KR101879197B1 - 전분 과립의 제조 방법 및 구강 내 붕괴정 - Google Patents

전분 과립의 제조 방법 및 구강 내 붕괴정 Download PDF

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KR101879197B1
KR101879197B1 KR1020147032530A KR20147032530A KR101879197B1 KR 101879197 B1 KR101879197 B1 KR 101879197B1 KR 1020147032530 A KR1020147032530 A KR 1020147032530A KR 20147032530 A KR20147032530 A KR 20147032530A KR 101879197 B1 KR101879197 B1 KR 101879197B1
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South Korea
Prior art keywords
starch
fluidized bed
starch granules
granules
hardness
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KR1020147032530A
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English (en)
Korean (ko)
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KR20150013562A (ko
Inventor
마사오 우메자키
히로시게 무라세
토시오 우노
토시유키 니와
Original Assignee
니혼 콘 스타치 가부시키가이샤
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
    • C08B30/06—Drying; Forming
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
    • C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
    • C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
    • C08B30/14—Cold water dispersible or pregelatinised starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L3/00—Compositions of starch, amylose or amylopectin or of their derivatives or degradation products
    • C08L3/02—Starch; Degradation products thereof, e.g. dextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2303/00—Characterised by the use of starch, amylose or amylopectin or of their derivatives or degradation products
    • C08J2303/02—Starch; Degradation products thereof, e.g. dextrin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
KR1020147032530A 2012-04-27 2013-04-23 전분 과립의 제조 방법 및 구강 내 붕괴정 Expired - Fee Related KR101879197B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2012-103267 2012-04-27
JP2012103267 2012-04-27
PCT/JP2013/061900 WO2013161805A1 (ja) 2012-04-27 2013-04-23 澱粉顆粒の製造方法および口腔内崩壊錠

Publications (2)

Publication Number Publication Date
KR20150013562A KR20150013562A (ko) 2015-02-05
KR101879197B1 true KR101879197B1 (ko) 2018-08-17

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KR1020147032530A Expired - Fee Related KR101879197B1 (ko) 2012-04-27 2013-04-23 전분 과립의 제조 방법 및 구강 내 붕괴정

Country Status (8)

Country Link
US (1) US9642807B2 (https=)
EP (1) EP2842986B1 (https=)
JP (1) JP5879668B2 (https=)
KR (1) KR101879197B1 (https=)
IL (1) IL235293A (https=)
IN (1) IN2014DN09313A (https=)
MY (1) MY169160A (https=)
WO (1) WO2013161805A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6632960B2 (ja) * 2016-12-07 2020-01-22 オルガノフードテック株式会社 澱粉の製造方法
JP7133970B2 (ja) * 2018-04-27 2022-09-09 株式会社エクセディ 回転電機
JP7782842B2 (ja) * 2022-06-02 2025-12-09 株式会社パウレック 速崩壊性圧縮成形物の製造方法および速崩壊性圧縮成形物
CN115532168B (zh) * 2022-10-18 2024-06-25 江苏福瑞达新材料有限公司 一种用于化工材料的造粒设备及其使用方法
CN115819806A (zh) * 2022-12-27 2023-03-21 湖北三江丰源实业有限公司 一种阳离子淀粉颗粒的制备方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS535725B2 (https=) 1973-03-05 1978-03-01
JPS5399340A (en) 1977-02-08 1978-08-30 Nisshin Flour Milling Co Production of starch granules
JPS5827774B2 (ja) 1977-08-23 1983-06-11 武田薬品工業株式会社 殿粉粒子の製造法
JPS5827774A (ja) 1981-08-12 1983-02-18 Sumitomo Chem Co Ltd 土と推進管との摩擦力を減ずる推進工法
FR2647050B1 (fr) * 1989-05-16 1991-11-22 Seppic Sa Procede de fabrication d'un amidon directement compressible en vue de l'utilisation dans la fabrication de comprimes et comprimes obtenus
US6221420B1 (en) 1993-07-30 2001-04-24 National Starch And Chemical Investment Holding Corporation Foods containing thermally-inhibited starches and flours
US5720822A (en) 1995-06-07 1998-02-24 National Starch And Chemical Investment Holding Corporation Thermally-inhibited pregelatinized non-granular starches and flours and process for their production
US6451121B2 (en) 1993-07-30 2002-09-17 National Starch And Chemical Investment Holding Corporation Thermally-inhibited non-pregelatinized granular starches and flours and process for their preparation
US5725676A (en) 1993-07-30 1998-03-10 National Starch And Chemical Investment Holding Corporation Thermally inhibited starches and flours and process for their production
US5932017A (en) 1993-07-30 1999-08-03 National Starch And Chemical Investment Holding Corporation Thermally-inhibited non-pregelatinized granular starches and flours and process for their preparation
DE69426211T2 (de) 1994-06-29 2001-05-17 Meiji Seika Kaisha Ltd., Tokio/Tokyo Colistinsulfat enthaltende stabilisierte zusammensetzung
ES2211393T5 (es) * 1994-07-29 2009-04-16 National Starch And Chemical Investment Holding Corporation Almidones y harinas termicamente inhibidos, y procedimiento para su fabricacion.
US5718770A (en) 1994-08-25 1998-02-17 National Starch And Chemical Investment Holding Corporation Thermally-inhibited pregelatinized granular starches and flours and process for their production
JP4841564B2 (ja) * 2005-12-06 2011-12-21 旭化成ケミカルズ株式会社 高速直接打錠による錠剤の製造方法
JP2008032767A (ja) 2006-07-26 2008-02-14 Matsushita Electric Ind Co Ltd 能動騒音低減システム
CA2663451A1 (en) * 2006-09-14 2008-03-20 Astellas Pharma Inc. Rapidly disintegrating tablets in buccal cavity and manufacturing method thereof
WO2009013346A1 (en) 2007-07-26 2009-01-29 Cargill, Incorporated Process for modifying starches
US20100330369A1 (en) 2008-02-22 2010-12-30 Cargill Incorporated Pregelatinized starches as carrier materials for liquid components
US8431618B2 (en) 2008-03-31 2013-04-30 Asahi Kasei Chemicals Corporation Processed starch powder with excellent disintegration properties and manufacturing method thereof
JP2012509329A (ja) * 2008-11-19 2012-04-19 アバントール パフォーマンス マテリアルズ， インコーポレイテッド 直接圧縮可能で高機能性な顆粒状の微結晶性セルロースベース賦形剤、それらの製造プロセスおよび使用
BR112012025473B1 (pt) 2010-04-07 2020-05-05 Cargill, Incorporated amido pregelatinizado, processo de preparação e uso do mesmo, alimento para bebês, fórmula infantil e bico de dois fluidos para uso em um amido seco por pulverização

Also Published As

Publication number Publication date
US20150141525A1 (en) 2015-05-21
JPWO2013161805A1 (ja) 2015-12-24
EP2842986B1 (en) 2018-12-26
WO2013161805A1 (ja) 2013-10-31
IN2014DN09313A (https=) 2015-07-10
JP5879668B2 (ja) 2016-03-08
US9642807B2 (en) 2017-05-09
KR20150013562A (ko) 2015-02-05
EP2842986A1 (en) 2015-03-04
IL235293A (en) 2017-02-28
MY169160A (en) 2019-02-19
EP2842986A4 (en) 2015-09-09

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