KR101713581B1 - Hig2 및 urlc10 에피토프 펩티드 및 이를 포함하는 백신 - Google Patents

Hig2 및 urlc10 에피토프 펩티드 및 이를 포함하는 백신 Download PDF

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KR101713581B1
KR101713581B1 KR1020117005809A KR20117005809A KR101713581B1 KR 101713581 B1 KR101713581 B1 KR 101713581B1 KR 1020117005809 A KR1020117005809 A KR 1020117005809A KR 20117005809 A KR20117005809 A KR 20117005809A KR 101713581 B1 KR101713581 B1 KR 101713581B1
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hla
peptide
cancer
antigen
peptides
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KR20110045052A (ko
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타쿠야 츠노다
류지 오사와
사치코 요시무라
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온코세라피 사이언스 가부시키가이샤
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020117005809A 2008-08-19 2009-08-14 Hig2 및 urlc10 에피토프 펩티드 및 이를 포함하는 백신 Active KR101713581B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8997208P 2008-08-19 2008-08-19
US61/089,972 2008-08-19
PCT/JP2009/003897 WO2010021112A1 (en) 2008-08-19 2009-08-14 Hig2 and urlc10 epitope peptide and vaccines containing the same

Publications (2)

Publication Number Publication Date
KR20110045052A KR20110045052A (ko) 2011-05-03
KR101713581B1 true KR101713581B1 (ko) 2017-03-08

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ID=41707003

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KR1020117005809A Active KR101713581B1 (ko) 2008-08-19 2009-08-14 Hig2 및 urlc10 에피토프 펩티드 및 이를 포함하는 백신

Country Status (16)

Country Link
US (1) US9119800B2 (https=)
EP (1) EP2328600B9 (https=)
JP (1) JP5633025B2 (https=)
KR (1) KR101713581B1 (https=)
CN (2) CN102186491B (https=)
AU (1) AU2009283763B2 (https=)
BR (1) BRPI0917391A2 (https=)
CA (1) CA2734467C (https=)
DK (1) DK2328600T3 (https=)
ES (1) ES2566011T3 (https=)
IL (1) IL211117A (https=)
MX (2) MX337756B (https=)
RU (1) RU2529373C2 (https=)
SG (2) SG193806A1 (https=)
TW (2) TWI580431B (https=)
WO (1) WO2010021112A1 (https=)

Families Citing this family (11)

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Publication number Priority date Publication date Assignee Title
TWI596109B (zh) * 2007-02-21 2017-08-21 腫瘤療法 科學股份有限公司 表現腫瘤相關抗原之癌症的胜肽疫苗
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
SMT201800444T1 (it) * 2010-11-17 2018-09-13 Aduro Biotech Inc Metodi e composizioni per indurre una risposta immunitaria contro egfrviii
WO2014010232A1 (en) 2012-07-10 2014-01-16 Oncotherapy Science, Inc. Ly6k epitope peptides for th1 cells and vaccines containing the same
SG11201700838VA (en) 2014-08-04 2017-03-30 Oncotherapy Science Inc Urlc10-derived peptide and vaccine containing same
AU2016306408B2 (en) 2015-08-10 2021-02-11 Toray Industries, Inc. Immune inducer
CA2994929A1 (en) 2015-08-12 2017-02-16 Oncotherapy Science, Inc. Depdc1-derived peptide and vaccine containing same
JP7538601B2 (ja) 2017-04-26 2024-08-22 ユーリカ セラピューティックス, インコーポレイテッド キメラ活性化受容体及びキメラ刺激受容体を発現する細胞並びにその使用
BR112019027133B8 (pt) 2017-06-20 2022-08-09 Inst Curie Uso de uma célula imune modificada deficiente para suv39h1
CN115300609A (zh) * 2021-05-08 2022-11-08 西湖大学 缺氧诱导脂滴相关蛋白(hilpda)在预防或治疗高血脂相关疾病中的应用
CN120842356A (zh) * 2025-07-25 2025-10-28 广西医科大学附属肿瘤医院 Ly6k抗原表位肽、组合物及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001011044A1 (fr) 1999-08-05 2001-02-15 Kyogo Itoh Antigene de tumeur
WO2005019475A2 (en) 2003-08-20 2005-03-03 Oncotherapy Science, Inc. Hypoxia-inducible protein 2 (hig2), a novel therapeutic potential target of renal cell carcinoma (rcc)
WO2006090810A2 (en) * 2005-02-25 2006-08-31 Oncotherapy Science, Inc. Peptide vaccines for lung cancers expressing ttk, urlc10 or koc1 polypeptides
WO2007029778A1 (ja) 2005-09-07 2007-03-15 Nec Corporation Hla結合性ペプチド、それをコードするdna断片および組み換えベクター

Family Cites Families (18)

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US20070014787A1 (en) 1998-07-15 2007-01-18 Human Genome Sciences, Inc. 71 human secreted proteins
WO2001023426A2 (en) 1999-09-30 2001-04-05 Varian Associates, Inc. Hypoxia-related human genes, proteins, and uses thereof
EP1474528A4 (en) 2000-10-13 2006-06-14 Protein Design Labs Inc METHODS OF DIAGNOSIS OF PROSTATE CANCER, COMPOSITIONS AND METHODS OF EXAMINING PROSTATE CANCER MODULATORS
US20030232350A1 (en) 2001-11-13 2003-12-18 Eos Biotechnology, Inc. Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
US20070015271A1 (en) 2002-04-04 2007-01-18 Rosen Craig A Human secreted proteins
US20060024692A1 (en) 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
TW200413725A (en) 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
WO2005019258A2 (en) 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
CA2570392A1 (en) 2004-06-21 2005-12-29 Green Peptide Co., Ltd. Peptide vaccine for cancer therapy
CN101175862A (zh) 2005-02-10 2008-05-07 肿瘤疗法科学股份有限公司 诊断膀胱癌的方法
CA2599875A1 (en) 2005-03-03 2006-09-08 Takeda Pharmaceutical Company Limited Preventive/therapeutic agent for cancer
WO2007013575A2 (en) 2005-07-28 2007-02-01 Oncotherapy Science, Inc. Method for diagnosing and treating renal cell carcinoma
JP4840858B2 (ja) 2006-03-16 2011-12-21 学校法人慶應義塾 癌ワクチン
AU2007259667B2 (en) * 2006-06-16 2012-06-14 Oncotherapy Science, Inc. SPARC-derived tumor rejection antigenic peptides and medicaments comprising the same
TWI596109B (zh) * 2007-02-21 2017-08-21 腫瘤療法 科學股份有限公司 表現腫瘤相關抗原之癌症的胜肽疫苗
WO2009016691A1 (en) 2007-07-30 2009-02-05 Oncotherapy Science, Inc. Cancer associated gene ly6k
TW201000115A (en) 2008-06-11 2010-01-01 Oncotherapy Science Inc IQGAP3 epitope peptides and vaccines containing the same
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001011044A1 (fr) 1999-08-05 2001-02-15 Kyogo Itoh Antigene de tumeur
WO2005019475A2 (en) 2003-08-20 2005-03-03 Oncotherapy Science, Inc. Hypoxia-inducible protein 2 (hig2), a novel therapeutic potential target of renal cell carcinoma (rcc)
WO2006090810A2 (en) * 2005-02-25 2006-08-31 Oncotherapy Science, Inc. Peptide vaccines for lung cancers expressing ttk, urlc10 or koc1 polypeptides
WO2007029778A1 (ja) 2005-09-07 2007-03-15 Nec Corporation Hla結合性ペプチド、それをコードするdna断片および組み換えベクター

Also Published As

Publication number Publication date
RU2529373C2 (ru) 2014-09-27
AU2009283763A1 (en) 2010-02-25
JP5633025B2 (ja) 2014-12-03
HK1157204A1 (zh) 2012-06-29
CA2734467A1 (en) 2010-02-25
CA2734467C (en) 2017-10-03
MX337756B (es) 2016-03-17
JP2012500184A (ja) 2012-01-05
IL211117A0 (en) 2011-04-28
AU2009283763A2 (en) 2011-07-07
CN104958753B (zh) 2018-09-25
EP2328600A4 (en) 2013-03-06
SG10201610206VA (en) 2017-01-27
US20110243973A1 (en) 2011-10-06
MX355054B (es) 2018-04-03
EP2328600B9 (en) 2016-07-13
BRPI0917391A2 (pt) 2015-12-01
CN102186491B (zh) 2015-06-10
US9119800B2 (en) 2015-09-01
TWI580431B (zh) 2017-05-01
TW201019952A (en) 2010-06-01
IL211117A (en) 2017-03-30
DK2328600T3 (en) 2016-03-29
KR20110045052A (ko) 2011-05-03
WO2010021112A1 (en) 2010-02-25
EP2328600A1 (en) 2011-06-08
MX2011001883A (es) 2011-03-29
TWI543767B (zh) 2016-08-01
CN104958753A (zh) 2015-10-07
SG193806A1 (en) 2013-10-30
ES2566011T3 (es) 2016-04-08
EP2328600B1 (en) 2016-01-27
CN102186491A (zh) 2011-09-14
RU2011110376A (ru) 2012-09-27
TW201500055A (zh) 2015-01-01
AU2009283763B2 (en) 2014-06-19

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