KR101940357B1 - 세포 표면 상 etec cs6 항원 제시의 증가 방법 및 그것의 수득가능한 산물들 - Google Patents

세포 표면 상 etec cs6 항원 제시의 증가 방법 및 그것의 수득가능한 산물들 Download PDF

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KR101940357B1
KR101940357B1 KR1020147009747A KR20147009747A KR101940357B1 KR 101940357 B1 KR101940357 B1 KR 101940357B1 KR 1020147009747 A KR1020147009747 A KR 1020147009747A KR 20147009747 A KR20147009747 A KR 20147009747A KR 101940357 B1 KR101940357 B1 KR 101940357B1
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antigen
cells
etec
presentation
phenol
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KR1020147009747A
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KR20140068187A (ko
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닐스 칼린
앤-마리 스베너홈
요슈아 토비아스
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스칸디나비안 바이오파마 홀딩 에이비
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0258Escherichia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001102Receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07KPEPTIDES
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    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
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    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
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    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56916Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Tropical Medicine & Parasitology (AREA)
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  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020147009747A 2011-09-12 2012-09-10 세포 표면 상 etec cs6 항원 제시의 증가 방법 및 그것의 수득가능한 산물들 KR101940357B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161533405P 2011-09-12 2011-09-12
US61/533,405 2011-09-12
SE1150821 2011-09-12
SE1150821-5 2011-09-12
PCT/EP2012/067598 WO2013037718A1 (en) 2011-09-12 2012-09-10 Method for increasing etec cs6 antigen presentation on cell surface and products obtainable thereof

Publications (2)

Publication Number Publication Date
KR20140068187A KR20140068187A (ko) 2014-06-05
KR101940357B1 true KR101940357B1 (ko) 2019-01-18

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KR1020147009747A KR101940357B1 (ko) 2011-09-12 2012-09-10 세포 표면 상 etec cs6 항원 제시의 증가 방법 및 그것의 수득가능한 산물들

Country Status (15)

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US (6) US9273103B2 (ru)
EP (1) EP2750701B1 (ru)
JP (1) JP5985643B2 (ru)
KR (1) KR101940357B1 (ru)
CN (1) CN103917244B (ru)
AU (1) AU2012307540B2 (ru)
BR (1) BR112014005596B1 (ru)
CA (1) CA2846279C (ru)
DK (1) DK2750701T3 (ru)
ES (1) ES2558454T3 (ru)
HK (1) HK1199210A1 (ru)
PL (1) PL2750701T3 (ru)
PT (1) PT2750701E (ru)
RU (1) RU2628698C2 (ru)
WO (1) WO2013037718A1 (ru)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112014005596B1 (pt) * 2011-09-12 2020-03-24 Scandinavian Biopharma Holding Ab Método para aumentar a apresentação de antígeno cs6 de etec na superfície da célula, método para a fabricação de uma vacina de célula inteira morta, e, vacina para a imunização contra etec que expressa cs6

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005504002A (ja) 2001-02-13 2005-02-10 ガバメント オブ ザ ユナイテッド ステイツ、 アズ リプリゼンティッド バイ ザ セクレタリィ オブ ジ アーミイ 経皮免疫感作のためのワクチン
WO2007089205A1 (en) 2006-02-01 2007-08-09 Sbl Vaccin Ab Colonization factor (cf) antigens of enterotoxigenic escherichia coli in recombinant bacteria

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SE9100556D0 (sv) * 1991-02-26 1991-02-26 Holmgren Jan Preparation and use of formalin-killed colonization-factor-antigen (cfa)-expressing e coli organisms for vaccination against enteric infection/diarrhea caused by enterotoxigenic e coli bacteria in humans
JPH11512746A (ja) * 1995-10-05 1999-11-02 イミユセル・コーポレーシヨン 乳漿中の免疫グロブリンの単離方法
US20020034522A1 (en) * 1998-03-13 2002-03-21 Flynn, Thiel, Boutell, And Tanis, P.C. Use of a strain of pasteurella haemolytica of a particular serotype for preparing a vaccine against bovine pasteurellosis due to pasteurella haemolytica
SE515285C2 (sv) * 1998-12-18 2001-07-09 Sbl Vaccin Ab Oralt vaccin mot diarré
GB0121998D0 (en) * 2001-09-11 2001-10-31 Acambis Res Ltd Attenuated bacteria useful in vaccines
EP1481053B1 (en) * 2002-02-25 2007-09-12 US Army Medical Research & Materiel Command Method of making cs6 antigen vaccine for treating, preventing, or inhibiting enterotoxigenic escherichia coli infections
RU2242993C2 (ru) * 2002-11-18 2004-12-27 Федеральное государственное унитарное предприятие Пермское научно-производственное объединение "Биомед" Способ приготовления вакцины для профилактики хламидийных инфекций у человека
BR112014005601B1 (pt) * 2011-09-12 2020-09-29 Scandinavian Biopharma Holding Ab Vacina oral para a imunização contra a diarréia induzida pela etec
BR112014005596B1 (pt) * 2011-09-12 2020-03-24 Scandinavian Biopharma Holding Ab Método para aumentar a apresentação de antígeno cs6 de etec na superfície da célula, método para a fabricação de uma vacina de célula inteira morta, e, vacina para a imunização contra etec que expressa cs6

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005504002A (ja) 2001-02-13 2005-02-10 ガバメント オブ ザ ユナイテッド ステイツ、 アズ リプリゼンティッド バイ ザ セクレタリィ オブ ジ アーミイ 経皮免疫感作のためのワクチン
JP2010180228A (ja) 2001-02-13 2010-08-19 Government Of The United States Of America As Represented By The Secretary Of The Army 経皮免疫感作のためのワクチン
WO2007089205A1 (en) 2006-02-01 2007-08-09 Sbl Vaccin Ab Colonization factor (cf) antigens of enterotoxigenic escherichia coli in recombinant bacteria

Non-Patent Citations (1)

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Title
Vaccine, (2010.10.)Vol. 28, No. 43, pp6977-6984.

Also Published As

Publication number Publication date
BR112014005596A2 (pt) 2017-04-04
WO2013037718A1 (en) 2013-03-21
CA2846279A1 (en) 2013-03-21
HK1199210A1 (zh) 2015-06-26
US9273103B2 (en) 2016-03-01
EP2750701B1 (en) 2015-10-21
RU2628698C2 (ru) 2017-08-21
BR112014005596B1 (pt) 2020-03-24
KR20140068187A (ko) 2014-06-05
US20240140996A1 (en) 2024-05-02
EP2750701A1 (en) 2014-07-09
CN103917244B (zh) 2016-07-06
PT2750701E (pt) 2016-02-01
CA2846279C (en) 2021-05-18
RU2014114284A (ru) 2015-10-20
AU2012307540A1 (en) 2014-02-27
US20210147491A1 (en) 2021-05-20
US10414806B2 (en) 2019-09-17
ES2558454T3 (es) 2016-02-04
US9790257B2 (en) 2017-10-17
US10851140B2 (en) 2020-12-01
US20160251401A1 (en) 2016-09-01
US20190389913A1 (en) 2019-12-26
CN103917244A (zh) 2014-07-09
PL2750701T3 (pl) 2016-03-31
JP2014531428A (ja) 2014-11-27
AU2012307540B2 (en) 2016-09-22
US20140178436A1 (en) 2014-06-26
US11820798B2 (en) 2023-11-21
DK2750701T3 (en) 2016-01-11
US20180079787A1 (en) 2018-03-22
JP5985643B2 (ja) 2016-09-06

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