CA2842177C - Formulations of deoxycholic acid and salts thereof - Google Patents
Formulations of deoxycholic acid and salts thereof Download PDFInfo
- Publication number
- CA2842177C CA2842177C CA2842177A CA2842177A CA2842177C CA 2842177 C CA2842177 C CA 2842177C CA 2842177 A CA2842177 A CA 2842177A CA 2842177 A CA2842177 A CA 2842177A CA 2842177 C CA2842177 C CA 2842177C
- Authority
- CA
- Canada
- Prior art keywords
- aqueous solution
- salt
- deoxycholic acid
- injectable aqueous
- sodium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2011/048806 WO2013028177A1 (en) | 2011-08-23 | 2011-08-23 | Formulations of deoxycholic acid and salts thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2842177A1 CA2842177A1 (en) | 2013-02-28 |
| CA2842177C true CA2842177C (en) | 2016-07-19 |
Family
ID=45569726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2842177A Active CA2842177C (en) | 2011-08-23 | 2011-08-23 | Formulations of deoxycholic acid and salts thereof |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JP5919597B2 (es) |
| KR (5) | KR102073536B1 (es) |
| CN (3) | CN108743522A (es) |
| AU (3) | AU2011375432B2 (es) |
| BR (1) | BR112014000547B1 (es) |
| CA (1) | CA2842177C (es) |
| CR (1) | CR20140053A (es) |
| EA (1) | EA029305B1 (es) |
| IL (1) | IL230547A (es) |
| IN (1) | IN2014CN02188A (es) |
| MX (1) | MX350390B (es) |
| MY (1) | MY184277A (es) |
| NZ (1) | NZ620040A (es) |
| PH (1) | PH12016501175B1 (es) |
| SG (1) | SG2014013205A (es) |
| UA (1) | UA113522C2 (es) |
| WO (1) | WO2013028177A1 (es) |
| ZA (1) | ZA201401027B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
| KR20180100309A (ko) * | 2015-11-04 | 2018-09-10 | 키쎄라 바이오파마슈티컬즈 인코포레이티드 | 데옥시콜산 및 이의 염을 사용한 축적된 지방의 치료 방법 |
| KR101841193B1 (ko) * | 2016-09-22 | 2018-03-22 | 이경락 | 저장성 지방 분해 조성물 및 그의 제조 방법 |
| US20180078621A1 (en) * | 2016-09-22 | 2018-03-22 | Kyoung Lack Lee | Composition for hypotonic lipolysis and manufacturing method thereof |
| BR112020019192A2 (pt) * | 2018-04-16 | 2021-01-05 | Penmix Ltd. | Composição farmacêutica que compreende ácido deoxicólico |
| KR102172439B1 (ko) * | 2018-12-05 | 2020-10-30 | 송미희 | 지방 분해용 조성물 및 이를 포함하는 주사제 조성물 |
| KR102064864B1 (ko) | 2019-02-08 | 2020-01-10 | (주)제테마 | 국소 주사용 조성물 |
| KR102111346B1 (ko) | 2019-08-20 | 2020-05-22 | 아영창 | 침전으로부터 안정한 소듐디옥시콜레이트를 포함하는 수용액상 조성물 |
| KR20220026068A (ko) | 2020-08-25 | 2022-03-04 | 강명범 | 지방 분해용 주사제 조성물 |
| CN116617160A (zh) * | 2023-07-25 | 2023-08-22 | 山东则正医药技术有限公司 | 水性混悬液及制备方法、冻干粉及应用、脂肪消减注射剂 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2754709B1 (fr) | 1996-10-23 | 1999-03-05 | Sanofi Sa | Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition |
| JP4790123B2 (ja) * | 1998-07-24 | 2011-10-12 | ヨー、セオ、ホン | 胆汁酸を有する透明水溶液型製剤の調剤 |
| US6417179B1 (en) * | 1998-10-13 | 2002-07-09 | Craig G. Burkhart | Ear wax solution |
| US20050048126A1 (en) * | 2000-12-22 | 2005-03-03 | Barrett Rabinow | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
| DE10361067A1 (de) * | 2003-12-22 | 2005-07-14 | Aventis Pharma Deutschland Gmbh | Medikamentöse Lipolyse von Fettansammlungen |
| EP3424508B1 (en) | 2004-05-19 | 2021-05-05 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Use of sodium deoxycholate for the removal of localized fat accumulation |
| US20060127468A1 (en) | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
| US7754230B2 (en) * | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
| US20090317376A1 (en) | 2005-06-06 | 2009-12-24 | Georgetown University Medical School | Compositions And Methods For Lipo Modeling |
| TW201011755A (en) | 2008-09-10 | 2010-03-16 | Skymedi Corp | Flash memory system and its data recovery method |
| JP5420946B2 (ja) * | 2009-03-23 | 2014-02-19 | 富士フイルム株式会社 | 胆汁酸を含むミノキシジル水性組成物 |
| EP2645099A1 (en) | 2012-03-30 | 2013-10-02 | Phares Pharmaceutical Research N.V. | Biorelevant compositions |
-
2011
- 2011-08-23 CA CA2842177A patent/CA2842177C/en active Active
- 2011-08-23 KR KR1020197030233A patent/KR102073536B1/ko active IP Right Grant
- 2011-08-23 MX MX2014001495A patent/MX350390B/es active IP Right Grant
- 2011-08-23 CN CN201810403291.7A patent/CN108743522A/zh active Pending
- 2011-08-23 UA UAA201400641A patent/UA113522C2/uk unknown
- 2011-08-23 WO PCT/US2011/048806 patent/WO2013028177A1/en active Application Filing
- 2011-08-23 IN IN2188CHN2014 patent/IN2014CN02188A/en unknown
- 2011-08-23 EA EA201490175A patent/EA029305B1/ru unknown
- 2011-08-23 MY MYPI2014000197A patent/MY184277A/en unknown
- 2011-08-23 CN CN201180072842.2A patent/CN103826608A/zh active Pending
- 2011-08-23 SG SG2014013205A patent/SG2014013205A/en unknown
- 2011-08-23 KR KR1020147006855A patent/KR101751585B1/ko active IP Right Review Request
- 2011-08-23 NZ NZ620040A patent/NZ620040A/en not_active IP Right Cessation
- 2011-08-23 AU AU2011375432A patent/AU2011375432B2/en active Active
- 2011-08-23 BR BR112014000547-8A patent/BR112014000547B1/pt active IP Right Grant
- 2011-08-23 KR KR1020187032491A patent/KR102034606B1/ko active IP Right Grant
- 2011-08-23 JP JP2014527128A patent/JP5919597B2/ja active Active
- 2011-08-23 KR KR1020177016779A patent/KR101919269B1/ko active IP Right Grant
- 2011-08-23 CN CN201810400642.9A patent/CN108619089A/zh active Pending
- 2011-08-23 KR KR1020207002722A patent/KR20200013103A/ko not_active Application Discontinuation
-
2014
- 2014-01-20 IL IL230547A patent/IL230547A/en active IP Right Grant
- 2014-01-30 CR CR20140053A patent/CR20140053A/es unknown
- 2014-02-10 ZA ZA2014/01027A patent/ZA201401027B/en unknown
-
2016
- 2016-04-27 AU AU2016202661A patent/AU2016202661B2/en active Active
- 2016-06-16 PH PH12016501175A patent/PH12016501175B1/en unknown
-
2018
- 2018-04-23 AU AU2018202807A patent/AU2018202807B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20210252021A1 (en) | Formulations of deoxycholic acid and salts thereof | |
| AU2018202807B2 (en) | Formulations of deoxycholic acid and salts thereof | |
| US11179404B2 (en) | Formulations of deoxycholic acid and salts thereof | |
| EP3305298B1 (en) | Formulations of deoxycholic acid and salts thereof | |
| JP6219430B2 (ja) | デオキシコール酸およびその塩類の製剤 | |
| JP6594486B2 (ja) | デオキシコール酸およびその塩類の製剤 | |
| JP6356329B2 (ja) | デオキシコール酸およびその塩類の製剤 | |
| EA034320B1 (ru) | Композиции дезоксихолата натрия |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20140409 |