KR102411634B1 - Health functional food composition for improvement of bowel function and relief of contipation comprising psyllium husk and complex extract, and manufacturing method thereof - Google Patents

Abstract

The present invention relates to a health functional food composition for improving intestinal function and facilitating defecation, comprising psyllium hull and complex extract, and a method for manufacturing the same, and the health functional food composition of the present invention comprises defecation frequency, defecation degree, defecation pain, gas generation, Since it can improve the symptoms related to bowel function and defecation, such as feeling of small bowel movements and abdominal distension, it can be usefully used for improving intestinal function and facilitating defecation.

Description

Health functional food composition for improving intestinal function and facilitating bowel movement, including psyllium hull and complex extract, and manufacturing method thereof

The present invention relates to a health functional food composition for improving intestinal function and promoting bowel movements, comprising psyllium hull and complex extract, and a method for preparing the same.

Modern people's physical activity has decreased due to longer working hours, advanced transportation, and improved living standards, while their diet has become westernized and instantiated, increasing calorie intake and decreasing fiber intake. As a result, metabolic diseases, which have been frequently occurring in the West, are gradually increasing in Korea, and in particular, more and more people with constipation, which are well known in clinical practice.

In general, it is a normal state for food to be excreted 12-72 hours after ingestion of food depleted of nutrients. However, for some reason, it cannot be discharged to the outside of the body, and there are cases where it stays in the intestine for a long time, which is called constipation.

Constipation is more of a symptom than a disease, and it appears as a variety of symptoms and diseases. The most common symptoms include decreased frequency of bowel movements (e.g., less than 3 times per week), irregular bowel movements, painful and difficult bowel movements, hard, dry bowel movements, and a feeling of small bowel movements (e.g., an unusually small amount of bowel movements per day). 50 g or less) are common.

Medically, constipation is defined as a bowel movement less than once every 3-4 days by emphasizing the frequent or difficult bowel movements.

Constipation may result from intestinal obstruction or flow obstruction, anus and pelvic abnormalities, neurological disorders, metabolic or hormonal disorders, adverse drug reactions, and dehydration or immobilization. Constipation can occur for no specific reason (chronic constipation), lack of exercise, neglect of bowel movements, low fiber intake, irregular lifestyle (e.g., long-distance travel or hospitalization) or personal factors (Bosaeus, 2004).

Conventionally, various bowel-stimulating drugs, functional foods, etc. have been used for the improvement or treatment of constipation, but the effect is insignificant or in most cases temporary, so it is difficult to see that constipation can be fundamentally treated.

Therefore, there is a need to develop a functional food composition for improving intestinal function and promoting bowel movements using natural materials that are harmless to the human body.

Republic of Korea Patent Publication No. 10-1450968

The present inventors recognize the problems of the prior art, and when a health functional food composition containing a specific extract is taken, bowel function and defecation related phenomena such as bowel movement frequency, bowel change degree, bowel pain, gas generation, feeling of leftovers, and abdominal distension By showing the effect of improving it, it was proved that it can be usefully used for improving intestinal function and promoting bowel movements, and led to the completion of the present invention.

The present invention is psyllium; And it relates to a food composition for improving intestinal function and facilitating bowel movement, including; and complex extracts of kelp, eoseongcho, tungtungnodi, cornflower oil, licorice and gilkyung.

The present invention relates to a method for preparing a health functional food composition for improving intestinal function and promoting bowel movements.

Hereinafter, this will be described in detail. All combinations of the various elements disclosed herein are within the scope of the present invention. In addition, it cannot be considered that the scope of the present invention is limited by the following specific description.

The present invention is psyllium; It provides a food composition for improving intestinal function and promoting bowel movements, including; and a complex extract of kelp, eoseongcho, tungtungnodji, cornflower oil, licorice and gilkyung.

In the present invention, "Psyllium husk" is obtained by extracting, separating, and refining the skin of psyllium, which is a mature seed of a perennial herbaceous plantain (Plantago asiatica) belonging to the Plantaginaceae family, well known in the art. Or it refers to a reagent in the form of a commercially available powder. Psyllium is mainly produced in India, which accounts for about 80% of the world's production. In oriental medicine, psyllium has been widely used for nephritis, cystitis, and urethritis as a powerful diuretic, and contains a lot of minerals, proteins, vitamins, and polysaccharides. have.

In the present invention, "kelp (Laminaria japonica)" refers to large perennial brown algae belonging to the family Laminariaceae, also referred to as Phaeophyceae, seaweed, or sea kelp. In appearance, it is divided into a leaf, a stem, and a root. It is a cold-planet seaweed distributed in the cold and boreal coasts, and grows wild in North Hamgyong Province north of Wonsan and the northern part of the east coast in Korea. The kelp has been widely used for food or medicine in Japan and China including Korea since ancient times.

In the present invention, "Houttuynia cortata" is called a fish-smelling grass since ancient times. Eoseongcho is known to have anti-inflammatory, anti-dementia, and Parkinson's effects because it is effective for skin diseases, has anti-viral effects, and has excellent antioxidant effects. It is also being developed as a cosmetic for improving acne. It has been reported that such eoseongcho contains a lot of flavonoid components.

In the present invention, "Tungtung nodule" is an annual herbaceous plant belonging to the family Chrysanthemum, has strong salt resistance among halophytes, and is an absolute halophyte that absolutely requires salt for growth. Tongtung nodule contains a large amount of plant salts (NaCl, KCl, etc.) in the body, calcium, magnesium, potassium, etc., and is also rich in nutrients such as a large amount of dietary fiber, essential amino acids, and plant physiologically active substances such as chlorophyll, polyphenol, and flavonoids. It has been used as a folk remedy to remove toxins and sukbyeon accumulated in the body, and to treat cancer, high blood pressure, diabetes, hepatitis, skin diseases, and arthritis.

In the present invention, "cornus officinalis" means a deciduous small tree belonging to the Dogwood family cultivated throughout Korea and other tropical to temperate regions, and includes various varieties and subspecies. Cornin, morroniside, which stimulates parasympathetic nerves, and loganin, tannin, and saponin, which have a slight central nervous system excitatory action, and glycosides It contains a large amount of tannin and vitamin A, which are astringent components, and is effective in nourishing and astringent, and has functional ingredients such as selenium that can prevent cancer. In addition, it contains vitamin A and a large amount of sugar.

In the present invention, cornus oil may be used for pulp, leaves, stems, seeds and/or roots, and according to embodiments of the present invention, preferably fruits.

In the present invention, "Licorice" refers to a perennial plant belonging to the legume family distributed in northeastern China, Siberia, Mongolia, and northern China. Licorice root and the lower part of the stem can be used as a sweetener and as a treatment for gastric and duodenal ulcers, and since it softens the action of other drugs, it is also used for various purposes in oriental medicine. In general, licorice contains glycyrrhizin, glabriic acid, sucrose, glucose, liqueuritin, licoricidin, and the like, and glycyrrhizin has the effect of detoxifying diphtheria toxin, snake venom, and pufferfish venom, so it is also used as a treatment for tetanus.

In the present invention, "gilgyeong (Platycodon root)" is also referred to as bellflower, and is a perennial plant of the Bellflower family, commonly grown in mountains or fields, has a height of 40 to 100 centimeters, has a thick root, and has a single stem. . Gilgyeong has been used as a medicine for neuralgia and tonsillitis, and is also used as an expectorant, antitussive, analgesic, sedative, and antipyretic.

The psyllium hull, kelp, eoseongcho, tungtungknife, cornflower oil, licorice, and gilgyeong used as raw materials in the present invention can be used without limitation, those collected from nature, directly grown, or commercially available (including processed ones).

In the present invention, "extract" means the result of extraction using an appropriate extraction solvent and extraction method. purified products, or fractions.

In the present invention, "complex extract" refers to an extract extracted through a certain manufacturing process in a mixture state in which the raw materials of each extract are mixed at the same time.

According to embodiments of the present invention, the raw materials for preparing the complex extract may be in a state in which kelp, eoseongcho, tungtungnodi, cornflower oil, licorice and gilgyeong are crushed and evenly mixed.

According to embodiments of the present invention, the complex extract may be extracted from a raw material mixture obtained by mixing kelp, eoseongcho, tungtungknife, cornflower oil, licorice and gilgyeong in a weight ratio of 1:1:1:1:1:1, , the weight ratio may be for showing an excellent effect by the active ingredient of the complex extract.

According to the embodiments of the present invention, the health functional food composition may include the psyllium hull and the complex extract in a weight ratio of 1:1, and the weight ratio shows an excellent effect by the active ingredient of the health functional food composition. it may be for

In the present invention, "active ingredient" means a component that can exhibit the desired activity (effect) alone or with a carrier that has no activity by itself, and can be used interchangeably with the active ingredient in the present specification. .

The complex extract of kelp, eoseongcho, tungtungknife, cornflower oil, licorice and gilkyung contained in the health functional food composition of the present invention is extracted and mixed by a specific manufacturing method, thereby improving intestinal function and facilitating bowel movement.

In the present invention, the complex extract may be extracted by a method comprising the following steps:

S1) pulverizing the raw material mixture of kelp, eoseongcho, tungtungknife, cornus oil, licorice and gilkyung, and adding 80% (w/v) ethanol to the pulverized raw material mixture, followed by stirring to homogenize;

S2) ultrasonically extracting the homogenized raw material mixture solution by ultrasonication at 60 to 80° C. for 2 to 4 hours;

S3) separating the sonicated solution into a filtrate and a residue by filtering;

S4) adding purified water to the separated residue, followed by stirring to homogenize;

S5) heat-treating the homogenized solution at 130 to 150° C. for 2 to 4 hours to extract hot water;

S6) filtering the heat-treated solution to separate it into a filtrate and a residue; and

S7) mixing the filtrate separated in steps S3 and S6.

Hereinafter, each step of the complex extract manufacturing method will be described in detail.

The step S1 in the complex extract manufacturing method of the present invention is a step of preparing a raw material mixture solution by grinding the raw material mixture, adding a solvent, and stirring and homogenizing.

In step S1, the solvent is preferably 80% (w/v) ethanol for ultrasonic extraction to be performed following step S1, and when purified water is used, the yield of the active ingredient to be extracted may be low.

In step S1, the raw material mixture may be in a frozen state. That is, in step S1 of the present invention, the raw material mixture may be prepared in a frozen state and pulverized through a grinder.

The pulverization of step S1 may be performed to have a size of 10 to 500 μm, and preferably may be performed to have a size of 400 to 500 μm.

When pulverized to a size smaller than the above range, time and energy efficiency may be reduced in the process of pulverizing the raw material mixture in a frozen state, and when pulverized larger than the above range, the active ingredient contained in the raw material mixture is sufficiently extracted Therefore, it may not be able to sufficiently exhibit the intended effect of the present invention.

In addition, the raw material mixture in step S1 may be subjected to a pretreatment step including the following steps before pulverization:

a) washing and mixing kelp, eoseongcho, tungtungnodri, cornflower oil, licorice and gilgyeong, adding purified water, leaving it for 10 to 20 minutes, and then removing the water;

b) freezing the water-removed mixture at -40 to -50°C and then leaving it at room temperature for 3 to 4 hours; and

c) Freezing the left mixture at -40 to -50°C after drying.

The shredding in step a) may be performed so that the size of the raw material is 0.1 to 1.0 cm, and preferably 0.3 to 0.7 cm. According to embodiments of the present invention, the slicing may be performed to be about 0.5 cm, but is not limited thereto.

Step a) is to immerse (permeate) the purified water into each raw material, and it is sufficient to leave it for a time for the purified water to be sufficiently absorbed into the raw material mixture, but it may be preferable to leave it for 10 to 20 minutes for manufacturing efficiency. have.

"Remove water" in step a) means removing the purified water existing outside the mixture, for example, it may be to remove the purified water existing outside the mixture and the mixture by passing through a filter, but is not limited thereto it is not In addition, it may mean to remove 90% to 99.9%, preferably 95% to 99.9% of purified water existing outside the mixture, but is not limited thereto.

Step b) is a step of performing freezing and thawing on the raw material mixture immersed in purified water, and according to embodiments of the present invention, step b) is repeated three or more times, and it may be preferable to be continuously performed, , more preferably 3 to 5 times, more preferably 4 or 5 times, and may be continuously performed, but is not limited thereto.

When it is carried out a number of times less than the above range, the effect of increasing the extraction of the active ingredient due to the pretreatment may be insignificant, and when it is performed more times than the range, the effect of increasing the extraction of the active ingredient compared to time and energy consumption may not be large. It is not suitable for manufacturing efficiency.

In the experimental example to be described later, when step b) is repeatedly performed three or more times, it has been specifically demonstrated that the effect of improving intestinal function and promoting bowel movement can be greatly improved. It was confirmed that the extraction yield of

In the method for producing a complex extract of the present invention, step S2 is a step of ultrasonically extracting the homogenized raw material mixture solution.

The step S2 is carried out at 60 to 80 ℃, below the temperature range, extraction of the components included in the raw material mixture may not sufficiently occur, and if it exceeds the above range, the extraction yield may increase and the extraction time may be shortened. , there is a problem that the active ingredient contained in the raw material mixture may be denatured by heat. Therefore, in consideration of both the extraction yield and integrity of the active ingredient, the temperature in the above range is very advantageous.

Step S2 may be performed for 2 to 4 hours, and according to embodiments of the present invention, may be performed for about 3 hours, but is not limited thereto.

If the extraction is less than the time range, the extraction of the active ingredient contained in the raw material mixture may not sufficiently occur, and if it exceeds the above range, the extraction yield of the active ingredient relative to the time may be lowered, which may not be appropriate in terms of manufacturing efficiency.

In addition, when the ultrasonic extractor is irradiated with a focus on a specific position, the temperature of the medium may rise and the active ingredient contained in the raw material may be destroyed or denatured. In addition, the stirring may be performed by a stirring device provided in the ultrasonic irradiation device, or may be performed through a separately provided stirring device.

In the method for producing a complex extract of the present invention, steps S3 and S6 are steps of separating the residue and the filtrate containing the active material by ultrasonic extraction, and the separation may be performed by a known method.

In the method for manufacturing a complex extract of the present invention, steps S4 and S5 are steps of hot water extraction of the residue remaining after separation in step S3.

In step S5, the solvent is preferably purified water, and when an organic solvent is used, the yield of the active ingredient to be extracted remaining in the residue may be lowered.

The step S5 may be performed at 130 to 150° C., and may be performed for 2 to 4 hours.

Below the temperature range, extraction of the components contained in the residue may not sufficiently occur, and if it exceeds the above range, the extraction yield may be increased and the extraction time may be shortened, but the active ingredient contained in the residue may be denatured by heat The problem is that it could be. Therefore, in consideration of both the extraction yield and integrity of the active ingredient, the temperature in the above range is very advantageous.

In addition, if the extraction is less than the time range, the extraction of the active ingredient contained in the residue may not sufficiently occur, and if it exceeds the above range, the extraction yield of the active ingredient relative to the time may be lowered, which may not be appropriate in terms of manufacturing efficiency. have.

Between the steps S2 and S3 in the complex extract manufacturing method of the present invention; And cooling the extract obtained between steps S5 and S6 to 2 to 6 ℃, and may further include the step of leaving (aged) for 4 to 6 hours, thereby improving intestinal function and defecation with the extracted active ingredient It may exhibit the effect of increasing the accelerating effect.

In the complex extract manufacturing method of the present invention, step S7 is a step of mixing the filtrate separated in steps S3 and S6, and the component maximally extracted from the raw material by a manufacturing method in which different extraction methods are continuously and sequentially performed. is a mixing step.

In the method for manufacturing the complex extract of the present invention, it may be advantageous to perform steps S1 to S7 continuously and sequentially in maximally extracting the active ingredient from the raw material. In this case, it was specifically demonstrated that the effect of improving intestinal function and promoting bowel movements can be increased.

In the present invention, the composition may further include mixed lactic acid bacteria.

The mixed lactic acid bacteria is Lactobacillus acidophilus (Lactobacillus acidophilus), Lactobacillus bifidus (Lactobacillus bifidus), Lactobacillus acidophilus (lactobacilus acidophilus), Streptococcus faecalis (Streptococcus faecalis), Streptococcus faecium (Streptococcus faecalis), Streptococcus , Bacillus subtilis, Bacillus licheniformis, Bacillus polyfermenticus, Bacillus mesentericus, Saccharomyces cerevisiae, At least one selected from the group consisting of Clostridium butyricum, Pediococcus pentosaceus, Enterococcus faecium and Bifidobacterium longum However, it is not limited thereto, and any lactic acid bacteria known to have an effect of improving intestinal function and promoting bowel movements may be used.

In the present invention, "health functional food" refers to a food manufactured using raw materials or ingredients that are easily deficient in daily meals or have a useful function in the human body, and refers to food that helps maintain human health, but is limited thereto. This includes all health foods in the ordinary sense.

In the present invention, the health functional food may be mixed with food additives in the form of tablets, capsules, pills, granules, liquids, powders, flakes, syrups, gels, jellies, bars, films, etc. to be commercialized as health functional food.

Food additives that can be mixed in the health functional food include, for example, flavoring agents, sweeteners, flavoring agents, preservatives, natural carbohydrates, nutrients, vitamins, electrolytes, colorants, pextan and salts thereof, alginic acid and salts thereof, It may be an organic acid, a protective colloidal thickener, a pH adjuster, a stabilizer, a preservative, glycerin, alcohol, and the like, but is not limited thereto. may be included without limitation.

In addition, the health functional food composition of the present invention is already safe in the art, in addition to the active ingredient, in order to improve the intestinal function and enhance the effect of facilitating bowel movement, in order to enhance the convenience of taking or intake through the addition of similar activity. It may further include any compound or natural extract that has been tested and is known to have a given activity. Such compounds or extracts include compounds, extracts, and pharmaceuticals listed in compendial documents such as pharmacopeias of each country (“Korea Pharmacopoeia” in Korea) and health functional food regulations of each country (“health functional food standards and specifications” announced by the Ministry of Food and Drug Safety in Korea). Each country's laws governing the manufacture and sale of compounds or extracts and health functional foods that have been approved for items in accordance with the laws of each country (the "Pharmaceuticals Act" in Korea) governing the manufacture and sale of '), and compounds or extracts whose functionality is recognized are included.

Another aspect of the present invention is psyllium; and a complex extract of kelp, eoseongcho, tungtungnodi, cornflower oil, licorice and gilkyung; provides a method for manufacturing a health functional food for improving intestinal function and promoting bowel movements, including.

Unless otherwise stated, in the method for manufacturing health functional food for improving intestinal function and facilitating bowel movement of the present invention, it is the same as described for the health functional food composition for improving intestinal function and facilitating bowel movement, and in order to avoid excessive repetition of the specification, the description is omit

Since the health functional food composition of the present invention can improve bowel function and defecation-related phenomena such as bowel movement frequency, bowel change degree, bowel pain, gas generation, residual bowel movements, and abdominal distension, it can be usefully used for improving bowel function and facilitating defecation. can

In addition, since the health functional food composition for improving intestinal function and facilitating bowel movement of the present invention contains active ingredients extracted from various natural raw materials, it is possible to enjoy the useful effects of the raw materials together.

In addition, since the health functional food composition for improving intestinal function and facilitating bowel movement of the present invention has a high degree of preference for taste and smell, it can be taken for a long period of time, so it can be easily used to achieve the purpose of improving intestinal function and facilitating bowel movement.

Hereinafter, the present invention will be described in more detail by way of Examples. However, these examples are for illustrative purposes only, and the scope of the present invention is not limited by these examples. In addition, it will be understood that terms not specifically defined herein have meanings commonly used in the technical field to which the present invention pertains.

Example

(1) Preparation of raw material complex extract

1) Pre-treatment step of raw material mixture

1-1) After washing kelp, eoseongcho, tungtungnodji, cornflower oil, licorice, and gilgyeong (purchased at the oriental medicine market in Dongdaemun-gu or online open market), cut them into pieces of about 0.5 cm, 1:1:1:1:1: It was mixed evenly in a weight ratio of 1. Thereafter, purified water was added to 300 g of the mixture, and left for about 15 minutes to allow the purified water to be absorbed into the raw material, and the raw material mixture was filtered through a sieve to remove moisture.

1-2) The obtained raw material mixture is frozen at a very low temperature of about -40 to -50 ° C using a freezer (QF-700), and the frozen raw material mixture is taken out at room temperature and left for about 3 to 4 hours ( thaw), and the above process (freezing and thawing) was repeated 3 additional times (total 4 times).

1-3) The raw material mixture subjected to the above freezing and thawing steps was dried by hot air drying, and then frozen at an ultra-low temperature of about -40 to -50°C to complete the raw material mixture pretreatment step.

2) Preparation of raw material complex extract

2-1) 100 g of the pre-treated raw material mixture is pulverized to a size of about 400 to 500 μm through a grinder in a frozen state, 80% (w/v) ethanol of about 10 times the volume is added, and then stirred for 10 minutes to homogenize did

2-2) The homogenized raw material mixture was extracted while maintaining the temperature at 60 to 80° C. while continuously stirring for 3 hours using an ultrasonic extractor (Power sonica, Hwasin Tech).

Thereafter, the obtained extract was cooled to 4° C., left for about 5 hours, and filtered through a filter (6 μm) to separate the filtrate and residues, and the filtrate (first extract) was stored separately.

2-3) After adding about 10 times the volume of purified water to the separated residue, homogenization by stirring for 10 minutes, hot water extraction at about 130 to 150° C. for 3 hours, and cooling the obtained extract to 4° C., After leaving it for about 5 hours, it was filtered through a filter (6 μm) to separate the filtrate and the residue, and the filtrate (the second extract) was stored separately.

2-4) Then, the first and second extracts were mixed, concentrated under reduced pressure and freeze-dried (Eyela NE, Tokyo, Japan) to prepare a raw material complex extract.

(2) Manufacturing of pills containing psyllium hull and raw material complex extract

Psyllium hulls (purchased in powder form in the open market) and raw material complex extract are mixed in a weight ratio of 1:1, and 80 wt% of a mixture of psyllium hulls and raw material complex extract based on the total weight of the pills through a known pill manufacturing method, 0.4 weight of magnesium hydroxide %, magnesium sulfate 0.4% by weight, fructooligosaccharide 2.4% by weight, a ring containing 4% by weight of salt was prepared.

Comparative Example 1

In the pretreatment step of the raw material mixture of the example, a ring containing a mixture of psyllium hull and raw material complex extract was prepared in substantially the same manner as in Example, except that the freezing and thawing of steps 1-2 were repeated a total of two times. did

Comparative Example 2

In the preparation of the raw material complex extract of Example, a ring containing a mixture of psyllium hull and raw material complex extract was prepared in substantially the same manner as in Example, except for extraction by the following method.

3-1) 100 g of the raw material mixture pretreated in steps 1-1 to 1-3 of the above example is pulverized to a size of about 400 to 500 μm through a grinder in a frozen state, and after administering about 10 times the volume of purified water, It was homogenized by stirring for 10 minutes.

3-2) The homogenized raw material mixture is subjected to hot water extraction at about 130 to 150° C. for 3 hours, and the obtained extract is cooled to 4° C., left to stand for about 5 hours, and filtered through a filter (6 μm). The liquid and the residue were separated, and the filtrate (1' extract) was stored separately.

3-3) After adding about 10 times the volume of 80% (w/v) ethanol to the separated residue, homogenize by stirring for 10 minutes, and ultrasonic extractor while maintaining the homogenized raw material mixture to be 60 to 80 ℃ (Power sonica, Hwashin Tech) was used for extraction while continuously stirring for 3 hours.

로 냉각시키고, 약 5시간 동안 방치시킨 후, 필터(6 ㎛)로 여과하여 여과액 및 잔사물을 분리하고, 여과액(제2' 복합추출물)은 따로 보관하였다.Then, the obtained extract was 4

After cooling with a furnace and leaving it for about 5 hours, it was filtered through a filter (6 μm) to separate the filtrate and the residue, and the filtrate (the 2nd 'complex extract) was stored separately.

3-4) Thereafter, the first and second extracts were mixed, concentrated under reduced pressure and freeze-dried (Eyela NE, Tokyo, Japan) to prepare a raw material complex extract.

experimental example. Confirmation of the effect of improving intestinal function and promoting bowel movements

In order to determine whether the composition of the present invention has an excellent effect of improving intestinal function and promoting bowel movement, an experiment was performed as follows.

Experimental participants were 40 women in their 20s and 40s who frequently experience constipation, and were divided into 4 groups and administered the pills of Examples and Comparative Examples 1 and 2 every morning/evening for 2 weeks with sufficient water at 10 g each. Ingestion was made, and if possible, it was ingested at a certain time.

In addition, it was recommended not to consume functional products or medicines for improving constipation during the experimental period, and to eat the same as usual.

The evaluation criteria are as follows, and the results are shown in Table 1 as average values.

[Evaluation standard]

1. Defecation frequency (%) - Calculated as the number of days of successful defecation during the experiment period

2. Change of bowel movement - Diarrhea 1 point, loose stool 2 points, normal stool 3 points, hard stool 4 points, small stool 5 points

3. Bowel pain - none at all 1 point, no 2 points, moderate 3 points, present 4 points, severe 5 points

4. Gas generation - None at all 1 point, No 2 points, Normal 3 points, Yes 4 points, Severe 5 points

5. Leftover feeling - None at all 1 point, No 2 points, Normal 3 points, Yes 4 points, Severe 5 points

6. Abdominal distension - None at all 1 point, None 2 points, Normal 3 points, Present 4 points, Severe 5 points

Example Comparative Example 1 Comparative Example 2 control group ^* Defecation frequency (%) 86 50 64 29 change of bowel 2.8 4.1 3.6 4.5 bowel pain 1.8 3.6 3.6 4.5 gas generation 2.3 3.6 3.2 4 leftover feeling 1.3 3.6 2.8 4 abdominal distension 1.8 3.9 3.3 4

( ^* Pills that do not contain psyllium hull and complex extract are provided)

As can be seen in Table 1 above, the experimental participants administered the Example showed improvements in all of the bowel movements, bowel changes, defecation pain, gas generation, feeling of defecation and abdominal distension compared to the control group.

In addition, in the case of Comparative Example 1 and Comparative Example 2 with a difference in the manufacturing method in the compound weight? y TT , respectively, there was an effect of improving the frequency of defecation, the degree of defecation, the degree of defecation, the pain of defecation, the generation of gas, the feeling of indigestion and the bloating of the abdomen, Examples also showed a significant improvement effect in comparison with this. This confirms that the effect of improving intestinal function and promoting bowel movement can be significantly increased even by the difference in the manufacturing method.

Claims (11)

psyllium hull; and
In the health functional food composition for improving intestinal function and facilitating bowel movements, including a complex extract of kelp, eoseongcho, tungtungnodji, cornflower oil, licorice and gilkyung,
The complex extract,
S1) washing and mixing kelp, eoseongcho, tungtungnodji, cornflower oil, licorice and gilgyeong, adding purified water and leaving it for 10 to 20 minutes, then removing the water;
S2) freezing the water-removed mixture at -40 to -50°C and then leaving it at room temperature for 3 to 4 hours;
S3) freezing the left mixture at -40 to -50°C after drying;
S4) pulverizing the raw material mixture in the frozen state, adding 80% (w/v) ethanol to the pulverized raw material mixture, and stirring to homogenize;
S5) sonicating the homogenized raw material mixture solution at 60 to 80° C. for 2 to 4 hours to perform ultrasonic extraction;
S6) separating the sonicated solution into a filtrate and a residue by filtering;
S7) adding purified water to the separated residue, followed by stirring to homogenize;
S8) hot water extraction of the homogenized solution at 130 to 150° C. for 2 to 4 hours;
S9) separating the heat-treated solution into a filtrate and a residue by filtering; and
S10) mixing the filtrate separated in steps S6 and S9;
The step S2 is repeated 3 to 5 times, a health functional food composition for improving intestinal function and facilitating defecation. According to claim 1,
The complex extract is a health functional food for improving intestinal function and facilitating bowel movement, which is extracted from a raw material mixture mixed with kelp, eoseongcho, tungtungnodji, cornflower oil, licorice and gilgyeong in a weight ratio of 1:1:1:1:1:1. composition. According to claim 1,
The health functional food composition for improving intestinal function and promoting bowel movement, wherein the psyllium hull and the complex extract are included in a weight ratio of 1:1. delete delete According to claim 1,
The pulverization of the step S4 is a health functional food composition for improving intestinal function and facilitating defecation that is performed so as to have a size of 400 to 500 μm. According to claim 1,
between steps S5 and S6; and cooling the extract obtained between steps S8 and S9 to 2 to 6° C., and leaving it to stand for 4 to 6 hours. A health functional food composition for improving intestinal function and promoting bowel movements. delete delete According to claim 1,
The composition is a health functional food composition for improving intestinal function and facilitating bowel movement, which further comprises mixed lactic acid bacteria. 11. The method of claim 10,
The mixed lactic acid bacteria are Lactobacillus acidophilus (Lactobacillus acidophilus), Lactobacillus bifidus (Lactobacillus bifidus), Lactobacillus acidophilus (lactobacilus acidophilus), Streptococcus faecalis (Streptococcus faecalis), Streptococcus faecium (Streptococcus faecalis), Streptococcus , Bacillus subtilis, Bacillus licheniformis, Bacillus polyfermenticus, Bacillus mesentericus, Saccharomyces cerevisiae, At least one intestine selected from the group consisting of Clostridium butyricum, Pediococcus pentosaceus, Enterococcus faecium and Bifidobacterium longum A health functional food composition for improving function and promoting bowel movements.