KR102082247B1 - 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제 - Google Patents

개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제 Download PDF

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KR102082247B1
KR102082247B1 KR1020177015121A KR20177015121A KR102082247B1 KR 102082247 B1 KR102082247 B1 KR 102082247B1 KR 1020177015121 A KR1020177015121 A KR 1020177015121A KR 20177015121 A KR20177015121 A KR 20177015121A KR 102082247 B1 KR102082247 B1 KR 102082247B1
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KR20170066694A (ko
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매튜 루드
나 트린
안드레아스 셔머
제이콥 가노
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알이지 라이프 사이언시스, 엘엘씨
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Assigned to 게노마티카 인코포레이티드 reassignment 게노마티카 인코포레이티드 권리의 전부이전등록 Assignors: 알이지 라이프 사이언시스, 엘엘씨
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0108—Long-chain acyl-[acyl-carrier-protein] reductase (1.2.1.80)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fats And Perfumes (AREA)
KR1020177015121A 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제 Expired - Fee Related KR102082247B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020207004969A KR102265148B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361753273P 2013-01-16 2013-01-16
US61/753,273 2013-01-16
PCT/US2014/011859 WO2014113571A2 (en) 2013-01-16 2014-01-16 Acyl-acp reductase with improved properties

Related Parent Applications (1)

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KR1020157021992A Division KR101746040B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제

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KR20170066694A KR20170066694A (ko) 2017-06-14
KR102082247B1 true KR102082247B1 (ko) 2020-02-28

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KR1020217017654A Ceased KR20210072147A (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020157021992A Active KR101746040B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020207004969A Expired - Fee Related KR102265148B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제

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KR1020157021992A Active KR101746040B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020207004969A Expired - Fee Related KR102265148B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제

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US (6) US9683219B2 (https=)
EP (3) EP3385375B1 (https=)
JP (5) JP6063585B2 (https=)
KR (4) KR102082247B1 (https=)
CN (3) CN110387352A (https=)
AU (3) AU2014207522B2 (https=)
BR (1) BR112015017005A2 (https=)
CA (2) CA3143642A1 (https=)
CO (1) CO7461134A2 (https=)
ES (2) ES2600354T3 (https=)
MX (2) MX346830B (https=)
MY (1) MY167434A (https=)
WO (1) WO2014113571A2 (https=)

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US20150119601A1 (en) 2013-03-15 2015-04-30 Opx Biotechnologies, Inc. Monofunctional mcr + 3-hp dehydrogenase
EP3022310B1 (en) 2013-07-19 2019-10-16 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
EP4089176A1 (en) * 2014-07-18 2022-11-16 Genomatica, Inc. Microbial production of 1,3 diols
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
US11345938B2 (en) 2017-02-02 2022-05-31 Cargill, Incorporated Genetically modified cells that produce C6-C10 fatty acid derivatives
MY205555A (en) 2017-04-03 2024-10-25 Genomatica Inc Thioesterase variants having improved activity for the production of medium-chain fatty acid derivatives
EP3844179A4 (en) 2018-08-31 2022-08-31 Genomatica, Inc. XYLR MUTANT FOR IMPROVED XYLOSE UTILIZATION OR IMPROVED CO-UTILIZATION OF GLUCOSE AND XYLOSE
US12221644B2 (en) 2018-08-31 2025-02-11 Genomatica, Inc. Production of non-native monounsaturated fatty acids in bacteria
EP4493683A1 (en) 2022-03-16 2025-01-22 Genomatica, Inc. Acyl-acp thioesterase variants and uses thereof

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WO2014113571A3 (en) 2014-11-13
MX346830B (es) 2017-04-03
BR112015017005A2 (pt) 2017-08-15
EP3385375B1 (en) 2021-06-16
EP2946009B1 (en) 2016-07-27
AU2017200596A1 (en) 2017-02-23
EP3103867A1 (en) 2016-12-14
CN110387352A (zh) 2019-10-29
JP6523393B2 (ja) 2019-05-29
KR101746040B1 (ko) 2017-06-13
JP2017209118A (ja) 2017-11-30
CN105051189B (zh) 2019-08-06
JP2019141083A (ja) 2019-08-29
KR20170066694A (ko) 2017-06-14
AU2017200596B2 (en) 2019-01-24
KR20150105471A (ko) 2015-09-16
JP6063585B2 (ja) 2017-01-18
AU2014207522A1 (en) 2015-05-07
EP3385375A1 (en) 2018-10-10
EP2946009A2 (en) 2015-11-25
WO2014113571A2 (en) 2014-07-24
US20170342388A1 (en) 2017-11-30
CO7461134A2 (es) 2015-11-30
US10208294B2 (en) 2019-02-19
CA2898317A1 (en) 2014-07-24
AU2019202790A1 (en) 2019-05-16
KR102265148B1 (ko) 2021-06-15
US11130944B2 (en) 2021-09-28
MY167434A (en) 2018-08-28
KR20200020998A (ko) 2020-02-26
JP2021006067A (ja) 2021-01-21
CA3143642A1 (en) 2014-07-24
US20160348080A1 (en) 2016-12-01
JP6211162B2 (ja) 2017-10-11
CN109897834A (zh) 2019-06-18
ES2600354T3 (es) 2017-02-08
CA2898317C (en) 2022-03-01
JP7094343B2 (ja) 2022-07-01
JP2016503663A (ja) 2016-02-08
JP6926143B2 (ja) 2021-08-25
US9683219B2 (en) 2017-06-20
JP2017042170A (ja) 2017-03-02
US20220090028A1 (en) 2022-03-24
US20150361454A1 (en) 2015-12-17
EP3103867B1 (en) 2018-05-16
KR20210072147A (ko) 2021-06-16
MX2015009138A (es) 2015-11-06
US20240117324A1 (en) 2024-04-11
US9873865B2 (en) 2018-01-23
US20200010813A1 (en) 2020-01-09
CN105051189A (zh) 2015-11-11
AU2014207522B2 (en) 2016-12-15
MX356997B (es) 2018-06-22
ES2675224T3 (es) 2018-07-09
US12173329B2 (en) 2024-12-24

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