid conduit
WO2021079192A1 (en) * 2019-10-21 2021-04-29 Fluicell Ab Methods and systems for generating three-dimensional biological structures
EP4051487A4 (en) * 2019-11-01 2023-11-22 Aspect Biosystems Ltd. SYSTEMS AND METHODS FOR PRINTING A CORE-SHELL FIBER
KR102210626B1 (ko) * 2020-02-28 2021-02-02 (주)케이랩스 공기압을 이용한 3d 프린팅 장치
ES3000067T3 (en) * 2020-06-25 2025-02-27 Dloc Biosystems Inc Method of manufacture a biochip
AT523819B1 (de) * 2020-07-03 2021-12-15 Charlotte Ohonin Kultivierungsvorrichtung für ein Kulitivieren von Zellkulturen
EP3932437A1 (en) * 2020-07-03 2022-01-05 Fundació Institut de Bioenginyeria de Catalunya (IBEC) Printing system for obtaining biological fibers
WO2022038552A1 (en) * 2020-08-20 2022-02-24 King Adbullah University Of Science And Technology Nozzle for 3d bioprinting
US11673324B2 (en) 2020-08-20 2023-06-13 King Abdullah University Of Science And Technology Nozzle for 3D bioprinting
US12590121B2 (en) 2020-08-20 2026-03-31 King Abdullah University Of Science And Technology Peptide compound with repetitive sequences
US12109327B2 (en) 2020-08-20 2024-10-08 King Abdullah University Of Science And Technology Scaffolds from self-assembling tetrapeptides support 3D spreading, osteogenic differentiation and angiogenesis of mesenchymal stem cells
EP4208471A4 (en) 2020-09-02 2024-10-09 King Abdullah University Of Science And Technology DOPA-CONTAINING PEPTIDE-BASED ADHESIVE GELS
BR102020018170A2 (pt) * 2020-09-04 2022-03-22 Tissuelabs Pesquisa E Desenvolvimento Ltda Sistema de bioimpressão 3d, adaptador de seringa, uso de um sistema de bioimpressão 3d e processo de extrusão
WO2022084874A1 (en) * 2020-10-21 2022-04-28 King Adbullah University Of Science And Technology Delivery of endothelial cell-laden microgel elicits angiogenesis in self-assembling ultrashort peptide hydrogels
US11994520B2 (en) 2020-11-23 2024-05-28 King Abdullah University Of Science And Technology Developing lateral flow immunochromatography (LFIA) peptide-based test strips for rapid detection of antigens and antibodies against specific antigens
CN112549532A (zh) * 2020-12-08 2021-03-26 南通大学 一种基于3d打印装置的微流控芯片制备方法
WO2022134912A1 (zh) * 2020-12-25 2022-06-30 湖州艾先特电子科技有限公司 一种适用于3d生物打印机上料的搅拌机构
US11628600B2 (en) 2021-05-21 2023-04-18 Saudi Arabian Oil Company Fabrication method of transparent 3D polydimethylsiloxane devices with polycaprolactone molds
CN113500773B (zh) * 2021-07-08 2022-04-01 吉林大学 仿龙虾眼聚焦脉冲强光原位成型4d打印装置及方法
KR102742210B1 (ko) * 2021-08-31 2024-12-16 고려대학교 세종산학협력단 3차원 공압 액추에이터가 통합된 오리피스 가변형 마이크로 액적 생성기 및 그의 제조 방법
CN118695938A (zh) * 2021-12-16 2024-09-24 安斯百克特生物系统公司 径向泵组合件及其使用方法
WO2023248105A1 (en) 2022-06-21 2023-12-28 King Abdullah University Of Science And Technology Mussel-inspired photoreactive instant glue for
EP4558272A4 (en) * 2022-07-21 2026-07-22 Abs Global Inc SYSTEMS, METHODS AND APPARATUS FOR A MICROFLUIDIC CHIP HAVING A MICROCHANNEL DESIGN THAT ASYMMETRICALLY FOCUSES PARTICLES
WO2025160474A1 (en) * 2024-01-25 2025-07-31 Carnegie Mellon University 3d bioprinted hydrogel microfluidic systems and perfusion bioreactors for engineering vascularized tissue constructs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080206383A1 (en) 2007-01-17 2008-08-28 Hull Charles W Solid Imaging System with Removal of Excess Uncured Build Material
US20120089238A1 (en) 2010-10-06 2012-04-12 Hyun-Wook Kang Integrated organ and tissue printing methods, system and apparatus
US20120322154A1 (en) 2011-06-15 2012-12-20 Korea Institute Of Machinery & Materials Apparatus and method for manufacturing cell culture scaffold

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292472A (en) 1992-12-18 1994-03-08 Bridgestone Corporation Coextrusion apparatus and method with rotating cord guidance
US7033603B2 (en) 1999-08-06 2006-04-25 Board Of Regents The University Of Texas Drug releasing biodegradable fiber for delivery of therapeutics
US7051654B2 (en) 2003-05-30 2006-05-30 Clemson University Ink-jet printing of viable cells
US8639484B2 (en) 2003-11-14 2014-01-28 Drexel University Method and apparatus for computer-aided tissue engineering for modeling, design and freeform fabrication of tissue scaffolds, constructs, and devices
US8241905B2 (en) 2004-02-24 2012-08-14 The Curators Of The University Of Missouri Self-assembling cell aggregates and methods of making engineered tissue using the same
US7939003B2 (en) 2004-08-11 2011-05-10 Cornell Research Foundation, Inc. Modular fabrication systems and methods
US9427496B2 (en) 2005-02-18 2016-08-30 Drexel University Method for creating an internal transport system within tissue scaffolds using computer-aided tissue engineering
US8398935B2 (en) 2005-06-09 2013-03-19 The United States Of America, As Represented By The Secretary Of The Navy Sheath flow device and method
EP1790861A1 (en) 2005-11-25 2007-05-30 Bonsens AB Microfluidic system
JP2008017798A (ja) 2006-07-14 2008-01-31 Olympus Corp 生体組織製造装置および生体組織製造方法
US8047235B2 (en) * 2006-11-30 2011-11-01 Alcatel Lucent Fluid-permeable body having a superhydrophobic surface
US20100278798A1 (en) 2007-09-27 2010-11-04 The Trustees Of Columbia University In The City Of New York Methods and systems for forming biocompatible materials
GB0722092D0 (en) 2007-11-09 2007-12-19 Q Chip Ltd Microfluidic device and method for producing sheathed flow
SG188832A1 (en) 2008-02-29 2013-04-30 Agency Science Tech & Res Hydrodynamic spinning of polymer fiber in coaxial laminar flows
EP2127747A1 (en) 2008-05-20 2009-12-02 F.Hoffmann-La Roche Ag Microfluid analytical device comprising a valve with swellable material
KR101004769B1 (ko) 2008-09-09 2011-01-04 서울대학교산학협력단 광유체적 리소그래피 시스템 및 마이크로구조물 제조방법
CN102239248B (zh) 2008-12-02 2013-10-30 皇家飞利浦电子股份有限公司 同轴封装的细胞悬浮液和微组织
US20110136162A1 (en) 2009-08-31 2011-06-09 Drexel University Compositions and Methods for Functionalized Patterning of Tissue Engineering Substrates Including Bioprinting Cell-Laden Constructs for Multicompartment Tissue Chambers
WO2011046105A1 (ja) 2009-10-14 2011-04-21 国立大学法人 東京大学 被覆されたマイクロゲルファイバ
RU2573409C2 (ru) 2009-11-04 2016-01-20 Дзе Юниверсити Оф Бритиш Коламбиа Содержащие нуклеиновые кислоты липидные частицы и относящиеся к ним способы
US9174390B2 (en) * 2009-12-30 2015-11-03 DePuy Synthes Products, Inc. Integrated multi-material implants and methods of manufacture
US9090868B2 (en) 2010-07-12 2015-07-28 President And Fellows Of Harvard College Alginate hydrogel fibers and related materials
RU2560393C2 (ru) 2010-10-21 2015-08-20 Органово, Инк. Устройства, системы и способы изготовления ткани
KR101222890B1 (ko) * 2010-11-24 2013-01-17 고려대학교 산학협력단 표면 장력을 이용한 마이크로 밸브 및 이를 포함하는 미세유체칩, 및 이의 제조방법
CN103402639A (zh) 2010-12-06 2013-11-20 南澳大利亚大学 高处理能力微流装置
CN102309782B (zh) 2011-09-02 2013-10-16 西安交通大学 一种基于活细胞的复杂三维微通道多孔支架的制备方法
US9499779B2 (en) 2012-04-20 2016-11-22 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking
US20140232035A1 (en) * 2013-02-19 2014-08-21 Hemant Bheda Reinforced fused-deposition modeling
US9579851B2 (en) * 2013-03-22 2017-02-28 Markforged, Inc. Apparatus for fiber reinforced additive manufacturing
PT3670155T (pt) 2013-06-13 2025-07-08 Aspect Biosystems Ltd Cabeça de impressão, sistema de fabrico aditivo de estruturas tridimensionais e respetivo método
EP3065875A4 (en) 2013-11-04 2018-02-07 University of Iowa Research Foundation Bioprinter and methods of using same
EP3970945A1 (en) 2013-11-19 2022-03-23 Guill Tool & Engineering Filament for use in a 3d printer and method for producing the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080206383A1 (en) 2007-01-17 2008-08-28 Hull Charles W Solid Imaging System with Removal of Excess Uncured Build Material
US20120089238A1 (en) 2010-10-06 2012-04-12 Hyun-Wook Kang Integrated organ and tissue printing methods, system and apparatus
US20120322154A1 (en) 2011-06-15 2012-12-20 Korea Institute Of Machinery & Materials Apparatus and method for manufacturing cell culture scaffold

Also Published As

Publication number Publication date
EP4628285A2 (en) 2025-10-08
CA2915737C (en) 2016-09-13
US20160136895A1 (en) 2016-05-19
DK3007882T3 (da) 2020-02-24
IL243014B (en) 2019-08-29
AU2014280825B2 (en) 2018-01-04
KR20210097816A (ko) 2021-08-09
WO2014197999A1 (en) 2014-12-18
US20240190065A1 (en) 2024-06-13
DK3670155T3 (da) 2025-07-21
JP2019201644A (ja) 2019-11-28
JP2016530874A (ja) 2016-10-06
US11738501B2 (en) 2023-08-29
JP2024124406A (ja) 2024-09-12
US20210317404A1 (en) 2021-10-14
RU2643138C2 (ru) 2018-01-30
EP3670155B1 (en) 2025-04-30
EP3007882B1 (en) 2019-11-20
EP3007882A4 (en) 2017-03-22
CN105579219A (zh) 2016-05-11
JP6733014B2 (ja) 2020-07-29
JP6550379B2 (ja) 2019-07-24
US20260233457A1 (en) 2026-08-13
FI3670155T3 (fi) 2025-07-17
ES3035595T3 (en) 2025-09-05
RU2016100442A (ru) 2017-07-18
PT3670155T (pt) 2025-07-08
JP7217248B2 (ja) 2023-02-02
BR112015031320B1 (pt) 2022-01-18
EP3007882A1 (en) 2016-04-20
ES2770418T3 (es) 2020-07-01
SG11201510138RA (en) 2016-01-28
PL3670155T3 (pl) 2025-09-01
US11046930B2 (en) 2021-06-29
JP7498318B2 (ja) 2024-06-11
KR20160030939A (ko) 2016-03-21
JP2023061953A (ja) 2023-05-02
PT3007882T (pt) 2020-02-20
CA2915737A1 (en) 2014-12-18
AU2014280825A1 (en) 2016-01-28
EP4628285A3 (en) 2026-01-14
BR112015031320A2 (pt) 2017-07-25
JP2020182474A (ja) 2020-11-12
PL3007882T3 (pl) 2020-06-01
CN105579219B (zh) 2017-09-01
US12441050B2 (en) 2025-10-14
JP7897893B2 (ja) 2026-07-30
EP3670155A1 (en) 2020-06-24
KR102284531B1 (ko) 2021-08-03

Similar Documents

Publication Publication Date Title
KR102284531B1 (ko) 3차원 구조물의 첨삭 가공을 위한 장치 및 방법
CN111372785B (zh) 印刷机的印刷头部、印刷机和印刷方法
Gupta et al. Droplet-based bioprinting
WO2017049066A1 (en) Apparatus for culturing and interacting with a three-dimensional cell culture
CN109760311B (zh) 一种具有整合系统的3d生物打印机
CN113365799B (zh) 用于打印芯纤维的系统和方法
JP5999646B2 (ja) 自動細胞ハンドリングロボットにおける泡沫除去デバイス
CN106237944B (zh) 核壳结构制备方法和核壳结构制备设备
US12012578B2 (en) Cell printing utilizing recirculating fluid flows
Petronaitis Design, realization, and validation of an extrusion-based bioprinter for hydrogel applications on microchips
Schneider Generation, probing, and biophysical stimulation of human microtissues in microfluidic Organ-on-Chip platforms

Legal Events

Date Code Title Description
A107 Divisional application of patent
PA0104 Divisional application for international application

St.27 status event code: A-0-1-A10-A18-div-PA0104

St.27 status event code: A-0-1-A10-A16-div-PA0104

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-OTH-PR1001 (AS PROVIDED BY THE NATIONAL OFFICE)

Year of fee payment: 4