KR101638024B1 - 타가토스 제조용 조성물 및 과당으로부터 타가토스를 제조하는 방법 - Google Patents

타가토스 제조용 조성물 및 과당으로부터 타가토스를 제조하는 방법 Download PDF

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KR101638024B1
KR101638024B1 KR1020140143703A KR20140143703A KR101638024B1 KR 101638024 B1 KR101638024 B1 KR 101638024B1 KR 1020140143703 A KR1020140143703 A KR 1020140143703A KR 20140143703 A KR20140143703 A KR 20140143703A KR 101638024 B1 KR101638024 B1 KR 101638024B1
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KR20160047361A (ko
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이영미
김양희
양성재
박일향
김성보
조현국
박승원
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씨제이제일제당(주)
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Priority to ES15852026T priority patent/ES2721309T3/es
Priority to UAA201703549A priority patent/UA119791C2/uk
Priority to CN201580057200.3A priority patent/CN107109394B/zh
Priority to RU2017113926A priority patent/RU2701669C2/ru
Priority to PCT/KR2015/011007 priority patent/WO2016064146A1/ko
Priority to EP15852026.2A priority patent/EP3211078B1/en
Priority to JP2017521088A priority patent/JP6518761B2/ja
Priority to US15/521,243 priority patent/US10544438B2/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y501/00—Racemaces and epimerases (5.1)
    • C12Y501/03—Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/60—Sugars, e.g. mono-, di-, tri-, tetra-saccharides
    • A23V2250/634—Tagatose

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  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020140143703A 2014-10-22 2014-10-22 타가토스 제조용 조성물 및 과당으로부터 타가토스를 제조하는 방법 Active KR101638024B1 (ko)

Priority Applications (9)

Application Number Priority Date Filing Date Title
KR1020140143703A KR101638024B1 (ko) 2014-10-22 2014-10-22 타가토스 제조용 조성물 및 과당으로부터 타가토스를 제조하는 방법
UAA201703549A UA119791C2 (uk) 2014-10-22 2015-10-19 Композиція для одержання тагатози та спосіб одержання тагатози з фруктози
CN201580057200.3A CN107109394B (zh) 2014-10-22 2015-10-19 用于制备塔格糖的组合物以及从果胶制备塔格糖的方法
RU2017113926A RU2701669C2 (ru) 2014-10-22 2015-10-19 Композиция для получения тагатозы и способ получения тагатозы из фруктозы
ES15852026T ES2721309T3 (es) 2014-10-22 2015-10-19 Composición para preparar tagatosa y método para preparar tagatosa a partir de fructosa
PCT/KR2015/011007 WO2016064146A1 (ko) 2014-10-22 2015-10-19 타가토스 제조용 조성물 및 과당으로부터 타가토스를 제조하는 방법
EP15852026.2A EP3211078B1 (en) 2014-10-22 2015-10-19 Composition for preparing tagatose and method for preparing tagatose from fructose
JP2017521088A JP6518761B2 (ja) 2014-10-22 2015-10-19 タガトース製造用の組成物とフルクトースからタガトースを製造する方法
US15/521,243 US10544438B2 (en) 2014-10-22 2015-10-19 Composition for preparing tagatose and method for preparing tagatose from fructose

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020140143703A KR101638024B1 (ko) 2014-10-22 2014-10-22 타가토스 제조용 조성물 및 과당으로부터 타가토스를 제조하는 방법

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KR20160047361A KR20160047361A (ko) 2016-05-02
KR101638024B1 true KR101638024B1 (ko) 2016-07-20

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US (1) US10544438B2 (https=)
EP (1) EP3211078B1 (https=)
JP (1) JP6518761B2 (https=)
KR (1) KR101638024B1 (https=)
CN (1) CN107109394B (https=)
ES (1) ES2721309T3 (https=)
RU (1) RU2701669C2 (https=)
UA (1) UA119791C2 (https=)
WO (1) WO2016064146A1 (https=)

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KR20180013814A (ko) * 2016-07-29 2018-02-07 씨제이제일제당 (주) D-타가토스 전환 활성이 향상된 헥수론산 c4-에피머화 효소 변이체 및 이를 이용한 d-타가토스의 제조 방법
WO2020067649A1 (ko) * 2018-09-27 2020-04-02 씨제이제일제당 (주) 신규 과당-4-에피머화 효소 및 이를 이용한 타가토스의 제조 방법

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PL3322803T3 (pl) 2015-10-02 2021-09-27 Bonumose, Inc. Enzymatyczne wytwarzanie d-tagatozy
CN111344405B (zh) 2017-03-31 2023-12-22 Cj第一制糖株式会社 用于制备塔格糖的组合物和利用其制备塔格糖的方法
CA3057595C (en) * 2017-03-31 2024-11-12 Cj Cheiljedang Corporation Composition for the production of tagatose and process for the production of tagatose employing it
WO2019004702A2 (ko) * 2017-06-28 2019-01-03 주식회사 삼양사 기능성 감미료의 제조방법
EP3677675A4 (en) * 2017-08-31 2021-06-09 CJ Cheiljedang Corporation FRUCTOSE-4-EPIMERASE AND METHOD FOR MANUFACTURING TAGATOSE USING THE SAME
CN109750024B (zh) 2017-11-02 2021-12-14 中国科学院天津工业生物技术研究所 一种6磷酸塔格糖4位差向异构酶及其应用
CN108774636A (zh) * 2018-06-25 2018-11-09 嘉兴欣贝莱生物科技有限公司 一种酿酒酵母发酵生产d-塔格糖的方法
US11060119B2 (en) 2018-07-03 2021-07-13 Arzeda Corp. Methods and compositions for preparing tagatose from fructose
KR102329311B1 (ko) * 2018-09-28 2021-11-23 씨제이제일제당 주식회사 신규 과당-4-에피머화 효소 및 이를 이용한 타가토스의 제조 방법
CN113366112B (zh) 2018-10-19 2024-10-25 博努莫斯股份有限公司 塔格糖的酶法生产
KR102194285B1 (ko) * 2018-10-19 2020-12-23 씨제이제일제당 주식회사 신규 과당-4-에피머화 효소 및 이를 이용한 타가토스의 제조 방법
KR102219195B1 (ko) * 2019-08-14 2021-02-24 씨제이제일제당 주식회사 신규 과당-4-에피머화 효소 및 이를 이용한 타가토스의 제조 방법
KR102362873B1 (ko) * 2020-06-05 2022-02-11 건국대학교 산학협력단 타카투론산 에피머화 효소 변이체 및 이를 이용한 과당으로부터 타카토스의 생산방법
EP4464785A1 (de) 2023-05-15 2024-11-20 Annikki GmbH Verfahren zur herstellung von d-talitol, d-tagatose und d-psicose
EP4713470A1 (de) 2023-05-15 2026-03-25 Annikki GmbH Verfahren zur herstellung von d-talitol, d-tagatose und d-psicose
CN119932003B (zh) * 2024-12-19 2025-11-14 浙江工业大学 一种塔格糖-4-差向异构酶突变体及其在制备d-塔格糖中的应用

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Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11306303B2 (en) 2016-07-29 2022-04-19 Cj Cheiljedang Corporation Hexuronate C4-epimerase variant having improved D-tagatose conversion activity, and D-tagatose production method using same
KR101905469B1 (ko) 2016-07-29 2018-10-10 씨제이제일제당 주식회사 D-타가토스 전환 활성이 향상된 헥수론산 c4-에피머화 효소 변이체 및 이를 이용한 d-타가토스의 제조 방법
KR101905468B1 (ko) 2016-07-29 2018-10-10 씨제이제일제당 주식회사 D-타가토스 전환 활성이 향상된 헥수론산 c4-에피머화 효소 변이체 및 이를 이용한 d-타가토스의 제조 방법
KR101955103B1 (ko) 2016-07-29 2019-03-06 씨제이제일제당 (주) D-타가토스 전환 활성이 향상된 헥수론산 c4-에피머화 효소 변이체 및 이를 이용한 d-타가토스의 제조 방법
US10544439B2 (en) 2016-07-29 2020-01-28 Cj Cheiljedang Corporation Hexuronate C4-epimerase variant having improved D-tagatose conversion activity, and D-tagatose production method using same
US11499147B2 (en) 2016-07-29 2022-11-15 Cj Cheiljedang Corporation Nucleic acid encoding hexuronate C4-epimerase variant having improved D-tagatose conversion activity, and D-tagatose production method using same
KR20180013814A (ko) * 2016-07-29 2018-02-07 씨제이제일제당 (주) D-타가토스 전환 활성이 향상된 헥수론산 c4-에피머화 효소 변이체 및 이를 이용한 d-타가토스의 제조 방법
US10801020B2 (en) 2016-07-29 2020-10-13 Cj Cheiljedang Corporation Hexuronate C4-epimerase variant having improved d-tagatose conversion activity, and d-tagatose production method using same
US10947524B2 (en) 2016-07-29 2021-03-16 Cj Cheiljedang Corporation Hexuronate C4-epimerase variant having improved D-tagatose conversion activity, and D-tagatose production method using same
KR20200036144A (ko) * 2018-09-27 2020-04-07 씨제이제일제당 (주) 신규 과당-4-에피머화 효소 및 이를 이용한 타가토스의 제조 방법
KR102328650B1 (ko) 2018-09-27 2021-11-19 씨제이제일제당 주식회사 신규 과당-4-에피머화 효소 및 이를 이용한 타가토스의 제조 방법
WO2020067649A1 (ko) * 2018-09-27 2020-04-02 씨제이제일제당 (주) 신규 과당-4-에피머화 효소 및 이를 이용한 타가토스의 제조 방법
US11697832B2 (en) 2018-09-27 2023-07-11 Cj Cheiljedang Corporation Fructose-C4-epimerase and method of producing tagatose using the same

Also Published As

Publication number Publication date
EP3211078A4 (en) 2018-04-18
EP3211078B1 (en) 2019-03-27
US10544438B2 (en) 2020-01-28
EP3211078A1 (en) 2017-08-30
JP2017531438A (ja) 2017-10-26
CN107109394B (zh) 2021-01-15
UA119791C2 (uk) 2019-08-12
RU2017113926A3 (https=) 2018-11-22
KR20160047361A (ko) 2016-05-02
ES2721309T3 (es) 2019-07-30
CN107109394A (zh) 2017-08-29
WO2016064146A1 (ko) 2016-04-28
JP6518761B2 (ja) 2019-05-22
US20170306370A1 (en) 2017-10-26
RU2017113926A (ru) 2018-11-22
RU2701669C2 (ru) 2019-09-30

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