KR101690590B1 - 친화력-성숙 CRIg 변이체 - Google Patents

친화력-성숙 CRIg 변이체 Download PDF

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KR101690590B1
KR101690590B1 KR1020107027276A KR20107027276A KR101690590B1 KR 101690590 B1 KR101690590 B1 KR 101690590B1 KR 1020107027276 A KR1020107027276 A KR 1020107027276A KR 20107027276 A KR20107027276 A KR 20107027276A KR 101690590 B1 KR101690590 B1 KR 101690590B1
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crig
thr
leu
ser
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KR20110020798A (ko
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사크데브 에스. 시드후
빙 리
멘노 반 루케렌 캄파그네
크리스티안 위스만
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제넨테크, 인크.
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
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    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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    • AHUMAN NECESSITIES
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Diabetes (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
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  • Biochemistry (AREA)
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  • Virology (AREA)
  • Neurology (AREA)
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  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
KR1020107027276A 2008-05-06 2009-05-06 친화력-성숙 CRIg 변이체 Expired - Fee Related KR101690590B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5088808P 2008-05-06 2008-05-06
US61/050,888 2008-05-06
US18965308P 2008-08-20 2008-08-20
US61/189,653 2008-08-20
PCT/US2009/043020 WO2009137605A2 (en) 2008-05-06 2009-05-06 AFFINITY MATURED CRIg VARIANTS

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020167035910A Division KR20170001711A (ko) 2008-05-06 2009-05-06 친화력-성숙 CRIg 변이체

Publications (2)

Publication Number Publication Date
KR20110020798A KR20110020798A (ko) 2011-03-03
KR101690590B1 true KR101690590B1 (ko) 2016-12-28

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ID=41168511

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KR1020107027276A Expired - Fee Related KR101690590B1 (ko) 2008-05-06 2009-05-06 친화력-성숙 CRIg 변이체
KR1020167035910A Ceased KR20170001711A (ko) 2008-05-06 2009-05-06 친화력-성숙 CRIg 변이체

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020167035910A Ceased KR20170001711A (ko) 2008-05-06 2009-05-06 친화력-성숙 CRIg 변이체

Country Status (28)

Country Link
US (2) US9234024B2 (https=)
EP (2) EP2280996B1 (https=)
JP (2) JP5836800B2 (https=)
KR (2) KR101690590B1 (https=)
CN (2) CN104558151A (https=)
AR (1) AR071635A1 (https=)
AU (1) AU2009244300B2 (https=)
BR (1) BRPI0912003A2 (https=)
CA (1) CA2720685C (https=)
CL (1) CL2009001083A1 (https=)
CY (1) CY1118240T1 (https=)
DK (1) DK2280996T3 (https=)
ES (1) ES2605471T3 (https=)
HK (1) HK1210184A1 (https=)
HR (1) HRP20161580T1 (https=)
HU (1) HUE030092T2 (https=)
IL (2) IL208379A (https=)
LT (1) LT2280996T (https=)
MX (1) MX2010011372A (https=)
PE (2) PE20091923A1 (https=)
PL (1) PL2280996T3 (https=)
PT (1) PT2280996T (https=)
RU (2) RU2015117054A (https=)
SG (1) SG190596A1 (https=)
SI (1) SI2280996T1 (https=)
TW (1) TWI508973B (https=)
WO (1) WO2009137605A2 (https=)
ZA (1) ZA201006937B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104231085B (zh) * 2013-09-05 2017-03-15 复旦大学附属肿瘤医院 靶向特异性补体系统抑制剂、其制备方法及应用
US11535655B2 (en) * 2019-12-06 2022-12-27 Cheer Global Limited Method of treating inflammatory bowel disease
CN113583107B (zh) * 2021-07-28 2023-11-10 复旦大学 CRIg功能区蛋白变体及其应用
WO2023080788A1 (en) * 2021-11-05 2023-05-11 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Tryptophan depletion induces production and presentation of tryptophan to phenylalanine substitutions
EP4590697A2 (en) * 2022-09-20 2025-07-30 Visterra, Inc. Treatment of complement mediated diseases and disorders with c3b-antibodies
TW202523706A (zh) * 2023-11-13 2025-06-16 大陸商瀋陽三生製藥有限責任公司 一種靶向C3b的雙功能融合蛋白及其製備方法與用途
CN118584103B (zh) * 2024-07-05 2025-06-17 中国医科大学附属第一医院 中枢神经精神狼疮脑脊液诊断标志物及其应用

Citations (1)

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