KR102049978B1 - Nkx3.2 단편을 유효성분으로 포함하는 관절염의 예방 또는 치료용 약학 조성물 - Google Patents

Nkx3.2 단편을 유효성분으로 포함하는 관절염의 예방 또는 치료용 약학 조성물 Download PDF

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KR102049978B1
KR102049978B1 KR1020170148509A KR20170148509A KR102049978B1 KR 102049978 B1 KR102049978 B1 KR 102049978B1 KR 1020170148509 A KR1020170148509 A KR 1020170148509A KR 20170148509 A KR20170148509 A KR 20170148509A KR 102049978 B1 KR102049978 B1 KR 102049978B1
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KR20180052104A (ko
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김대원
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아이씨엠 주식회사
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y10S514/825—

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Molecular Biology (AREA)
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  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020170148509A 2016-11-09 2017-11-09 Nkx3.2 단편을 유효성분으로 포함하는 관절염의 예방 또는 치료용 약학 조성물 Active KR102049978B1 (ko)

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KR20160149090 2016-11-09
KR1020160149090 2016-11-09

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KR20180052104A KR20180052104A (ko) 2018-05-17
KR102049978B1 true KR102049978B1 (ko) 2019-11-28

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KR1020170148509A Active KR102049978B1 (ko) 2016-11-09 2017-11-09 Nkx3.2 단편을 유효성분으로 포함하는 관절염의 예방 또는 치료용 약학 조성물
KR1020170148493A Active KR102049987B1 (ko) 2016-11-09 2017-11-09 Nkx3.2 단편 및 이를 함유하는 약학 조성물
KR1020190140236A Active KR102340761B1 (ko) 2016-11-09 2019-11-05 Nkx3.2 단편 및 이를 함유하는 약학 조성물
KR1020200144613A Active KR102342171B1 (ko) 2016-11-09 2020-11-02 Nkx3.2 단편 및 이를 함유하는 약학 조성물

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KR1020170148493A Active KR102049987B1 (ko) 2016-11-09 2017-11-09 Nkx3.2 단편 및 이를 함유하는 약학 조성물
KR1020190140236A Active KR102340761B1 (ko) 2016-11-09 2019-11-05 Nkx3.2 단편 및 이를 함유하는 약학 조성물
KR1020200144613A Active KR102342171B1 (ko) 2016-11-09 2020-11-02 Nkx3.2 단편 및 이를 함유하는 약학 조성물

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US (2) US11235025B2 (enExample)
EP (2) EP3835311B1 (enExample)
JP (2) JP6991593B2 (enExample)
KR (4) KR102049978B1 (enExample)
CN (2) CN115925865A (enExample)
AU (2) AU2017358282C1 (enExample)
CA (1) CA3042186C (enExample)
ES (2) ES3009014T3 (enExample)
WO (1) WO2018088813A2 (enExample)

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FR3060947B1 (fr) * 2016-12-28 2025-12-26 Ynsect Procede de traitement d'insectes comprenant la separation des cuticules de la partie molle des insectes puis la separation de la partie molle en trois fractions
CA3112915A1 (en) 2018-10-19 2020-04-23 Icm Co., Ltd. Pharmaceutical composition for treating retinal diseases, comprising nkx3.2 and fragment thereof as active ingredients
KR102336515B1 (ko) * 2018-10-25 2021-12-07 애니젠 주식회사 부포린 유도체 및 이의 용도
CN112409454B (zh) * 2020-11-04 2022-07-05 青岛农业大学 一种法氏囊七肽及其制备方法和应用

Citations (1)

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WO2012097057A2 (en) * 2011-01-11 2012-07-19 Tufts University Methods, compositions and kits for modulating trans-differentiation of muscle satellite cells

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US4797368A (en) 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
JP5996429B2 (ja) * 2009-09-03 2016-09-21 ジェネンテック， インコーポレイテッド 関節リウマチの治療、診断及びモニターするための方法
KR101150900B1 (ko) * 2010-01-26 2012-05-30 연세대학교 산학협력단 퇴행성 관절염 치료 조성물
WO2011093647A2 (en) * 2010-01-26 2011-08-04 Industry-Academic Cooperation Foundation, Yonsei University Genes implicated in osteoarthritis and use thereof
KR101150990B1 (ko) 2010-06-19 2012-06-13 김유정 슬롯리스 고정자를 갖는 브러시리스 직류 모터
UY35368A (es) * 2013-03-08 2014-10-31 Irm Llc Péptidos y composiciones para el tratamiento de daño articular
AU2014310360B2 (en) * 2013-06-11 2019-10-24 PPL (BVI) Limited Structure, manufacturing and uses of human-derived cell-permeable peptides conjugated with specific biologically active cargo peptides
KR102044530B1 (ko) * 2017-04-21 2019-11-14 아이씨엠 주식회사 Nkx3.2 및 이의 단편을 유효성분으로 포함하는 망막질환 치료용 약학적 조성물

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012097057A2 (en) * 2011-01-11 2012-07-19 Tufts University Methods, compositions and kits for modulating trans-differentiation of muscle satellite cells
US20140004047A1 (en) 2011-01-11 2014-01-02 Tufts University Methods, compositions and kits for modulating trans-differentiation of muscle satellite cells

Non-Patent Citations (2)

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Title
NCBI Reference Sequence: XP_011839517.1 (2015. 3.30.)*
NCBI Reference Sequence: XP_011839517.1 (2015. 3.30.)]*

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Publication number Publication date
EP3539978A2 (en) 2019-09-18
EP3835311B1 (en) 2024-08-28
ES3009014T3 (en) 2025-03-25
EP3539978C0 (en) 2025-02-26
AU2017358282B2 (en) 2020-07-30
WO2018088813A3 (ko) 2018-10-04
JP2019535310A (ja) 2019-12-12
US11235025B2 (en) 2022-02-01
AU2017358282C1 (en) 2020-11-26
EP3835311C0 (en) 2024-08-28
JP6991593B2 (ja) 2022-01-12
EP3835311A1 (en) 2021-06-16
EP3539978A4 (en) 2020-08-05
KR102049987B1 (ko) 2019-11-28
CN110036023B (zh) 2023-01-10
KR20190126753A (ko) 2019-11-12
KR20200129068A (ko) 2020-11-17
US20200188480A1 (en) 2020-06-18
WO2018088813A2 (ko) 2018-05-17
CN115925865A (zh) 2023-04-07
JP2021020962A (ja) 2021-02-18
KR20180052103A (ko) 2018-05-17
AU2020207879A1 (en) 2020-08-13
CA3042186A1 (en) 2018-05-17
CN110036023A (zh) 2019-07-19
AU2017358282A1 (en) 2019-05-23
US11154590B2 (en) 2021-10-26
CA3042186C (en) 2021-06-15
KR102342171B1 (ko) 2021-12-23
AU2020207879B2 (en) 2021-04-15
JP7055455B2 (ja) 2022-04-18
KR20180052104A (ko) 2018-05-17
ES2987020T3 (es) 2024-11-13
WO2018088813A9 (ko) 2018-11-15
EP3539978B1 (en) 2025-02-26
US20190351015A1 (en) 2019-11-21
KR102340761B1 (ko) 2021-12-21

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