KR101651678B1 - 루푸스를 확인 및 치료하기 위한 방법 및 조성물 - Google Patents

루푸스를 확인 및 치료하기 위한 방법 및 조성물 Download PDF

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KR101651678B1
KR101651678B1 KR1020097026436A KR20097026436A KR101651678B1 KR 101651678 B1 KR101651678 B1 KR 101651678B1 KR 1020097026436 A KR1020097026436 A KR 1020097026436A KR 20097026436 A KR20097026436 A KR 20097026436A KR 101651678 B1 KR101651678 B1 KR 101651678B1
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snps
lupus
gene
snp
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KR20100021612A (ko
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티모시 더블유. 버렌스
제프리 홈
워드 에이. 오트만
로버트 로얄 그라함
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제넨테크, 인크.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
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    • G06—COMPUTING OR CALCULATING; COUNTING
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    • C12Q2533/00—Reactions characterised by the enzymatic reaction principle used
    • C12Q2533/10—Reactions characterised by the enzymatic reaction principle used the purpose being to increase the length of an oligonucleotide strand
    • C12Q2533/101—Primer extension
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]

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  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Physics & Mathematics (AREA)
  • General Business, Economics & Management (AREA)
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  • Theoretical Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Transplantation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020097026436A 2007-05-21 2008-05-21 루푸스를 확인 및 치료하기 위한 방법 및 조성물 Active KR101651678B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93915607P 2007-05-21 2007-05-21
US60/939,156 2007-05-21
US1328307P 2007-12-12 2007-12-12
US61/013,283 2007-12-12

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KR1020157032728A Division KR101729431B1 (ko) 2007-05-21 2008-05-21 루푸스를 확인 및 치료하기 위한 방법 및 조성물

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KR20100021612A KR20100021612A (ko) 2010-02-25
KR101651678B1 true KR101651678B1 (ko) 2016-08-26

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KR1020157032728A Active KR101729431B1 (ko) 2007-05-21 2008-05-21 루푸스를 확인 및 치료하기 위한 방법 및 조성물
KR1020097026436A Active KR101651678B1 (ko) 2007-05-21 2008-05-21 루푸스를 확인 및 치료하기 위한 방법 및 조성물
KR1020197003511A Withdrawn KR20190015629A (ko) 2007-05-21 2008-05-21 루푸스를 확인 및 치료하기 위한 방법 및 조성물
KR1020177009940A Active KR101947093B1 (ko) 2007-05-21 2008-05-21 루푸스를 확인 및 치료하기 위한 방법 및 조성물

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KR1020177009940A Active KR101947093B1 (ko) 2007-05-21 2008-05-21 루푸스를 확인 및 치료하기 위한 방법 및 조성물

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US (1) US20110046094A1 (enExample)
EP (3) EP2612924B1 (enExample)
JP (4) JP5728226B2 (enExample)
KR (4) KR101729431B1 (enExample)
CN (3) CN104593488B (enExample)
AU (1) AU2008254582A1 (enExample)
BR (1) BRPI0811930B8 (enExample)
CA (1) CA2690608C (enExample)
ES (1) ES2661249T3 (enExample)
HK (1) HK1255086A1 (enExample)
IL (1) IL201949A0 (enExample)
MX (3) MX378733B (enExample)
RU (1) RU2009147281A (enExample)
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KR20240021336A (ko) 2022-08-09 2024-02-19 심재홍 수액 채취장치의 냉각기 구조

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AU2009296393A1 (en) * 2008-09-26 2010-04-01 Genentech, Inc. Methods for treating, diagnosing, and monitoring lupus
US20100105061A1 (en) * 2008-10-29 2010-04-29 University Of Southern California Autoimmune genes identified in systemic lupus erythematosus (sle)
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US20130317006A1 (en) 2012-05-24 2013-11-28 Amy Yasko Use of polymorphisms for identifying individuals at risk of developing autism
WO2015081052A1 (en) 2013-11-27 2015-06-04 Yasko Amy Use of polymorphisms for identifying individuals at risk of developing autism
EP3822367A1 (en) * 2015-06-24 2021-05-19 Oxford BioDynamics PLC Detection processes using sites of chromosome interaction
CN110459312B (zh) * 2018-05-07 2024-01-12 深圳华大生命科学研究院 类风湿性关节炎易感位点及其应用
WO2021127589A1 (en) * 2019-12-18 2021-06-24 The Children's Hospital Of Philadelphia Novel druggable targets for the treatment of inflammatory diseases such as systemic lupus erythematosus (sle) and methods for diagnosis and treatment using the same
CN116030889A (zh) * 2023-02-16 2023-04-28 复旦大学 一种线粒体异质性分布中分配差异率计算的模型化方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240021336A (ko) 2022-08-09 2024-02-19 심재홍 수액 채취장치의 냉각기 구조

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WO2008144761A2 (en) 2008-11-27
CN104593488B (zh) 2018-06-12
KR20100021612A (ko) 2010-02-25
KR101729431B1 (ko) 2017-04-21
CN103298950A (zh) 2013-09-11
WO2008144761A3 (en) 2009-07-02
JP2010528590A (ja) 2010-08-26
US20110046094A1 (en) 2011-02-24
HK1189246A1 (en) 2014-05-30
HK1255086A1 (en) 2019-08-02
MX353428B (es) 2018-01-12
EP3318643A2 (en) 2018-05-09
ES2661249T3 (es) 2018-03-28
BRPI0811930B8 (pt) 2021-05-25
EP2158335A2 (en) 2010-03-03
CN103298950B (zh) 2015-01-21
JP2018126146A (ja) 2018-08-16
CN108753946A (zh) 2018-11-06
JP6080059B2 (ja) 2017-02-15
RU2009147281A (ru) 2011-06-27
CN104593488A (zh) 2015-05-06
BRPI0811930B1 (pt) 2019-11-05
MX378733B (es) 2025-03-10
CA2690608A1 (en) 2008-11-27
IL201949A0 (en) 2010-06-16
MX2009012531A (es) 2009-12-03
EP2612924A3 (en) 2013-10-23
JP2017035088A (ja) 2017-02-16
KR101947093B1 (ko) 2019-02-12
EP3318643A3 (en) 2018-06-20
JP2015164426A (ja) 2015-09-17
KR20170042831A (ko) 2017-04-19
HK1209459A1 (en) 2016-04-01
EP2612924A2 (en) 2013-07-10
EP2612924B1 (en) 2017-12-20
AU2008254582A1 (en) 2008-11-27
KR20190015629A (ko) 2019-02-13
MX343167B (es) 2016-10-26
JP5728226B2 (ja) 2015-06-03
CA2690608C (en) 2020-07-21
KR20150133861A (ko) 2015-11-30
BRPI0811930A2 (pt) 2014-11-25

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