KR102050585B1 - Phlorotannin composition having inhibitory effect on induction of gray hair and promoting effect on induction of dark hair - Google Patents

Abstract

The present invention relates to a composition having the effect of preventing and improving the discoloration of the hair used in the scalp. More specifically, the present invention relates to a use and related products for preventing and improving the discoloration of hair by applying a composition comprising phlorotannin as an active ingredient to the scalp in the form of soap, shampoo or hair tonic.

Description

Phloorotannin composition having inhibitory effect on induction of gray hair and promoting effect on induction of dark hair}

The present invention relates to a composition for preventing hair loss and black hair comprising a phlorotannin compound and a product comprising the same.

Human hair color is determined by the combination of eumelanin and pheomelanin synthesized in melanocytes (melanin producing cells) present in hair follicles.

Degradation of melanocytes leads to a decrease in melanin synthesis and causes gray hair. Major causes of melanocyte deterioration include genetic defects, hormonal abnormalities, aging, stress, exposure to toxins and chemicals. Nutrients such as protein, iron, copper, zinc and biotin can also cause gray hair.

In normal hair follicles, melanocyte stem cells are activated to form melanocytes and function normally. On the other hand, when aging occurs, melanocyte stem cells decrease, causing melanocyte deterioration and cell number reduction. On the other hand, gray hair is increasingly generated in young people due to environmental pollution, job stress, and shortage of essential nutrients due to increased intake of instant foods as the industrial environment is advanced. In addition, the intake of metabolic syndrome is increasing due to the excessive intake of nutrients, the occurrence of metabolic syndrome causes abnormal blood flow in the body, decreases the function of nutrient supply, waste removal, etc., adversely affect the cells and cause gray hair .

If you have gray hair, you may look older than your age, make styling difficult, and reduce your personal satisfaction. As a complementary measure, wigs, dyes, and medicines may be used, but there are disadvantages of high cost, hassle, and side effects. In particular, hair staining not only deteriorates hair health, but may also cause allergic or inflammatory reactions caused by chemicals, and hair loss. In addition, there is an inconvenience to be carried out periodically, there is a problem that often unnatural colors are produced.

Republic of Korea Patent Publication 10-2015-0124193

1.Inhibitory Effect of Phlorotannins Isolated from Ecklonia cava on Mushroom Tyrosinase Activity and Melanin formation in Mouse B16F10 Melanoma Cells, J. Agric. Food Chem., 2009, 57 (10), pp 4124-4129, NY Yoon et al., 2. Phlorotannins as bioactive agents from brown algae, 2011, Process Biochemistry 46, pp 2219-2224, YX Li et al.

Relieves the problems caused by chemicals used for hair dyeing, the cost and time required for dyeing, and provides natural ingredients to maintain and restore the natural color of hair. We will fundamentally solve the problem of.

In order to achieve the above object, the present invention provides a composition for preventing white hair and promoting black hair, including phlorotannin as an active ingredient.

In another aspect, the present invention provides a scalp application for preventing white hair and promoting black hair comprising the composition.

Compositions and products containing the phlorotannin of the present invention as an active ingredient is easy to use as a natural derived material and has an effect of blackening gray hair, and thus may be usefully used for improving gray hair.

Compositions and products containing the phlorotannin of the present invention as an active ingredient has the advantage that can be used as a natural derived material without side effects.

1 is a graph showing the improvement effect of the composition-added soap of the present invention.
Figure 2 is a graph showing the improvement effect of the composition added shampoo of the present invention.
Figure 3 is a graph showing the improvement effect of the composition tonic of the present invention.
Figure 4 is a comparison photograph before and after using the composition 1 addition soap of the present invention.
Figure 5 is a comparison photograph before and after use of the composition 4 addition shampoo of the present invention.
Figure 6 is a comparison photograph before and after the use of the composition 3 addition tonic of the present invention.

Hereinafter, the present invention will be described in detail.

Phlorotannin is a polyphenolic substance, and according to many prior art, phlorotannin is known to have a function of inhibiting melanin production. (Reference: 1.Inhibitory Effect of Phlorotannins Isolated from Ecklonia cava on Mushroom Tyrosinase Activity and Melanin formation in Mouse B16F10 Melanoma Cells, J. Agric.Food Chem ., 2009, 57 (10), pp 4124-4129, NY Yoon et al Phlorotannins as bioactive agents from brown algae, 2011, Process Biochemistry 46, pp2219-2224, YX Li et al.) Nevertheless, we accidentally block melanin production when phlorotannin is applied to common skin. Unlike the whitening effect, when applied to the scalp and hair, the melanin formation of the hair is promoted on the contrary, and the hair which has been discolored in white turns to the original color from the hair root. The invention has been completed by developing scalp application compositions and products.

The composition for improving gray hair comprising the phlorotannin of the present invention as an active ingredient prevents the formation of gray hair and promotes the production of black hair.

The composition for preventing and improving gray hair of the present invention may include 20-100% by weight of the phlorotannin compound.

The phlorotannin is a naturally occurring component and can be obtained by all conventional methods. That is, they may be synthesized using commercially available reagents, or may be obtained by extracting and separating from natural products, particularly seaweeds.

The phlorotannin can be extracted from algae, especially brown algae, specifically, rhubarb (Eisenia bicyclis), Eisenia arborea, Eisenia desmarestioides, Esenia galapazennis (Eisenia galapagensis), Eisenia masonii, Ecklonia kurome, Ecklonia cava, Ecklonia stolonifera, Ecklonia maxima, Eclonia radiata, Eclonia bicyclis, Eclonia biruncinate, Eclonia buccinalis, Eclonia caepaestipes, Eclonia exasperta , Eclonia fastigiata, Eclonia brevipes, Eclonia arborea, Eclonia latifoli ifolia, Eclonia muratii, Eclonia radicosa, Eclonia richardiana and Eclonia wrightii.

The composition of the present invention may additionally contain 0-80% by weight of a component consisting of mannitol, alginic acid, fucoidan, laminaran, and fucosterol, fucoxanthin, and the like as carbohydrate components in addition to phlorotannin.

The composition of the present invention may include at least one phlorotannin selected from compounds having the following Chemical Formulas 1 to 12 as an active ingredient.

[Formula 1]

[Formula 2]

[Formula 3]

[Formula 4]

[Formula 5]

[Formula 6]

[Formula 7]

[Formula 8]

[Formula 9]

[Formula 10]

[Formula 11]

[Formula 12]

The composition of the present invention may include at least one phlorotannin selected from Formula 2, Formula 4, Formula 5, and Formula 8 as an active ingredient.

The composition of the present invention may include two or more phlorotannins selected from Chemical Formulas 2, 4, 5 and 8 as the active ingredient.

The composition of the present invention is 1-60% by weight of fluorotannin of formula 2, 0.3-20% by weight of fluorotannin of formula 4, 0.1-10% by weight of fluorotannin of formula 5 and floro of formula 8 Tannins may comprise 0.1-5% by weight.

The composition of the present invention may include 1-65% by weight of fluorotannin of Formula 2 and 0.3-45% by weight of fluorotannin of Formula 4, based on the total weight.

The composition of the present invention may include 1-45% by weight of fluorotannin of Formula 5 and 0.3-45% by weight of fluorotannin of Formula 8, based on the total weight.

The composition of the present invention is 0.1 to 3% by weight of fluorotannin of formula 1, 5 to 21% by weight of fluorotannin of formula 2, 1 to 3% by weight of fluorotannin of formula 3, 0.5 to 5 of fluorotannin of formula 4 % By weight, 0.1 to 7% by weight of fluorotannin of formula 5, 0.5 to 8% by weight of fluorotannin of formula 6, 0.1 to 1% by weight of fluorotannin of formula 7, 0.1 to 8% by weight of fluorotannin of formula 8 0.1 to 2% by weight of fluorotannin of formula 9, 0.1 to 7% by weight of fluorotannin of formula 10, 0.1 to 3% by weight of fluorotannin of formula 11, and 0.1 to 4% by weight of fluorotannin of formula 12 can do.

The composition of the present invention is 20-100% by weight of phlorotannin, 0-30% by weight of mannitol, 0-25% by weight of alginic acid, 0-25% by weight of fucoidan, 0-10% by weight of fucosterol, 0-10% by weight of fucoxanthin , Lamina may include 0 to 10% by weight.

The composition of the present invention is 20 to 97% by weight fluorotannin, 1 to 30% by weight mannitol, 1 to 25% by weight alginic acid, 0.5 to 25% by weight fucoidan, 0.1 to 10% by weight fucosterol, 0.1 to 10% by weight fucoxanthin , Lamina may include 0.1 to 10% by weight.

The present invention provides a gray hair improvement product comprising the phlorotannin composition.

The product may be in the form of a soap, tonic, shampoo or the like.

The phlorotannin in the product may be included in an amount of 0.01 to 5% by weight, preferably 0.02 to 4% by weight, more preferably 0.03 to 3% by weight, based on the total weight of the product. When phlorotannin is included in the above amount, the baldness improving effect is excellent.

Product of the present invention may further comprise 0.01 to 0.5% by weight of ascorbic acid (Ascirbic acid).

Soap of the present invention is the phlorotannin composition and palm, coconut, castor, castor, olive, canola, evening primrose, camellia, peanut, corn, flaxseed, red palm, rosehip, macadamia nut, cotton yarn, rice bran, mink, babasu, It may include two or more selected from oil, lanolin, lard extracted from baobab, citron, sunflower, hamp, jojoba, safflower seed, argan and the like. The tonic of the present invention may include the phlorotannin composition, purified water, and at least one selected from ethanol, glycerin, salicylic acid, and menthol. The shampoo of the present invention is the fluorotannin composition, purified water, and glycerin, natural vitamin E, sodium laureth sulfate, cocamidopropyl betaine, propylene glycol, glycol distearate, tablet salt, Polyquaternium-7 (Polyquaternium-7), may include one or more selected from citric acid and flavoring.

The daily amount of phlorotannin contained in the composition for preventing and improving hair decoloration of the present invention is preferably about 0.1 to 50 mg, but the amount is not limited to the above range. If the daily usage is in the above range, the baldness improving effect is excellent.

Hereinafter, the present invention will be described in more detail with reference to Examples. However, the following examples are intended to illustrate the present invention in more detail, and the scope of the present invention is not limited by the following examples. The following examples can be appropriately modified and changed by those skilled in the art within the scope of the present invention.

Example 1 Preparation of a Composition Containing Phlorotannin

In order to prepare a composition comprising the phlorotannin of the present invention as an active ingredient was extracted from the domestic brown algae by the following method.

Ecklonia cava was washed with distilled water to remove foreign substances, dried in the shade, and then crushed. 500 g of the Ecklonia cava was added to an extraction container, and 20 wt% of 30 wt% alcohol solution was added to the weight of Ecklonia cava, and reflux extraction was performed at 75 to 80 ° C. for 4 hours to obtain an extract. The extract was filtered through a 10 μm filter network, and the filtered extract was concentrated under reduced pressure to obtain a primary extract concentrate. The primary extract concentrate was dried with a vacuum dryer and then ground to obtain 170 g of composition 1.

The composition 1 was dissolved in hot water at 50 ° C., adsorbed onto an adsorption resin, washed with water and eluted with alcohol to obtain an eluate of phlorotannin. The eluate was filtered through a 1 μm filter network, and the filtered extract was concentrated under reduced pressure to obtain a secondary extract concentrate. The secondary extract concentrate was dried with a vacuum dryer, and then ground to obtain 30 g of a composition 2.

Thereafter, the composition 2 was suspended in 20 times distilled water, and extracted three times with the same amount of ethyl acetate solvent to obtain an ethyl acetate fraction. The ethyl acetate fractions were concentrated under reduced pressure, and the concentrated solution was dried with a vacuum dryer, and then ground to obtain 10 g of composition 3.

Composition 3 was dissolved in 30% methanol and then compositions 4 and 5 were separated using reverse phase chromatography. Separation was carried out using an aqueous 15 ~ 80% methanol solution, concentrated solution separated by 15 ~ 30% aqueous methanol solution to obtain a composition 4 2g, concentrated solution 5 separated by 30 ~ 80% aqueous methanol solution 7g was obtained.

Compounds 1 to 5 obtained above were loaded on liquid chromatography to separate compounds. In this case, it was confirmed that the obtained compound is a compound of Chemical Formulas 1 to 12 by using a compound structure analyzer NMR. Each of the compositions 1 to 5 prepared above was dissolved in 60% methanol, filtered through a 0.2 μm membrane filter, and loaded into high performance liquid chromatography. In high performance liquid chromatography, the column was HP ODS Hypersil, the solvent was distilled water and methanol, and the solvent was supplied with a linear gradient over 30 minutes from 15% to 70% methanol at a flow rate of 1.0 ml / min. As a result of the analysis, the presence of the compound of Chemical Formulas 1 to 12 was confirmed. Chemical compositions of the extracted Compositions 1 to 5 are shown in Table 1 below.

sample Composition of the sample Composition 1 2% by weight of Formula 2, 1% by weight of Formula 4, 0.5% by weight of Formula 5, 0.3% by weight of Formula 8, 20% by weight of total phlorotannin including 16.2% by weight of a single product of Formula 1-12, 25% by weight of mannitol %, Alginic acid 20%, Fucoidan 20%, Fucosterol 5%, Fucoxanthin 5%, Laminaran 5% by weight Composition 2 10% by weight of total phlorotannin, including 10% by weight of Formula 2, 3% by weight of Formula 4, 1% by weight of Formula 5, 1.5% by weight of Formula 8, and other 54.5% by weight of a single substance of Formula 1-12 , 6% by weight of alginic acid, 6% by weight of fucoidan, 3% by weight of fucosterol, 3% by weight of fucoxanthin, 2% by weight of laminaran Composition 3 100% by weight total phlorotannin, including 17% by weight of Formula 2, 5% by weight of Formula 4, 5% by weight of Formula 5, 3% by weight of Formula 8, and 70% by weight of other monoliths of Formula 1-12 Composition 4 100% by weight total phlorotannin, including 50% by weight of Formula 5, 46% by weight of Formula 8, and 4% by weight of a single product of Formula 1-12 Composition 5 100% by weight total phlorotannin, including 63% by weight of Formula 2, 34% by weight of Formula 4, and 3% by weight of a single substance of Formula 1-12

Example 2. Soap Preparation Using Composition

After dissolving 125 g caustic soda in 264 g of distilled water, it is lowered to 65 ° C. and mixed with 300 g of palm oil, 300 g of coconut oil, and 200 g of castor oil. When the mixture is thick, wrap the top with vinyl, seal it with rubber band and heat it. Add 164 g of glycerin and 278 g of alcohol to the solution and stir well. 4 g of the composition 1 of Example 1 was added to the solution, and the mixture was heated with a water bath for about 30 minutes. After adjusting the pH of the soap with stearic acid, 135 g of sugar is dissolved in 52 g of hot water and added. After adding 8g of pigment and 8g of essential oil, pour it into a soap mold to solidify for more than 24 hours, cut it into a suitable size, and use it after drying for 2-3 weeks.

Soap was prepared in the same manner using 0.8 g, 0.4 g, 0.4 g and 0.4 g of Composition 2 and Composition 3, Composition 4 and Composition 5 instead of Composition 1.

In addition, placebo soaps containing the same amount of ingredients except for the composition for activity evaluation were also prepared and used for evaluation of the composition.

Example 3. Tonic Preparation Using Composition

Tonic was prepared as shown in Table 2 utilizing the composition of the present invention. Ascorbic acid of the included components when used with the composition of the present invention serves to improve the efficacy. When preparing a tonic utilizing the composition, a solution of ethanol mixed with purified water was added and the remaining ingredients were mixed until completely dissolved.

Ingredient (% by weight) Placebo Tonic Composition 1 Added Tonic Composition 2 Added Tonic Composition 3 Added Tonic Composition 4 Added Tonic Composition 5 Added Tonic ethanol 50.00 50.00 50.00 50.00 50.00 50.00 Composition - 3.00 0.60 0.30 0.30 0.30 glycerin 3.00 3.00 3.00 3.00 3.00 3.00 Salicylic acid 0.05 0.05 0.05 0.05 0.05 0.05 menthol 0.02 0.02 0.02 0.02 0.02 0.02 Ascorbic Acid 0.03 0.03 0.03 0.03 0.03 0.03 1,2-hexanediol 0.03 0.03 0.03 0.03 0.03 0.03 Yellow Lotus Root Extract 0.03 0.03 0.03 0.03 0.03 0.03 Green Tea Extract 0.02 0.02 0.02 0.02 0.02 0.02 Purified water 46.82 43.82 46.32 46.52 46.52 46.52 Total 100.00 100.00 100.00 100.00 100.00 100.00

Example 4. Preparation of Shampoo Using Compositions

Using the composition of the present invention to prepare a shampoo as shown in Table 3. Ascorbic acid of the included components when used with the composition of the present invention serves to improve the efficacy. When preparing a shampoo using the composition was prepared by mixing the remaining components except the oil in purified water until completely dissolved. Thereafter, two kinds of oils were mixed until completely mixed to prepare a shampoo.

Ingredient Name (wt%) Placebo shampoo Composition 1 Additive Shampoo Composition 2 Additive Shampoo Composition 3 Additive Shampoo Composition 4 Additive Shampoo Composition 5 addition shampoo Purified water 51.82 50.32 51.52 51.67 51.67 51.67 Composition - 1.50 0.30 0.15 0.15 0.15 Olive surfactant 34.50 34.50 34.50 34.50 34.50 34.50 Cocobetaine 10.30 10.30 10.30 10.30 10.30 10.30 Poly quarter 0.30 0.30 0.30 0.30 0.30 0.30 glycerin 1.70 1.70 1.70 1.70 1.70 1.70 Natural Vitamin E 0.30 0.30 0.30 0.30 0.30 0.30 Ascorbic Acid 0.03 0.03 0.03 0.03 0.03 0.03 Grapefruit Seed Extract 0.30 0.30 0.30 0.30 0.30 0.30 Dipanthenol (Provitamin B5) 0.70 0.70 0.70 0.70 0.70 0.70 1,2-hexanediol 0.03 0.03 0.03 0.03 0.03 0.03 Citrix Acid 0.01 0.01 0.01 0.01 0.01 0.01 Niacinamide 0.01 0.01 0.01 0.01 0.01 0.01 Total 100.00 100.00 100.00 100.00 100.00 100.00 Tea Tree Essential Oil 2drops 2drops 2drops 2drops 2drops 2drops Peppermint Essential Oil 2drops 2drops 2drops 2drops 2drops 2drops

Example 5 Activity Evaluation Experiments of Products Containing Compositions 1-5

5-1: Evaluation of the color improving effect at the hair generating site

Evaluation of the color improving effect of the newly generated hair was carried out for the products of Examples 2, 3 and 4 containing Compositions 1 to 5 as follows.

Visually, 12 male subjects with hair loss of 20% or more are allowed to use the product for 4 weeks, and a total of 30 bleached hairs before and after use are randomly selected from each of the left, right and parietal parts of the head. By comparison. Before and after using the product, photographs were compared, and among the 30 decolored hairs, the darker portion of the hair near the scalp was recorded. The number of hairs that appeared darker at the bottom was recorded by comparing the degree of darkness from the scalp along the length of 1 cm along the hair length. Haircuts were not allowed during the 4-week trial period. The results of the evaluation are shown in Table 4 and FIGS. 1 to 3.

Before use 4 weeks after use % Improvement Composition 1 Add Soap 1.3 4.7 262 Composition 2 Add Soap 1.8 5.1 283 Composition 1 Additive Shampoo 2.2 5.3 141 Composition 3 Additive Shampoo 1.5 8.3 453 Composition 4 Additive Shampoo 1.6 8.0 500 Composition 5 addition shampoo 1.5 7.4 493 Tonic with the addition of composition 3 1.2 10.7 792 Tonic with the addition of composition 4 1.1 9.9 900 Tonic with the addition of composition 5 1.4 11.4 814 Placebo soap 1.4 1.3 -7 Placebo shampoo 2.0 2.2 10 Placebo Tonic 1.7 1.5 -12

5-2: Evaluation of Satisfaction for Improving Overall Hair Color

About the products of Examples 2, 3 and 4 containing Compositions 1 to 5, the degree of hair color improvement by visual observation was performed as follows.

For 24 to 20-70-year-old males with cosmetic problems due to their usual gray hair, use the product containing the composition of the present invention for 4 weeks and subjective satisfaction with the degree of cosmetic improvement after use 1 (not improved) The scales were 2 (slightly improved), 3 (slightly improved), 4 (significantly improved), and 5 (satisfactoryly improved). The results of the evaluation are shown in Table 5. The results showed greater satisfaction in all products compared to placebo, and higher satisfaction was achieved when soap or shampoo and tonic were used simultaneously.

Satisfaction (1 ~ 5) Composition 1 Add Soap 3 Composition 2 Add Soap 3 Composition 1 Additive Shampoo 2 Composition 3 Additive Shampoo 4 Composition 4 Additive Shampoo 4 Composition 5 addition shampoo 4 Tonic with the addition of composition 3 5 Tonic with the addition of composition 4 5 Tonic with the addition of composition 5 5 Placebo soap One Placebo shampoo One Placebo Tonic One

5-3: Comparing Photos of Overall Hair Color Change

For the products of Examples 2, 3, and 4 containing Compositions 1 to 5, hair color improvement was compared by before and after photography, and the results are shown in FIGS. 4 to 6. According to the figure it can be seen that the gray hair is improved when using the product comprising the phlorotannin composition of the present invention. That is, gray hair production was prevented and black hair production was promoted.

Claims (15)

delete Phlorotannin of the formula (4); And at least one phlorotannin selected from Chemical Formulas 2, 5, and 8 as an active ingredient.
[Formula 2]

[Formula 4]

[Formula 5]

[Formula 8]

The composition for preventing white hair and promoting black hair according to claim 2, wherein the composition comprises 20-100% by weight of total phlorotannin. The method of claim 2, further comprising at least one phlorotannin selected from the compounds represented by the following formula (1), (3), (6), (7), (9), (10), (11) and (12). Anti-white hair and composition for promoting black hair
[Formula 1]

[Formula 3]

[Formula 6]

[Formula 7]

[Formula 9]

[Formula 10]

[Formula 11]

[Formula 12]

The composition according to claim 2, wherein the composition is 1-60% by weight of fluorotannin of Formula 2, 0.3-20% by weight of fluorotannin of Formula 4, 0.1-10% by weight of fluorotannin of Formula 5, and fluorotannin of Formula 8 White hair prevention and black hair promoting composition, characterized in that it comprises 0.1-5% by weight The composition of claim 2, wherein the composition comprises 1-65% by weight of phlorotannin of Formula 2, and 0.3-45% by weight of phlorotannin of Formula 4. delete The composition according to claim 4, wherein the composition is 0.1 to 3% by weight of fluorotannin of Formula 1, 5 to 63% by weight of fluorotannin of Formula 2, 1 to 3% by weight of fluorotannin of Formula 3, and fluorotannin of Formula 4 0.5 to 34% by weight, 0.1 to 50% by weight of phlorotannin of formula 5, 0.5 to 8% by weight of phlorotannin of formula 6, 0.1 to 1% by weight of phlorotannin of formula 7, 0.1 to 1% to phlorotannin of formula 8 46% by weight, 0.1-2% by weight of fluorotannin of formula 9, 0.1-7% by weight of fluorotannin of formula 10, 0.1-3% by weight of fluorotannin of formula 11 and 0.1-4% by weight of fluorotannin of formula 12 Composition for preventing white hair and promoting black hair, characterized in that it comprises% The method according to claim 3, 20 to 100% by weight of phlorotannin, 0 to 30% by weight of mannitol, 0 to 25% by weight of alginic acid, 0 to 25% by weight of fucoidan, 0 to 10% by weight of fucosterol, 0 to 10% by weight of fucoxanthin , Lamina is 0 to 10% by weight composition for preventing white hair and black hair, characterized in that it comprises According to claim 3, 20 to 97% by weight of phlorotannin, 1 to 30% by weight of mannitol, 1 to 25% by weight of alginic acid, 0.5 to 25% by weight of fucoidan, 0.1 to 10% by weight of fucosterol, 0.1 to 10% by weight of fucoxanthin , Lamina is a composition for preventing white hair and promoting black hair, characterized in that it comprises 0.1 to 10% by weight The method according to claim 2, wherein the phlorotannin compound is Eisenia bicyclis, Eisenia arborea, Eisenia desmarestioides, Eisenia galapagensis, Eisenia masonii, Ecklonia kurome, Ecklonia cava, Ecklonia stolonifera, Ecklonia maxima, Eclonia radiata, Eclonia bicyclis Ecklonia bicyclis, Eclonia biruncinate, Eclonia buccinalis, Eclonia caepaestipes, Eclonia exasperta, Eclonia pasta Ecklonia fastigiata, Eclonia brevipes, Eclonia arborea, Eclonia latifolia, Eclonia Murati Lonia muratii, Eclonia radicosa, Eclonia richardiana, and Eclonia wrightii Composition Anti-white hair and black hair promoting product comprising the composition of claim 2 The product for preventing white hair and promoting black hair according to claim 12, wherein the product is in a soap, shampoo or tonic form. The method for preventing white hair and promoting black hair according to claim 12, wherein the phlorotannin is contained in an amount of 0.01 to 5% by weight based on the total weight of the product. The product for preventing white hair and promoting black hair according to claim 12, wherein the composition is used at a concentration of 0.1 to 50 mg per day.

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