IN2014CN02188A - - Google Patents
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- Publication number
- IN2014CN02188A IN2014CN02188A IN2188CHN2014A IN2014CN02188A IN 2014CN02188 A IN2014CN02188 A IN 2014CN02188A IN 2188CHN2014 A IN2188CHN2014 A IN 2188CHN2014A IN 2014CN02188 A IN2014CN02188 A IN 2014CN02188A
- Authority
- IN
- India
- Prior art keywords
- composition
- salt
- less
- aqueous pharmaceutical
- deoxycholic acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation said method comprising maintaining pH of the solution from about 8.1 to about 8.5.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2011/048806 WO2013028177A1 (en) | 2011-08-23 | 2011-08-23 | Formulations of deoxycholic acid and salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN02188A true IN2014CN02188A (en) | 2015-05-29 |
Family
ID=45569726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2188CHN2014 IN2014CN02188A (en) | 2011-08-23 | 2011-08-23 |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JP5919597B2 (en) |
| KR (5) | KR20200013103A (en) |
| CN (3) | CN108619089A (en) |
| AU (3) | AU2011375432B2 (en) |
| BR (1) | BR112014000547B1 (en) |
| CA (1) | CA2842177C (en) |
| CR (1) | CR20140053A (en) |
| EA (1) | EA029305B1 (en) |
| IL (1) | IL230547A (en) |
| IN (1) | IN2014CN02188A (en) |
| MX (1) | MX350390B (en) |
| MY (1) | MY184277A (en) |
| NZ (1) | NZ620040A (en) |
| PH (1) | PH12016501175A1 (en) |
| SG (1) | SG2014013205A (en) |
| UA (1) | UA113522C2 (en) |
| WO (1) | WO2013028177A1 (en) |
| ZA (1) | ZA201401027B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
| KR20180100309A (en) * | 2015-11-04 | 2018-09-10 | 키쎄라 바이오파마슈티컬즈 인코포레이티드 | Methods for the treatment of accumulated fats using deoxycholic acid and its salts |
| US20180078621A1 (en) * | 2016-09-22 | 2018-03-22 | Kyoung Lack Lee | Composition for hypotonic lipolysis and manufacturing method thereof |
| KR101841193B1 (en) * | 2016-09-22 | 2018-03-22 | 이경락 | Composition for hypotonic lipolysis and manufacturing method thereof |
| US20190314388A1 (en) * | 2018-04-16 | 2019-10-17 | Penmix Ltd. | Pharmaceutical composition containing deoxycholic acid |
| KR102172439B1 (en) | 2018-12-05 | 2020-10-30 | 송미희 | Composition for lipolysis and injection composition comprising the same |
| KR102064864B1 (en) | 2019-02-08 | 2020-01-10 | (주)제테마 | Topical injectable composition |
| KR102111346B1 (en) * | 2019-08-20 | 2020-05-22 | 아영창 | Aqueous composition with sodium deoxycholate having improved stability against precipitation |
| KR20220026068A (en) | 2020-08-25 | 2022-03-04 | 강명범 | Composition for lipolysis and injection composition comprising the same |
| CN116617160A (en) * | 2023-07-25 | 2023-08-22 | 山东则正医药技术有限公司 | Aqueous suspension, preparation method, freeze-dried powder, application and fat reduction injection |
| CN118005707A (en) * | 2024-01-18 | 2024-05-10 | 山东省食品药品检验研究院 | Sodium deoxycholate crystal form A and preparation method and application thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2754709B1 (en) | 1996-10-23 | 1999-03-05 | Sanofi Sa | COSMETIC COMPOSITION CONTAINING AN ANTAGONIST OF GAMMA NEUROPEPTIDE RECEPTORS AND ALPHA 2 ANTAGONISTS THAT MAY BE INCORPORATED IN SUCH A COMPOSITION |
| EP1113785B1 (en) * | 1998-07-24 | 2005-04-13 | Seo Hong Yoo | Clear aqueous solutions of bile acids |
| US6417179B1 (en) * | 1998-10-13 | 2002-07-09 | Craig G. Burkhart | Ear wax solution |
| US20050048126A1 (en) * | 2000-12-22 | 2005-03-03 | Barrett Rabinow | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
| DE10361067A1 (en) * | 2003-12-22 | 2005-07-14 | Aventis Pharma Deutschland Gmbh | Medicinal lipolysis of fat accumulations |
| US7754230B2 (en) * | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
| US20060127468A1 (en) * | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
| ATE521355T1 (en) * | 2004-05-19 | 2011-09-15 | Los Angeles Biomed Res Inst | USE OF A DETERGENT FOR NON-SURGICAL FAT REMOVAL |
| US20090317376A1 (en) | 2005-06-06 | 2009-12-24 | Georgetown University Medical School | Compositions And Methods For Lipo Modeling |
| TW201011755A (en) | 2008-09-10 | 2010-03-16 | Skymedi Corp | Flash memory system and its data recovery method |
| JP5420946B2 (en) * | 2009-03-23 | 2014-02-19 | 富士フイルム株式会社 | Minoxidil aqueous composition containing bile acids |
| EP2645099A1 (en) | 2012-03-30 | 2013-10-02 | Phares Pharmaceutical Research N.V. | Biorelevant compositions |
-
2011
- 2011-08-23 KR KR1020207002722A patent/KR20200013103A/en not_active Application Discontinuation
- 2011-08-23 WO PCT/US2011/048806 patent/WO2013028177A1/en active Application Filing
- 2011-08-23 MY MYPI2014000197A patent/MY184277A/en unknown
- 2011-08-23 JP JP2014527128A patent/JP5919597B2/en active Active
- 2011-08-23 NZ NZ620040A patent/NZ620040A/en not_active IP Right Cessation
- 2011-08-23 KR KR1020197030233A patent/KR102073536B1/en active IP Right Grant
- 2011-08-23 CN CN201810400642.9A patent/CN108619089A/en active Pending
- 2011-08-23 AU AU2011375432A patent/AU2011375432B2/en active Active
- 2011-08-23 KR KR1020177016779A patent/KR101919269B1/en active IP Right Grant
- 2011-08-23 UA UAA201400641A patent/UA113522C2/en unknown
- 2011-08-23 CN CN201810403291.7A patent/CN108743522A/en active Pending
- 2011-08-23 CN CN201180072842.2A patent/CN103826608A/en active Pending
- 2011-08-23 MX MX2014001495A patent/MX350390B/en active IP Right Grant
- 2011-08-23 CA CA2842177A patent/CA2842177C/en active Active
- 2011-08-23 KR KR1020147006855A patent/KR101751585B1/en active IP Right Review Request
- 2011-08-23 IN IN2188CHN2014 patent/IN2014CN02188A/en unknown
- 2011-08-23 KR KR1020187032491A patent/KR102034606B1/en active IP Right Grant
- 2011-08-23 BR BR112014000547-8A patent/BR112014000547B1/en active IP Right Grant
- 2011-08-23 EA EA201490175A patent/EA029305B1/en unknown
- 2011-08-23 SG SG2014013205A patent/SG2014013205A/en unknown
-
2014
- 2014-01-20 IL IL230547A patent/IL230547A/en active IP Right Grant
- 2014-01-30 CR CR20140053A patent/CR20140053A/en unknown
- 2014-02-10 ZA ZA2014/01027A patent/ZA201401027B/en unknown
-
2016
- 2016-04-27 AU AU2016202661A patent/AU2016202661B2/en active Active
- 2016-06-16 PH PH12016501175A patent/PH12016501175A1/en unknown
-
2018
- 2018-04-23 AU AU2018202807A patent/AU2018202807B2/en active Active
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