KR101599560B1 - 비경구 투여에 적합한 세펨 유도체를 함유하는 가용성 제형 - Google Patents

비경구 투여에 적합한 세펨 유도체를 함유하는 가용성 제형 Download PDF

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Publication number
KR101599560B1
KR101599560B1 KR1020107008731A KR20107008731A KR101599560B1 KR 101599560 B1 KR101599560 B1 KR 101599560B1 KR 1020107008731 A KR1020107008731 A KR 1020107008731A KR 20107008731 A KR20107008731 A KR 20107008731A KR 101599560 B1 KR101599560 B1 KR 101599560B1
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KR
South Korea
Prior art keywords
ceftaroline
delete delete
inn
formulation
arginine
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Expired - Fee Related
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KR1020107008731A
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English (en)
Korean (ko)
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KR20100075942A (ko
Inventor
마헨드라 데드히야
이공 지
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아스트라제네카 아베
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020107008731A 2007-09-21 2008-09-19 비경구 투여에 적합한 세펨 유도체를 함유하는 가용성 제형 Expired - Fee Related KR101599560B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97419407P 2007-09-21 2007-09-21
US60/974,194 2007-09-21

Publications (2)

Publication Number Publication Date
KR20100075942A KR20100075942A (ko) 2010-07-05
KR101599560B1 true KR101599560B1 (ko) 2016-03-03

Family

ID=40468354

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107008731A Expired - Fee Related KR101599560B1 (ko) 2007-09-21 2008-09-19 비경구 투여에 적합한 세펨 유도체를 함유하는 가용성 제형

Country Status (11)

Country Link
US (3) US20090082326A1 (enExample)
EP (2) EP2200618A4 (enExample)
JP (1) JP2010540448A (enExample)
KR (1) KR101599560B1 (enExample)
CN (3) CN103919720A (enExample)
AU (1) AU2008302201A1 (enExample)
BR (1) BRPI0816412A2 (enExample)
CA (1) CA2700263A1 (enExample)
MX (1) MX2010003112A (enExample)
RU (1) RU2537237C2 (enExample)
WO (1) WO2009039324A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20171176A1 (es) * 2009-09-21 2017-08-22 Astrazeneca Ab Composiciones y metodos para tratar infecciones bacterianas utilizando ceftarolina
TWI632921B (zh) * 2011-10-19 2018-08-21 大塚製藥股份有限公司 口服溶液
WO2016008393A1 (zh) * 2014-07-14 2016-01-21 正大天晴药业集团股份有限公司 头孢罗膦氨基酸盐及其结晶
CN104258403B (zh) * 2014-09-28 2017-03-01 刘宗侠 一种西洛他唑组合物及其制备方法
KR20170038214A (ko) * 2015-09-30 2017-04-07 (주)아모레퍼시픽 당산 및 플라보노이드를 포함하는 항균용 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028355A (en) * 1974-01-23 1977-06-07 Smithkline Corporation Cephalosporin purification process
GB8729574D0 (en) * 1987-12-18 1988-02-03 Fujisawa Pharmaceutical Co Water-soluble antibiotic composition
JP2761005B2 (ja) * 1988-11-02 1998-06-04 エーザイ株式会社 セファロスポリン含有注射用組成物
JPH02124822A (ja) * 1988-11-02 1990-05-14 Eisai Co Ltd セファロスポリン含有注射用組成物
ES2121745T3 (es) * 1989-03-30 1998-12-16 Pfizer Cefalosporinas y sus homologos, procedimiento para su preparacion y composiciones farmaceuticas.
ES2059947T3 (es) * 1989-09-30 1994-11-16 Eisai Co Ltd Preparados inyectables que contienen cefalosporina y utilizacion de los mismos.
JPH0840907A (ja) * 1994-08-03 1996-02-13 Meiji Seika Kaisha Ltd セファロスポリン注射剤
TW473479B (en) * 1997-12-19 2002-01-21 Takeda Chemical Industries Ltd Phosphonocephem derivatives, their production and use
US7527807B2 (en) * 2000-06-21 2009-05-05 Cubist Pharmaceuticals, Inc. Compositions and methods for increasing the oral absorption of antimicrobials
DK1310502T3 (da) * 2000-08-10 2009-09-07 Takeda Pharmaceutical Phosphonocephem-forbindelse
JP3586226B2 (ja) * 2000-08-10 2004-11-10 武田薬品工業株式会社 ホスホノセフェム化合物
WO2004096279A1 (ja) * 2003-04-28 2004-11-11 Takeda Pharmaceutical Company Limited 注射用組成物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Bioorganic & Medicinal Chemistry, 2003, Vol. 11, No. 11, pp. 2427-2437*

Also Published As

Publication number Publication date
KR20100075942A (ko) 2010-07-05
US20090082326A1 (en) 2009-03-26
EP2200618A1 (en) 2010-06-30
EP2952195A1 (en) 2015-12-09
RU2010115268A (ru) 2011-10-27
RU2537237C2 (ru) 2014-12-27
CN102935065A (zh) 2013-02-20
AU2008302201A1 (en) 2009-03-26
WO2009039324A1 (en) 2009-03-26
US20120010180A1 (en) 2012-01-12
US20150196572A1 (en) 2015-07-16
EP2200618A4 (en) 2010-11-03
BRPI0816412A2 (pt) 2017-05-16
CA2700263A1 (en) 2009-03-26
JP2010540448A (ja) 2010-12-24
CN101868240A (zh) 2010-10-20
MX2010003112A (es) 2010-08-11
CN103919720A (zh) 2014-07-16

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