JP5836800B2 - 親和性成熟ＣＲＩｇ変異体 - Google Patents

親和性成熟ＣＲＩｇ変異体 Download PDF

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JP5836800B2
JP5836800B2 JP2011508636A JP2011508636A JP5836800B2 JP 5836800 B2 JP5836800 B2 JP 5836800B2 JP 2011508636 A JP2011508636 A JP 2011508636A JP 2011508636 A JP2011508636 A JP 2011508636A JP 5836800 B2 JP5836800 B2 JP 5836800B2
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crig
complement
variant
seq
disease
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JP2011519950A (ja
JP2011519950A5 (https=
Inventor
サチデヴ， エス． シドゥ，
サチデヴ， エス． シドゥ，
ビン リ，
ビン リ，
ルッケレン カンパーニュ， メンノ ヴァン
ルッケレン カンパーニュ， メンノ ヴァン
クリスチャン ウィースマン，
クリスチャン ウィースマン，
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Genentech Inc
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Genentech Inc
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    • C07—ORGANIC CHEMISTRY
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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JP2011508636A 2008-05-06 2009-05-06 親和性成熟ＣＲＩｇ変異体 Expired - Fee Related JP5836800B2 (ja)

Applications Claiming Priority (5)

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US5088808P 2008-05-06 2008-05-06
US61/050,888 2008-05-06
US18965308P 2008-08-20 2008-08-20
US61/189,653 2008-08-20
PCT/US2009/043020 WO2009137605A2 (en) 2008-05-06 2009-05-06 AFFINITY MATURED CRIg VARIANTS

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JP2011519950A JP2011519950A (ja) 2011-07-14
JP2011519950A5 JP2011519950A5 (https=) 2013-03-07
JP5836800B2 true JP5836800B2 (ja) 2015-12-24

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JP2015023559A Pending JP2015145369A (ja) 2008-05-06 2015-02-09 親和性成熟ＣＲＩｇ変異体

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US (2) US9234024B2 (https=)
EP (2) EP2280996B1 (https=)
JP (2) JP5836800B2 (https=)
KR (2) KR20170001711A (https=)
CN (2) CN102015763B (https=)
AR (1) AR071635A1 (https=)
AU (1) AU2009244300B2 (https=)
BR (1) BRPI0912003A2 (https=)
CA (1) CA2720685C (https=)
CL (1) CL2009001083A1 (https=)
CY (1) CY1118240T1 (https=)
DK (1) DK2280996T3 (https=)
ES (1) ES2605471T3 (https=)
HK (1) HK1210184A1 (https=)
HR (1) HRP20161580T1 (https=)
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PE (2) PE20141549A1 (https=)
PL (1) PL2280996T3 (https=)
PT (1) PT2280996T (https=)
RU (2) RU2553517C2 (https=)
SG (1) SG190596A1 (https=)
SI (1) SI2280996T1 (https=)
TW (1) TWI508973B (https=)
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CA3159053A1 (en) * 2019-12-06 2021-06-10 Sui Yi Kwok Method of treating inflammatory bowel disease
CN113583107B (zh) * 2021-07-28 2023-11-10 复旦大学 CRIg功能区蛋白变体及其应用
WO2023080788A1 (en) * 2021-11-05 2023-05-11 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Tryptophan depletion induces production and presentation of tryptophan to phenylalanine substitutions
AU2023347940A1 (en) * 2022-09-20 2025-03-27 Visterra, Inc. Treatment of complement mediated diseases and disorders with c3b-antibodies
WO2025103318A1 (zh) * 2023-11-13 2025-05-22 沈阳三生制药有限责任公司 一种靶向C3b的双功能融合蛋白及其制备方法与用途
CN118584103B (zh) * 2024-07-05 2025-06-17 中国医科大学附属第一医院 中枢神经精神狼疮脑脊液诊断标志物及其应用

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