CN104593488B - 用于鉴定和治疗狼疮的方法和组合物 - Google Patents

用于鉴定和治疗狼疮的方法和组合物 Download PDF

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CN104593488B
CN104593488B CN201410815214.4A CN201410815214A CN104593488B CN 104593488 B CN104593488 B CN 104593488B CN 201410815214 A CN201410815214 A CN 201410815214A CN 104593488 B CN104593488 B CN 104593488B
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snp
snps
lupus
allele
pro
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CN104593488A (zh
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蒂莫西·W·贝伦斯
杰弗里·霍姆
沃德·A·奥特曼
罗伯特·R·格雷厄姆
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Genentech Inc
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
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    • C12Q2533/00—Reactions characterised by the enzymatic reaction principle used
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
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    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]

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  • Pharmacology & Pharmacy (AREA)
  • General Physics & Mathematics (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Plant Pathology (AREA)
  • Transplantation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201410815214.4A 2007-05-21 2008-05-21 用于鉴定和治疗狼疮的方法和组合物 Active CN104593488B (zh)

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US93915607P 2007-05-21 2007-05-21
US60/939,156 2007-05-21
US1328307P 2007-12-12 2007-12-12
US61/013,283 2007-12-12
CN200880025560.5A CN103298950B (zh) 2007-05-21 2008-05-21 用于鉴定和治疗狼疮的方法和组合物

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BR (1) BRPI0811930B8 (enExample)
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HK1209459A1 (en) 2016-04-01
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KR20100021612A (ko) 2010-02-25
EP2612924B1 (en) 2017-12-20
ES2661249T3 (es) 2018-03-28
IL201949A0 (en) 2010-06-16
CN108753946A (zh) 2018-11-06
CA2690608A1 (en) 2008-11-27
BRPI0811930B8 (pt) 2021-05-25
KR101651678B1 (ko) 2016-08-26
MX2009012531A (es) 2009-12-03
KR101947093B1 (ko) 2019-02-12
JP5728226B2 (ja) 2015-06-03
EP3318643A2 (en) 2018-05-09
EP3318643A3 (en) 2018-06-20
AU2008254582A1 (en) 2008-11-27
CA2690608C (en) 2020-07-21
RU2009147281A (ru) 2011-06-27
MX353428B (es) 2018-01-12
JP2017035088A (ja) 2017-02-16
KR20150133861A (ko) 2015-11-30
US20110046094A1 (en) 2011-02-24
KR20170042831A (ko) 2017-04-19
BRPI0811930A2 (pt) 2014-11-25
CN104593488A (zh) 2015-05-06
JP2018126146A (ja) 2018-08-16
KR101729431B1 (ko) 2017-04-21
MX378733B (es) 2025-03-10
BRPI0811930B1 (pt) 2019-11-05
CN103298950B (zh) 2015-01-21
KR20190015629A (ko) 2019-02-13
MX343167B (es) 2016-10-26
JP6080059B2 (ja) 2017-02-15
WO2008144761A2 (en) 2008-11-27
JP2010528590A (ja) 2010-08-26
WO2008144761A3 (en) 2009-07-02
EP2612924A2 (en) 2013-07-10
CN103298950A (zh) 2013-09-11
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