CN104558151A - 亲和力成熟的CRIg变体 - Google Patents

亲和力成熟的CRIg变体 Download PDF

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Publication number
CN104558151A
CN104558151A CN201410686051.4A CN201410686051A CN104558151A CN 104558151 A CN104558151 A CN 104558151A CN 201410686051 A CN201410686051 A CN 201410686051A CN 104558151 A CN104558151 A CN 104558151A
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CN
China
Prior art keywords
crig
variant
complement
amino acid
binding
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Pending
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CN201410686051.4A
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English (en)
Chinese (zh)
Inventor
萨科德夫·S·西多
李冰
曼诺·范卢克伦坎帕格尼
克里斯琴·威斯曼
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Genentech Inc
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Genentech Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41168511&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN104558151(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CN104558151A publication Critical patent/CN104558151A/zh
Pending legal-status Critical Current

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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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CN201410686051.4A 2008-05-06 2009-05-06 亲和力成熟的CRIg变体 Pending CN104558151A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US5088808P 2008-05-06 2008-05-06
US61/050,888 2008-05-06
US18965308P 2008-08-20 2008-08-20
US61/189,653 2008-08-20

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN200980116490.9A Division CN102015763B (zh) 2008-05-06 2009-05-06 亲和力成熟的CRIg变体

Publications (1)

Publication Number Publication Date
CN104558151A true CN104558151A (zh) 2015-04-29

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ID=41168511

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201410686051.4A Pending CN104558151A (zh) 2008-05-06 2009-05-06 亲和力成熟的CRIg变体
CN200980116490.9A Expired - Fee Related CN102015763B (zh) 2008-05-06 2009-05-06 亲和力成熟的CRIg变体

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CN200980116490.9A Expired - Fee Related CN102015763B (zh) 2008-05-06 2009-05-06 亲和力成熟的CRIg变体

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Country Link
US (2) US9234024B2 (https=)
EP (2) EP2280996B1 (https=)
JP (2) JP5836800B2 (https=)
KR (2) KR101690590B1 (https=)
CN (2) CN104558151A (https=)
AR (1) AR071635A1 (https=)
AU (1) AU2009244300B2 (https=)
BR (1) BRPI0912003A2 (https=)
CA (1) CA2720685C (https=)
CL (1) CL2009001083A1 (https=)
CY (1) CY1118240T1 (https=)
DK (1) DK2280996T3 (https=)
ES (1) ES2605471T3 (https=)
HK (1) HK1210184A1 (https=)
HR (1) HRP20161580T1 (https=)
HU (1) HUE030092T2 (https=)
IL (2) IL208379A (https=)
LT (1) LT2280996T (https=)
MX (1) MX2010011372A (https=)
PE (2) PE20091923A1 (https=)
PL (1) PL2280996T3 (https=)
PT (1) PT2280996T (https=)
RU (2) RU2015117054A (https=)
SG (1) SG190596A1 (https=)
SI (1) SI2280996T1 (https=)
TW (1) TWI508973B (https=)
WO (1) WO2009137605A2 (https=)
ZA (1) ZA201006937B (https=)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN113583107A (zh) * 2021-07-28 2021-11-02 复旦大学 CRIg功能区蛋白变体及其应用

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CN104231085B (zh) * 2013-09-05 2017-03-15 复旦大学附属肿瘤医院 靶向特异性补体系统抑制剂、其制备方法及应用
US11535655B2 (en) * 2019-12-06 2022-12-27 Cheer Global Limited Method of treating inflammatory bowel disease
WO2023080788A1 (en) * 2021-11-05 2023-05-11 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Tryptophan depletion induces production and presentation of tryptophan to phenylalanine substitutions
EP4590697A2 (en) * 2022-09-20 2025-07-30 Visterra, Inc. Treatment of complement mediated diseases and disorders with c3b-antibodies
TW202523706A (zh) * 2023-11-13 2025-06-16 大陸商瀋陽三生製藥有限責任公司 一種靶向C3b的雙功能融合蛋白及其製備方法與用途
CN118584103B (zh) * 2024-07-05 2025-06-17 中国医科大学附属第一医院 中枢神经精神狼疮脑脊液诊断标志物及其应用

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