KR102086389B1 - 트리아졸 화합물의 제조 방법 - Google Patents
트리아졸 화합물의 제조 방법 Download PDFInfo
- Publication number
- KR102086389B1 KR102086389B1 KR1020147033989A KR20147033989A KR102086389B1 KR 102086389 B1 KR102086389 B1 KR 102086389B1 KR 1020147033989 A KR1020147033989 A KR 1020147033989A KR 20147033989 A KR20147033989 A KR 20147033989A KR 102086389 B1 KR102086389 B1 KR 102086389B1
- Authority
- KR
- South Korea
- Prior art keywords
- formula
- compound
- sodium
- mixture
- triazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- MCDFEIVDMAYOQV-UHFFFAOYSA-N CCCOC(C[n]1nncc1)=O Chemical compound CCCOC(C[n]1nncc1)=O MCDFEIVDMAYOQV-UHFFFAOYSA-N 0.000 description 1
- AGSWPQLILCPNIX-UHFFFAOYSA-N N#CCOC(C[n]1nccn1)=O Chemical compound N#CCOC(C[n]1nccn1)=O AGSWPQLILCPNIX-UHFFFAOYSA-N 0.000 description 1
- IJMBOKOTALXLKS-UHFFFAOYSA-N O=C1N(c2ncnc(N3CCOCC3)c2)NC=C1[n]1nncc1 Chemical compound O=C1N(c2ncnc(N3CCOCC3)c2)NC=C1[n]1nncc1 IJMBOKOTALXLKS-UHFFFAOYSA-N 0.000 description 1
- NTIRTFLRBFAPSX-UHFFFAOYSA-N Oc([n](-c1ncnc(N2CCOCC2)c1)nc1)c1-[n]1nncc1 Chemical compound Oc([n](-c1ncnc(N2CCOCC2)c1)nc1)c1-[n]1nncc1 NTIRTFLRBFAPSX-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12167152.3 | 2012-05-08 | ||
| EP12167152 | 2012-05-08 | ||
| PCT/EP2013/059418 WO2013167552A1 (de) | 2012-05-08 | 2013-05-06 | Verfahren zur herstellung von triazol-verbindungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20150018534A KR20150018534A (ko) | 2015-02-23 |
| KR102086389B1 true KR102086389B1 (ko) | 2020-03-09 |
Family
ID=48325714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147033989A Active KR102086389B1 (ko) | 2012-05-08 | 2013-05-06 | 트리아졸 화합물의 제조 방법 |
Country Status (35)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2639716B2 (ja) | 1988-12-14 | 1997-08-13 | 横浜ゴム株式会社 | タイヤ成形装置に於けるグリーンタイヤの搬送装置 |
| JOP20170103A1 (ar) * | 2016-05-03 | 2017-11-03 | Bayer Pharma AG | عملية لتحضير مشتقات 1-فنيل-1، 2، 4-تريازول مستبدلة بـ 5-هيدروكسي ألكيل |
| CN108084099B (zh) * | 2017-12-20 | 2019-01-29 | 天驰药业有限公司 | 一种1,2,3-三氮唑化合物的合成方法 |
| US10702525B1 (en) | 2019-09-04 | 2020-07-07 | United Arab Emirates University | Pyrimidine derivatives as anti-diabetic agents |
| EP3888684A1 (en) | 2020-03-31 | 2021-10-06 | Bayer Animal Health GmbH | Composition having improved voluntary acceptance |
| JP7710897B2 (ja) * | 2021-06-01 | 2025-07-22 | 三菱ガス化学ネクスト株式会社 | １－アルキル－５－ヒドロキシピラゾールの製造方法 |
| CN114264752B (zh) * | 2021-12-29 | 2023-08-15 | 北京金城泰尔制药有限公司 | 溴乙酸甲酯的检测方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK135184A (da) | 1983-03-03 | 1984-10-10 | Riker Laboratories Inc | Triazol(4,3-c)- og triazol(1,5-c)pyrimidiner |
| US4572910A (en) * | 1983-03-03 | 1986-02-25 | Riker Laboratories, Inc. | Triazolo[1,5-c]pyrimidines substituted by nitrogen-containing heterocyclic rings |
| US4752910A (en) | 1984-10-30 | 1988-06-21 | Prime Computer, Inc. | Method and apparatus for continuous after-imaging |
| UY27813A1 (es) * | 2002-05-31 | 2003-12-31 | Smithkline Beecham Corp | Inhibidores de la peptido-desformilasa |
| CL2003002353A1 (es) | 2002-11-15 | 2005-02-04 | Vertex Pharma | Compuestos derivados de diaminotriazoles, inhibidores d ela proteina quinasa; composicion farmaceutica; procedimiento de preparacion; y su uso del compuesto en el tratamiento de enfermedades de desordenes alergicos, proliferacion, autoinmunes, condic |
| WO2005044785A1 (en) * | 2003-10-30 | 2005-05-19 | Merck & Co., Inc. | Aralkyl amines as cannabinoid receptor modulators |
| US7745630B2 (en) | 2003-12-22 | 2010-06-29 | Justin Stephen Bryans | Triazolyl piperidine arginine vasopressin receptor modulators |
| DE102008020113A1 (de) | 2008-04-23 | 2009-10-29 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Dihydropyrazolone und ihre Verwendung |
| EP1877399A1 (en) | 2005-04-26 | 2008-01-16 | Pfizer Limited | Triazole derivatives as vasopressin antagonists |
| CA2608718A1 (en) | 2005-05-18 | 2006-11-23 | Pfizer Limited | 1, 2, 4-triazole derivatives as vasopressin antagonists |
| DE102006050516A1 (de) * | 2006-10-26 | 2008-04-30 | Bayer Healthcare Ag | Substituierte Dihydropyrazolone und ihre Verwendung |
| DE102010041236A1 (de) * | 2010-09-23 | 2012-03-29 | Osram Ag | Optoelektronisches Halbleiterbauelement |
| DE102010044131A1 (de) * | 2010-11-18 | 2012-05-24 | Bayer Schering Pharma Aktiengesellschaft | Substituiertes Natrium-1H-pyrazol-5-olat |
-
2013
- 2013-05-06 AU AU2013258107A patent/AU2013258107B2/en active Active
- 2013-05-06 EP EP13720943.3A patent/EP2847183B1/de active Active
- 2013-05-06 WO PCT/EP2013/059418 patent/WO2013167552A1/de not_active Ceased
- 2013-05-06 HU HUE13720943A patent/HUE034430T2/en unknown
- 2013-05-06 RS RS20170869A patent/RS56255B1/sr unknown
- 2013-05-06 SG SG10201609319YA patent/SG10201609319YA/en unknown
- 2013-05-06 MX MX2014013448A patent/MX350519B/es active IP Right Grant
- 2013-05-06 ES ES13720943.3T patent/ES2641205T3/es active Active
- 2013-05-06 PL PL13720943T patent/PL2847183T3/pl unknown
- 2013-05-06 JP JP2015510775A patent/JP6149104B2/ja active Active
- 2013-05-06 HR HRP20171321TT patent/HRP20171321T1/hr unknown
- 2013-05-06 CN CN201380036548.5A patent/CN104411704B/zh active Active
- 2013-05-06 SI SI201330768T patent/SI2847183T1/sl unknown
- 2013-05-06 DK DK13720943.3T patent/DK2847183T3/en active
- 2013-05-06 BR BR112014027564-5A patent/BR112014027564B1/pt active IP Right Grant
- 2013-05-06 PT PT137209433T patent/PT2847183T/pt unknown
- 2013-05-06 AP AP2014008089A patent/AP2014008089A0/xx unknown
- 2013-05-06 PE PE2014001942A patent/PE20142453A1/es active IP Right Grant
- 2013-05-06 US US14/399,929 patent/US10301289B2/en active Active
- 2013-05-06 EA EA201492032A patent/EA027804B1/ru not_active IP Right Cessation
- 2013-05-06 SG SG11201407043PA patent/SG11201407043PA/en unknown
- 2013-05-06 MY MYPI2014703274A patent/MY184577A/en unknown
- 2013-05-06 LT LTEP13720943.3T patent/LT2847183T/lt unknown
- 2013-05-06 KR KR1020147033989A patent/KR102086389B1/ko active Active
- 2013-05-06 CA CA2872726A patent/CA2872726C/en active Active
- 2013-05-06 UA UAA201413001A patent/UA116349C2/uk unknown
- 2013-05-06 NZ NZ701661A patent/NZ701661A/en unknown
-
2014
- 2014-11-02 IL IL235441A patent/IL235441A/en active IP Right Grant
- 2014-11-04 CO CO14243310A patent/CO7121324A2/es unknown
- 2014-11-06 CL CL2014003003A patent/CL2014003003A1/es unknown
- 2014-11-06 CU CU2014000128A patent/CU20140128A7/es unknown
- 2014-11-06 PH PH12014502482A patent/PH12014502482A1/en unknown
- 2014-11-07 TN TN2014000469A patent/TN2014000469A1/fr unknown
- 2014-11-07 CR CR20140514A patent/CR20140514A/es unknown
- 2014-11-07 DO DO2014000254A patent/DOP2014000254A/es unknown
- 2014-11-21 ZA ZA2014/08571A patent/ZA201408571B/en unknown
-
2016
- 2016-05-13 CL CL2016001165A patent/CL2016001165A1/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR102086389B1 (ko) | 트리아졸 화합물의 제조 방법 | |
| HU230577B1 (hu) | Eljárás 2-etoxi-1-((2'-(5-oxo-4,5-dihidro-1,2,4-oxadiazol-3-il)-bifenil-4-il)-metil)-1H-benzol[d]imidazol7-karboxilátok előállítására és ezek átalakítása azilsartanná | |
| JP2020518573A (ja) | ２−（［１，２，３］トリアゾール−２−イル）−安息香酸誘導体の製造 | |
| KR102458638B1 (ko) | 메데토미딘의 합성에서 유용한 3-아릴부탄알과 같은 화합물의 제조 방법 | |
| US6664401B2 (en) | Process for preparing isocoumarins | |
| Karandeeva et al. | Synthesis of spiro [chromane-2, 4'-pyrimidines] by condensation of 6-styryldihydropyrimidin-2-ones with resorcinols | |
| Shuangxia et al. | An efficient and green synthetic route to losartan | |
| Vraničar et al. | Synthesis and transformations of a pyrazole containing α, β-didehydro-α-amino acid derivatives | |
| BR112012029363B1 (pt) | Processo para preparar 1-alquil-3-difluorometil-5 -hidroxipirazóis | |
| HK1208027B (en) | Method for the preparation of triazole compounds | |
| JP4541143B2 (ja) | キノリン誘導体の製造方法 | |
| JP2984848B2 (ja) | Ｎ―アルキルピラゾール誘導体の製法 | |
| JP3855686B2 (ja) | ３，３−ジアルコキシ−２−ヒドロキシイミノ誘導体及びその製造法 | |
| WO2020234379A1 (en) | Processes and intermediates for preparing a btk inhibitor | |
| US20040116732A1 (en) | 3,3-Dialkoxy-2-hydroxyiminopropionitriles, process for preparation thereof and process of preparing 5-amino-4-nitrosopyrazoles or salts thereof by the use of the same | |
| JP2002363171A (ja) | ４−置換−３−アミノイソオキサゾール誘導体の製法 | |
| JP2008540351A (ja) | ５−アルキルチオアルキルアミノ−１−フェニル−ピラゾールを製造する方法 | |
| MX2008009034A (en) | Process for preparing substituted biphenyls | |
| JP2001058983A (ja) | １−置換５−ヒドロキシ−イミダゾリン−２，４−ジオン類及び１−置換５−アルコキシ−イミダゾリン−２，４−ジオン類の製造方法 | |
| JPH0114907B2 (https=) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| A201 | Request for examination | ||
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
|
| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
|
| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U12-oth-PR1002 Fee payment year number: 1 |
|
| PG1601 | Publication of registration |
St.27 status event code: A-4-4-Q10-Q13-nap-PG1601 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 4 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 5 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 6 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 7 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-OTH-PR1001 (AS PROVIDED BY THE NATIONAL OFFICE) Year of fee payment: 7 |