KR102272233B1 - 생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법 - Google Patents

생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법 Download PDF

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KR102272233B1
KR102272233B1 KR1020207024366A KR20207024366A KR102272233B1 KR 102272233 B1 KR102272233 B1 KR 102272233B1 KR 1020207024366 A KR1020207024366 A KR 1020207024366A KR 20207024366 A KR20207024366 A KR 20207024366A KR 102272233 B1 KR102272233 B1 KR 102272233B1
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capture
protein
bioactive agent
ligand
bound
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KR20200103867A (ko
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캐롤린 더블유. 히트코
로빈 허스트
토마스 커클랜드
디터 클라우버트
폰초 마이젠하이머
니드히 나스
레이첼 에프. 오하나
폴 오토
마제타 어
해리 테츠오 우에다
키이스 우드
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프로메가 코포레이션
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
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  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
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  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020207024366A 2012-12-12 2013-12-12 생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법 Active KR102272233B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261736426P 2012-12-12 2012-12-12
US61/736,426 2012-12-12
US201361788313P 2013-03-15 2013-03-15
US61/788,313 2013-03-15
KR1020157018280A KR102227321B1 (ko) 2012-12-12 2013-12-12 생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법
PCT/US2013/074756 WO2014093671A1 (en) 2012-12-12 2013-12-12 Compositions and methods for capture of cellular targets of bioactive agents

Related Parent Applications (1)

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KR1020157018280A Division KR102227321B1 (ko) 2012-12-12 2013-12-12 생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법

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KR20200103867A KR20200103867A (ko) 2020-09-02
KR102272233B1 true KR102272233B1 (ko) 2021-07-01

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KR1020207024366A Active KR102272233B1 (ko) 2012-12-12 2013-12-12 생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법
KR1020157018280A Active KR102227321B1 (ko) 2012-12-12 2013-12-12 생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법

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US (2) US9551705B2 (enExample)
EP (1) EP2931305B1 (enExample)
JP (2) JP6484178B2 (enExample)
KR (2) KR102272233B1 (enExample)
CN (1) CN104853767B (enExample)
AU (2) AU2013359160B2 (enExample)
BR (1) BR112015013715A2 (enExample)
CA (1) CA2894432C (enExample)
IL (1) IL239213B (enExample)
SG (1) SG11201504520XA (enExample)
WO (1) WO2014093671A1 (enExample)

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US10168323B2 (en) 2013-03-15 2019-01-01 Promega Corporation Compositions and methods for capture of cellular targets of bioactive agents
US11072811B2 (en) 2013-03-15 2021-07-27 Promega Corporation Substrates for covalent tethering of proteins to functional groups or solid surfaces
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US10458988B2 (en) * 2017-03-03 2019-10-29 Musc Foundation For Research Development Biotinylated luminescent probe
US12180581B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US11709155B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US11709156B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved analytical analysis
US12181452B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
JP7584433B2 (ja) 2019-03-20 2024-11-15 プロメガ コーポレイション 光親和性プローブ
US11918936B2 (en) 2020-01-17 2024-03-05 Waters Technologies Corporation Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding
CN116391122A (zh) 2020-09-24 2023-07-04 沃特世科技公司 用于反应性分子分离的色谱硬件改进
JP2022182394A (ja) * 2021-05-28 2022-12-08 独立行政法人国立病院機構 抗原固相化デバイス
WO2023287984A1 (en) * 2021-07-14 2023-01-19 University Of Maryland, Baltimore Suberoylanilide hydroxamic acid (saha) drugs, conjugates, and nanoparticles, and methods of use thereof

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US10168323B2 (en) 2013-03-15 2019-01-01 Promega Corporation Compositions and methods for capture of cellular targets of bioactive agents
JP6876002B2 (ja) * 2015-06-05 2021-05-26 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 機能的要素を共有結合により係留させるための細胞透過性、細胞適合性、かつ開裂可能であるリンカー

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AU2013359160A2 (en) 2015-11-12
CN104853767B (zh) 2017-04-05
IL239213A0 (en) 2015-07-30
JP6484178B2 (ja) 2019-03-13
AU2013359160A1 (en) 2015-07-09
AU2019201035B2 (en) 2020-09-03
EP2931305A1 (en) 2015-10-21
CN104853767A (zh) 2015-08-19
US20140199712A1 (en) 2014-07-17
CA2894432C (en) 2022-06-07
IL239213B (en) 2020-03-31
KR102227321B1 (ko) 2021-03-12
AU2019201035A1 (en) 2019-03-07
CA2894432A1 (en) 2014-06-19
KR20150093222A (ko) 2015-08-17
SG11201504520XA (en) 2015-07-30
AU2013359160B2 (en) 2018-11-15
AU2019201035B9 (en) 2021-02-11
US9551705B2 (en) 2017-01-24
WO2014093671A1 (en) 2014-06-19
US10976312B2 (en) 2021-04-13
US20170115283A1 (en) 2017-04-27
EP2931305A4 (en) 2016-08-17
EP2931305B1 (en) 2018-11-28
JP6999589B2 (ja) 2022-02-04
KR20200103867A (ko) 2020-09-02
JP2016502843A (ja) 2016-02-01
JP2019092517A (ja) 2019-06-20
BR112015013715A2 (pt) 2017-09-26

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