MX2014001495A - Formulaciones de acido desoxicolico y sales del mismo. - Google Patents
Formulaciones de acido desoxicolico y sales del mismo.Info
- Publication number
- MX2014001495A MX2014001495A MX2014001495A MX2014001495A MX2014001495A MX 2014001495 A MX2014001495 A MX 2014001495A MX 2014001495 A MX2014001495 A MX 2014001495A MX 2014001495 A MX2014001495 A MX 2014001495A MX 2014001495 A MX2014001495 A MX 2014001495A
- Authority
- MX
- Mexico
- Prior art keywords
- deoxycholic acid
- formulations
- salts
- composition
- salt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
La presente invención se refiere a una composición farmacéutica acuosa que comprende desde aproximadamente 0.4% en p/v a menos de aproximadamente 2% en p/v de una sal de ácido desoxicólico, en donde la composición se mantiene a un pH desde aproximadamente 8.1 hasta aproximadamente 8.5 de manera que la composición es estabilizada contra la precipitación. También descritos en la presente, están métodos para estabilizar una composición farmacéutica acuosa que comprende desde aproximadamente 0.4% en p/v a menos de aproximadamente 2% en p/v de una sal de ácido desoxicólico contra la precipitación, tal método comprende mantener el pH de la solución desde aproximadamente 8.1 hasta aproximadamente 8.5.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2011/048806 WO2013028177A1 (en) | 2011-08-23 | 2011-08-23 | Formulations of deoxycholic acid and salts thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014001495A true MX2014001495A (es) | 2014-04-25 |
MX350390B MX350390B (es) | 2017-09-06 |
Family
ID=45569726
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014001495A MX350390B (es) | 2011-08-23 | 2011-08-23 | Formulaciones de acido desoxicolico y sales del mismo. |
Country Status (18)
Country | Link |
---|---|
JP (1) | JP5919597B2 (es) |
KR (5) | KR20200013103A (es) |
CN (3) | CN108619089A (es) |
AU (3) | AU2011375432B2 (es) |
BR (1) | BR112014000547B1 (es) |
CA (1) | CA2842177C (es) |
CR (1) | CR20140053A (es) |
EA (1) | EA029305B1 (es) |
IL (1) | IL230547A (es) |
IN (1) | IN2014CN02188A (es) |
MX (1) | MX350390B (es) |
MY (1) | MY184277A (es) |
NZ (1) | NZ620040A (es) |
PH (1) | PH12016501175A1 (es) |
SG (1) | SG2014013205A (es) |
UA (1) | UA113522C2 (es) |
WO (1) | WO2013028177A1 (es) |
ZA (1) | ZA201401027B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
JP2018532806A (ja) * | 2015-11-04 | 2018-11-08 | キセラ バイオファーマシューティカルズ インコーポレイテッド | デオキシコール酸およびその塩による蓄積脂肪の処置方法 |
US20180078621A1 (en) * | 2016-09-22 | 2018-03-22 | Kyoung Lack Lee | Composition for hypotonic lipolysis and manufacturing method thereof |
KR101841193B1 (ko) * | 2016-09-22 | 2018-03-22 | 이경락 | 저장성 지방 분해 조성물 및 그의 제조 방법 |
US20190314388A1 (en) * | 2018-04-16 | 2019-10-17 | Penmix Ltd. | Pharmaceutical composition containing deoxycholic acid |
KR102172439B1 (ko) | 2018-12-05 | 2020-10-30 | 송미희 | 지방 분해용 조성물 및 이를 포함하는 주사제 조성물 |
KR102064864B1 (ko) | 2019-02-08 | 2020-01-10 | (주)제테마 | 국소 주사용 조성물 |
KR102111346B1 (ko) * | 2019-08-20 | 2020-05-22 | 아영창 | 침전으로부터 안정한 소듐디옥시콜레이트를 포함하는 수용액상 조성물 |
KR20220026068A (ko) | 2020-08-25 | 2022-03-04 | 강명범 | 지방 분해용 주사제 조성물 |
CN116617160A (zh) * | 2023-07-25 | 2023-08-22 | 山东则正医药技术有限公司 | 水性混悬液及制备方法、冻干粉及应用、脂肪消减注射剂 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2754709B1 (fr) | 1996-10-23 | 1999-03-05 | Sanofi Sa | Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition |
EP1113785B1 (en) * | 1998-07-24 | 2005-04-13 | Seo Hong Yoo | Clear aqueous solutions of bile acids |
US6417179B1 (en) * | 1998-10-13 | 2002-07-09 | Craig G. Burkhart | Ear wax solution |
US20050048126A1 (en) * | 2000-12-22 | 2005-03-03 | Barrett Rabinow | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
DE10361067A1 (de) * | 2003-12-22 | 2005-07-14 | Aventis Pharma Deutschland Gmbh | Medikamentöse Lipolyse von Fettansammlungen |
US7754230B2 (en) * | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
HUE038247T2 (hu) * | 2004-05-19 | 2018-10-29 | Los Angeles Biomedical Res Inst Harbor Ucla Medical Ct | Nátrium-deoxikolátot tartalmazó injektálható készítmény |
US20060127468A1 (en) * | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
ATE550031T1 (de) | 2005-06-06 | 2012-04-15 | Univ Georgetown | Zusammensetzungen und verfahren für die lipomodellierung |
TW201011755A (en) | 2008-09-10 | 2010-03-16 | Skymedi Corp | Flash memory system and its data recovery method |
JP5420946B2 (ja) * | 2009-03-23 | 2014-02-19 | 富士フイルム株式会社 | 胆汁酸を含むミノキシジル水性組成物 |
EP2645099A1 (en) | 2012-03-30 | 2013-10-02 | Phares Pharmaceutical Research N.V. | Biorelevant compositions |
-
2011
- 2011-08-23 CN CN201810400642.9A patent/CN108619089A/zh active Pending
- 2011-08-23 EA EA201490175A patent/EA029305B1/ru unknown
- 2011-08-23 KR KR1020207002722A patent/KR20200013103A/ko not_active Application Discontinuation
- 2011-08-23 UA UAA201400641A patent/UA113522C2/uk unknown
- 2011-08-23 CN CN201180072842.2A patent/CN103826608A/zh active Pending
- 2011-08-23 SG SG2014013205A patent/SG2014013205A/en unknown
- 2011-08-23 KR KR1020187032491A patent/KR102034606B1/ko active IP Right Grant
- 2011-08-23 CA CA2842177A patent/CA2842177C/en active Active
- 2011-08-23 KR KR1020147006855A patent/KR101751585B1/ko active IP Right Review Request
- 2011-08-23 NZ NZ620040A patent/NZ620040A/en not_active IP Right Cessation
- 2011-08-23 KR KR1020177016779A patent/KR101919269B1/ko active IP Right Grant
- 2011-08-23 AU AU2011375432A patent/AU2011375432B2/en active Active
- 2011-08-23 WO PCT/US2011/048806 patent/WO2013028177A1/en active Application Filing
- 2011-08-23 BR BR112014000547-8A patent/BR112014000547B1/pt active IP Right Grant
- 2011-08-23 MY MYPI2014000197A patent/MY184277A/en unknown
- 2011-08-23 IN IN2188CHN2014 patent/IN2014CN02188A/en unknown
- 2011-08-23 CN CN201810403291.7A patent/CN108743522A/zh active Pending
- 2011-08-23 KR KR1020197030233A patent/KR102073536B1/ko active IP Right Grant
- 2011-08-23 MX MX2014001495A patent/MX350390B/es active IP Right Grant
- 2011-08-23 JP JP2014527128A patent/JP5919597B2/ja active Active
-
2014
- 2014-01-20 IL IL230547A patent/IL230547A/en active IP Right Grant
- 2014-01-30 CR CR20140053A patent/CR20140053A/es unknown
- 2014-02-10 ZA ZA2014/01027A patent/ZA201401027B/en unknown
-
2016
- 2016-04-27 AU AU2016202661A patent/AU2016202661B2/en active Active
- 2016-06-16 PH PH12016501175A patent/PH12016501175A1/en unknown
-
2018
- 2018-04-23 AU AU2018202807A patent/AU2018202807B2/en active Active
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Legal Events
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GD | Licence granted | ||
FG | Grant or registration |