KR101919269B1 - 데옥시콜린산 및 그의 염들의 제형물들 - Google Patents

데옥시콜린산 및 그의 염들의 제형물들 Download PDF

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Publication number
KR101919269B1
KR101919269B1 KR1020177016779A KR20177016779A KR101919269B1 KR 101919269 B1 KR101919269 B1 KR 101919269B1 KR 1020177016779 A KR1020177016779 A KR 1020177016779A KR 20177016779 A KR20177016779 A KR 20177016779A KR 101919269 B1 KR101919269 B1 KR 101919269B1
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KR
South Korea
Prior art keywords
sodium deoxycholate
aqueous solution
sodium
deoxycholic acid
solution
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KR1020177016779A
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English (en)
Korean (ko)
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KR20170075016A (ko
Inventor
로버트 에밀 호지
제프리 더글라스 웹스터
로버트 엠. 모리어티
Original Assignee
키쎄라 바이오파마슈티컬즈 인코포레이티드
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Application filed by 키쎄라 바이오파마슈티컬즈 인코포레이티드 filed Critical 키쎄라 바이오파마슈티컬즈 인코포레이티드
Publication of KR20170075016A publication Critical patent/KR20170075016A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
KR1020177016779A 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들 KR101919269B1 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/048806 WO2013028177A1 (en) 2011-08-23 2011-08-23 Formulations of deoxycholic acid and salts thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020147006855A Division KR101751585B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020187032491A Division KR102034606B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Publications (2)

Publication Number Publication Date
KR20170075016A KR20170075016A (ko) 2017-06-30
KR101919269B1 true KR101919269B1 (ko) 2018-11-15

Family

ID=45569726

Family Applications (5)

Application Number Title Priority Date Filing Date
KR1020197030233A KR102073536B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020147006855A KR101751585B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020187032491A KR102034606B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020177016779A KR101919269B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020207002722A KR20200013103A (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Family Applications Before (3)

Application Number Title Priority Date Filing Date
KR1020197030233A KR102073536B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020147006855A KR101751585B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020187032491A KR102034606B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020207002722A KR20200013103A (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Country Status (18)

Country Link
JP (1) JP5919597B2 (es)
KR (5) KR102073536B1 (es)
CN (3) CN108743522A (es)
AU (3) AU2011375432B2 (es)
BR (1) BR112014000547B1 (es)
CA (1) CA2842177C (es)
CR (1) CR20140053A (es)
EA (1) EA029305B1 (es)
IL (1) IL230547A (es)
IN (1) IN2014CN02188A (es)
MX (1) MX350390B (es)
MY (1) MY184277A (es)
NZ (1) NZ620040A (es)
PH (1) PH12016501175B1 (es)
SG (1) SG2014013205A (es)
UA (1) UA113522C2 (es)
WO (1) WO2013028177A1 (es)
ZA (1) ZA201401027B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102111346B1 (ko) 2019-08-20 2020-05-22 아영창 침전으로부터 안정한 소듐디옥시콜레이트를 포함하는 수용액상 조성물

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
KR20180100309A (ko) * 2015-11-04 2018-09-10 키쎄라 바이오파마슈티컬즈 인코포레이티드 데옥시콜산 및 이의 염을 사용한 축적된 지방의 치료 방법
KR101841193B1 (ko) * 2016-09-22 2018-03-22 이경락 저장성 지방 분해 조성물 및 그의 제조 방법
US20180078621A1 (en) * 2016-09-22 2018-03-22 Kyoung Lack Lee Composition for hypotonic lipolysis and manufacturing method thereof
BR112020019192A2 (pt) * 2018-04-16 2021-01-05 Penmix Ltd. Composição farmacêutica que compreende ácido deoxicólico
KR102172439B1 (ko) * 2018-12-05 2020-10-30 송미희 지방 분해용 조성물 및 이를 포함하는 주사제 조성물
KR102064864B1 (ko) 2019-02-08 2020-01-10 (주)제테마 국소 주사용 조성물
KR20220026068A (ko) 2020-08-25 2022-03-04 강명범 지방 분해용 주사제 조성물
CN116617160A (zh) * 2023-07-25 2023-08-22 山东则正医药技术有限公司 水性混悬液及制备方法、冻干粉及应用、脂肪消减注射剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417179B1 (en) 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution

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FR2754709B1 (fr) 1996-10-23 1999-03-05 Sanofi Sa Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition
JP4790123B2 (ja) * 1998-07-24 2011-10-12 ヨー、セオ、ホン 胆汁酸を有する透明水溶液型製剤の調剤
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
DE10361067A1 (de) * 2003-12-22 2005-07-14 Aventis Pharma Deutschland Gmbh Medikamentöse Lipolyse von Fettansammlungen
EP3424508B1 (en) 2004-05-19 2021-05-05 Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center Use of sodium deoxycholate for the removal of localized fat accumulation
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
US7754230B2 (en) * 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
US20090317376A1 (en) 2005-06-06 2009-12-24 Georgetown University Medical School Compositions And Methods For Lipo Modeling
TW201011755A (en) 2008-09-10 2010-03-16 Skymedi Corp Flash memory system and its data recovery method
JP5420946B2 (ja) * 2009-03-23 2014-02-19 富士フイルム株式会社 胆汁酸を含むミノキシジル水性組成物
EP2645099A1 (en) 2012-03-30 2013-10-02 Phares Pharmaceutical Research N.V. Biorelevant compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417179B1 (en) 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Dermatologic Surgery, 2009, 35, 792-803.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102111346B1 (ko) 2019-08-20 2020-05-22 아영창 침전으로부터 안정한 소듐디옥시콜레이트를 포함하는 수용액상 조성물

Also Published As

Publication number Publication date
EA029305B1 (ru) 2018-03-30
JP5919597B2 (ja) 2016-05-18
CA2842177A1 (en) 2013-02-28
KR20170075016A (ko) 2017-06-30
CR20140053A (es) 2014-06-12
IL230547A (en) 2017-02-28
CN108743522A (zh) 2018-11-06
IN2014CN02188A (es) 2015-05-29
CN103826608A (zh) 2014-05-28
MY184277A (en) 2021-03-30
AU2016202661B2 (en) 2018-02-22
AU2011375432A1 (en) 2014-02-06
AU2018202807B2 (en) 2020-01-16
KR102034606B1 (ko) 2019-10-22
PH12016501175A1 (en) 2017-12-11
KR102073536B1 (ko) 2020-02-04
MX350390B (es) 2017-09-06
WO2013028177A1 (en) 2013-02-28
BR112014000547A2 (pt) 2017-02-14
NZ620040A (en) 2016-06-24
UA113522C2 (xx) 2017-02-10
KR20180123734A (ko) 2018-11-19
BR112014000547B1 (pt) 2021-11-09
IL230547A0 (en) 2014-03-31
SG2014013205A (en) 2014-05-29
AU2016202661A1 (en) 2016-05-19
EA201490175A1 (ru) 2014-06-30
MX2014001495A (es) 2014-04-25
AU2011375432B2 (en) 2016-02-04
JP2014524467A (ja) 2014-09-22
AU2018202807A1 (en) 2018-05-10
KR20190119677A (ko) 2019-10-22
ZA201401027B (en) 2017-09-27
PH12016501175B1 (en) 2017-12-11
KR20200013103A (ko) 2020-02-05
KR20150000448A (ko) 2015-01-02
KR101751585B1 (ko) 2017-06-27
CN108619089A (zh) 2018-10-09
CA2842177C (en) 2016-07-19

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