MX353428B - Métodos y composiciones para identificar y tratar lupus. - Google Patents
Métodos y composiciones para identificar y tratar lupus.Info
- Publication number
- MX353428B MX353428B MX2016010728A MX2016010728A MX353428B MX 353428 B MX353428 B MX 353428B MX 2016010728 A MX2016010728 A MX 2016010728A MX 2016010728 A MX2016010728 A MX 2016010728A MX 353428 B MX353428 B MX 353428B
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- identifying
- compositions
- treating lupus
- lupus
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
- G06Q99/00—Subject matter not provided for in other groups of this subclass
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2533/00—Reactions characterised by the enzymatic reaction principle used
- C12Q2533/10—Reactions characterised by the enzymatic reaction principle used the purpose being to increase the length of an oligonucleotide strand
- C12Q2533/101—Primer extension
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Business, Economics & Management (AREA)
- Business, Economics & Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Theoretical Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Transplantation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a un método para ayudar en la detección de la presencia de lupus en un sujeto o valorar si un sujeto se encuentra en riesgo de desarrollar lupus, el método comprendiendo detectar en una muestra biológica de dicho sujeto la presencia de una firma genética indicativa de riesgo de lupus o de desarrollar lupus, en donde dicha firma genética comprende uno o más polimorfismos de nucleótido sencillos (SNPs), y en donde al menos uno de los SNPs es rs7574865 que está ubicado en la posición 11 en una secuencia de nucleótidos mostrada en SEQ ID NO: 1.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93915607P | 2007-05-21 | 2007-05-21 | |
US1328307P | 2007-12-12 | 2007-12-12 | |
PCT/US2008/064430 WO2008144761A2 (en) | 2007-05-21 | 2008-05-21 | Methods and compositions for identifying and treating lupus |
Publications (1)
Publication Number | Publication Date |
---|---|
MX353428B true MX353428B (es) | 2018-01-12 |
Family
ID=40122294
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009012531A MX343167B (es) | 2007-05-21 | 2008-05-21 | Metodos y composiciones para identificar y tratar lupus. |
MX2016010728A MX353428B (es) | 2007-05-21 | 2008-05-21 | Métodos y composiciones para identificar y tratar lupus. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009012531A MX343167B (es) | 2007-05-21 | 2008-05-21 | Metodos y composiciones para identificar y tratar lupus. |
Country Status (14)
Country | Link |
---|---|
US (1) | US20110046094A1 (es) |
EP (3) | EP2612924B1 (es) |
JP (4) | JP5728226B2 (es) |
KR (4) | KR101651678B1 (es) |
CN (3) | CN103298950B (es) |
AU (1) | AU2008254582A1 (es) |
BR (1) | BRPI0811930B8 (es) |
CA (1) | CA2690608C (es) |
ES (1) | ES2661249T3 (es) |
HK (3) | HK1189246A1 (es) |
IL (1) | IL201949A0 (es) |
MX (2) | MX343167B (es) |
RU (1) | RU2009147281A (es) |
WO (1) | WO2008144761A2 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008144761A2 (en) * | 2007-05-21 | 2008-11-27 | Genentech, Inc. | Methods and compositions for identifying and treating lupus |
AU2009296393A1 (en) * | 2008-09-26 | 2010-04-01 | Genentech, Inc. | Methods for treating, diagnosing, and monitoring lupus |
US20100105061A1 (en) * | 2008-10-29 | 2010-04-29 | University Of Southern California | Autoimmune genes identified in systemic lupus erythematosus (sle) |
AU2010220397A1 (en) * | 2009-03-03 | 2011-07-28 | Merck Serono S.A. | BANK1 related SNPS and SLE and/or MS susceptibility |
CN106929568A (zh) * | 2009-10-07 | 2017-07-07 | 弗·哈夫曼-拉罗切有限公司 | 用于治疗、诊断和监控狼疮的方法 |
NZ602219A (en) * | 2010-03-01 | 2014-10-31 | Alexion Pharma Inc | Methods and compositions for treating degos’ disease |
AU2012214417A1 (en) * | 2011-02-10 | 2013-09-05 | Genqual Corporation | Methods of prognosing and administering treatment for inflammatory disorders |
US20130317006A1 (en) | 2012-05-24 | 2013-11-28 | Amy Yasko | Use of polymorphisms for identifying individuals at risk of developing autism |
WO2015081052A1 (en) | 2013-11-27 | 2015-06-04 | Yasko Amy | Use of polymorphisms for identifying individuals at risk of developing autism |
JP2018518203A (ja) * | 2015-06-24 | 2018-07-12 | オックスフォード バイオダイナミックス リミテッド | エピジェネティックな染色体相互作用 |
CN110459312B (zh) * | 2018-05-07 | 2024-01-12 | 深圳华大生命科学研究院 | 类风湿性关节炎易感位点及其应用 |
US20230054595A1 (en) * | 2019-12-18 | 2023-02-23 | The Children's Hospital Of Philadelphia | Novel druggable targets for the treatment of inflammatory diseases such as systemic lupus erythematosus (sle) and methods for diagnosis and treatment using the same |
KR20240021336A (ko) | 2022-08-09 | 2024-02-19 | 심재홍 | 수액 채취장치의 냉각기 구조 |
Family Cites Families (36)
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US4657760A (en) | 1979-03-20 | 1987-04-14 | Ortho Pharmaceutical Corporation | Methods and compositions using monoclonal antibody to human T cells |
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4683203A (en) | 1984-04-14 | 1987-07-28 | Redco N.V. | Immobilized enzymes, processes for preparing same, and use thereof |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US5206344A (en) | 1985-06-26 | 1993-04-27 | Cetus Oncology Corporation | Interleukin-2 muteins and polymer conjugation thereof |
IE61148B1 (en) | 1988-03-10 | 1994-10-05 | Ici Plc | Method of detecting nucleotide sequences |
GB8823869D0 (en) * | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
US5225212A (en) * | 1989-10-20 | 1993-07-06 | Liposome Technology, Inc. | Microreservoir liposome composition and method |
EP0463151B1 (en) | 1990-01-12 | 1996-06-12 | Cell Genesys, Inc. | Generation of xenogeneic antibodies |
US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
DE69127627T2 (de) * | 1990-08-29 | 1998-02-19 | Genpharm Int | Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper |
US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
GB9114948D0 (en) | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline intermediates |
US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
EP1978033A3 (en) | 1995-04-27 | 2008-12-24 | Amgen Fremont Inc. | Human antibodies derived from immunized xenomice |
AU2466895A (en) | 1995-04-28 | 1996-11-18 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
EP0912761A4 (en) | 1996-05-29 | 2004-06-09 | Cornell Res Foundation Inc | DETERMINATION OF DIFFERENCES IN THE NUCLEIC ACID SEQUENCE BY MEANS OF A COMBINATION OF LIGASE DETERMINATION AND POLYMERASE CHAIN REACTION |
EP1500329B1 (en) | 1996-12-03 | 2012-03-21 | Amgen Fremont Inc. | Human antibodies that specifically bind human TNF alpha |
AU2001265121A1 (en) | 2000-05-30 | 2001-12-11 | Applera Corporation | Methods for detecting target nucleic acids using coupled ligation and amplification |
US6900016B1 (en) | 2000-09-08 | 2005-05-31 | Applera Corporation | Polymorphisms in known genes associated with inflammatory autoimmune disease, methods of detection and uses thereof |
WO2002057414A2 (en) | 2000-10-20 | 2002-07-25 | Expression Diagnostics, Inc. | Leukocyte expression profiling |
US7205106B1 (en) | 2001-07-20 | 2007-04-17 | Roche Molecular Systems, Inc. | Association of polymorphisms in IL4-related genes with autoimmune disease |
JP2003061677A (ja) * | 2001-08-28 | 2003-03-04 | Olympus Optical Co Ltd | 全身性エリテマトーデスの感受性遺伝子およびその使用 |
US20030119004A1 (en) | 2001-12-05 | 2003-06-26 | Wenz H. Michael | Methods for quantitating nucleic acids using coupled ligation and amplification |
US7022476B2 (en) * | 2002-02-26 | 2006-04-04 | New York Society For Ruptured And Crippled Maintaining The Hospital For Special Surgery | Human FcγRIIB gene polymorphisms for assessing development of systemic lupus erythematosus and compositions for use thereof |
CA2477761A1 (en) * | 2002-03-01 | 2003-09-12 | Ravgen, Inc. | Methods for detection of genetic disorders |
JP2006521812A (ja) | 2003-03-18 | 2006-09-28 | アプレラ コーポレイション | 慢性関節リウマチに関連する遺伝的多型、その検出方法および使用 |
WO2005086872A2 (en) * | 2004-03-10 | 2005-09-22 | Celera, An Applera Corporation Business | Ptpn22 polymorphisms in diagnosis and therapy |
EP1863927A2 (en) | 2005-03-15 | 2007-12-12 | Ares Trading S.A. | Compositions and methods for treating and diagnosing inflammatory disorders |
PT2327792E (pt) | 2005-08-05 | 2013-11-21 | Genentech Inc | Métodos e composições para a detecção de distúrbios autoimunes |
US20070269827A1 (en) * | 2006-05-18 | 2007-11-22 | Oklahoma Medical Research Foundation | Predicting and Diagnosing Patients With Autoimmune Disease |
WO2008144761A2 (en) * | 2007-05-21 | 2008-11-27 | Genentech, Inc. | Methods and compositions for identifying and treating lupus |
AU2009296393A1 (en) * | 2008-09-26 | 2010-04-01 | Genentech, Inc. | Methods for treating, diagnosing, and monitoring lupus |
-
2008
- 2008-05-21 WO PCT/US2008/064430 patent/WO2008144761A2/en active Application Filing
- 2008-05-21 RU RU2009147281/10A patent/RU2009147281A/ru unknown
- 2008-05-21 US US12/600,248 patent/US20110046094A1/en not_active Abandoned
- 2008-05-21 EP EP12192837.8A patent/EP2612924B1/en active Active
- 2008-05-21 CN CN200880025560.5A patent/CN103298950B/zh active Active
- 2008-05-21 KR KR1020097026436A patent/KR101651678B1/ko active IP Right Grant
- 2008-05-21 EP EP17191337.9A patent/EP3318643A3/en not_active Withdrawn
- 2008-05-21 EP EP08769569A patent/EP2158335A2/en not_active Withdrawn
- 2008-05-21 ES ES12192837.8T patent/ES2661249T3/es active Active
- 2008-05-21 JP JP2010509537A patent/JP5728226B2/ja active Active
- 2008-05-21 BR BRPI0811930A patent/BRPI0811930B8/pt active IP Right Grant
- 2008-05-21 CN CN201410815214.4A patent/CN104593488B/zh active Active
- 2008-05-21 KR KR1020177009940A patent/KR101947093B1/ko active IP Right Grant
- 2008-05-21 KR KR1020157032728A patent/KR101729431B1/ko active IP Right Grant
- 2008-05-21 CN CN201810571366.2A patent/CN108753946A/zh active Pending
- 2008-05-21 KR KR1020197003511A patent/KR20190015629A/ko not_active Application Discontinuation
- 2008-05-21 MX MX2009012531A patent/MX343167B/es active IP Right Grant
- 2008-05-21 CA CA2690608A patent/CA2690608C/en active Active
- 2008-05-21 AU AU2008254582A patent/AU2008254582A1/en not_active Abandoned
- 2008-05-21 MX MX2016010728A patent/MX353428B/es unknown
-
2009
- 2009-11-05 IL IL201949A patent/IL201949A0/en unknown
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2014
- 2014-03-10 HK HK14102346.1A patent/HK1189246A1/xx unknown
- 2014-03-10 HK HK15109984.2A patent/HK1209459A1/xx unknown
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2015
- 2015-04-08 JP JP2015079282A patent/JP6080059B2/ja active Active
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2016
- 2016-09-13 JP JP2016178303A patent/JP2017035088A/ja active Pending
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2018
- 2018-03-19 JP JP2018050492A patent/JP2018126146A/ja active Pending
- 2018-11-07 HK HK18114216.9A patent/HK1255086A1/zh unknown
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